ATE237322T1 - Nichtpolares nitroglycerinspray zur bukkalen verabreichung - Google Patents
Nichtpolares nitroglycerinspray zur bukkalen verabreichungInfo
- Publication number
- ATE237322T1 ATE237322T1 AT97907785T AT97907785T ATE237322T1 AT E237322 T1 ATE237322 T1 AT E237322T1 AT 97907785 T AT97907785 T AT 97907785T AT 97907785 T AT97907785 T AT 97907785T AT E237322 T1 ATE237322 T1 AT E237322T1
- Authority
- AT
- Austria
- Prior art keywords
- polar
- nitroglycerin
- buccal administration
- nitroglycerin spray
- spray
- Prior art date
Links
- SNIOPGDIGTZGOP-UHFFFAOYSA-N Nitroglycerin Chemical compound [O-][N+](=O)OCC(O[N+]([O-])=O)CO[N+]([O-])=O SNIOPGDIGTZGOP-UHFFFAOYSA-N 0.000 title abstract 3
- 239000000006 Nitroglycerin Substances 0.000 title abstract 3
- 229960003711 glyceryl trinitrate Drugs 0.000 title abstract 3
- 239000000443 aerosol Substances 0.000 abstract 2
- 239000012454 non-polar solvent Substances 0.000 abstract 2
- 239000007921 spray Substances 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 235000013355 food flavoring agent Nutrition 0.000 abstract 1
- 210000002200 mouth mucosa Anatomy 0.000 abstract 1
- 239000003380 propellant Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Emergency Medicine (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/630,064 US5869082A (en) | 1996-04-12 | 1996-04-12 | Buccal, non-polar spray for nitroglycerin |
| PCT/US1997/002794 WO1997038687A1 (en) | 1996-04-12 | 1997-02-21 | Buccal, non-polar spray for nitroglycerin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE237322T1 true ATE237322T1 (de) | 2003-05-15 |
Family
ID=24525605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97907785T ATE237322T1 (de) | 1996-04-12 | 1997-02-21 | Nichtpolares nitroglycerinspray zur bukkalen verabreichung |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5869082A (de) |
| EP (1) | EP0927032B1 (de) |
| AT (1) | ATE237322T1 (de) |
| AU (1) | AU1969397A (de) |
| CA (1) | CA2251564C (de) |
| DE (1) | DE69721020T2 (de) |
| DK (1) | DK0927032T3 (de) |
| ES (1) | ES2197990T3 (de) |
| PT (1) | PT927032E (de) |
| WO (1) | WO1997038687A1 (de) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030190286A1 (en) * | 1997-10-01 | 2003-10-09 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating allergies or asthma |
| US20050287075A1 (en) * | 1997-10-01 | 2005-12-29 | Dugger Harry A Iii | Buccal, polar and non-polar spray or capsule containing drugs for treating pain |
| US20040136913A1 (en) * | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing sumatriptan |
| US20050002867A1 (en) * | 1997-10-01 | 2005-01-06 | Novadel Pharma Inc. | Buccal, polar and non-polar sprays containing propofol |
| AU4894697A (en) | 1997-10-01 | 1999-04-23 | Flemington Pharmaceutical Corporation | Buccal, polar and non-polar spray or capsule |
| US20030095926A1 (en) * | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the gastrointestinal tract or urinary tract |
| US20090162300A1 (en) * | 1997-10-01 | 2009-06-25 | Dugger Iii Harry A | Buccal, polar and non-polar spray containing alprazolam |
| US20030095925A1 (en) * | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders |
| US20040136914A1 (en) | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing ondansetron |
| US20050180923A1 (en) * | 1997-10-01 | 2005-08-18 | Dugger Harry A.Iii | Buccal, polar and non-polar spray containing testosterone |
| US20030077229A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs |
| US20030077228A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating endocrine disorders |
| US20040136915A1 (en) * | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing atropine |
| US20030082107A1 (en) * | 1997-10-01 | 2003-05-01 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer |
| US20050163719A1 (en) * | 1997-10-01 | 2005-07-28 | Dugger Harry A.Iii | Buccal, polar and non-polar spray containing diazepam |
| US20030095927A1 (en) * | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating muscular and skeletal disorders |
| US20030077227A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system |
| US7632517B2 (en) * | 1997-10-01 | 2009-12-15 | Novadel Pharma Inc. | Buccal, polar and non-polar spray containing zolpidem |
| US20040141923A1 (en) * | 1997-10-01 | 2004-07-22 | Dugger Harry A. | Buccal, polar and non-polar spray containing alprazolam |
| US20030185761A1 (en) * | 1997-10-01 | 2003-10-02 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating pain |
| US20050281752A1 (en) * | 1997-10-01 | 2005-12-22 | Dugger Harry A Iii | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system |
| US20030029208A1 (en) * | 2001-08-13 | 2003-02-13 | Ralph Merrem | Portable electronic device physical security |
| US20060073174A1 (en) * | 2001-08-16 | 2006-04-06 | Access Pharmaceuticals, Inc. | Adherent and erodible film to treat a moist surface of a body tissue |
| US6585997B2 (en) | 2001-08-16 | 2003-07-01 | Access Pharmaceuticals, Inc. | Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds |
| US7138133B2 (en) | 2001-10-10 | 2006-11-21 | The Procter & Gamble Company | Orally administered liquid compositions |
| WO2005004989A2 (en) * | 2003-07-01 | 2005-01-20 | Todd Maibach | Film comprising therapeutic agents |
| US7013685B2 (en) * | 2003-07-23 | 2006-03-21 | Acco Brands Usa Llc | Computer physical security device with retractable cable |
| KR20140104986A (ko) * | 2004-02-17 | 2014-08-29 | 트랜스셉트 파마슈티칼스, 인코포레이티드 | 구강 점막을 가로지르는 수면제 전달용 조성물 및 이의 사용 방법 |
| EP2767163A1 (de) | 2005-02-17 | 2014-08-20 | Abbott Laboratories | Transmukosale Verabreichung von Arzneimittelzusammensetzungen zur Behandlung und Vorbeugung von Erkrankungen bei Tieren |
| US20070225322A1 (en) * | 2005-05-25 | 2007-09-27 | Transoral Pharmaceuticals, Inc. | Compositions and methods for treating middle-of-the night insomnia |
| WO2006128022A2 (en) * | 2005-05-25 | 2006-11-30 | Transcept Pharmaceuticals, Inc. | Solid compositions and methods for treating middle-of-the night insomnia |
| US20070287740A1 (en) * | 2005-05-25 | 2007-12-13 | Transcept Pharmaceuticals, Inc. | Compositions and methods of treating middle-of-the night insomnia |
| EP2015632B1 (de) * | 2006-04-19 | 2015-12-02 | Mist Pharmaceuticals, LLC | Stabile wässrig-alkoholische mundsprayformulierungen und verfahren |
| JP2010513525A (ja) * | 2006-12-22 | 2010-04-30 | ノヴァデル ファーマ インコーポレイテッド | 安定な抗嘔吐経口噴霧製剤および方法 |
| EP2112923A1 (de) | 2007-01-22 | 2009-11-04 | Targacept Inc. | Intranasale, orale und sublinguale verabreichung von metanikotin-analogen |
| US20100215774A1 (en) * | 2007-02-09 | 2010-08-26 | Todd Maibach | Film comprising nitroglycerin |
| JP2010526837A (ja) * | 2007-05-10 | 2010-08-05 | ノヴァデル ファーマ インコーポレイテッド | 抗不眠症組成物および方法 |
