ATE240719T1 - Pharmazeutische tablette mit verzögerter freisetzung, enthaltend eine matrix aus quervernetzter amylose und hydroxypropyl methylzellulose - Google Patents

Pharmazeutische tablette mit verzögerter freisetzung, enthaltend eine matrix aus quervernetzter amylose und hydroxypropyl methylzellulose

Info

Publication number
ATE240719T1
ATE240719T1 AT97915220T AT97915220T ATE240719T1 AT E240719 T1 ATE240719 T1 AT E240719T1 AT 97915220 T AT97915220 T AT 97915220T AT 97915220 T AT97915220 T AT 97915220T AT E240719 T1 ATE240719 T1 AT E240719T1
Authority
AT
Austria
Prior art keywords
cross
linked amylose
tablet containing
matrix
methyl cellulose
Prior art date
Application number
AT97915220T
Other languages
English (en)
Inventor
Francois Chouinard
Wilfrid Jacques
Original Assignee
Labopharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labopharm Inc filed Critical Labopharm Inc
Application granted granted Critical
Publication of ATE240719T1 publication Critical patent/ATE240719T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT97915220T 1996-04-10 1997-04-04 Pharmazeutische tablette mit verzögerter freisetzung, enthaltend eine matrix aus quervernetzter amylose und hydroxypropyl methylzellulose ATE240719T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002173818A CA2173818A1 (fr) 1996-04-10 1996-04-10 Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose
PCT/CA1997/000229 WO1997037639A1 (fr) 1996-04-10 1997-04-04 Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose

Publications (1)

Publication Number Publication Date
ATE240719T1 true ATE240719T1 (de) 2003-06-15

Family

ID=4157953

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97915220T ATE240719T1 (de) 1996-04-10 1997-04-04 Pharmazeutische tablette mit verzögerter freisetzung, enthaltend eine matrix aus quervernetzter amylose und hydroxypropyl methylzellulose

Country Status (22)

