ATE242883T1 - Verfahren zur bestimmung von blutgerinnungsfaktoren viii und ix - Google Patents
Verfahren zur bestimmung von blutgerinnungsfaktoren viii und ixInfo
- Publication number
- ATE242883T1 ATE242883T1 AT96944747T AT96944747T ATE242883T1 AT E242883 T1 ATE242883 T1 AT E242883T1 AT 96944747 T AT96944747 T AT 96944747T AT 96944747 T AT96944747 T AT 96944747T AT E242883 T1 ATE242883 T1 AT E242883T1
- Authority
- AT
- Austria
- Prior art keywords
- tissue factor
- blood clotting
- clotting factors
- factors viii
- determining blood
- Prior art date
Links
- 239000003114 blood coagulation factor Substances 0.000 title abstract 2
- 102000002262 Thromboplastin Human genes 0.000 abstract 4
- 108010000499 Thromboplastin Proteins 0.000 abstract 4
- 102100026735 Coagulation factor VIII Human genes 0.000 abstract 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 1
- 101000911390 Homo sapiens Coagulation factor VIII Proteins 0.000 abstract 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 abstract 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 235000004279 alanine Nutrition 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001413 amino acids Chemical group 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 235000013922 glutamic acid Nutrition 0.000 abstract 1
- 239000004220 glutamic acid Substances 0.000 abstract 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 abstract 1
- 235000004554 glutamine Nutrition 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/745—Assays involving non-enzymic blood coagulation factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/745—Assays involving non-enzymic blood coagulation factors
- G01N2333/755—Factors VIII, e.g. factor VIII C [AHF], factor VIII Ag [VWF]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
- G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
- G01N2333/9645—Factor IX (3.4.21.22)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US747495P | 1995-11-22 | 1995-11-22 | |
| PCT/US1996/019275 WO1997019357A1 (en) | 1995-11-22 | 1996-11-22 | Assay for blood clotting factors viii and ix |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE242883T1 true ATE242883T1 (de) | 2003-06-15 |
Family
ID=21726391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96944747T ATE242883T1 (de) | 1995-11-22 | 1996-11-22 | Verfahren zur bestimmung von blutgerinnungsfaktoren viii und ix |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0862742B1 (de) |
| JP (1) | JP2000500348A (de) |
| AT (1) | ATE242883T1 (de) |
| AU (1) | AU721720B2 (de) |
| CA (1) | CA2236155A1 (de) |
| DE (1) | DE69628659D1 (de) |
| WO (1) | WO1997019357A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1105475A1 (de) * | 1998-07-15 | 2001-06-13 | Genentech, Inc. | Proteinvarianten von gewebsfaktoren mit erhöhter affinität für koagulationsfaktor fvii/fviia |
| EP1260817A3 (de) | 2001-05-08 | 2002-12-18 | Warner-Lambert Company | Methode zur Direktbestimmung von Koagulationsfaktor VIIa in Plasma |
| JP2007091625A (ja) * | 2005-09-28 | 2007-04-12 | Shino Test Corp | 血液凝固反応促進剤 |
| JP5017622B2 (ja) * | 2005-11-30 | 2012-09-05 | 株式会社シノテスト | 血液凝固反応抑制剤 |
| FR2967781B1 (fr) * | 2010-11-18 | 2019-06-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Determination du pouvoir thrombogene d'immunoglobulines humaines |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US534699A (en) * | 1895-02-26 | Electric resistance-card | ||
| US5504064A (en) * | 1991-04-10 | 1996-04-02 | Oklahoma Medical Research Foundation | Treatment of bleeding with modified tissue factor in combination with an activator of FVII |
| US5346991A (en) * | 1991-06-13 | 1994-09-13 | Genentech, Inc. | Tissue factor mutants useful for the treatment of myocardial infarction and coagulopathic disorders |
| AU663343B2 (en) * | 1991-10-04 | 1995-10-05 | Dade Behring Inc. | Preparation of prothrombin time reagents from recombinant human tissue factor and purified natural and synthetic phospholipids |
| AU674139B2 (en) * | 1992-04-13 | 1996-12-12 | Ortho Diagnostic Systems Inc. | Synthetic phospholipid reagent |
| WO1994007515A1 (en) * | 1992-10-06 | 1994-04-14 | The Scripps Research Institute | Mutant tissue factor lacking factor vii activation activity |
| CA2194369C (en) * | 1994-07-11 | 2004-08-31 | Philip E. Thorpe | Methods and compositions for the specific coagulation of vasculature |
-
1996
- 1996-11-22 EP EP96944747A patent/EP0862742B1/de not_active Expired - Lifetime
- 1996-11-22 AU AU13286/97A patent/AU721720B2/en not_active Ceased
- 1996-11-22 CA CA002236155A patent/CA2236155A1/en not_active Abandoned
- 1996-11-22 WO PCT/US1996/019275 patent/WO1997019357A1/en not_active Ceased
- 1996-11-22 JP JP9519961A patent/JP2000500348A/ja not_active Ceased
- 1996-11-22 DE DE69628659T patent/DE69628659D1/de not_active Expired - Lifetime
- 1996-11-22 AT AT96944747T patent/ATE242883T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0862742A1 (de) | 1998-09-09 |
| CA2236155A1 (en) | 1997-05-29 |
| JP2000500348A (ja) | 2000-01-18 |
| EP0862742B1 (de) | 2003-06-11 |
| WO1997019357A1 (en) | 1997-05-29 |
| AU1328697A (en) | 1997-06-11 |
| DE69628659D1 (de) | 2003-07-17 |
| AU721720B2 (en) | 2000-07-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |