ATE242206T1 - Substituierte derivate von benzosulphonamiden als hemmer des enzym cyclooxygenase ii - Google Patents

Substituierte derivate von benzosulphonamiden als hemmer des enzym cyclooxygenase ii

Info

Publication number
ATE242206T1
ATE242206T1 AT98902137T AT98902137T ATE242206T1 AT E242206 T1 ATE242206 T1 AT E242206T1 AT 98902137 T AT98902137 T AT 98902137T AT 98902137 T AT98902137 T AT 98902137T AT E242206 T1 ATE242206 T1 AT E242206T1
Authority
AT
Austria
Prior art keywords
benzosulphonamids
inhibitors
substituted derivatives
enzyme cyclooxygenase
cyclooxygenase
Prior art date
Application number
AT98902137T
Other languages
English (en)
Inventor
Michael Hartmann
Peter Kremminger
Heinz Blaschke
Dagmar Stimmeder
Harald Fellier
Franz Rovenszky
Original Assignee
Nycomed Austria Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Austria Gmbh filed Critical Nycomed Austria Gmbh
Application granted granted Critical
Publication of ATE242206T1 publication Critical patent/ATE242206T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
    • C07C323/67—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfonamide groups, bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT98902137T 1997-02-03 1998-02-03 Substituierte derivate von benzosulphonamiden als hemmer des enzym cyclooxygenase ii ATE242206T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0016597A ATA16597A (de) 1997-02-03 1997-02-03 Neue substituierte p-sulfonylaminobenzol- sulfonsäureamide
PCT/GB1998/000342 WO1998033769A1 (en) 1997-02-03 1998-02-03 Substituted derivatives of benzosulphonamides as inhibitors of the enzyme cyclooxygenase ii

Publications (1)

Publication Number Publication Date
ATE242206T1 true ATE242206T1 (de) 2003-06-15

Family

ID=3483303

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0016597A ATA16597A (de) 1997-02-03 1997-02-03 Neue substituierte p-sulfonylaminobenzol- sulfonsäureamide
AT98902137T ATE242206T1 (de) 1997-02-03 1998-02-03 Substituierte derivate von benzosulphonamiden als hemmer des enzym cyclooxygenase ii

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0016597A ATA16597A (de) 1997-02-03 1997-02-03 Neue substituierte p-sulfonylaminobenzol- sulfonsäureamide

Country Status (7)

Country Link
US (1) US6297282B1 (de)
EP (1) EP0968180B1 (de)
JP (1) JP2001509800A (de)
AT (2) ATA16597A (de)
AU (1) AU5875498A (de)
DE (1) DE69815311D1 (de)
WO (1) WO1998033769A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040072889A1 (en) * 1997-04-21 2004-04-15 Pharmacia Corporation Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
US6649645B1 (en) * 1998-12-23 2003-11-18 Pharmacia Corporation Combination therapy of radiation and a COX-2 inhibitor for treatment of neoplasia
US7507767B2 (en) 2001-02-08 2009-03-24 Schering Corporation Cannabinoid receptor ligands
US7067539B2 (en) 2001-02-08 2006-06-27 Schering Corporation Cannabinoid receptor ligands
US20060167074A1 (en) * 2001-06-19 2006-07-27 Norbert Muller Methods and compositions for the treatment of psychiatric disorders
DE10129320A1 (de) * 2001-06-19 2003-04-10 Norbert Mueller Verwendung von COX-2 Inhibitoren zur Behandlung von Schizophrenie, wahnhaften Störungen, affektiven Störungen oder Ticstörungen
CN100567266C (zh) 2001-11-14 2009-12-09 先灵公司 类大麻苷受体配体
US20030220374A1 (en) * 2002-01-14 2003-11-27 Pharmacia Corporation Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors
US20030212138A1 (en) * 2002-01-14 2003-11-13 Pharmacia Corporation Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor
DE60319714T2 (de) 2002-06-19 2009-04-02 Schering Corp. Agonisten des cannabinoidrezeptors
US20040147581A1 (en) * 2002-11-18 2004-07-29 Pharmacia Corporation Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
AU2003303041B2 (en) 2002-12-13 2008-07-24 Warner-Lambert Company Llc Alpha-2-delta ligand to treat lower urinary tract symptoms
TW200505902A (en) 2003-03-20 2005-02-16 Schering Corp Cannabinoid receptor ligands
US20040220155A1 (en) * 2003-03-28 2004-11-04 Pharmacia Corporation Method of providing a steroid-sparing benefit with a cyclooxygenase-2 inhibitor and compositions therewith
ES2275218T3 (es) 2003-05-07 2007-06-01 Osteologix A/S Sales de estroncio hidrosolubles para el tratamiento de afecciones de cartilagos y/o huesos.
US20050014729A1 (en) * 2003-07-16 2005-01-20 Pharmacia Corporation Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith
US20050119262A1 (en) * 2003-08-21 2005-06-02 Pharmacia Corporation Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent
US20050113409A1 (en) * 2003-09-03 2005-05-26 Pharmacia Corporation Method for the prevention or treatment of pain, inflammation and inflammation-related disorders with a Cox-2 selective inhibitor in combination with a nitric oxide-donating agent and compositions therewith
BRPI0506994A (pt) 2004-01-22 2007-07-03 Pfizer derivados de triazol que inibem a atividade antagonista da vasopressina
CA2563963A1 (en) * 2004-04-28 2005-11-10 Pfizer Inc. 3-heterocyclyl-4-phenyl-triazole derivatives as inhibitors of the vasopressin v1a receptor
WO2006121887A2 (en) * 2005-05-05 2006-11-16 Cook Biotech Incorporated Implantable materials and methods for inhibiting tissue adhesion formation
CA2673545A1 (en) 2006-12-22 2008-07-03 Recordati Ireland Limited Combination therapy of lower urinary tract disorders with .alpha.2.delta. ligands and nsaids
US8815828B2 (en) * 2008-07-02 2014-08-26 University Of Florida Research Foundation, Inc. Therapeutic combinations for use in neoplasia
US11583516B2 (en) 2016-09-07 2023-02-21 Trustees Of Tufts College Dash inhibitors, and uses related thereto

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5604260A (en) * 1992-12-11 1997-02-18 Merck Frosst Canada Inc. 5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2
DK0848703T3 (da) * 1995-07-21 2001-01-02 Nycomed Austria Gmbh Derivater af benzosulfonamider som inhibitorer for enzymet cyclooxygenase II
DE19533644A1 (de) * 1995-09-12 1997-03-13 Nycomed Arzneimittel Gmbh Neue Benzolsulfonamide
US6146615A (en) * 1999-01-11 2000-11-14 The University Of Toledo Contrast agents for image enhancement in magnetic resonance imaging

Also Published As

Publication number Publication date
ATA16597A (de) 1998-04-15
US6297282B1 (en) 2001-10-02
JP2001509800A (ja) 2001-07-24
WO1998033769A1 (en) 1998-08-06
EP0968180A1 (de) 2000-01-05
EP0968180B1 (de) 2003-06-04
AU5875498A (en) 1998-08-25
DE69815311D1 (de) 2003-07-10

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties