ATE237322T1 - Nichtpolares nitroglycerinspray zur bukkalen verabreichung - Google Patents

Nichtpolares nitroglycerinspray zur bukkalen verabreichung

Info

Publication number: ATE237322T1
Authority: AT; Austria
Prior art keywords: polar; nitroglycerin; buccal administration; nitroglycerin spray; spray
Prior art date: 1996-04-12

Application number

AT97907785T

Other languages

English (en)

Inventor

Harry A Dugger Iii

Original Assignee

Novadel Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-12

Filing date

1997-02-21

Publication date

2003-05-15

1997-02-21 Application filed by Novadel Pharma Inc filed Critical Novadel Pharma Inc

2003-05-15 Application granted granted Critical

2003-05-15 Publication of ATE237322T1 publication Critical patent/ATE237322T1/de

Links

SNIOPGDIGTZGOP-UHFFFAOYSA-N Nitroglycerin Chemical compound [O-][N+](=O)OCC(O[N+]([O-])=O)CO[N+]([O-])=O SNIOPGDIGTZGOP-UHFFFAOYSA-N 0.000 title abstract 3
239000000006 Nitroglycerin Substances 0.000 title abstract 3
229960003711 glyceryl trinitrate Drugs 0.000 title abstract 3
239000000443 aerosol Substances 0.000 abstract 2
239000012454 non-polar solvent Substances 0.000 abstract 2
239000007921 spray Substances 0.000 abstract 2
238000010521 absorption reaction Methods 0.000 abstract 1
239000000796 flavoring agent Substances 0.000 abstract 1
235000013355 food flavoring agent Nutrition 0.000 abstract 1
210000002200 mouth mucosa Anatomy 0.000 abstract 1
239000003380 propellant Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates

Landscapes

Health & Medical Sciences (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Physiology (AREA)
Nutrition Science (AREA)
Emergency Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

AT97907785T 1996-04-12 1997-02-21 Nichtpolares nitroglycerinspray zur bukkalen verabreichung ATE237322T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/630,064 US5869082A (en)	1996-04-12	1996-04-12	Buccal, non-polar spray for nitroglycerin
PCT/US1997/002794 WO1997038687A1 (en)	1996-04-12	1997-02-21	Buccal, non-polar spray for nitroglycerin

Publications (1)

Publication Number	Publication Date
ATE237322T1 true ATE237322T1 (de)	2003-05-15

Family

ID=24525605

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97907785T ATE237322T1 (de)	1996-04-12	1997-02-21	Nichtpolares nitroglycerinspray zur bukkalen verabreichung

Country Status (10)

Country	Link
US (1)	US5869082A (de)
EP (1)	EP0927032B1 (de)
AT (1)	ATE237322T1 (de)
AU (1)	AU1969397A (de)
CA (1)	CA2251564C (de)
DE (1)	DE69721020T2 (de)
DK (1)	DK0927032T3 (de)
ES (1)	ES2197990T3 (de)
PT (1)	PT927032E (de)
WO (1)	WO1997038687A1 (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030190286A1 (en) *	1997-10-01	2003-10-09	Dugger Harry A.	Buccal, polar and non-polar spray or capsule containing drugs for treating allergies or asthma
US20030095927A1 (en) *	1997-10-01	2003-05-22	Dugger Harry A.	Buccal, polar and non-polar spray or capsule containing drugs for treating muscular and skeletal disorders
US20090162300A1 (en) *	1997-10-01	2009-06-25	Dugger Iii Harry A	Buccal, polar and non-polar spray containing alprazolam
US7632517B2 (en) *	1997-10-01	2009-12-15	Novadel Pharma Inc.	Buccal, polar and non-polar spray containing zolpidem
US20030077228A1 (en) *	1997-10-01	2003-04-24	Dugger Harry A.	Buccal, polar and non-polar spray or capsule containing drugs for treating endocrine disorders
US20030095926A1 (en) *	1997-10-01	2003-05-22	Dugger Harry A.	Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the gastrointestinal tract or urinary tract
US20050163719A1 (en) *	1997-10-01	2005-07-28	Dugger Harry A.Iii	Buccal, polar and non-polar spray containing diazepam
US20030077227A1 (en) *	1997-10-01	2003-04-24	Dugger Harry A.	Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
US20040141923A1 (en) *	1997-10-01	2004-07-22	Dugger Harry A.	Buccal, polar and non-polar spray containing alprazolam
US20050287075A1 (en) *	1997-10-01	2005-12-29	Dugger Harry A Iii	Buccal, polar and non-polar spray or capsule containing drugs for treating pain
US20040136914A1 (en)	1997-10-01	2004-07-15	Dugger Harry A.	Buccal, polar and non-polar spray containing ondansetron
US20040136915A1 (en) *	1997-10-01	2004-07-15	Dugger Harry A.	Buccal, polar and non-polar spray containing atropine
US20050002867A1 (en) *	1997-10-01	2005-01-06	Novadel Pharma Inc.	Buccal, polar and non-polar sprays containing propofol
US20040136913A1 (en) *	1997-10-01	2004-07-15	Dugger Harry A.	Buccal, polar and non-polar spray containing sumatriptan
US20030082107A1 (en) *	1997-10-01	2003-05-01	Dugger Harry A.	Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer
US20050180923A1 (en) *	1997-10-01	2005-08-18	Dugger Harry A.Iii	Buccal, polar and non-polar spray containing testosterone
US20030095925A1 (en) *	1997-10-01	2003-05-22	Dugger Harry A.	Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders
US20030185761A1 (en) *	1997-10-01	2003-10-02	Dugger Harry A.	Buccal, polar and non-polar spray or capsule containing drugs for treating pain
US20030077229A1 (en) *	1997-10-01	2003-04-24	Dugger Harry A.	Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs
EP1952802A3 (de)	1997-10-01	2009-06-17	Novadel Pharma Inc.	Oraler, polarer und nicht-polarer Spray bzw. Kapsel
US20050281752A1 (en) *	1997-10-01	2005-12-22	Dugger Harry A Iii	Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
US20030029208A1 (en) *	2001-08-13	2003-02-13	Ralph Merrem	Portable electronic device physical security
US20060073174A1 (en) *	2001-08-16	2006-04-06	Access Pharmaceuticals, Inc.	Adherent and erodible film to treat a moist surface of a body tissue
US6585997B2 (en)	2001-08-16	2003-07-01	Access Pharmaceuticals, Inc.	Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds
US7138133B2 (en)	2001-10-10	2006-11-21	The Procter & Gamble Company	Orally administered liquid compositions
US20070059346A1 (en) *	2003-07-01	2007-03-15	Todd Maibach	Film comprising therapeutic agents
JP2006528392A (ja) *	2003-07-23	2006-12-14	アコブランズインコーポレーティッド	引込み可能なケーブルを有するコンピュータ物理的安全装置
EP1715853A4 (de) *	2004-02-17	2012-07-18	Transcept Pharmaceuticals Inc	Zusammensetzungen zur abgabe von hypnotika im bereich der mundschleimhäute und verwendungsverfahren davon
ES2490595T3 (es)	2005-02-17	2014-09-04	Abbott Laboratories	Administración transmucosal de composiciones de fármacos para tratar y prevenir trastornos en animales
US20070225322A1 (en) *	2005-05-25	2007-09-27	Transoral Pharmaceuticals, Inc.	Compositions and methods for treating middle-of-the night insomnia
US20070287740A1 (en) *	2005-05-25	2007-12-13	Transcept Pharmaceuticals, Inc.	Compositions and methods of treating middle-of-the night insomnia
US20070123562A1 (en) *	2005-05-25	2007-05-31	Transoral Pharmaceuticals, Inc.	Compositions and methods for treating middle-of-the-night insomnia
EP2015632B1 (de) *	2006-04-19	2015-12-02	Mist Pharmaceuticals, LLC	Stabile wässrig-alkoholische mundsprayformulierungen und verfahren
CA2673049C (en) *	2006-12-22	2016-02-23	Novadel Pharma Inc.	Stable anti-nausea oral spray formulations and methods
WO2008091588A1 (en)	2007-01-22	2008-07-31	Targacept, Inc.	Intranasal, buccal, and sublingual administration of metanicotine analogs
US20100215774A1 (en) *	2007-02-09	2010-08-26	Todd Maibach	Film comprising nitroglycerin
CA2687085A1 (en) *	2007-05-10	2008-11-20	Novadel Pharma Inc.	Anti-insomnia compositions and methods
US20090004254A1 (en) *	2007-06-19	2009-01-01	Todd Maibach	Film comprising active drugs
US7985325B2 (en) *	2007-10-30	2011-07-26	Novellus Systems, Inc.	Closed contact electroplating cup assembly
DE202008007318U1 (de)	2008-03-14	2008-07-31	G. Pohl-Boskamp Gmbh & Co. Kg	Langzeitstabile pharmazeutische Zubereitung mit dem Wirkstoff Glyceroltrinitrat
DE202008008079U1 (de) *	2008-06-16	2008-09-04	G. Pohl-Boskamp Gmbh & Co. Kg	Pharmazeutische Zubereitung in Wasserdampf durchlässigen Behältern mit verbesserter Stabilität
WO2011064316A2 (en)	2009-11-25	2011-06-03	Paolo Botti	Mucosal delivery of peptides
ES2582309T3 (es)	2010-08-03	2016-09-12	G. Pohl-Boskamp Gmbh & Co. Kg	Uso de trinitrato de glicerilo para el tratamiento de edema traumático
WO2012113564A1 (en)	2011-02-25	2012-08-30	G. Pohl-Boskamp Gmbh & Co. Kg	Stabilized granules containing glyceryl trinitrate
EP2526971A1 (de)	2011-05-25	2012-11-28	ArisGen SA	Mukosale Freisetzung von Arzneimitteln
PL2668947T3 (pl)	2012-05-31	2017-06-30	G. Pohl-Boskamp Gmbh & Co. Kg	Indukcja arteriogenezy donorem NO, takim jak nitrogliceryna
US9248099B2 (en)	2012-05-31	2016-02-02	Desmoid Aktiengesellschaft	Use of stabilized granules containing glyceryl trinitrate for arteriogenesis
EP2878310B1 (de)	2013-11-29	2017-01-11	G. Pohl-Boskamp GmbH & Co. KG	Sprühbare wässrige Zusammensetzung mit Nitroglycerin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE632504A (de) *	1962-05-24
DE3246081A1 (de) *	1982-12-13	1984-06-14	G. Pohl-Boskamp GmbH & Co Chemisch-pharmazeutische Fabrik, 2214 Hohenlockstedt	Nitroglycerin-spray
DE4007705C1 (de) *	1990-03-10	1991-09-26	G. Pohl-Boskamp Gmbh & Co. Chemisch-Pharmazeutische Fabrik, 2214 Hohenlockstedt, De
ATE164080T1 (de) *	1990-05-10	1998-04-15	Bechgaard Int Res	Pharmazeutische zubereitung enthaltend n- glykofurole und n-äthylenglykole
DE4038203A1 (de) *	1990-11-30	1992-06-04	Kali Chemie Pharma Gmbh	Pharmazeutische spray-zubereitungen mit coronaraktiven wirkstoffen

