ATE242877T1 - Zusammensetzungen und verfahren für die schnelle analyse von retikulozyten - Google Patents

Zusammensetzungen und verfahren für die schnelle analyse von retikulozyten

Info

Publication number: ATE242877T1
Authority: AT; Austria
Prior art keywords: reagent; group; reticulocytes; tris; bis
Prior art date: 1995-04-21

Application number

AT96912970T

Other languages

English (en)

Inventor

Young Ran Kim

Johanna Kantor

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-04-21

Filing date

1996-04-19

Publication date

2003-06-15

1996-04-19 Application filed by Abbott Lab filed Critical Abbott Lab

2003-06-15 Application granted granted Critical

2003-06-15 Publication of ATE242877T1 publication Critical patent/ATE242877T1/de

Links

238000000034 method Methods 0.000 title abstract 4
210000001995 reticulocyte Anatomy 0.000 title abstract 4
239000000203 mixture Substances 0.000 title 1
239000003153 chemical reaction reagent Substances 0.000 abstract 5
RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 3
TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 abstract 2
WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 abstract 2
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
KWGKDLIKAYFUFQ-UHFFFAOYSA-M lithium chloride Chemical compound [Li+].[Cl-] KWGKDLIKAYFUFQ-UHFFFAOYSA-M 0.000 abstract 2
ZWEVPYNPHSPIFU-AUGHYPCGSA-N (2r,3s,4r,5r)-2,3,4,5,6-pentahydroxy-n-[3-[3-[[(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanoyl]amino]propyl-[(4r)-4-[(3r,5s,7r,8r,9s,10s,12s,13r,14s,17r)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenan Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)N(CCCNC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)CCCNC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C)[C@@]2(C)[C@@H](O)C1 ZWEVPYNPHSPIFU-AUGHYPCGSA-N 0.000 abstract 1
UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 abstract 1
229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
239000007983 Tris buffer Substances 0.000 abstract 1
150000001447 alkali salts Chemical class 0.000 abstract 1
OWMVSZAMULFTJU-UHFFFAOYSA-N bis-tris Chemical compound OCCN(CCO)C(CO)(CO)CO OWMVSZAMULFTJU-UHFFFAOYSA-N 0.000 abstract 1
229920001400 block copolymer Polymers 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
239000000872 buffer Substances 0.000 abstract 1
239000001110 calcium chloride Substances 0.000 abstract 1
235000011148 calcium chloride Nutrition 0.000 abstract 1
229910001628 calcium chloride Inorganic materials 0.000 abstract 1
238000011534 incubation Methods 0.000 abstract 1
235000011147 magnesium chloride Nutrition 0.000 abstract 1
229910001629 magnesium chloride Inorganic materials 0.000 abstract 1
239000002736 nonionic surfactant Substances 0.000 abstract 1
239000011780 sodium chloride Substances 0.000 abstract 1
230000000087 stabilizing effect Effects 0.000 abstract 1
238000010186 staining Methods 0.000 abstract 1
ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical compound [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 abstract 1
LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 abstract 1
239000011592 zinc chloride Substances 0.000 abstract 1
235000005074 zinc chloride Nutrition 0.000 abstract 1
JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1402—Data analysis by thresholding or gating operations performed on the acquired signals or stored data
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1477—Multiparameters
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Pathology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Biochemistry (AREA)
Analytical Chemistry (AREA)
Physics & Mathematics (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Cell Biology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Dispersion Chemistry (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Investigating Or Analysing Biological Materials (AREA)
Sampling And Sample Adjustment (AREA)

AT96912970T 1995-04-21 1996-04-19 Zusammensetzungen und verfahren für die schnelle analyse von retikulozyten ATE242877T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/426,408 US5691204A (en)	1995-04-21	1995-04-21	Compositions and methods for the rapid analysis of reticulocytes
PCT/US1996/005520 WO1996033396A1 (en)	1995-04-21	1996-04-19	Compositions and methods for the rapid analysis of reticulocytes

Publications (1)

Publication Number	Publication Date
ATE242877T1 true ATE242877T1 (de)	2003-06-15

Family

ID=23690691

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96912970T ATE242877T1 (de)	1995-04-21	1996-04-19	Zusammensetzungen und verfahren für die schnelle analyse von retikulozyten

Country Status (7)

Country	Link
US (2)	US5691204A (de)
EP (1)	EP0842410B1 (de)
JP (1)	JP3600247B2 (de)
AT (1)	ATE242877T1 (de)
DE (1)	DE69628651T2 (de)
ES (1)	ES2201182T3 (de)
WO (1)	WO1996033396A1 (de)

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CN101988082B (zh)	2009-07-31	2015-04-08	深圳迈瑞生物医疗电子股份有限公司	白细胞分类计数试剂、试剂盒及其制备方法和白细胞分类计数的方法
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EP2798087B1 (de) *	2011-12-27	2018-03-07	Abbott Laboratories	Analyse von körperflüssigkeiten auf zellularer ebene
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CN109642248B (zh)	2016-03-17	2022-09-02	珀金埃尔默健康科学有限责任公司	液体样品中细胞的检测
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1995
- 1995-04-21 US US08/426,408 patent/US5691204A/en not_active Expired - Lifetime
1996
- 1996-04-19 ES ES96912970T patent/ES2201182T3/es not_active Expired - Lifetime
- 1996-04-19 EP EP96912970A patent/EP0842410B1/de not_active Expired - Lifetime
- 1996-04-19 DE DE69628651T patent/DE69628651T2/de not_active Expired - Lifetime
- 1996-04-19 WO PCT/US1996/005520 patent/WO1996033396A1/en not_active Ceased
- 1996-04-19 AT AT96912970T patent/ATE242877T1/de not_active IP Right Cessation
- 1996-04-19 JP JP53197596A patent/JP3600247B2/ja not_active Expired - Lifetime
- 1996-12-20 US US08/777,727 patent/US5773299A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US5691204A (en)	1997-11-25
EP0842410B1 (de)	2003-06-11
JPH11508353A (ja)	1999-07-21
EP0842410A1 (de)	1998-05-20
JP3600247B2 (ja)	2004-12-15
ES2201182T3 (es)	2004-03-16
DE69628651T2 (de)	2004-04-29
US5773299A (en)	1998-06-30
DE69628651D1 (de)	2003-07-17
WO1996033396A1 (en)	1996-10-24

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Publication	Publication Date	Title
DE69628651D1 (de)	2003-07-17	Zusammensetzungen und verfahren für die schnelle analyse von retikulozyten
AU784651B2 (en)	2006-05-18	Reagent and process for the identification and counting of biological cells
US5459073A (en)	1995-10-17	Method and composition for preserving antigens and process for utilizing cytological material produced by same
Crissman et al.	1994	Staining of DNA in live and fixed cells
US5518928A (en)	1996-05-21	Leukocyte differentiation method
US5460797A (en)	1995-10-24	Method for fixing tissues and cells for analysis using oxazolidine compounds
PT95928A (pt)	1991-09-13	Processo para a preparacao de um regente utilizado na determinacao automatica, em citometria de fluxo, de, pelo menos, uma subpopulacao leucocitaria a partir de sangue total
JPH081434B2 (ja)	1996-01-10	多元的細胞識別分析法
AU750108B2 (en)	2002-07-11	Fully automated method and reagent composition therefor for rapid identification and characterization of reticulocytes, erythrocytes and platelets in whole blood
AU699086B2 (en)	1998-11-19	Improved method and reagent composition for performing leukocyte differential counts on fresh and aged whole blood samples
CA2071732A1 (en)	1993-01-30	Method of preparing specimen for classifying and counting leukocytes
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