ATE237592T1 - Akridinium derivate und deren konjugate - Google Patents

Akridinium derivate und deren konjugate

Info

Publication number
ATE237592T1
ATE237592T1 AT94101664T AT94101664T ATE237592T1 AT E237592 T1 ATE237592 T1 AT E237592T1 AT 94101664 T AT94101664 T AT 94101664T AT 94101664 T AT94101664 T AT 94101664T AT E237592 T1 ATE237592 T1 AT E237592T1
Authority
AT
Austria
Prior art keywords
group
specific binding
acridinium compounds
activity
conjugates
Prior art date
Application number
AT94101664T
Other languages
English (en)
Inventor
Naofumi Sato
Hiroshi Mochizuki
Toshinori Kanamori
Original Assignee
Mochida Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharm Co Ltd filed Critical Mochida Pharm Co Ltd
Application granted granted Critical
Publication of ATE237592T1 publication Critical patent/ATE237592T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
AT94101664T 1993-02-04 1994-02-03 Akridinium derivate und deren konjugate ATE237592T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP01746593A JP3584379B2 (ja) 1993-02-04 1993-02-04 アクリジニウム化合物およびアクリジニウム化合物複合体

Publications (1)

Publication Number Publication Date
ATE237592T1 true ATE237592T1 (de) 2003-05-15

Family

ID=11944776

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94101664T ATE237592T1 (de) 1993-02-04 1994-02-03 Akridinium derivate und deren konjugate

Country Status (7)

Country Link
US (2) US5438139A (de)
EP (1) EP0609885B1 (de)
JP (1) JP3584379B2 (de)
AT (1) ATE237592T1 (de)
CA (1) CA2114754A1 (de)
DE (1) DE69432497T2 (de)
ES (1) ES2196012T3 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7122671B1 (en) * 1979-07-19 2006-10-17 University College Cardiff Consultants Limited Luminescent labelling materials and procedures
US6414152B1 (en) * 1981-12-11 2002-07-02 University Of Wales College Of Medicine Of Heath Park Luminescent labelling material and procedures
DE3750503T2 (de) * 1986-10-22 1995-02-09 Abbott Lab Chemilumineszierende Acridinium- und Phenantridiniumsalze.
US5656426A (en) * 1988-08-01 1997-08-12 Chiron Diagnostics Corporation Functionaized hydrophilic acridinium esters
US5593845A (en) * 1993-05-17 1997-01-14 Lumigen, Inc. Aryl N-alkylacridancarboxylate derivatives useful for chemiluminescent detection
GB2282222A (en) * 1993-09-09 1995-03-29 Univ Nottingham Detecting genetic material using labelled DNA
GB2289334B (en) * 1994-05-10 1998-08-26 Molecular Light Technology Lim Enzyme linked chemiluminescent assay
US5731148A (en) * 1995-06-07 1998-03-24 Gen-Probe Incorporated Adduct protection assay
EP0761652A1 (de) * 1995-08-01 1997-03-12 Mochida Pharmaceutical Co., Ltd. Acridiniumverbindung mit mehreren lumineszierenden Gruppen und Bindungsgruppen und Konjugate derselben
US6165800A (en) * 1997-05-30 2000-12-26 Bayer Corporation Chemiluminescent energy transfer conjugates and their uses as labels in binding assays
JP4838932B2 (ja) * 1997-08-21 2011-12-14 メイン メディカル センター 過酸化物に基づく化学発光の検量方法、並びにそのために用いる化合物
JP4672144B2 (ja) 1998-08-11 2011-04-20 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッド 近赤外化学発光性アクリジニウム化合物およびその使用。
US6673560B1 (en) 1998-11-25 2004-01-06 Bayer Corporation Measurement of hydride using chemiluminescent acridinium compounds and applications thereof
US6723851B2 (en) 2001-10-31 2004-04-20 Quest Diagnostics Investment Incorporated Chemiluminescent compounds and use thereof
GB0320236D0 (en) * 2003-08-29 2003-10-01 Molecular Light Tech Res Ltd Chemiluminescent compounds
ES2392900T3 (es) * 2006-10-13 2012-12-14 Siemens Healthcare Diagnostics Inc. Ésteres de acridinio estables con emisión de luz rápida
US8293908B2 (en) * 2007-11-20 2012-10-23 Siemens Healthcare Diagnostics Inc. Facile N-alkylation of acridine compounds in ionic liquids
WO2021023252A1 (en) 2019-08-07 2021-02-11 Bgi Shenzhen Co., Ltd. Acridinium ester-containing compounds and methods of using the same for chemiluminescence-based one-color sequencing

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110932A (en) * 1986-10-06 1992-05-05 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
US4918192A (en) * 1986-10-06 1990-04-17 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
US4745181A (en) * 1986-10-06 1988-05-17 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
US5151518A (en) * 1987-10-02 1992-09-29 Abbott Laboratories N-arylation of isatins
NL8703075A (nl) * 1987-12-18 1989-07-17 Nederlanden Staat Acridiniumverbindingen als chemiluminescentie-merkstof.
US5290936A (en) * 1987-12-31 1994-03-01 London Diagnostics, Inc. Nitro substituted chemiluminescent labels and their conjugates, and assays therefrom
NZ227506A (en) * 1987-12-31 1992-06-25 London Diagnostics Inc Specific binding assays using chemiluminescent compounds
US5321136A (en) * 1987-12-31 1994-06-14 London Diagnostics, Inc. Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom
US4950613A (en) * 1988-02-26 1990-08-21 Gen-Probe Incorporated Proteted chemiluminescent labels
US5227489A (en) * 1988-08-01 1993-07-13 Ciba Corning Diagnostics Corp. Stable hydrophilic acridinium esters suitable for liposome encapsulation
US5241070A (en) * 1988-09-26 1993-08-31 Ciba Corning Diagnostics Corp. Nucleophilic polysubstituted aryl acridinium esters and uses thereof

Also Published As

Publication number Publication date
JPH06228102A (ja) 1994-08-16
US5438139A (en) 1995-08-01
DE69432497D1 (de) 2003-05-22
CA2114754A1 (en) 1994-08-05
DE69432497T2 (de) 2003-10-30
US5594112A (en) 1997-01-14
ES2196012T3 (es) 2003-12-16
EP0609885B1 (de) 2003-04-16
EP0609885A1 (de) 1994-08-10
JP3584379B2 (ja) 2004-11-04

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