ATE238549T1 - Phosphatase-aktivierte quervernetzende konjugierende und reduzierende agenzien, verfahren unter verwendung solcher agenzien und reagenzien die phosphatase-aktivierte quervernetzende und konjugierende agenzien enthalten - Google Patents

Phosphatase-aktivierte quervernetzende konjugierende und reduzierende agenzien, verfahren unter verwendung solcher agenzien und reagenzien die phosphatase-aktivierte quervernetzende und konjugierende agenzien enthalten

Info

Publication number
ATE238549T1
ATE238549T1 AT95943631T AT95943631T ATE238549T1 AT E238549 T1 ATE238549 T1 AT E238549T1 AT 95943631 T AT95943631 T AT 95943631T AT 95943631 T AT95943631 T AT 95943631T AT E238549 T1 ATE238549 T1 AT E238549T1
Authority
AT
Austria
Prior art keywords
agents
conjugating
linking
phosphatase
activated cross
Prior art date
Application number
AT95943631T
Other languages
English (en)
Inventor
Christopher Bieniarz
Mazhar Husain
Douglas F Young
Zbigniew Skrzypczynski
Michael J Cornwell
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE238549T1 publication Critical patent/ATE238549T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
    • C07F9/165—Esters of thiophosphoric acids
    • C07F9/1651—Esters of thiophosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
    • C07F9/165—Esters of thiophosphoric acids
    • C07F9/1652—Polyol derivatives esterified at least twice by thiophosphoric acid groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5537—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom the heteroring containing the structure -C(=O)-N-C(=O)- (both carbon atoms belong to the heteroring)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/811—Peptides or proteins is immobilized on, or in, an inorganic carrier
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
    • Y10S530/816—Attached to the carrier via a bridging agent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
AT95943631T 1994-12-02 1995-11-30 Phosphatase-aktivierte quervernetzende konjugierende und reduzierende agenzien, verfahren unter verwendung solcher agenzien und reagenzien die phosphatase-aktivierte quervernetzende und konjugierende agenzien enthalten ATE238549T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/349,167 US5736624A (en) 1994-12-02 1994-12-02 Phosphatase activated crosslinking, conjugating and reducing agents; methods of using such agents; and reagents comprising phosphatase activated crosslinking and conjugating agents
PCT/US1995/015586 WO1996017580A2 (en) 1994-12-02 1995-11-30 Phosphatase activated crosslinking, conjugating and reducing agents; methods of using such agents; and reagents comprising phosphatase activated crosslinking and conjugating agents

Publications (1)

Publication Number Publication Date
ATE238549T1 true ATE238549T1 (de) 2003-05-15

Family

ID=23371180

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95943631T ATE238549T1 (de) 1994-12-02 1995-11-30 Phosphatase-aktivierte quervernetzende konjugierende und reduzierende agenzien, verfahren unter verwendung solcher agenzien und reagenzien die phosphatase-aktivierte quervernetzende und konjugierende agenzien enthalten

Country Status (7)

