ATE241959T1 - Formulierungen von steroidlösungen zur inhalativen verabreichung - Google Patents

Formulierungen von steroidlösungen zur inhalativen verabreichung

Info

Publication number
ATE241959T1
ATE241959T1 AT00956216T AT00956216T ATE241959T1 AT E241959 T1 ATE241959 T1 AT E241959T1 AT 00956216 T AT00956216 T AT 00956216T AT 00956216 T AT00956216 T AT 00956216T AT E241959 T1 ATE241959 T1 AT E241959T1
Authority
AT
Austria
Prior art keywords
formulations
inhalation administration
steroid solutions
relates
solutions
Prior art date
Application number
AT00956216T
Other languages
English (en)
Inventor
Chiara Malvolti
Raffaella Garzia
Gaetano Brambilla
Paolo Chiesi
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Application granted granted Critical
Publication of ATE241959T1 publication Critical patent/ATE241959T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
AT00956216T 1999-07-23 2000-07-20 Formulierungen von steroidlösungen zur inhalativen verabreichung ATE241959T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI001625A IT1313553B1 (it) 1999-07-23 1999-07-23 Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
PCT/EP2000/006916 WO2001007014A1 (en) 1999-07-23 2000-07-20 Formulations of steroid solutions for inhalatory administration

Publications (1)

Publication Number Publication Date
ATE241959T1 true ATE241959T1 (de) 2003-06-15

Family

ID=11383393

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00956216T ATE241959T1 (de) 1999-07-23 2000-07-20 Formulierungen von steroidlösungen zur inhalativen verabreichung

Country Status (14)

Country Link
US (1) US6967017B1 (de)
EP (1) EP1198224B1 (de)
AT (1) ATE241959T1 (de)
AU (1) AU6825000A (de)
CZ (1) CZ299071B6 (de)
DE (1) DE60003183T2 (de)
DK (1) DK1198224T3 (de)
ES (1) ES2200913T3 (de)
HU (1) HUP0201956A3 (de)
IT (1) IT1313553B1 (de)
NO (1) NO20020342D0 (de)
PL (1) PL198817B1 (de)
PT (1) PT1198224E (de)
WO (1) WO2001007014A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20010614A1 (it) * 2001-10-16 2003-04-16 Italchimici S P A Preparazione farmaceutica di una soluzione idro/propilenica di budesonide e suo procedimento di preparazione.
US20040265238A1 (en) * 2003-06-27 2004-12-30 Imtiaz Chaudry Inhalable formulations for treating pulmonary hypertension and methods of using same
ITMI20032054A1 (it) 2003-10-22 2005-04-23 Monteres S R L Processo per la preparazione di sospensioni farmaceutiche da inalare.
AR041873A1 (es) * 2003-10-30 2005-06-01 Pablo Cassara Srl Lab Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante
PE20050941A1 (es) 2003-12-16 2005-11-08 Nycomed Gmbh Suspensiones acuosas de ciclesonida para nebulizacion
ITRM20040268A1 (it) * 2004-05-31 2004-08-31 Italchimici S P A Formulazione farmaceutica di una soluzione stabile di formoterolo per via inalatoria e suo precedimento di preparazione.
EP1850831B1 (de) 2005-02-25 2015-12-02 CHIESI FARMACEUTICI S.p.A. Pharmazeutische aerosol-formulierungen für unter druck stehende dosieraerosole mit einem sequestriermittel
GB0604141D0 (en) * 2006-03-01 2006-04-12 Arrow Int Ltd Nebulizer formulation
CZ302596B6 (cs) * 2007-04-12 2011-07-27 Jihoceská univerzita v Ceských Budejovicích, Zemedelská fakulta Zpusob zpracování biomasy jetele lucního

