ATE241360T1 - Blutlipoproteinspiegel regulierendes präparat - Google Patents
Blutlipoproteinspiegel regulierendes präparatInfo
- Publication number
- ATE241360T1 ATE241360T1 AT98201255T AT98201255T ATE241360T1 AT E241360 T1 ATE241360 T1 AT E241360T1 AT 98201255 T AT98201255 T AT 98201255T AT 98201255 T AT98201255 T AT 98201255T AT E241360 T1 ATE241360 T1 AT E241360T1
- Authority
- AT
- Austria
- Prior art keywords
- level regulating
- derivative
- compound
- lipoprotein level
- blood lipoprotein
- Prior art date
Links
- 102000004895 Lipoproteins Human genes 0.000 title 1
- 108090001030 Lipoproteins Proteins 0.000 title 1
- 239000008280 blood Substances 0.000 title 1
- 210000004369 blood Anatomy 0.000 title 1
- 230000001105 regulatory effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000036470 plasma concentration Effects 0.000 abstract 2
- HRTCGZZYZFEBHO-UHFFFAOYSA-N 2,2-diphenyl-1,3-dioxolane Chemical class O1CCOC1(C=1C=CC=CC=1)C1=CC=CC=C1 HRTCGZZYZFEBHO-UHFFFAOYSA-N 0.000 abstract 1
- ONRSPOWNRLCCGF-UHFFFAOYSA-N 2,2-diphenyloxolane Chemical class C1CCOC1(C=1C=CC=CC=1)C1=CC=CC=C1 ONRSPOWNRLCCGF-UHFFFAOYSA-N 0.000 abstract 1
- HVAUUPRFYPCOCA-AREMUKBSSA-N 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCOC[C@@H](OC(C)=O)COP([O-])(=O)OCC[N+](C)(C)C HVAUUPRFYPCOCA-AREMUKBSSA-N 0.000 abstract 1
- 102000015779 HDL Lipoproteins Human genes 0.000 abstract 1
- 108010010234 HDL Lipoproteins Proteins 0.000 abstract 1
- 102000057248 Lipoprotein(a) Human genes 0.000 abstract 1
- 108010033266 Lipoprotein(a) Proteins 0.000 abstract 1
- 108010003541 Platelet Activating Factor Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 150000001538 azepines Chemical class 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
- WYURNTSHIVDZCO-UHFFFAOYSA-N tetrahydrofuran Substances C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 1
- -1 tetrahydrofuran phospholipid Chemical class 0.000 abstract 1
- 239000003848 thrombocyte activating factor antagonist Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97201139 | 1997-04-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE241360T1 true ATE241360T1 (de) | 2003-06-15 |
Family
ID=8228215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98201255T ATE241360T1 (de) | 1997-04-18 | 1998-04-20 | Blutlipoproteinspiegel regulierendes präparat |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US6444664B1 (de) |
| AT (1) | ATE241360T1 (de) |
| DE (1) | DE69814979T2 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2448567T3 (es) * | 2008-10-30 | 2014-03-14 | Circomed Llc | Derivados de la tienotriazoldiazepina activos en apo A |
| MX354217B (es) | 2010-05-14 | 2018-02-19 | Dana Farber Cancer Inst Inc | Composiciones y metodos para el tratamiento de leucemia. |
| EP2571875A4 (de) | 2010-05-14 | 2013-10-30 | Dana Farber Cancer Inst Inc | Zusammensetzungen für männliches verhütungsmittel und verfahren zur verwendung |
| PL2902030T3 (pl) | 2010-05-14 | 2017-07-31 | Dana-Farber Cancer Institute, Inc. | Związki tienotriazolodiazepinowe do leczenia nowotworu |
| US9975896B2 (en) | 2013-07-25 | 2018-05-22 | Dana-Farber Cancer Institute, Inc. | Inhibitors of transcription factors and uses thereof |
| RU2016122654A (ru) | 2013-11-08 | 2017-12-14 | Дана-Фарбер Кэнсер Инститьют, Инк. | Комбинированная терапия злокачественной опухоли с использованием ингибиторов бромодоменового и экстратерминального (вет) белка |
| EP3099677A4 (de) | 2014-01-31 | 2017-07-26 | Dana-Farber Cancer Institute, Inc. | Diaminopyrimidinbenzolsulfonderivate und verwendungen davon |
| US10793571B2 (en) | 2014-01-31 | 2020-10-06 | Dana-Farber Cancer Institute, Inc. | Uses of diazepane derivatives |
| JP2017506666A (ja) | 2014-02-28 | 2017-03-09 | テンシャ セラピューティクス，インコーポレイテッド | 高インスリン血症に関連した症状の処置 |
| CN106715437A (zh) | 2014-08-08 | 2017-05-24 | 达纳-法伯癌症研究所股份有限公司 | 二氮杂环庚烷衍生物及其用途 |
| CN106793775B (zh) | 2014-08-08 | 2020-06-02 | 达纳-法伯癌症研究所股份有限公司 | 二氢碟啶酮衍生物及其用途 |
| KR20170068597A (ko) | 2014-10-27 | 2017-06-19 | 텐샤 세러퓨틱스 인코포레이티드 | 브로모도메인 저해제 |
| WO2016201370A1 (en) | 2015-06-12 | 2016-12-15 | Dana-Farber Cancer Institute, Inc. | Combination therapy of transcription inhibitors and kinase inhibitors |
| RU2018112953A (ru) | 2015-09-11 | 2019-10-14 | Дана-Фарбер Кэнсер Инститьют, Инк. | Ацетамидтиенотриазолодиазепины и пути их применения |
| EP3347021A4 (de) | 2015-09-11 | 2019-07-24 | Dana-Farber Cancer Institute, Inc. | Cyanothienotriazoldiazepine und verwendungen davon |
| MX2018006499A (es) | 2015-11-25 | 2018-08-01 | Dana Farber Cancer Inst Inc | Inhibidores de bromodominio bivalentes y usos de los mismos. |
| AU2019284971A1 (en) | 2018-06-13 | 2020-12-03 | Worg Pharmaceuticals (Zhejiang) Co., Ltd. | Preparation of condensed triazepine derivatives and their use as BET inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4977146A (en) | 1989-06-08 | 1990-12-11 | Merck & Co., Inc. | 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists |
| ATE195653T1 (de) | 1990-06-06 | 2000-09-15 | Ruth Korth | Behandlung von erkrankungen mit paf-antagonisten und verfahren zur bestimmung deren wirksamkeit |
| US5302590A (en) | 1992-12-18 | 1994-04-12 | Hoffmann-La Roche Inc. | Compounds useful as dual antagonists of platelet activating factor and leukotriene D4 |
| DK0801651T3 (da) | 1995-01-06 | 2001-10-22 | Hoffmann La Roche | Hydroxymethyl-imidazodiazepiner og deres estere |
-
1998
- 1998-04-17 US US09/062,395 patent/US6444664B1/en not_active Expired - Fee Related
- 1998-04-20 DE DE69814979T patent/DE69814979T2/de not_active Expired - Fee Related
- 1998-04-20 AT AT98201255T patent/ATE241360T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69814979D1 (de) | 2003-07-03 |
| US6444664B1 (en) | 2002-09-03 |
| DE69814979T2 (de) | 2004-05-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0875247 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |