ATE320001T1 - Durch fluoreszierenden polymer markierte konjugate und zwischen produkte - Google Patents
Durch fluoreszierenden polymer markierte konjugate und zwischen produkteInfo
- Publication number
- ATE320001T1 ATE320001T1 AT94923455T AT94923455T ATE320001T1 AT E320001 T1 ATE320001 T1 AT E320001T1 AT 94923455 T AT94923455 T AT 94923455T AT 94923455 T AT94923455 T AT 94923455T AT E320001 T1 ATE320001 T1 AT E320001T1
- Authority
- AT
- Austria
- Prior art keywords
- polymer
- conjugates
- fluorescent polymer
- intermediate products
- fluorescent
- Prior art date
Links
- 229920001109 fluorescent polymer Polymers 0.000 title abstract 3
- 239000013067 intermediate product Substances 0.000 title 1
- 229920000642 polymer Polymers 0.000 abstract 2
- 230000009870 specific binding Effects 0.000 abstract 2
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000000159 protein binding assay Methods 0.000 abstract 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical group O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Luminescent Compositions (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Polyamides (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Graft Or Block Polymers (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9114993A | 1993-07-13 | 1993-07-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE320001T1 true ATE320001T1 (de) | 2006-03-15 |
Family
ID=22226323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94923455T ATE320001T1 (de) | 1993-07-13 | 1994-07-13 | Durch fluoreszierenden polymer markierte konjugate und zwischen produkte |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0708837B1 (de) |
| JP (1) | JPH09500411A (de) |
| AT (1) | ATE320001T1 (de) |
| AU (1) | AU7331794A (de) |
| CA (1) | CA2172999A1 (de) |
| DE (1) | DE69434649T2 (de) |
| ES (1) | ES2259791T3 (de) |
| WO (1) | WO1995002700A1 (de) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6319670B1 (en) | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
| US5994143A (en) * | 1996-02-01 | 1999-11-30 | Abbott Laboratories | Polymeric fluorophores enhanced by moieties providing a hydrophobic and conformationally restrictive microenvironment |
| FR2757162B1 (fr) * | 1996-12-12 | 1999-03-26 | Cis Bio Int | Conjugues fluorescents non agreges |
| US5877310A (en) * | 1997-04-25 | 1999-03-02 | Carnegie Mellon University | Glycoconjugated fluorescent labeling reagents |
| AT408150B (de) * | 2000-04-14 | 2001-09-25 | Oesterr Forsch Seibersdorf | Verfahren zur immobilisierung eines analyten an einer festen oberfläche |
| AU2001278145B2 (en) * | 2000-08-04 | 2006-09-14 | Sensors For Medicine And Science, Inc. | Detection of analytes in aqueous environments |
| US7144950B2 (en) | 2003-09-17 | 2006-12-05 | The Regents Of The University Of California | Conformationally flexible cationic conjugated polymers |
| US9371559B2 (en) | 2002-06-20 | 2016-06-21 | The Regents Of The University Of California | Compositions for detection and analysis of polynucleotides using light harvesting multichromophores |