Country Link
US (1) US5885615A (de)
EP (1) EP0954290B1 (de)
JP (1) JP4166278B2 (de)
KR (1) KR100439614B1 (de)
CN (1) CN1218396A (de)
AT (1) ATE240719T1 (de)
AU (1) AU711089B2 (de)
BR (1) BR9708772A (de)
CA (1) CA2173818A1 (de)
CZ (1) CZ294342B6 (de)
DE (1) DE69722247T2 (de)
DK (1) DK0954290T3 (de)
ES (1) ES2200166T3 (de)
IL (1) IL126477A (de)
MY (1) MY115535A (de)
NO (1) NO321862B1 (de)
NZ (1) NZ332576A (de)
PL (1) PL187764B1 (de)
PT (1) PT954290E (de)
TR (1) TR199802034T2 (de)
WO (1) WO1997037639A1 (de)
ZA (1) ZA973054B (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ260408A (en) 1993-05-10 1996-05-28 Euro Celtique Sa Controlled release preparation comprising tramadol
US6197339B1 (en) 1997-09-30 2001-03-06 Pharmacia & Upjohn Company Sustained release tablet formulation to treat Parkinson's disease
US6284273B1 (en) * 1998-02-24 2001-09-04 Vincent Lenaerts Cross-linked high amylose starch resistant to amylase as a matrix for the slow release of biologically active compounds
WO2000033818A1 (en) 1998-12-11 2000-06-15 Nostrum Pharmaceuticals, Inc. Sustained release tablet containing hydrocolloid and cellulose ether
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
EP1174127A1 (de) * 2000-07-21 2002-01-23 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Zuammensetzung zur zielgesteuerten Freigabe eines Wirkstoffs und Verfahren zur Herstellung einer solchen Zusammensetzung
WO2003017981A1 (en) * 2001-08-29 2003-03-06 Ranbaxy Laboratories Limited Controlled release formulation of clarithromycin or tinidazol
CA2479350A1 (en) * 2002-03-15 2003-09-25 Cypress Bioscience, Inc. Ne and 5-ht reuptake inhibitors for treating visceral pain syndromes
DK1558935T3 (da) * 2002-10-25 2008-11-17 Labopharm Inc Præparater med styret afgivelse
MY142195A (en) * 2002-10-25 2010-10-15 Labopharm Inc Controlled-release compositions
US8487002B2 (en) * 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
US20040132826A1 (en) * 2002-10-25 2004-07-08 Collegium Pharmaceutical, Inc. Modified release compositions of milnacipran
TWI319713B (en) * 2002-10-25 2010-01-21 Sustained-release tramadol formulations with 24-hour efficacy
US20060003004A1 (en) * 2002-10-25 2006-01-05 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
WO2004047651A2 (en) * 2002-11-25 2004-06-10 Boston Scientific Limited Injection device for treating mammalian body
JP2006515008A (ja) * 2003-01-28 2006-05-18 コレギウム ファーマシューティカル， インコーポレイテッド 経口投与のためのミルナシプランの多粒子状組成物
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
AR051654A1 (es) * 2004-11-04 2007-01-31 Astrazeneca Ab Nuevas formulaciones de pellets de liberacion modificada para inhibidores de la bomba de protones
CA2491665A1 (fr) * 2004-12-24 2006-06-24 Louis Cartilier Formulation de comprime pour liberation soutenue de principe actif
RU2008113439A (ru) * 2005-09-09 2009-10-20 Лабофарм Инк. (CA) Композиции с замедленным высвобождением лекарственного средства
EA014739B1 (ru) * 2005-09-09 2011-02-28 Лабофарм Инк. Композиция тразодона для введения один раз в день
CA2621657C (en) * 2005-09-21 2014-06-17 Surmodics, Inc. In situ occluding compositions comprising natural biodegradable polysaccharides polymerized by a redox pair
US8241656B2 (en) * 2005-09-21 2012-08-14 Surmodics, Inc Articles including natural biodegradable polysaccharides and uses thereof
CN101304764B (zh) * 2005-11-11 2012-12-05 旭化成化学株式会社 控释固体制剂
WO2008073295A2 (en) * 2006-12-07 2008-06-19 Surmodics, Inc. Latent stabilization of bioactive agents releasable from implantable medical articles
CA2723192A1 (en) 2008-05-07 2009-11-12 Surmodics, Inc. Delivery of nucleic acid complexes from particles
EP2323633B1 (de) * 2008-09-04 2012-03-21 Bristol-Myers Squibb Company Stabile pharmazeutische zusammensetzung zur optimierten abgabe eines hiv-attachment-inhibitors
CN107028908A (zh) * 2008-10-27 2017-08-11 阿尔扎公司 对乙酰氨基酚/曲马多口服延释剂型
US20100260842A1 (en) * 2009-04-06 2010-10-14 Rashmi Nair Pseudoephedrine pharmaceutical formulations
US8901092B2 (en) 2010-12-29 2014-12-02 Surmodics, Inc. Functionalized polysaccharides for active agent delivery

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3065143A (en) * 1960-04-19 1962-11-20 Richardson Merrell Inc Sustained release tablet
US4167558A (en) * 1976-02-13 1979-09-11 Hoffmann-La Roche Inc. Novel sustained release tablet formulations
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4610870A (en) * 1984-10-05 1986-09-09 E. R. Squibb & Sons, Inc. Controlled release formulation
US4734285A (en) * 1985-10-28 1988-03-29 The Dow Chemical Company Sustained release compositions
US4704285A (en) * 1985-11-18 1987-11-03 The Dow Chemical Company Sustained release compositions comprising hydroxypropyl cellulose ethers
US4775535A (en) * 1986-04-04 1988-10-04 Hans Lowey Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
US4855143A (en) * 1986-04-04 1989-08-08 Hans Lowey Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
CA2041774C (en) * 1990-11-27 1994-04-19 Mircea A. Mateescu Use of cross-linked amylose as a matrix for the slow release of biologically active compounds
US5603956A (en) * 1990-11-27 1997-02-18 Labopharm Inc. Cross-linked enzymatically controlled drug release
NL9201196A (nl) * 1992-07-03 1994-02-01 Tno Preparaat voor de gereguleerde afgifte van een werkzame stof en werkwijze ter bereiding van een dergelijk preparaat.
HU221591B (hu) * 1992-07-24 2002-11-28 Labopharm Inc. Keresztkötéses polihidroxil-származék enzimatikusan szabályozott hatóanyag-kibocsátáshoz
US5616343A (en) * 1993-03-25 1997-04-01 Labopharm, Inc. Cross-linked amylose as a binder/disintegrant in tablets
IT1282650B1 (it) * 1996-02-19 1998-03-31 Jagotec Ag Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici

Also Published As

Publication number Publication date
DK0954290T3 (da) 2003-09-22
PT954290E (pt) 2003-10-31
PL187764B1 (pl) 2004-10-29
KR20000005337A (ko) 2000-01-25
JP2000507561A (ja) 2000-06-20
EP0954290B1 (de) 2003-05-21
KR100439614B1 (ko) 2004-10-14
AU711089B2 (en) 1999-10-07
JP4166278B2 (ja) 2008-10-15
AU2283297A (en) 1997-10-29
CZ325498A3 (cs) 1999-03-17
NO321862B1 (no) 2006-07-17
NO984703D0 (no) 1998-10-08
CZ294342B6 (cs) 2004-12-15
WO1997037639A1 (fr) 1997-10-16
DE69722247D1 (de) 2003-06-26
DE69722247T2 (de) 2004-04-01
ZA973054B (en) 1998-06-01
CA2173818A1 (fr) 1997-10-11
ES2200166T3 (es) 2004-03-01
BR9708772A (pt) 2000-01-04
MY115535A (en) 2003-07-31
CN1218396A (zh) 1999-06-02
PL329285A1 (en) 1999-03-15
IL126477A (en) 2001-10-31
IL126477A0 (en) 1999-08-17
TR199802034T2 (xx) 1999-02-22
NO984703L (no) 1998-12-08
US5885615A (en) 1999-03-23
NZ332576A (en) 2000-03-27
EP0954290A1 (de) 1999-11-10

Similar Documents

Publication Publication Date Title
DE69722247D1 (de) Pharmazeutische tablette mit verzögerter freisetzung, enthaltend eine matrix aus quervernetzter amylose und hydroxypropyl methylzellulose
DE69636724D1 (de) Drei verschiedene polymertypen enthaltende formulierung mit verzögerter freigabe
DK0841903T3 (da) Orale farmaceutiske præparater indeholdende antimikrobielt virksomme aktivstoffer og sustained release pantoprazol
ATE161174T1 (de) Feste zubereitung mit hoher freisetzung, ihre herstellung und verwendung
NO20001042D0 (no) Oftalmiske preparater med forsinket frigivelse inneholdende vannoppløselige medikamenter
ATE269709T1 (de) Tablette mit verzögerter freigabe enthaltend einen blutzuckersenkenden wirkstoff und einen antihyperglyzemischen wirkstoff
DE60038536D1 (de) Matrixsystem mit verzögerter freisetzung für hochlösliche wirkstoffe
DE69431800D1 (de) Arzneiverabreichungssystem
AU2793989A (en) Method for preparing a solid sustained release form of a functionally active composition and the dosage form so obtained
CO5011082A1 (es) Formulacion medicamentosa con liberacion controlada de sus- tancia activa
AU3080392A (en) Sol-controlled gelatine-based thermocolloidal matrix for peroral prolonged action administration forms
CA2140032A1 (en) Cross-linked amylose material for enzymatically controlled drug release
DE59706576D1 (de) Orale zubereitung, enthaltend in einer in wässrigem medium quellbaren matrix wenigstens einen pharmazeutischen wirkstoff
AU7817891A (en) Pharmaceuaticals with delayed release of active agent
NO942228L (no) Ipsapiron-legemiddeltilberedning
HUP9902681A2 (hu) Térhálósított amilózt és hidroxi-propil-metil-cellulózt tartalmazó hordozóval készült szabályozott felszabadulású tabletta gyógyszerkészítmény

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0954290

Country of ref document: EP