ATE241701T1 - Verfahren zur herstellung von morpholinonukleotiden und verwendung derselben zur analyse und markierung von nukleinsäuresequenzen - Google Patents

Verfahren zur herstellung von morpholinonukleotiden und verwendung derselben zur analyse und markierung von nukleinsäuresequenzen

Info

Publication number
ATE241701T1
ATE241701T1 AT00906441T AT00906441T ATE241701T1 AT E241701 T1 ATE241701 T1 AT E241701T1 AT 00906441 T AT00906441 T AT 00906441T AT 00906441 T AT00906441 T AT 00906441T AT E241701 T1 ATE241701 T1 AT E241701T1
Authority
AT
Austria
Prior art keywords
sub
line
formulae
sup
description
Prior art date
Application number
AT00906441T
Other languages
English (en)
Inventor
Florence Marciacq
Sylvie Sauvaigo
Jean-Francois Mouret
Jean-Paul Issartel
Didier Molko
Original Assignee
Commissariat Energie Atomique
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9902170A external-priority patent/FR2790004B1/fr
Application filed by Commissariat Energie Atomique, Centre Nat Rech Scient filed Critical Commissariat Energie Atomique
Application granted granted Critical
Publication of ATE241701T1 publication Critical patent/ATE241701T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT00906441T 1999-02-22 2000-02-21 Verfahren zur herstellung von morpholinonukleotiden und verwendung derselben zur analyse und markierung von nukleinsäuresequenzen ATE241701T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9902170A FR2790004B1 (fr) 1999-02-22 1999-02-22 Procede de fabrication de morpholino-nucleotides, et utilisation de ceux-ci pour l'analyse et le marquage de sequences d'acides nucleiques
FR9912001A FR2790005B1 (fr) 1999-02-22 1999-09-27 Procede de fabrication de morpholino-nucleotides, et utilisation de ceux-ci pour l'analyse et le marquage de sequences d'acides nucleiques
PCT/FR2000/000427 WO2000050626A1 (fr) 1999-02-22 2000-02-21 Procede de fabrication de morpholino-nucleotides, et leur utilisation pour l'analyse et le marquage de sequences d'acides nucleiques

Publications (1)

Publication Number Publication Date
ATE241701T1 true ATE241701T1 (de) 2003-06-15

Family

ID=26234825

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00906441T ATE241701T1 (de) 1999-02-22 2000-02-21 Verfahren zur herstellung von morpholinonukleotiden und verwendung derselben zur analyse und markierung von nukleinsäuresequenzen

Country Status (10)

Country Link
US (4) US6838560B1 (de)
EP (1) EP1155140B1 (de)
JP (1) JP2003502013A (de)
AT (1) ATE241701T1 (de)
CA (1) CA2371890A1 (de)
DE (1) DE60002989T2 (de)
ES (1) ES2199778T3 (de)
FR (1) FR2790005B1 (de)
PT (1) PT1155140E (de)
WO (1) WO2000050626A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790005B1 (fr) * 1999-02-22 2004-01-30 Commissariat Energie Atomique Procede de fabrication de morpholino-nucleotides, et utilisation de ceux-ci pour l'analyse et le marquage de sequences d'acides nucleiques
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
US7927779B2 (en) * 2005-06-30 2011-04-19 Taiwan Semiconductor Manufacturing Companym, Ltd. Water mark defect prevention for immersion lithography
US9778188B2 (en) 2009-03-11 2017-10-03 Industrial Technology Research Institute Apparatus and method for detection and discrimination molecular object
US9482615B2 (en) 2010-03-15 2016-11-01 Industrial Technology Research Institute Single-molecule detection system and methods
US9670243B2 (en) 2010-06-02 2017-06-06 Industrial Technology Research Institute Compositions and methods for sequencing nucleic acids
US8865078B2 (en) 2010-06-11 2014-10-21 Industrial Technology Research Institute Apparatus for single-molecule detection
WO2012177656A2 (en) 2011-06-19 2012-12-27 Abogen, Inc. Devices, solutions and methods for sample collection
JP2017510284A (ja) * 2014-04-10 2017-04-13 ディーエヌエー ジェノテック インク 過ヨウ素酸塩を用いる微生物溶解のための方法およびシステム

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515781A (en) * 1983-02-23 1985-05-07 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services 2',5'-Riboadenylate-morpholinoadenylate nucleotides
US5849482A (en) * 1988-09-28 1998-12-15 Epoch Pharmaceuticals, Inc. Crosslinking oligonucleotides
FR2710068B1 (fr) 1993-09-13 1995-10-20 Commissariat Energie Atomique Dérivés de nucléosides, procédés de fabrication de ces dérivés de nucléosides et anticorps polyclonaux et monoclonaux spécifiques de ces dérivés.
SE9500342D0 (sv) 1995-01-31 1995-01-31 Marek Kwiatkowski Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation
AU771579B2 (en) * 1998-10-26 2004-03-25 Avi Biopharma, Inc. p53 antisense agent and method
FR2790005B1 (fr) * 1999-02-22 2004-01-30 Commissariat Energie Atomique Procede de fabrication de morpholino-nucleotides, et utilisation de ceux-ci pour l'analyse et le marquage de sequences d'acides nucleiques

Also Published As

Publication number Publication date
DE60002989T2 (de) 2004-05-19
DE60002989D1 (de) 2003-07-03
CA2371890A1 (fr) 2000-08-31
US7105661B2 (en) 2006-09-12
PT1155140E (pt) 2003-10-31
EP1155140A1 (de) 2001-11-21
US20040209332A1 (en) 2004-10-21
FR2790005A1 (fr) 2000-08-25
FR2790005B1 (fr) 2004-01-30
EP1155140B1 (de) 2003-05-28
WO2000050626A1 (fr) 2000-08-31
US20050070708A1 (en) 2005-03-31
ES2199778T3 (es) 2004-03-01
US6838560B1 (en) 2005-01-04
US7081526B2 (en) 2006-07-25
US20060183204A1 (en) 2006-08-17
JP2003502013A (ja) 2003-01-21
US7314928B2 (en) 2008-01-01

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