| US10001475B2 (en) | 2002-06-20 | 2018-06-19 | The Regents Of The University Of California | Light harvesting multichromophore compositions and methods of using the same |
| EP2316971A1 (de) | 2002-08-26 | 2011-05-04 | The Regents of the University of California | Verfahren und Zusammensetzungen zum Nachweis und zur Analyse von Polynuckleotiden unter Benutzung von lichtsammelnden Multichromophoren. |
| EP2161343B1 (de) | 2003-02-13 | 2013-10-23 | The Regents Of the University of California | Verfahren und Zusammensetzungen zum Erkennen und Analysieren von polynucleotid-bindenden Protein-Wechselwirkungen mit lichtnutzenden Multichromophoren |
| FR2878853B1 (fr) * | 2004-12-07 | 2007-03-16 | Biocydex Soc Par Actions Simpl | Procede d'obtention d'un complexe fluorescent, complexe obtenu et utilisation |
| CA2594458C (en) | 2005-01-10 | 2016-08-23 | The Regents Of The University Of California | Cationic conjugated polymers suitable for strand-specific polynucleotide detection in homogeneous and solid state assays |
| WO2006074482A2 (en) | 2005-01-10 | 2006-07-13 | The Regents Of The University Of California | Methods and kits for strand-specific polynucleotide detection with cationic multichromophores |
| US7666594B2 (en) | 2005-01-31 | 2010-02-23 | The Regents Of The University Of California | Methods for assaying a sample for an aggregant |
| JP5420414B2 (ja) | 2006-10-06 | 2014-02-19 | シリゲン グループ リミテッド | 指向性バイオマーカシグナル増幅用の蛍光方法および材料 |
| CN101730549B (zh) * | 2007-05-09 | 2015-12-09 | 日东电工株式会社 | 与铂类药物结合的聚合物 |
| ES2731432T3 (es) * | 2007-05-23 | 2019-11-15 | Ventana Med Syst Inc | Transportadores poliméricos para inmunohistoquímica e hibridación in situ |
| SG177355A1 (en) | 2009-06-26 | 2012-02-28 | Sirigen Inc | Signal amplified biological detection with conjugated polymers |
| ES2977359T3 (es) | 2010-01-19 | 2024-08-22 | Sirigen Ii Ltd | Nuevos reactivos para la amplificación dirigida de la señal de un biomarcador |
| JP6190534B2 (ja) | 2013-08-22 | 2017-08-30 | ソニー株式会社 | 水溶性蛍光染料又は有色染料及びその使用方法 |
| EP3094687B1 (de) | 2014-01-16 | 2020-02-12 | Sony Corporation | Wasserlösliche fluoreszierende oder gefärbte farbstoffe |
| JP6344647B2 (ja) * | 2014-08-20 | 2018-06-20 | 学校法人日本大学 | 蛍光物質及びその製造方法 |
| KR102676814B1 (ko) | 2015-02-26 | 2024-06-21 | 소니그룹주식회사 | 접합 그룹을 포함하는 수용성 형광 또는 착색 염료 |
| JP6982500B2 (ja) | 2015-02-26 | 2021-12-17 | ソニーグループ株式会社 | フェニルエチニルナフタレン染料およびそれらの使用方法 |
| US10865310B2 (en) | 2015-05-11 | 2020-12-15 | Sony Corporation Of America | Ultra bright dimeric or polymeric dyes |
| CN105237658B (zh) * | 2015-09-24 | 2018-05-22 | 荆楚理工学院 | 一种荧光修饰环糊精及其制备方法和应用 |
| CN107580618A (zh) | 2016-04-01 | 2018-01-12 | 索尼公司 | 超亮二聚或多聚染料 |
| CN109415574B (zh) | 2016-04-01 | 2021-05-28 | 索尼公司 | 具有刚性间隔基团的超亮二聚体或聚合物染料 |
| JP7069033B2 (ja) | 2016-04-06 | 2022-05-17 | ソニーグループ株式会社 | スペーシングリンカー基を有する超明色ダイマーまたはポリマー染料 |
| JP7527537B2 (ja) | 2016-05-10 | 2024-08-05 | ソニーグループ株式会社 | ペプチド骨格を有する超明色ポリマー染料 |
| WO2017197014A2 (en) * | 2016-05-10 | 2017-11-16 | Sony Corporation | Compositions comprising a polymeric dye and a cyclodextrin and uses thereof |
