ATE238777T1 - Transdermal patch enthaltend eine kombination von zwei oder mehr fettalkohole oder fettsäure als hautpenetrationbeschleuniger, ein klebrigmacher und ein haftmittel zur verbesserung der hafteigenschaften - Google Patents

Transdermal patch enthaltend eine kombination von zwei oder mehr fettalkohole oder fettsäure als hautpenetrationbeschleuniger, ein klebrigmacher und ein haftmittel zur verbesserung der hafteigenschaften

Info

Publication number
ATE238777T1
ATE238777T1 AT98117469T AT98117469T ATE238777T1 AT E238777 T1 ATE238777 T1 AT E238777T1 AT 98117469 T AT98117469 T AT 98117469T AT 98117469 T AT98117469 T AT 98117469T AT E238777 T1 ATE238777 T1 AT E238777T1
Authority
AT
Austria
Prior art keywords
adhesive
sticker
combination
transdermal patch
skin penetration
Prior art date
Application number
AT98117469T
Other languages
English (en)
Inventor
Dario Carrara
Original Assignee
Permatec Tech Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Permatec Tech Ag filed Critical Permatec Tech Ag
Application granted granted Critical
Publication of ATE238777T1 publication Critical patent/ATE238777T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98117469T 1997-09-17 1998-09-15 Transdermal patch enthaltend eine kombination von zwei oder mehr fettalkohole oder fettsäure als hautpenetrationbeschleuniger, ein klebrigmacher und ein haftmittel zur verbesserung der hafteigenschaften ATE238777T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI002106A IT1294748B1 (it) 1997-09-17 1997-09-17 Formulazione per un dispositivo transdermico

Publications (1)

Publication Number Publication Date
ATE238777T1 true ATE238777T1 (de) 2003-05-15

Family

ID=11377881

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98117469T ATE238777T1 (de) 1997-09-17 1998-09-15 Transdermal patch enthaltend eine kombination von zwei oder mehr fettalkohole oder fettsäure als hautpenetrationbeschleuniger, ein klebrigmacher und ein haftmittel zur verbesserung der hafteigenschaften

Country Status (14)

Country Link
US (1) US6231885B1 (de)
EP (1) EP0913158B1 (de)
JP (1) JPH11152224A (de)
KR (1) KR19990029891A (de)
AR (1) AR019001A1 (de)
AT (1) ATE238777T1 (de)
AU (1) AU742399B2 (de)
CA (1) CA2247767A1 (de)
DE (1) DE69813988D1 (de)
IL (1) IL126267A0 (de)
IT (1) IT1294748B1 (de)
NZ (1) NZ331904A (de)
TW (1) TW493994B (de)
ZA (1) ZA988421B (de)