1996
- 1996-04-12 US US08/630,064 patent/US5869082A/en not_active Expired - Lifetime
1997
- 1997-02-21 AT AT97907785T patent/ATE237322T1/de active
- 1997-02-21 EP EP97907785A patent/EP0927032B1/de not_active Expired - Lifetime
- 1997-02-21 DK DK97907785T patent/DK0927032T3/da active
- 1997-02-21 AU AU19693/97A patent/AU1969397A/en not_active Abandoned
- 1997-02-21 CA CA002251564A patent/CA2251564C/en not_active Expired - Lifetime
- 1997-02-21 WO PCT/US1997/002794 patent/WO1997038687A1/en not_active Ceased
- 1997-02-21 DE DE69721020T patent/DE69721020T2/de not_active Expired - Lifetime
- 1997-02-21 PT PT97907785T patent/PT927032E/pt unknown
- 1997-02-21 ES ES97907785T patent/ES2197990T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2251564A1 (en)	1997-10-23
WO1997038687A1 (en)	1997-10-23
ES2197990T3 (es)	2004-01-16
DE69721020D1 (de)	2003-05-22
DK0927032T3 (da)	2003-07-14
AU1969397A (en)	1997-11-07
CA2251564C (en)	2007-01-09
PT927032E (pt)	2003-07-31
EP0927032B1 (de)	2003-04-16
US5869082A (en)	1999-02-09
DE69721020T2 (de)	2003-12-04
EP0927032A1 (de)	1999-07-07

Legal Events

Date

Code

Title

Description

2003-12-15

UEP

Publication of translation of european patent specification

Ref document number: 0927032

Country of ref document: EP

Publication	Publication Date	Title
ATE237322T1 (de)	2003-05-15	Nichtpolares nitroglycerinspray zur bukkalen verabreichung
WO1997038663A3 (en)	1998-02-05	Buccal, non-polar spray or capsule
ATE288255T1 (de)	2005-02-15	Polares bukkales spray
WO2005030167A3 (en)	2006-04-13	Buccal, polar and non-polar spray containing alprazolam
NO963673L (no)	1996-09-03	Orale vehikkelblandinger
WO2004035021A3 (en)	2004-11-11	Buccal polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
DE69231992D1 (de)	2001-09-13	Fluorchlorkohlenwasserstofffreie Aerosolformulierungen
WO2004019912A3 (en)	2004-08-19	Buccal, polar or non-polar spray or capsule containing drugs for treating an infectious disease or cancer
HUP0002691A2 (hu)	2001-02-28	Ciklezonid tartalmú gyógyászati aeroszol termékek
WO2004043428A3 (en)	2004-10-21	Buccal, polar and non-polar spray or capsule containing drugs for treating pain
WO2004019911A3 (en)	2004-07-15	Buccal, polar or non-polar spray or capsule containing drugs for treating endocrine disorders
WO2004019909A3 (en)	2004-07-08	Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs
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