ATE242760T1 - Tilidin-mesylat, verfahren zu dessen herstellung und pharmazeutische zusammensetzungen - Google Patents
Tilidin-mesylat, verfahren zu dessen herstellung und pharmazeutische zusammensetzungenInfo
- Publication number
- ATE242760T1 ATE242760T1 AT99916009T AT99916009T ATE242760T1 AT E242760 T1 ATE242760 T1 AT E242760T1 AT 99916009 T AT99916009 T AT 99916009T AT 99916009 T AT99916009 T AT 99916009T AT E242760 T1 ATE242760 T1 AT E242760T1
- Authority
- AT
- Austria
- Prior art keywords
- tilidine
- production
- pharmaceutical compositions
- tilidine mesylate
- mesylate
- Prior art date
Links
- WDEFBBTXULIOBB-WBVHZDCISA-N dextilidine Chemical compound C=1C=CC=CC=1[C@@]1(C(=O)OCC)CCC=C[C@H]1N(C)C WDEFBBTXULIOBB-WBVHZDCISA-N 0.000 title abstract 4
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 title abstract 3
- 229960001402 tilidine Drugs 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- NTIZESTWPVYFNL-UHFFFAOYSA-N Methyl isobutyl ketone Chemical compound CC(C)CC(C)=O NTIZESTWPVYFNL-UHFFFAOYSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE980322 | 1998-04-28 | ||
| PCT/IE1999/000024 WO1999055662A1 (en) | 1998-04-28 | 1999-04-09 | Tilidine mesylate, processes for its preparation and pharmaceutical composition thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE242760T1 true ATE242760T1 (de) | 2003-06-15 |
Family
ID=11041785
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99916009T ATE242760T1 (de) | 1998-04-28 | 1999-04-09 | Tilidin-mesylat, verfahren zu dessen herstellung und pharmazeutische zusammensetzungen |
| AT0901099A AT500119A1 (de) | 1998-04-28 | 1999-04-09 | Tilidinmethansulfonat, verfahren zu seiner herstellung und pharmazeutische masse hiervon |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0901099A AT500119A1 (de) | 1998-04-28 | 1999-04-09 | Tilidinmethansulfonat, verfahren zu seiner herstellung und pharmazeutische masse hiervon |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1073625B1 (de) |
| AT (2) | ATE242760T1 (de) |
| AU (1) | AU744888B2 (de) |
| DE (2) | DE69908771T2 (de) |
| DK (1) | DK1073625T3 (de) |
| ES (1) | ES2204119T3 (de) |
| PT (1) | PT1073625E (de) |
| WO (1) | WO1999055662A1 (de) |
| ZA (1) | ZA200001587B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19859636A1 (de) * | 1998-12-23 | 2000-06-29 | Hexal Ag | Kontrolliert freisetzende pharmazeutische Zusammensetzung mit Tilidinmesylat als Wirkstoff |
| EP2168945A1 (de) | 2008-09-26 | 2010-03-31 | Hexal Ag | Kristalline Formen von Tilidinmesylat |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR5978M (de) * | 1965-11-19 | 1968-04-22 | ||
| DE1923620C3 (de) * | 1968-05-08 | 1971-06-24 | Goedecke Ag | Verfahren zur Herstellung basisch substituierter Cyclohexene bzw. von deren Salzen |
| DE1768704B1 (de) * | 1968-06-21 | 1971-11-11 | Goedecke Ag | Verfahren zur Abtrennung von 3-trans-Dimethylamino-4-phenyl-4-trans-carbaethoxy-delta?-cyclohexen |
| DE2107871B2 (de) * | 1971-02-18 | 1973-07-19 | 1-phenyl-4-amino-cyclohex-2-en-1 carbonsaeureester, verfahren zu deren herstellung und diese enthaltende analgetisch wirksame arzneimittel | |
| CS214312B1 (cs) * | 1980-11-03 | 1982-04-09 | Ladislav David | Sposob přípravy 3-tran s-dimetylamina-A-tran karbetoxy-l-cyklohexénu |
| RO112851B1 (ro) * | 1992-10-26 | 1998-01-30 | Goedecke Ag | Derivat de tilidina, procedeu de preparare a acestuia si compozitie farmaceutica continand acest derivat |
-
1999
- 1999-04-09 PT PT99916009T patent/PT1073625E/pt unknown
- 1999-04-09 DE DE69908771T patent/DE69908771T2/de not_active Expired - Lifetime
- 1999-04-09 EP EP99916009A patent/EP1073625B1/de not_active Expired - Lifetime
- 1999-04-09 DE DE19981795T patent/DE19981795T1/de not_active Withdrawn
- 1999-04-09 DK DK99916009T patent/DK1073625T3/da active
- 1999-04-09 AU AU34402/99A patent/AU744888B2/en not_active Ceased
- 1999-04-09 WO PCT/IE1999/000024 patent/WO1999055662A1/en not_active Ceased
- 1999-04-09 ES ES99916009T patent/ES2204119T3/es not_active Expired - Lifetime
- 1999-04-09 AT AT99916009T patent/ATE242760T1/de active
- 1999-04-09 AT AT0901099A patent/AT500119A1/de not_active Application Discontinuation
-
2000
- 2000-03-29 ZA ZA200001587A patent/ZA200001587B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE990299A1 (en) | 2000-12-13 |
| AU744888B2 (en) | 2002-03-07 |
| DE19981795T1 (de) | 2001-05-10 |
| WO1999055662A1 (en) | 1999-11-04 |
| PT1073625E (pt) | 2003-11-28 |
| AU3440299A (en) | 1999-11-16 |
| ZA200001587B (en) | 2000-10-25 |
| DK1073625T3 (da) | 2003-09-29 |
| ES2204119T3 (es) | 2004-04-16 |
| DE69908771D1 (de) | 2003-07-17 |
| DE69908771T2 (de) | 2004-04-22 |
| EP1073625A1 (de) | 2001-02-07 |
| AT500119A1 (de) | 2005-10-15 |
| EP1073625B1 (de) | 2003-06-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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