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN814496A0 (en) * 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
DE19828274C2 (de) * 1998-06-25 2002-11-28 Rottapharm Bv Transdermales therapeutisches System, enthaltend Hormone und Kristallisationsinhibitoren
US20020160995A1 (en) * 1998-08-03 2002-10-31 Easterling W. Jerry Medication and method for remediating existing scars through transdermal, topical delivery of calcium channel blockers
WO2000074661A2 (en) * 1999-06-05 2000-12-14 Noven Pharmaceuticals, Inc. Solubility enhancement of drugs in transdermal drug delivery systems and methods of use
DE19950066A1 (de) * 1999-10-16 2001-04-26 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit einem Gehalt an Tulobuterol-hydrochlorid zur Verabreichung des Bronchodilatators Tulobuterol über die Haut
AU3104301A (en) 2000-01-20 2001-07-31 Noven Pharmaceuticals, Inc. Compositions and methods to effect the release profile in the transdermal administration of active agents
DE10015783C2 (de) * 2000-03-30 2003-12-04 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur Abgabe von Lerisetron und seine Verwendung
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
US20020119187A1 (en) * 2000-09-29 2002-08-29 Cantor Adam S. Composition for the transdermal delivery of fentanyl
AUPR549901A0 (en) * 2001-06-06 2001-07-12 Vital Health Sciences Pty Ltd Topical formulation containing tocopheryl phosphates
KR20020037616A (ko) * 2000-11-15 2002-05-22 서경배 케토롤락의 경피흡수제제
AU2002235155A1 (en) * 2000-12-05 2002-06-18 Noven Pharmaceuticals, Inc. Crystallization inhibition of drugs in transdermal drug delivery systems
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
ES2559666T3 (es) 2001-03-07 2016-02-15 Hisamitsu Pharmaceutical Co., Inc. Parche adhesivo
US20040170672A1 (en) * 2001-03-07 2004-09-02 Thorsten Selzer Transdermal therapeutic system for administration of partial dopamine-d2 agonists
US20050208117A1 (en) * 2001-03-16 2005-09-22 Venkatraman Subramanian S Transdermal administration of fentanyl and analogs thereof
ES2270746T3 (es) * 2001-03-16 2007-12-01 Alza Corporation Parche transdermico para administrar fentanilo.
DE10114382A1 (de) * 2001-03-23 2002-09-26 Beiersdorf Ag Feuchtigkeitsaufnehmende Matrix auf Silikonbasis insbesondere zur Wundversorgung und/oder pharmazeutisch/kosmetischen Hautbehandlung
EP1390084B1 (de) * 2001-05-01 2011-03-23 A.V. Topchiev Institute of Petrochemical Synthesis Zweiphasige, wasserabsorbierende bioadhäsive zusammenstezung
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
US8541021B2 (en) * 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
ES2331302T3 (es) 2001-05-01 2009-12-29 A.V. Topchiev Institute Of Petrochemical Synthesis Composiciones de hidrogel.
US20030018074A1 (en) * 2001-07-06 2003-01-23 Robert Kleiman Antiviral composition and treatment method
EP1421955A1 (de) * 2001-08-10 2004-05-26 Hisamitsu Pharmaceutical Co., Inc. Perkutane absorptionszubereitungen
CA2460352C (en) * 2001-08-17 2013-05-14 Lavipharm Laboratories Inc. Composition and transdermal drug delivery device
DE10159120B4 (de) * 2001-12-01 2006-08-17 Lts Lohmann Therapie-Systeme Ag Steroidhormonhaltige transdermale therapeutische Systeme enthaltend Propylenglycolmonocaprylat und seine Verwendung
US7921999B1 (en) 2001-12-20 2011-04-12 Watson Laboratories, Inc. Peelable pouch for transdermal patch and method for packaging
WO2003066130A2 (en) * 2002-02-07 2003-08-14 Massachusetts Institute Of Technology Transdermal drug delivery systems
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
WO2003074035A1 (de) * 2002-03-06 2003-09-12 Hexal Ag Transdermalsystem mit fentanyl
JP2005526839A (ja) * 2002-04-23 2005-09-08 アルザ・コーポレーシヨン 不正使用の可能性が低い経皮鎮痛薬システム
KR20050045946A (ko) 2002-06-25 2005-05-17 애크럭스 디디에스 피티와이 리미티드 비정질 약학적 조성물을 이용한 경피전달속도의 제어
AU2002950713A0 (en) 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
JP4354678B2 (ja) 2002-08-28 2009-10-28 久光製薬株式会社 貼付剤
US20040086551A1 (en) 2002-10-30 2004-05-06 Miller Kenneth J. Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl
CA2453013C (en) * 2002-12-13 2011-02-15 Gary W. Cleary Dermal, transdermal, mucosal or transmucosal ingredient delivery devices
DE10304988A1 (de) * 2003-02-07 2004-09-09 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System mit verbessertem Hautklebeverhalten
ES2335498T3 (es) 2003-03-10 2010-03-29 Nycomed Gmbh Nuevo proceso para la preparacion de reflumilast.
RS20050812A (sr) * 2003-04-30 2007-12-31 Purdue Pharma L.P., Transdermalni dozni oblik otporan na promene
US8790689B2 (en) 2003-04-30 2014-07-29 Purdue Pharma L.P. Tamper resistant transdermal dosage form
EP1648363B1 (de) * 2003-07-03 2019-03-06 Corium International, Inc. Wundverband, vorrichtung zur inhaltsstoffzuführung und iv-hold-down sowie verfahren im zusammenhang damit
TWI341735B (en) * 2003-07-31 2011-05-11 Hisamitsu Pharmaceutical Co Adhesive preparations
US20070059351A1 (en) * 2003-10-17 2007-03-15 Murrell George A C Transdermal patches containing a nitric oxide-donor and a second active agent and associated methods
US20060286159A1 (en) * 2003-10-17 2006-12-21 Calvert Murrell George A Treatment of persistent active tendinopathy using transdermal glyceryl trinitrate providing durability of effect
US20070053966A1 (en) * 2003-10-17 2007-03-08 Robert Ang Medicated orthopedic support structures for treatment of damaged musculoskeletal tissue
US20060286158A1 (en) * 2003-10-17 2006-12-21 Calvert Murrell George A Treatment of overuse tendinopathy using transdermal nitric oxide-generating agents
RU2380092C2 (ru) 2004-01-30 2010-01-27 Кориум Интернэшнл, Инк. Быстро растворяющаяся пленка для доставки активного агента
JP4847437B2 (ja) * 2004-03-03 2011-12-28 バイタル ヘルス サイエンシズ プロプライアタリー リミティド アルカロイド製剤
BRPI0513673B8 (pt) * 2004-08-03 2021-07-27 Vital Health Sciences Pty Ltd método para produzir um medicamento para aumentar a eficácia e o transporte dos compostos biologicamente ativos enteralmente administrados, e composição farmacêutica
EP1791575B1 (de) * 2004-08-05 2014-10-08 Corium International, Inc. Klebstoffzusammensetzung
ES2265239B1 (es) * 2004-09-23 2008-02-01 Laboratorio Reig Jofre, S.A. Composicion farmaceutica para administracion transdermica.
US8252319B2 (en) 2004-10-21 2012-08-28 Durect Corporation Transdermal delivery system for sufentanil
SI1814531T1 (sl) 2004-10-21 2010-10-29 Durect Corp Transdermalni dostavni sistem
US20060188558A1 (en) * 2005-02-18 2006-08-24 Mylan Technologies, Inc. Transdermal systems having control delivery system
US20090239827A1 (en) * 2005-03-03 2009-09-24 Esra Ogru Compounds having lipid lowering properties
US8663694B2 (en) * 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
ITMI20050477A1 (it) * 2005-03-23 2006-09-24 Bouty S P A Cerotto transdermico
US9168216B2 (en) 2005-06-17 2015-10-27 Vital Health Sciences Pty. Ltd. Carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
US20110086086A1 (en) * 2005-07-26 2011-04-14 Pfizer Inc Transdermal system for varenicline
US7884158B2 (en) * 2005-09-06 2011-02-08 L'Oré´al Cosmetic compositions containing block copolymers, tackifiers and phenylated silicones
US9056061B2 (en) * 2005-09-23 2015-06-16 Alza Corporation Transdermal nicotine salt delivery system
US8383149B2 (en) 2005-09-23 2013-02-26 Alza Corporation High enhancer-loading polyacrylate formulation for transdermal applications
WO2007035941A2 (en) * 2005-09-23 2007-03-29 Alza Corporation Transdermal galantamine delivery system
DE102005056393A1 (de) * 2005-11-24 2007-05-31 Grünenthal GmbH Multicyclische Verbindungen in druckempfindlichen Klebstoffen
US20070122699A1 (en) * 2005-11-30 2007-05-31 Rovcal, Inc. Electrochemical cells having improved gelling agents
US20070202155A1 (en) * 2006-02-03 2007-08-30 Cure Therapeutics, Inc. Low dose no donor-containing transdermal patch
US20070259026A1 (en) * 2006-04-20 2007-11-08 Robert Ang Vasodialating dressing for use with intravenous catheters
US20080152592A1 (en) * 2006-12-21 2008-06-26 Bayer Healthcare Llc Method of therapeutic drug monitoring
WO2008115224A2 (en) * 2007-03-20 2008-09-25 Bayer Healthcare Llc Method of analyzing an analyte
DE102007041557B4 (de) * 2007-08-29 2011-03-31 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System enthaltend längliche Hohlkörper
US8470360B2 (en) 2008-04-18 2013-06-25 Warsaw Orthopedic, Inc. Drug depots having different release profiles for reducing, preventing or treating pain and inflammation
MY154027A (en) * 2007-10-15 2015-04-30 Alza Corp Once-a-day replacement transdermal administration of fentanyl
DE102007060175A1 (de) * 2007-12-13 2009-06-18 Johannes Gutenberg-Universität Mainz Quartärnisierung des Zusatzstoffs Aminoalkyl Methacrylat Copolymer E zur Verbesserung der Permeabilität und Löslichkeit von Arzneistoffen
WO2009106831A2 (en) 2008-02-28 2009-09-03 Syntropharma Limited Pharmaceutical composition
US20090263456A1 (en) * 2008-04-18 2009-10-22 Warsaw Orthopedic, Inc. Methods and Compositions for Reducing Preventing and Treating Adhesives
WO2010083035A2 (en) 2009-01-14 2010-07-22 Corium International, Inc. Transdermal administration of tamsulosin
EP2506838A1 (de) * 2009-12-01 2012-10-10 Noven Pharmaceuticals, INC. Transdermale testosteronvorrichtung und freisetzung
EP2531047B1 (de) 2010-02-05 2024-11-13 Phosphagenics Limited Träger mit einem nichtneutralisierten tocopherylphosphat
ES2829386T3 (es) 2010-03-30 2021-05-31 Phosphagenics Ltd Parche de administración transdérmica
ES2608782T3 (es) 2010-04-30 2017-04-17 Teikoku Pharma Usa, Inc. Composiciones transdérmicas de propinilaminoindano
WO2012122586A1 (en) 2011-03-15 2012-09-20 Phosphagenics Limited New composition
EP2688561B1 (de) 2011-03-24 2018-08-22 Teikoku Pharma USA, Inc. Transdermale zusammensetzungen mit einer wirkstoffschicht und einer wirkstoffumwandlungsschicht
CN102895358A (zh) * 2011-07-29 2013-01-30 苏州知微堂生物科技有限公司 一种三黄汤整合型新剂型制备技术及其生产方法
PH12014501000A1 (en) * 2011-11-04 2014-06-09 Agile Therapeutics Inc Dermal delivery compositions and methods
JP5913614B2 (ja) 2011-11-09 2016-04-27 テイコク ファーマ ユーエスエー インコーポレーテッド 皮膚新生物の処置方法
AU2013338243B2 (en) 2012-11-02 2016-09-29 Teikoku Seiyaku Co., Ltd. Propynylaminoindan transdermal compositions
CA2949474C (en) 2014-05-28 2022-06-21 Teikoku Seiyaku Co., Ltd. Transdermal absorption preparation containing silodosin or tamsulosin
EP3169318B1 (de) 2014-07-18 2020-04-01 Buzzz Pharmaceuticals Limited Gegen missbrauch gesichertes transdermales system
US9789070B2 (en) 2015-07-28 2017-10-17 Elc Management Llc Sheet packs for treating facial or body surfaces
MX383940B (es) 2015-12-09 2025-03-14 Phosphagenics Ltd Formulación farmacéutica que contiene tocol fosfato.
WO2017131034A1 (ja) * 2016-01-28 2017-08-03 久光製薬株式会社 経皮吸収製剤
WO2018006069A1 (en) * 2016-06-30 2018-01-04 Teva Pharmaceuticals International Gmbh Improved formulations for transdermal pharmaceutical systems
IL267006B2 (en) 2016-12-21 2024-11-01 Phosphagenics Ltd Process for phosphorylation of a complex alcohol with p4o10 at high temperatures, and products thereof
US10406114B2 (en) * 2017-06-11 2019-09-10 Masoumeh Nasrollahzadeh Abyazani Antibiotic-loaded transdermal patch

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4626539A (en) * 1984-08-10 1986-12-02 E. I. Dupont De Nemours And Company Trandermal delivery of opioids
US4764381A (en) 1985-12-06 1988-08-16 Key Pharmaceuticals, Inc. Percutaneous penetration enhancer of oleic acid and 2-ethyl-1, 3-hexanediol
US4863970A (en) 1986-11-14 1989-09-05 Theratech, Inc. Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
US5023084A (en) 1986-12-29 1991-06-11 Rutgers, The State University Of New Jersey Transdermal estrogen/progestin dosage unit, system and process
US4788062A (en) 1987-02-26 1988-11-29 Alza Corporation Transdermal administration of progesterone, estradiol esters, and mixtures thereof
US4816258A (en) 1987-02-26 1989-03-28 Alza Corporation Transdermal contraceptive formulations
EP0394429B1 (de) 1988-10-27 1996-01-10 Schering Aktiengesellschaft Mittel zur transdermalen applikation enthaltend gestoden
IL92537A (en) 1988-12-15 1994-04-12 Riker Laboratories Inc Topical preparations and dermal systems containing 1-isobutyl-H1-imidazo [C-4,5] quinoline-4-amine
US4973468A (en) 1989-03-22 1990-11-27 Cygnus Research Corporation Skin permeation enhancer compositions
US5091186A (en) 1989-08-15 1992-02-25 Cygnus Therapeutic Systems Biphasic transdermal drug delivery device
SE8904296D0 (sv) 1989-12-21 1989-12-21 Pharmacia Ab Transdermal system
GB9021674D0 (en) 1990-10-05 1990-11-21 Ethical Pharma Ltd Transdermal device
US5225198A (en) 1991-08-27 1993-07-06 Cygnus Therapeutic Systems Transdermal administration of short or intermediate half-life benzodiazepines
US5229130A (en) * 1991-12-20 1993-07-20 Cygnus Therapeutics Systems Vegetable oil-based skin permeation enhancer compositions, and associated methods and systems
DE69326461T2 (de) 1992-06-11 2000-05-04 Theratech Inc., Salt Lake City Verwendung von glyzerin zur dämpfung der transdermalen arzneimittelverabreichung
WO1995001767A1 (en) 1993-07-08 1995-01-19 Cygnus Therapeutic Systems Monolithic matrix transdermal delivery system
US5466465A (en) 1993-12-30 1995-11-14 Harrogate Holdings, Limited Transdermal drug delivery system
AU2345695A (en) * 1994-04-28 1995-11-29 F. Hoffmann-La Roche Ag Pharmaceutical composition for transdermal delivery

Also Published As

Publication number Publication date
DE69813988D1 (de) 2003-06-05
EP0913158B1 (de) 2003-05-02
KR19990029891A (ko) 1999-04-26
IT1294748B1 (it) 1999-04-12
TW493994B (en) 2002-07-11
CA2247767A1 (en) 1999-03-17
AU8423098A (en) 1999-04-01
ITMI972106A1 (it) 1999-03-17
AU742399B2 (en) 2002-01-03
AR019001A1 (es) 2001-12-26
US6231885B1 (en) 2001-05-15
JPH11152224A (ja) 1999-06-08
NZ331904A (en) 1999-03-29
EP0913158A1 (de) 1999-05-06
IL126267A0 (en) 1999-05-09
ZA988421B (en) 1999-03-17

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