| US20090004254A1 (en) * | 2007-06-19 | 2009-01-01 | Todd Maibach | Film comprising active drugs |
| US7985325B2 (en) * | 2007-10-30 | 2011-07-26 | Novellus Systems, Inc. | Closed contact electroplating cup assembly |
| DE202008007318U1 (de) | 2008-03-14 | 2008-07-31 | G. Pohl-Boskamp Gmbh & Co. Kg | Langzeitstabile pharmazeutische Zubereitung mit dem Wirkstoff Glyceroltrinitrat |
| DE202008008079U1 (de) * | 2008-06-16 | 2008-09-04 | G. Pohl-Boskamp Gmbh & Co. Kg | Pharmazeutische Zubereitung in Wasserdampf durchlässigen Behältern mit verbesserter Stabilität |
| CN102770152B (zh) | 2009-11-25 | 2016-07-06 | 阿瑞斯根股份有限公司 | 肽类的粘膜递送 |
| EP2600837A1 (de) | 2010-08-03 | 2013-06-12 | G. Pohl-Boskamp GmbH & Co. KG | Verwendung von glyceryltrinitrat zur behandlung von hämatomen |
| CA2827714A1 (en) | 2011-02-25 | 2012-08-30 | G. Pohl-Boskamp Gmbh & Co. Kg | Packaging of solid pharmaceutical preparations containing the active substance glyceryl trinitrate |
| EP2526971A1 (de) | 2011-05-25 | 2012-11-28 | ArisGen SA | Mukosale Freisetzung von Arzneimitteln |
| EP2668947B1 (de) | 2012-05-31 | 2016-11-30 | G. Pohl-Boskamp GmbH & Co. KG | Arteriogeneseinduktion mit einem stickstoffmonoxid-donor, z.b. nitroglycerin |
| US9248099B2 (en) | 2012-05-31 | 2016-02-02 | Desmoid Aktiengesellschaft | Use of stabilized granules containing glyceryl trinitrate for arteriogenesis |
| EP2878310B1 (de) | 2013-11-29 | 2017-01-11 | G. Pohl-Boskamp GmbH & Co. KG | Sprühbare wässrige Zusammensetzung mit Nitroglycerin |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE632504A (de) * | 1962-05-24 | |||
| DE3246081A1 (de) * | 1982-12-13 | 1984-06-14 | G. Pohl-Boskamp GmbH & Co Chemisch-pharmazeutische Fabrik, 2214 Hohenlockstedt | Nitroglycerin-spray |
| DE4007705C1 (de) * | 1990-03-10 | 1991-09-26 | G. Pohl-Boskamp Gmbh & Co. Chemisch-Pharmazeutische Fabrik, 2214 Hohenlockstedt, De | |
| WO1991016929A1 (en) * | 1990-05-10 | 1991-11-14 | Novo Nordisk A/S | A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols |
| DE4038203A1 (de) * | 1990-11-30 | 1992-06-04 | Kali Chemie Pharma Gmbh | Pharmazeutische spray-zubereitungen mit coronaraktiven wirkstoffen |
-
1996
- 1996-04-12 US US08/630,064 patent/US5869082A/en not_active Expired - Lifetime
-
1997
- 1997-02-21 ES ES97907785T patent/ES2197990T3/es not_active Expired - Lifetime
- 1997-02-21 PT PT97907785T patent/PT927032E/pt unknown
- 1997-02-21 EP EP97907785A patent/EP0927032B1/de not_active Expired - Lifetime
- 1997-02-21 AU AU19693/97A patent/AU1969397A/en not_active Abandoned
- 1997-02-21 WO PCT/US1997/002794 patent/WO1997038687A1/en not_active Ceased
- 1997-02-21 DE DE69721020T patent/DE69721020T2/de not_active Expired - Lifetime
- 1997-02-21 DK DK97907785T patent/DK0927032T3/da active
- 1997-02-21 AT AT97907785T patent/ATE237322T1/de active
- 1997-02-21 CA CA002251564A patent/CA2251564C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997038687A1 (en) | 1997-10-23 |
| EP0927032B1 (de) | 2003-04-16 |
| ES2197990T3 (es) | 2004-01-16 |
| DE69721020T2 (de) | 2003-12-04 |
| CA2251564A1 (en) | 1997-10-23 |
| DK0927032T3 (da) | 2003-07-14 |
| DE69721020D1 (de) | 2003-05-22 |
| US5869082A (en) | 1999-02-09 |
| EP0927032A1 (de) | 1999-07-07 |
| CA2251564C (en) | 2007-01-09 |
| PT927032E (pt) | 2003-07-31 |
| AU1969397A (en) | 1997-11-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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