| AU2017264861B2 (en) | 2016-05-11 | 2021-09-23 | Sony Group Corporation | Ultra bright dimeric or polymeric dyes |
| WO2017214165A1 (en) | 2016-06-06 | 2017-12-14 | Sony Corporation | Ionic polymers comprising fluorescent or colored reporter groups |
| US12018159B2 (en) | 2016-07-29 | 2024-06-25 | Sony Group Corporation | Ultra bright dimeric or polymeric dyes and methods for preparation of the same |
| JP7041884B2 (ja) * | 2017-08-29 | 2022-03-25 | 東芝インフラシステムズ株式会社 | 水質分析用試薬及び水質分析方法 |
| JP7551056B2 (ja) | 2017-10-05 | 2024-09-17 | ソニーグループ株式会社 | プログラマブルなポリマー薬物 |
| EP3691689A1 (de) | 2017-10-05 | 2020-08-12 | Sony Corporation | Programmierbare dendritische arzneimittel |
| JP2021503450A (ja) | 2017-11-16 | 2021-02-12 | ソニー株式会社 | プログラム可能なポリマー薬 |
| JP7813098B2 (ja) | 2018-01-12 | 2026-02-12 | ソニーグループ株式会社 | 生物学的に活性な化合物を含む剛性間隔基を有するポリマー |
| JP2021510698A (ja) | 2018-01-12 | 2021-04-30 | ソニー株式会社 | 生物学的に活性な化合物を含むホスホアルキルリボースポリマー |
| CN111565757A (zh) | 2018-01-12 | 2020-08-21 | 索尼公司 | 包含生物活性化合物的磷酸烷基聚合物 |
| KR102742386B1 (ko) | 2018-03-19 | 2024-12-16 | 소니그룹주식회사 | 형광 신호 향상을 위한 2가 금속의 사용 |
| WO2019182766A1 (en) | 2018-03-21 | 2019-09-26 | Sony Corporation | Polymeric tandem dyes with linker groups |
| KR102854332B1 (ko) | 2018-06-27 | 2025-09-03 | 소니그룹주식회사 | 디옥시리보오스를 포함하는 링커 군을 갖는 중합체성 염료 |
| EP3820944A1 (de) | 2018-07-13 | 2021-05-19 | Sony Corporation | Polymere farbstoffe mit einem gerüst mit organophosphateinheiten |
| WO2021062176A2 (en) | 2019-09-26 | 2021-04-01 | Sony Corporation | Polymeric tandem dyes with linker groups |
| JP7816141B2 (ja) | 2019-09-30 | 2026-02-18 | ソニーグループ株式会社 | ヌクレオチドプローブ |
| EP4256078A1 (de) | 2020-12-07 | 2023-10-11 | Sony Group Corporation | Abstandslinkergruppendesign zur helligkeitsverstärkung in dimeren oder polymeren farbstoffen |
| WO2022182837A1 (en) * | 2021-02-26 | 2022-09-01 | Collins James J | Devices and methods for rapid nucleic acid preparation and detection |
| CN114344483A (zh) * | 2022-01-18 | 2022-04-15 | 西安交通大学 | 基于超小分子H-dot纳米载药系统的肺癌诊疗一体化的靶向纳米药物及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4169137A (en) * | 1974-12-20 | 1979-09-25 | Block Engineering, Inc. | Antigen detecting reagents |
| US5068227A (en) * | 1989-01-18 | 1991-11-26 | Cyclex, Inc. | Cyclodextrins as carriers |
| WO1991002040A1 (en) * | 1989-08-04 | 1991-02-21 | Kosak Kenneth M | Cyclodextrin labels for nucleic acid and biochemical analysis |
| WO1991005605A1 (en) * | 1989-10-10 | 1991-05-02 | Kosak Kenneth M | Cyclodextrin labels for immunoassay and biochemical analysis |
-
1994
- 1994-07-13 EP EP94923455A patent/EP0708837B1/de not_active Expired - Lifetime
- 1994-07-13 AT AT94923455T patent/ATE320001T1/de not_active IP Right Cessation
- 1994-07-13 ES ES94923455T patent/ES2259791T3/es not_active Expired - Lifetime
- 1994-07-13 JP JP7504687A patent/JPH09500411A/ja not_active Ceased
- 1994-07-13 AU AU73317/94A patent/AU7331794A/en not_active Abandoned
- 1994-07-13 CA CA002172999A patent/CA2172999A1/en not_active Abandoned
- 1994-07-13 WO PCT/US1994/007855 patent/WO1995002700A1/en not_active Ceased