Country Link
US (4) US5736624A (de)
EP (1) EP0795128B1 (de)
JP (1) JPH10509731A (de)
AT (1) ATE238549T1 (de)
DE (1) DE69530512T2 (de)
ES (1) ES2197214T3 (de)
WO (1) WO1996017580A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6617100B2 (en) 1998-09-25 2003-09-09 V.I. Technologies, Inc. Solid phase quenching systems
US6403359B1 (en) 1998-09-25 2002-06-11 V. I. TECHNOLOGIES, Inc. Solid phase quenching systems
US6703007B2 (en) * 1999-01-08 2004-03-09 The Procter & Gamble Company Topical compositions comprising functional nucleophiles protected by phosphorus-containing moieties
US6544499B1 (en) 1999-01-08 2003-04-08 The Procter & Gamble Company Topical compositions comprising protected functional thiols
GB0002626D0 (en) 2000-02-05 2000-03-29 Eastman Kodak Co Nonionic oligomeric surfactants and their use as dispersants and stabilisers
US6995248B2 (en) * 2001-07-16 2006-02-07 Dr. Chip Biotechnology, Inc. Immobilization of nucleic acids
US20030198966A1 (en) * 2002-04-19 2003-10-23 Stojanovic Milan N. Displacement assay for detection of small molecules
US7470516B2 (en) * 2003-04-14 2008-12-30 The Trustees Of Columbia University In The City Of New York Cross reactive arrays of three-way junction sensors for steroid determination
US20040203007A1 (en) * 2003-04-14 2004-10-14 Stojanovic Milan N. Cross reactive arrays of three-way junction sensors for steroid determination
US7351591B2 (en) * 2004-03-30 2008-04-01 Intel Corporation Surface modification of metals for biomolecule detection using surface enhanced Raman scattering (SERS)
WO2006116742A2 (en) * 2005-04-28 2006-11-02 Ventana Medical Systems, Inc. Fluorescent nanoparticles conjugated to antibodies via a peg linker
WO2006116628A2 (en) * 2005-04-28 2006-11-02 Ventana Medical Systems, Inc. Enzymes conjugated to antiobodies via a peg heterobifuctional linker
ES2548518T3 (es) 2005-11-23 2015-10-19 Ventana Medical Systems, Inc. Conjugado molecular
US7749957B2 (en) * 2006-04-06 2010-07-06 E.I. Du Pont De Nemours And Company Clay-binding peptides and methods of use
US7754680B2 (en) * 2007-07-26 2010-07-13 E. I. Du Pont De Nemours And Company Peptides for binding calcium carbonates and methods of use
CN114100588B (zh) * 2020-08-31 2024-03-22 泉州师范学院 一种含氮功能基团超高交联吸附剂及其制备方法和血液灌流器

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1023287A (en) * 1972-12-08 1977-12-27 Boehringer Mannheim G.M.B.H. Process for the preparation of carrier-bound proteins
US4166105A (en) * 1973-07-30 1979-08-28 Block Engineering, Inc. Dye tagged reagent
US4169137A (en) * 1974-12-20 1979-09-25 Block Engineering, Inc. Antigen detecting reagents
SE427505B (sv) * 1977-03-04 1983-04-11 Pharmacia Diagnostics Ab Reagens till anvendning vid immunkemiska bestemningsmetoder
US4652524A (en) * 1980-10-02 1987-03-24 Ivan E. Modrovich Soluble stabilized enzymes
US4520110A (en) * 1981-10-06 1985-05-28 The Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing a phycobiliprotein labeled ligand or receptor
US4542104A (en) * 1983-04-06 1985-09-17 The Board Of Trustees Of The Leland Stanford Jr. Univ. Phycobiliprotein fluorescent conjugates
US4657853A (en) * 1984-09-14 1987-04-14 E. I. Du Pont De Nemours And Company Immunoassays utilizing covalent conjugates of polymerized enzyme and antibody
US4970074A (en) * 1987-06-29 1990-11-13 Abbott Laboratories Fluorophores for encapsulation into liposomes
US4994385A (en) * 1987-10-30 1991-02-19 Abbott Laboratories Heterobifunctional coupling agents
US4843126A (en) * 1987-12-30 1989-06-27 The Lubrizol Corporation Aminoplast catalyst and compositions
US5053520A (en) * 1988-09-22 1991-10-01 Abbott Laboratories Heterobifunctional maleimido containing coupling agents
DK589389D0 (da) * 1989-11-23 1989-11-23 Novo Nordisk As Immobiliseret enzympraeparat
US5376403A (en) * 1990-02-09 1994-12-27 Capote; Miguel A. Electrically conductive compositions and methods for the preparation and use thereof
CA2073511A1 (en) * 1990-11-14 1992-05-29 Matthew R. Callstrom Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins
US5191066A (en) * 1990-12-07 1993-03-02 Abbott Laboratories Site-specific conjugation of immunoglobulins and detectable labels
JP3125428B2 (ja) * 1991-03-28 2001-01-15 和光純薬工業株式会社 修飾酵素
US5232484A (en) * 1991-08-13 1993-08-03 The Connecticut Agricultural Experiment Station Degradation of pesticides by ferric reagents and peroxide in the presence of light
CA2091544A1 (en) * 1992-03-26 1993-09-27 Shing F. Kwan Stabilization of functional proteins
US5674514A (en) * 1992-09-21 1997-10-07 Ciba-Geigy Corporation Storage stable pesticidal aqueous emulsions
WO1995002422A1 (en) * 1993-07-12 1995-01-26 Weltman Joel K Method for conjugating nucleotides and nucleosides to disulfide-, maleimide-, and thiol-containing compounds
US5571937A (en) * 1994-05-13 1996-11-05 Sloan-Kettering Institute For Cancer Research Complementary DNA and toxins