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3361306A (en) 1966-03-31 1968-01-02 Merck & Co Inc Aerosol unit dispensing uniform amounts of a medically active ingredient
US3622053A (en) 1969-12-10 1971-11-23 Schering Corp Aerosol inhaler with flip-up nozzle
MX3864E (es) 1975-05-27 1981-08-26 Syntex Corp Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona
US4185100A (en) 1976-05-13 1980-01-22 Johnson & Johnson Topical anti-inflammatory drug therapy
US4499108A (en) 1983-06-08 1985-02-12 Schering Corporation Stable pleasant-tasting albuterol sulfate pharmaceutical formulations
IT1196142B (it) 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
US5192528A (en) 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
GB8828477D0 (en) 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
US5225183A (en) 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
IL97065A (en) 1990-02-02 1994-01-25 Fisons Plc Repellent preparations for aerosol
AU8642391A (en) 1990-12-19 1992-07-22 Smithkline Beecham Corporation Aerosol formulations
US6006745A (en) 1990-12-21 1999-12-28 Minnesota Mining And Manufacturing Company Device for delivering an aerosol
EP0504112A3 (en) 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
DK0585379T3 (da) 1991-05-21 1999-06-21 Abbott Lab Aerosol-inhalationsindretning
CZ282972B6 (cs) 1991-08-29 1997-11-12 Broncho-Air Medizintechnik Ag Lékařský přístroj pro inhalování dávkovaných aerosolů
NZ244439A (en) 1991-09-25 1994-01-26 Fisons Plc Pressurised aerosol compositions comprising hydrofluoroalkane, dispersed
IL104068A (en) 1991-12-12 1998-10-30 Glaxo Group Ltd Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
JP3908269B2 (ja) 1991-12-18 2007-04-25 スリーエム カンパニー 懸濁エアゾール製剤
DE4230876A1 (de) 1992-03-17 1993-09-23 Asta Medica Ag Druckgaspackungen unter verwendung von polyoxyethylen-glyceryl-oleaten
ATE177941T1 (de) 1992-12-09 1999-04-15 Boehringer Ingelheim Pharma Stabilisierte medizinische aerosollösungen
SE9203743D0 (sv) 1992-12-11 1992-12-11 Astra Ab Efficient use
AU4066693A (en) 1992-12-23 1994-07-19 Bernhard Hugemann Compacted drug body for use in the mechanical generation of inhalable active-substance particles
ES2107203T3 (es) 1993-03-17 1997-11-16 Minnesota Mining & Mfg Una formulacion de aerosol que contiene un adyuvante de dispersion derivado de un diol-diacido.
ES2122261T3 (es) 1993-03-17 1998-12-16 Minnesota Mining & Mfg Formulacion de aerosol que contiene un adyuvante de dispersion derivado de un ester, una amida o un mercaptoester.
US6596260B1 (en) 1993-08-27 2003-07-22 Novartis Corporation Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
PT735884E (pt) 1993-12-20 2000-09-29 Minnesota Mining & Mfg Formulacoes de aerossol de flunisolida
GB9425160D0 (en) 1994-12-10 1995-02-08 Glaxo Group Ltd Medicaments
EE9700138A (et) 1994-12-22 1997-12-15 Astra Aktiebolag Aerosoolravimvormid
GB9426252D0 (en) 1994-12-24 1995-02-22 Glaxo Group Ltd Pharmaceutical composition
DE4446891A1 (de) * 1994-12-27 1996-07-04 Falk Pharma Gmbh Stabile wäßrige Budesonid-Lösung
US5653961A (en) 1995-03-31 1997-08-05 Minnesota Mining And Manufacturing Company Butixocort aerosol formulations in hydrofluorocarbon propellant
TR199701170T1 (xx) 1995-04-14 1998-02-21 Glaxo Wellcome Inc. Beklometazon dipropionat i�in �l��lm�� doz inhaleri.
HU219899B (hu) 1995-04-14 2001-09-28 Glaxo Wellcome Inc. Inhalálóberendezés flutikaszon-propionát adagolására mért dózisban
TR199701169T1 (xx) 1995-04-14 1998-03-21 Glaxo Wellcome Inc. Salmeterol i�in �l��lm�� doz inhaleri.
HU219900B (hu) 1995-04-14 2001-09-28 Glaxo Wellcome Inc. Mért dózist adagoló inhalálóberendezés
GB9612297D0 (en) 1996-06-11 1996-08-14 Minnesota Mining & Mfg Medicinal aerosol formulations
JP2000514085A (ja) 1996-07-08 2000-10-24 ローヌ―プーラン・ロウラー・リミテッド 医薬シクロスポリンaエーロゾル溶液処方物
AU3811897A (en) 1996-07-24 1998-02-10 Oglios Therapeutics, Inc. Antisense oligonucleotides as antibacterial agents
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
GB9620187D0 (en) 1996-09-27 1996-11-13 Minnesota Mining & Mfg Medicinal aerosol formulations
DE69734017T2 (de) 1996-12-04 2006-06-14 Link Products Ltd Arzneimittelzusammensetzungen und vorrichtungen zu deren verabreichung
US6413496B1 (en) 1996-12-04 2002-07-02 Biogland Ireland (R&D) Limited Pharmaceutical compositions and devices for their administration
JP2001511160A (ja) 1997-02-05 2001-08-07 ヤゴ リサーチ アクチェンゲゼルシャフト 医学用エアゾール配合物
US6126919A (en) 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
US5891419A (en) 1997-04-21 1999-04-06 Aeropharm Technology Limited Environmentally safe flunisolide aerosol formulations for oral inhalation
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
GB2326334A (en) 1997-06-13 1998-12-23 Chiesi Farma Spa Pharmaceutical aerosol compositions
BR7702049U (pt) 1997-09-05 1999-09-14 Chiesi Farma Spa Bico pulverizador para utilização em inalador oral para medicamentos aerossóis
US5954047A (en) 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
US6045784A (en) 1998-05-07 2000-04-04 The Procter & Gamble Company Aerosol package compositions containing fluorinated hydrocarbon propellants
SE9802073D0 (sv) 1998-06-11 1998-06-11 Astra Ab New use
BR9911351A (pt) 1998-06-18 2001-03-13 Boehringer Ingelheim Pharma Formulações farmacêuticas para aerossóis com duas ou mais substâncias ativas
US6451285B2 (en) 1998-06-19 2002-09-17 Baker Norton Pharmaceuticals, Inc. Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant
US6241969B1 (en) * 1998-06-26 2001-06-05 Elan Corporation Plc Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
ES2234266T3 (es) 1998-07-24 2005-06-16 Jago Research Ag Formulaciones medicas para aerosoles.
JP4672143B2 (ja) 1998-08-04 2011-04-20 ヤゴテック アーゲー 医薬用エーロゾル製剤
DE19847969A1 (de) 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Lagerfähig flüssige Formulierung mit Formoterol
DE59901669D1 (de) 1998-10-17 2002-07-11 Boehringer Ingelheim Pharma Lagerfähiges wirkstoffkonzentrat mit formoterol
PL200941B1 (pl) 1998-11-13 2009-02-27 Jagotec Ag Suchy proszkowy preparat inhalacyjny
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
IT1303788B1 (it) 1998-11-25 2001-02-23 Chiesi Farma Spa Formulazioni di aerosol medicinali.
US6004537A (en) * 1998-12-18 1999-12-21 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol
US6290930B1 (en) 1998-12-18 2001-09-18 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes and budesonide
ATE363892T1 (de) 1999-03-05 2007-06-15 Chiesi Farma Spa Verbesserte pulverformulierungen zur inhalation
US6315985B1 (en) 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
AU2206801A (en) 1999-12-24 2001-07-09 Alan Leslie Cripps Pharmaceutical aerosol formulation of salmeterol and fluticasone propionate
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
IT1318514B1 (it) 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
AU2000250701B2 (en) 2000-05-22 2004-07-01 Chiesi Farmaceutici S.P.A. Stable pharmaceutical solution formulations for pressurised metered dose inhalers