- 1994-07-13 DE DE69434649T patent/DE69434649T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0708837A1 (de) | 1996-05-01 |
| WO1995002700A1 (en) | 1995-01-26 |
| EP0708837A4 (de) | 2002-11-20 |
| AU7331794A (en) | 1995-02-13 |
| DE69434649T2 (de) | 2007-02-22 |
| CA2172999A1 (en) | 1995-01-26 |
| JPH09500411A (ja) | 1997-01-14 |
| EP0708837B1 (de) | 2006-03-08 |
| DE69434649D1 (de) | 2006-05-04 |
| ES2259791T3 (es) | 2006-10-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69434649D1 (de) | Durch fluoreszierenden polymer markierte konjugate und zwischen produkte | |
| CA2150925A1 (en) | Improved synthesis of polymer bio-active conjugates | |
| ATE237138T1 (de) | Durch gruppen erweiterte fluorophore polymere, die eine hydrophobe und konformativ eingeschrankte mikroumgebung schaffen | |
| AU3653093A (en) | Dendritic macromolecule, process for preparation thereof and use thereof | |
| AU2002364453A1 (en) | Thermoplastic polymer composition comprising a hyperbranched polymer and articles made using said composition | |
| AR070938A2 (es) | Composiciones poly-hema de baja polidispersion | |
| SG55079A1 (en) | Multivalent single chain antibodies | |
| AU8612191A (en) | Poly-beta-hydroxy alkanoate (pha) copolymer, method of its production, the microbe which produces it, and pha copolymer blend | |
| DE69718802D1 (de) | Supramolekular polymere | |
| DK1627880T3 (da) | Boronester og -syreforbindelser samt syntese og anvendelser | |
| WO1999041273A3 (en) | Pna and dna conjugates and methods for preparation thereof | |
| DK0807178T3 (da) | Mycobaktielle proteiner, mikroorganismer producerende samme og anvendelser af nævnte proteiner i vacciner og til påvisning af tuberkulose | |
| BR9301415A (pt) | Produtos de polimeros,processo para o tratamento de couro e couro | |
| BR9910207A (pt) | Produtos de condensação de knoevenagel monoméricos, oligoméricos e poliméricos | |
| BR9711117A (pt) | Oligossacarídios modificados. | |
| BR9709350A (pt) | Membro de ligação especìfico, comp[osição farmacêutica, ácido nuclieco, célula hospedeira, uso de um membro de ligação especìfico e processo para sua produção | |
| DK1412518T3 (da) | Sorterings- og immobiliseringssystem for nukleinsyrer under anvendelse af syntetiske bindingssystemer | |
| ID22537A (id) | Sistem adesif untuk metoda pengikatan adesif langkah tunggal atau banyak, metoda untuk pengikatan adesif barang cetakan | |
| ATE304709T1 (de) | Substanzen mit verzweigten linkermolekülen | |
| BR9507292A (pt) | Processo para a preparação de aglutinantes de laca que secam ao ara diluíveis na água e sua aplicação | |
| TW367335B (en) | Cyclo-olefin polymers and preparation process thereof | |
| ATE260337T1 (de) | Neue oligomere konjugate zum transfer biologischer moleküle in zellen | |
| KR960703938A (ko) | 카르바메이트 누클레오시드간 결합을 갖는 축적 블록 및 이로부터 유도된 올리고누클레오티드(building blocks with carbamate internucleoside linkages and novel oligonucleotides derived therefrom) | |
| AU1856300A (en) | Derivatisation of support surfaces | |
| DK0529175T3 (da) | Konjugater chelaret med paramagnetiske metaller til målsøgning |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |