ATE239023T1 - Antiallergische imidazo(1,2-a)thieno(2,3- d)azepinderivate - Google Patents

Antiallergische imidazo(1,2-a)thieno(2,3- d)azepinderivate

Info

Publication number: ATE239023T1
Authority: AT; Austria
Prior art keywords: 4alkyl; hydroxycarbonyl; substituted; pct; represents hydrogen
Prior art date: 1992-12-04

Application number

AT94901887T

Other languages

English (en)

Inventor

Frans Eduard Janssens

Gaston Stanislas Marcell Diels

Joseph Elisabeth Leenaerts

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-12-04

Filing date

1993-11-25

Publication date

2003-05-15

1993-11-25 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2003-05-15 Application granted granted Critical

2003-05-15 Publication of ATE239023T1 publication Critical patent/ATE239023T1/de

Links

KKUXUPFZDZLZBB-UHFFFAOYSA-N 13-thia-4,7-diazatricyclo[8.3.0.03,7]trideca-1(10),2,4,8,11-pentaene Chemical class C1=CN2CC=NC2=CC2=C1C=CS2 KKUXUPFZDZLZBB-UHFFFAOYSA-N 0.000 title 1
230000003266 anti-allergic effect Effects 0.000 title 1
ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical group O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 5
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
150000002431 hydrogen Chemical group 0.000 abstract 3
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 2
125000001475 halogen functional group Chemical group 0.000 abstract 2
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
150000001538 azepines Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
-1 hydroxyC1-4alkyl Chemical group 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pulmonology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT94901887T 1992-12-04 1993-11-25 Antiallergische imidazo(1,2-a)thieno(2,3- d)azepinderivate ATE239023T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP92203778		1992-12-04
PCT/EP1993/003321 WO1994013680A1 (en)	1992-12-04	1993-11-25	ANTIALLERGIC IMIDAZO[1,2-a](PYRROLO, THIENO OR FURANO)[2,3-d]AZEPINE DERIVATIVES

Publications (1)

Publication Number	Publication Date
ATE239023T1 true ATE239023T1 (de)	2003-05-15

Family

ID=8211106

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94901887T ATE239023T1 (de)	1992-12-04	1993-11-25	Antiallergische imidazo(1,2-a)thieno(2,3- d)azepinderivate

Country Status (16)

Country	Link
US (1)	US5629308A (de)
EP (1)	EP0672047B1 (de)
JP (1)	JP3503064B2 (de)
KR (1)	KR100251295B1 (de)
AT (1)	ATE239023T1 (de)
AU (1)	AU676702B2 (de)
CA (1)	CA2150805C (de)
DE (1)	DE69332929T2 (de)
ES (1)	ES2199224T3 (de)
FI (1)	FI952723A7 (de)
HU (1)	HU223466B1 (de)
NO (1)	NO311523B1 (de)
NZ (1)	NZ258552A (de)
PL (1)	PL176235B1 (de)
RU (1)	RU2134269C1 (de)
WO (1)	WO1994013680A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2196020T3 (es) *	1992-12-04	2003-12-16	Janssen Pharmaceutica Nv	Derivados de triazolobenzazepina antialergicos.
NZ258553A (en) *	1992-12-04	1996-06-25	Janssen Pharmaceutica Nv	Azepine derivatives; compounds, process for preparation and pharmaceutical compositions containing such compounds
FR2735474B1 (fr) *	1995-06-13	1997-08-08	Roussel Uclaf	Chlorhydrate de zilpaterol sous une forme cristallisee particuliere, son procede de preparation et les produits intermediaires mis en oeuvre
TW527186B (en)	1996-03-19	2003-04-11	Janssen Pharmaceutica Nv	Fused imidazole derivatives as multidrug resistance modulators
AU1146099A (en) *	1997-09-18	1999-04-05	Janssen Pharmaceutica N.V.	Fused imidazole derivatives for improving oral bioavailability of pharmaceuticalagents
WO2002100862A2 (en)	2001-06-12	2002-12-19	Janssen Pharmaceutica N.V.	Novel substituted tetracyclic imidazole derivatives, processes for their preparation, pharmaceutical compositions comprising them and their use as a medicine
FR2872165B1 (fr) *	2004-06-24	2006-09-22	Sod Conseils Rech Applic	Nouveaux derives de pyrimido-benzimidazole
US8470812B2 (en) *	2009-12-30	2013-06-25	Arqule, Inc.	Substituted benzo-pyrimido-tetrazolo-diazepine compounds
BR112017003745A2 (pt)	2014-08-29	2017-12-05	Tes Pharma S R L	inibidores de semialdeído descarboxilase de ácido alfa-amino-beta-carboximucônico

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA755418B (en) *	1974-09-11	1977-06-29	Hoffmann La Roche	Diazepine derivatives
NZ180218A (en) *	1975-08-07	1983-07-15	Hoffmann La Roche	6-(phenyl or pyridyl)-4h-imidazo(1,5-a) (1,4) diazepines
FI880814A7 (fi) *	1987-03-10	1988-09-11	Hoffmann La Roche	Imidazodiazepin-derivat.
EP0552292B1 (de) *	1990-10-10	1995-06-21	Schering Corporation	Substituierte imidazobenzazepine und imidazopyridoazepine
IL101851A (en) *	1991-06-13	1996-05-14	Janssen Pharmaceutica Nv	10-(4-piperidinyl- and piperidinylidene)-imidazo [1,2-a] (pyrrolo thieno or furano) [2,3] azepine derivatives their preparation and pharmaceutical compositions containing them and certain novel intermediates therefor

1993
- 1993-11-25 CA CA002150805A patent/CA2150805C/en not_active Expired - Fee Related
- 1993-11-25 NZ NZ258552A patent/NZ258552A/en unknown
- 1993-11-25 PL PL93309254A patent/PL176235B1/pl not_active IP Right Cessation
- 1993-11-25 AU AU56279/94A patent/AU676702B2/en not_active Ceased
- 1993-11-25 JP JP51372194A patent/JP3503064B2/ja not_active Expired - Fee Related
- 1993-11-25 ES ES94901887T patent/ES2199224T3/es not_active Expired - Lifetime
- 1993-11-25 US US08/433,386 patent/US5629308A/en not_active Expired - Fee Related
- 1993-11-25 AT AT94901887T patent/ATE239023T1/de not_active IP Right Cessation
- 1993-11-25 DE DE69332929T patent/DE69332929T2/de not_active Expired - Fee Related
- 1993-11-25 KR KR1019950702171A patent/KR100251295B1/ko not_active Expired - Fee Related
- 1993-11-25 RU RU95114527A patent/RU2134269C1/ru not_active IP Right Cessation
- 1993-11-25 HU HU9501620A patent/HU223466B1/hu not_active IP Right Cessation
- 1993-11-25 WO PCT/EP1993/003321 patent/WO1994013680A1/en not_active Ceased
- 1993-11-25 EP EP94901887A patent/EP0672047B1/de not_active Expired - Lifetime
1995
- 1995-06-02 NO NO19952199A patent/NO311523B1/no unknown
- 1995-06-02 FI FI952723A patent/FI952723A7/fi unknown

Also Published As

Publication number	Publication date
CA2150805A1 (en)	1994-06-23
JP3503064B2 (ja)	2004-03-02
NO311523B1 (no)	2001-12-03
HUT71807A (en)	1996-02-28
WO1994013680A1 (en)	1994-06-23
AU5627994A (en)	1994-07-04
NO952199D0 (no)	1995-06-02
NO952199L (no)	1995-08-04
DE69332929T2 (de)	2004-02-26
PL176235B1 (pl)	1999-05-31
FI952723A0 (fi)	1995-06-02
FI952723A7 (fi)	1995-06-02
US5629308A (en)	1997-05-13
CA2150805C (en)	2006-08-15
KR100251295B1 (ko)	2000-05-01
JPH08503953A (ja)	1996-04-30
EP0672047A1 (de)	1995-09-20
NZ258552A (en)	1996-07-26
DE69332929D1 (de)	2003-06-05
EP0672047B1 (de)	2003-05-02
PL309254A1 (en)	1995-10-02
RU2134269C1 (ru)	1999-08-10
HU223466B1 (hu)	2004-07-28
ES2199224T3 (es)	2004-02-16
HU9501620D0 (en)	1995-08-28
RU95114527A (ru)	1997-06-10
AU676702B2 (en)	1997-03-20

Legal Events

Date	Code	Title	Description
2003-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
MX9202856A (es)	1992-12-01	Derivados de imidazo [1,2-b][3]benzoazepina, composiciones y metodo de uso.
GR3031500T3 (en)	2000-01-31	NOVEL 9-HYDROXY-PYRIDO [1,2-a]PYRIMIDIN-4-ONE ETHER DERIVATIVES
MX9202860A (es)	1992-12-01	Derivados de imidazo (1,2-a) (pirrolo, tieno o furano) (2,3-d) azepina, composiciones y metodos de uso.
DE69332929D1 (de)	2003-06-05	ANTIALLERGISCHE IMIDAZO[1,2-a]THIENO[2,3-d]AZEPINDERIVATE
GR3034495T3 (en)	2000-12-29	Antiallergic triazolo(pyrrolo, thieno or furano)azepine derivatives.