Also Published As

Publication number Publication date
JPH10509731A (ja) 1998-09-22
WO1996017580A2 (en) 1996-06-13
ES2197214T3 (es) 2004-01-01
WO1996017580A3 (en) 1996-10-10
US5789219A (en) 1998-08-04
EP0795128A2 (de) 1997-09-17
US6057429A (en) 2000-05-02
DE69530512D1 (de) 2003-05-28
US5736624A (en) 1998-04-07
DE69530512T2 (de) 2004-03-25
US6160153A (en) 2000-12-12
EP0795128B1 (de) 2003-04-23

Similar Documents

Publication Publication Date Title
ATE238549T1 (de) Phosphatase-aktivierte quervernetzende konjugierende und reduzierende agenzien, verfahren unter verwendung solcher agenzien und reagenzien die phosphatase-aktivierte quervernetzende und konjugierende agenzien enthalten
TW369617B (en) Plastic articles for medical use
BR9307444A (pt) Composição polimérica óleo lubrificante concentrado e processo para a preparação da composição polimérica
KR900006277A (ko) 시아나토 에스테르, 그의 경화성 수지 및 이로부터 제조된 물품
KR970006328A (ko) 올레핀중합촉매, 올레핀중합체의 제조방법 및 올레핀중합체
ES2128632T3 (es) Composiciones de revestimiento curables que contienen resina de carbamato y aditivos.
AU8383991A (en) Self-extinguishing polymeric compositions
WO2001040319A3 (en) Inhibition of polymerization of unsaturated monomers
TW367335B (en) Cyclo-olefin polymers and preparation process thereof
EP0947856A3 (de) Material für Okularlinse
KR927003488A (ko) 술폰화제 및 술폰화법
KR910016775A (ko) 방향족비닐화합물 중합용촉매 및 방향족비닐화합물 중합체의 제조방법
MX9605939A (es) Poliorganosiloxanos que contienen hidroxifenilo.
AU2003247597A1 (en) Antistatic agents and polymer compositions derived therefrom
KR890005569A (ko) 유기금속-함유 고분자 및 이들의 용도
WO2001055226A3 (fr) Dispersions aqueuses salines de (co)polymeres hydrosolubles a base de monomeres cationiques, leur procede de fabrication et leurs applications
ATE155148T1 (de) Höheres alpha-olefincopolymerisat, verfahren zu seiner herstellung, daraus hergestelltes vulkanisiertes produkt und vulkanisierbare gummizusammensetzung
JPS6445431A (en) Polyolefinic succineimide polyaminealkylacetoacetate adduct dispersion
KR910006212A (ko) 말단위치에 에틸렌적으로 불포화된 화합물 및 비선형광학분야에 이들을 사용하는 방법
EP0508623A3 (de) Persäuren
ATE103965T1 (de) Treibstoffadditivzusammensetzung.
EP0828167A3 (de) Harzzusammensetzung für Giesspolymerisation und optischer Gegenstand
BR9900760A (pt) Compostos silóxi assimétricos.
JPS6466214A (en) Production of alpha-olefin polymer
EP0945456A3 (de) Asymetrische Siloxyverbindungen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0795128

Country of ref document: EP

REN Ceased due to non-payment of the annual fee