Also Published As

Publication number Publication date
PL198817B1 (pl) 2008-07-31
DE60003183T2 (de) 2004-04-29
HUP0201956A2 (en) 2002-10-28
AU6825000A (en) 2001-02-13
US6967017B1 (en) 2005-11-22
ES2200913T3 (es) 2004-03-16
IT1313553B1 (it) 2002-09-09
NO20020342L (no) 2002-01-22
DE60003183D1 (de) 2003-07-10
PL353470A1 (en) 2003-11-17
NO20020342D0 (no) 2002-01-22
DK1198224T3 (da) 2003-09-29
CZ2002257A3 (cs) 2002-05-15
WO2001007014A1 (en) 2001-02-01
EP1198224B1 (de) 2003-06-04
ITMI991625A0 (it) 1999-07-23
ITMI991625A1 (it) 2001-01-23
CZ299071B6 (cs) 2008-04-16
EP1198224A1 (de) 2002-04-24
HUP0201956A3 (en) 2003-10-28
PT1198224E (pt) 2003-10-31

Similar Documents

Publication Publication Date Title
WO2005037246A3 (de) Wässrige aerosol-zubereitung
JP4603687B2 (ja) 点鼻用液剤
BG106906A (bg) Пуринови производни
ATE299740T1 (de) Kombination aus einem no-donor und einem antioxidans zur behanndlung sexueller störungen
WO2003079993A3 (en) hGH (HUMAN GROWTH HORMONE) FORMULATIONS FOR PULMONARY ADMINISTRATION
WO2005044226A3 (en) Lipid formulations for spontaneous drug encapsulation
ATE241959T1 (de) Formulierungen von steroidlösungen zur inhalativen verabreichung
NO20023875D0 (no) Stabilt nasalt, oralt eller sublingualt anvendbart preparat
DK1280558T3 (da) Halvfast indgivelsesvehikel og farmaceutiske sammensætninger
WO2001047913A3 (de) Substituierte n-benzyl-indol-3-yl- glyoxylsäure-derivate antitumorwirkung
ATE240717T1 (de) Wässrige formulierung zur nasalen verabreichung
DK1673074T3 (da) Flydende præparat, indeholdende tobramycin
DK1343472T3 (da) Thixotropisk næsespray
PT92188B (pt) Processo para a preparacao de uma solucao aquosa contendo acido cromoglicico e salbutamol
WO2004033484A3 (en) Use of stable glutamine derivatives to improve drug absorption
AU2001258859A1 (en) Pralmorelin-containing nasal drop preparations
NO20033451D0 (no) Medikamenter
CN116437903A (zh) 肝素组合物在通过吸入途径通过软雾吸入器或振动网状技术雾化器治疗病毒性肺病、急性和/或慢性肺病中的用途
JPH10130148A (ja) ネブライザー用組成物
ATE284696T1 (de) Pharmazeutische zusammensetzung enthaltend salmeterol und budesonid zur behandlung von atemkrankheiten
SE0103749D0 (sv) Treatment of congestive heart failure
ATE269063T1 (de) Formulierungen zur transdermalen verabreichung von fenoldopam
BR0205625A (pt) Formulações nasais
WO2004108061A3 (en) Stable injectable pharmaceutical composition of thiopental; method for stabilizing aqueous solutions of thiopental and, use of thiopental for producing a medicament

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1198224

Country of ref document: EP