ATE237322T1 - Nichtpolares nitroglycerinspray zur bukkalen verabreichung - Google Patents

Nichtpolares nitroglycerinspray zur bukkalen verabreichung

Info

Publication number
ATE237322T1
ATE237322T1 AT97907785T AT97907785T ATE237322T1 AT E237322 T1 ATE237322 T1 AT E237322T1 AT 97907785 T AT97907785 T AT 97907785T AT 97907785 T AT97907785 T AT 97907785T AT E237322 T1 ATE237322 T1 AT E237322T1
Authority
AT
Austria
Prior art keywords
polar
nitroglycerin
buccal administration
nitroglycerin spray
spray
Prior art date
Application number
AT97907785T
Other languages
English (en)
Inventor
Harry A Dugger Iii
Original Assignee
Novadel Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novadel Pharma Inc filed Critical Novadel Pharma Inc
Application granted granted Critical
Publication of ATE237322T1 publication Critical patent/ATE237322T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
AT97907785T 1996-04-12 1997-02-21 Nichtpolares nitroglycerinspray zur bukkalen verabreichung ATE237322T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/630,064 US5869082A (en) 1996-04-12 1996-04-12 Buccal, non-polar spray for nitroglycerin
PCT/US1997/002794 WO1997038687A1 (en) 1996-04-12 1997-02-21 Buccal, non-polar spray for nitroglycerin

Publications (1)

Publication Number Publication Date
ATE237322T1 true ATE237322T1 (de) 2003-05-15

Family

ID=24525605

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97907785T ATE237322T1 (de) 1996-04-12 1997-02-21 Nichtpolares nitroglycerinspray zur bukkalen verabreichung

Country Status (10)

Country Link
US (1) US5869082A (de)
EP (1) EP0927032B1 (de)
AT (1) ATE237322T1 (de)
AU (1) AU1969397A (de)
CA (1) CA2251564C (de)
DE (1) DE69721020T2 (de)
DK (1) DK0927032T3 (de)
ES (1) ES2197990T3 (de)
PT (1) PT927032E (de)
WO (1) WO1997038687A1 (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030190286A1 (en) * 1997-10-01 2003-10-09 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating allergies or asthma
US20050287075A1 (en) * 1997-10-01 2005-12-29 Dugger Harry A Iii Buccal, polar and non-polar spray or capsule containing drugs for treating pain
US20040136913A1 (en) * 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing sumatriptan
US20050002867A1 (en) * 1997-10-01 2005-01-06 Novadel Pharma Inc. Buccal, polar and non-polar sprays containing propofol
AU4894697A (en) 1997-10-01 1999-04-23 Flemington Pharmaceutical Corporation Buccal, polar and non-polar spray or capsule
US20030095926A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the gastrointestinal tract or urinary tract
US20090162300A1 (en) * 1997-10-01 2009-06-25 Dugger Iii Harry A Buccal, polar and non-polar spray containing alprazolam
US20030095925A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders
US20040136914A1 (en) 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing ondansetron
US20050180923A1 (en) * 1997-10-01 2005-08-18 Dugger Harry A.Iii Buccal, polar and non-polar spray containing testosterone
US20030077229A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs
US20030077228A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating endocrine disorders
US20040136915A1 (en) * 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing atropine
US20030082107A1 (en) * 1997-10-01 2003-05-01 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer
US20050163719A1 (en) * 1997-10-01 2005-07-28 Dugger Harry A.Iii Buccal, polar and non-polar spray containing diazepam
US20030095927A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating muscular and skeletal disorders
US20030077227A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
US7632517B2 (en) * 1997-10-01 2009-12-15 Novadel Pharma Inc. Buccal, polar and non-polar spray containing zolpidem
US20040141923A1 (en) * 1997-10-01 2004-07-22 Dugger Harry A. Buccal, polar and non-polar spray containing alprazolam
US20030185761A1 (en) * 1997-10-01 2003-10-02 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating pain
US20050281752A1 (en) * 1997-10-01 2005-12-22 Dugger Harry A Iii Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
US20030029208A1 (en) * 2001-08-13 2003-02-13 Ralph Merrem Portable electronic device physical security
US20060073174A1 (en) * 2001-08-16 2006-04-06 Access Pharmaceuticals, Inc. Adherent and erodible film to treat a moist surface of a body tissue
US6585997B2 (en) 2001-08-16 2003-07-01 Access Pharmaceuticals, Inc. Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds
US7138133B2 (en) 2001-10-10 2006-11-21 The Procter & Gamble Company Orally administered liquid compositions
WO2005004989A2 (en) * 2003-07-01 2005-01-20 Todd Maibach Film comprising therapeutic agents
US7013685B2 (en) * 2003-07-23 2006-03-21 Acco Brands Usa Llc Computer physical security device with retractable cable
KR20140104986A (ko) * 2004-02-17 2014-08-29 트랜스셉트 파마슈티칼스, 인코포레이티드 구강 점막을 가로지르는 수면제 전달용 조성물 및 이의 사용 방법
EP2767163A1 (de) 2005-02-17 2014-08-20 Abbott Laboratories Transmukosale Verabreichung von Arzneimittelzusammensetzungen zur Behandlung und Vorbeugung von Erkrankungen bei Tieren
US20070225322A1 (en) * 2005-05-25 2007-09-27 Transoral Pharmaceuticals, Inc. Compositions and methods for treating middle-of-the night insomnia
WO2006128022A2 (en) * 2005-05-25 2006-11-30 Transcept Pharmaceuticals, Inc. Solid compositions and methods for treating middle-of-the night insomnia
US20070287740A1 (en) * 2005-05-25 2007-12-13 Transcept Pharmaceuticals, Inc. Compositions and methods of treating middle-of-the night insomnia
EP2015632B1 (de) * 2006-04-19 2015-12-02 Mist Pharmaceuticals, LLC Stabile wässrig-alkoholische mundsprayformulierungen und verfahren
JP2010513525A (ja) * 2006-12-22 2010-04-30 ノヴァデル ファーマ インコーポレイテッド 安定な抗嘔吐経口噴霧製剤および方法
EP2112923A1 (de) 2007-01-22 2009-11-04 Targacept Inc. Intranasale, orale und sublinguale verabreichung von metanikotin-analogen
US20100215774A1 (en) * 2007-02-09 2010-08-26 Todd Maibach Film comprising nitroglycerin
JP2010526837A (ja) * 2007-05-10 2010-08-05 ノヴァデル ファーマ インコーポレイテッド 抗不眠症組成物および方法
US20090004254A1 (en) * 2007-06-19 2009-01-01 Todd Maibach Film comprising active drugs
US7985325B2 (en) * 2007-10-30 2011-07-26 Novellus Systems, Inc. Closed contact electroplating cup assembly
DE202008007318U1 (de) 2008-03-14 2008-07-31 G. Pohl-Boskamp Gmbh & Co. Kg Langzeitstabile pharmazeutische Zubereitung mit dem Wirkstoff Glyceroltrinitrat
DE202008008079U1 (de) * 2008-06-16 2008-09-04 G. Pohl-Boskamp Gmbh & Co. Kg Pharmazeutische Zubereitung in Wasserdampf durchlässigen Behältern mit verbesserter Stabilität
CN102770152B (zh) 2009-11-25 2016-07-06 阿瑞斯根股份有限公司 肽类的粘膜递送
EP2600837A1 (de) 2010-08-03 2013-06-12 G. Pohl-Boskamp GmbH & Co. KG Verwendung von glyceryltrinitrat zur behandlung von hämatomen
CA2827714A1 (en) 2011-02-25 2012-08-30 G. Pohl-Boskamp Gmbh & Co. Kg Packaging of solid pharmaceutical preparations containing the active substance glyceryl trinitrate
EP2526971A1 (de) 2011-05-25 2012-11-28 ArisGen SA Mukosale Freisetzung von Arzneimitteln
EP2668947B1 (de) 2012-05-31 2016-11-30 G. Pohl-Boskamp GmbH & Co. KG Arteriogeneseinduktion mit einem stickstoffmonoxid-donor, z.b. nitroglycerin
US9248099B2 (en) 2012-05-31 2016-02-02 Desmoid Aktiengesellschaft Use of stabilized granules containing glyceryl trinitrate for arteriogenesis
EP2878310B1 (de) 2013-11-29 2017-01-11 G. Pohl-Boskamp GmbH & Co. KG Sprühbare wässrige Zusammensetzung mit Nitroglycerin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE632504A (de) * 1962-05-24
DE3246081A1 (de) * 1982-12-13 1984-06-14 G. Pohl-Boskamp GmbH & Co Chemisch-pharmazeutische Fabrik, 2214 Hohenlockstedt Nitroglycerin-spray
DE4007705C1 (de) * 1990-03-10 1991-09-26 G. Pohl-Boskamp Gmbh & Co. Chemisch-Pharmazeutische Fabrik, 2214 Hohenlockstedt, De
WO1991016929A1 (en) * 1990-05-10 1991-11-14 Novo Nordisk A/S A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols
DE4038203A1 (de) * 1990-11-30 1992-06-04 Kali Chemie Pharma Gmbh Pharmazeutische spray-zubereitungen mit coronaraktiven wirkstoffen

Also Published As

Publication number Publication date
WO1997038687A1 (en) 1997-10-23
EP0927032B1 (de) 2003-04-16
ES2197990T3 (es) 2004-01-16
DE69721020T2 (de) 2003-12-04
CA2251564A1 (en) 1997-10-23
DK0927032T3 (da) 2003-07-14
DE69721020D1 (de) 2003-05-22
US5869082A (en) 1999-02-09
EP0927032A1 (de) 1999-07-07
CA2251564C (en) 2007-01-09
PT927032E (pt) 2003-07-31
AU1969397A (en) 1997-11-07

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