ATE243747T1 - Herstellung von antikörpern - Google Patents

Herstellung von antikörpern

Info

Publication number
ATE243747T1
ATE243747T1 AT92306420T AT92306420T ATE243747T1 AT E243747 T1 ATE243747 T1 AT E243747T1 AT 92306420 T AT92306420 T AT 92306420T AT 92306420 T AT92306420 T AT 92306420T AT E243747 T1 ATE243747 T1 AT E243747T1
Authority
AT
Austria
Prior art keywords
antibodies
production
same
recombinant
prophylaxis
Prior art date
Application number
AT92306420T
Other languages
English (en)
Inventor
James Scott Crowe
Alan Peter Lewis
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27265765&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE243747(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB919115284A external-priority patent/GB9115284D0/en
Priority claimed from GB919116594A external-priority patent/GB9116594D0/en
Priority claimed from GB929206284A external-priority patent/GB9206284D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of ATE243747T1 publication Critical patent/ATE243747T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/106—Picornaviridae (F), e.g. hepatitis A virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT92306420T 1991-07-15 1992-07-14 Herstellung von antikörpern ATE243747T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919115284A GB9115284D0 (en) 1991-07-15 1991-07-15 Production of antibodies
GB919116594A GB9116594D0 (en) 1991-08-01 1991-08-01 Production of antibodies
GB929206284A GB9206284D0 (en) 1992-03-23 1992-03-23 Production of antibodies

Publications (1)

Publication Number Publication Date
ATE243747T1 true ATE243747T1 (de) 2003-07-15

Family

ID=27265765

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92306420T ATE243747T1 (de) 1991-07-15 1992-07-14 Herstellung von antikörpern

Country Status (16)

Country Link
US (1) US5876961A (de)
EP (1) EP0523949B1 (de)
JP (1) JP3502093B2 (de)
KR (1) KR100255717B1 (de)
AT (1) ATE243747T1 (de)
AU (1) AU662752B2 (de)
CA (1) CA2111858A1 (de)
DE (1) DE69233104T2 (de)
ES (1) ES2199216T3 (de)
FI (1) FI940144A0 (de)
HU (1) HU220355B (de)
IE (1) IE922287A1 (de)
IL (1) IL102490A0 (de)
NZ (1) NZ243558A (de)
TW (1) TW373023B (de)
WO (1) WO1993002190A1 (de)

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US20020122807A1 (en) * 1998-07-07 2002-09-05 Dan Michael D. Antigen binding fragments, designated 4B5, that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
US20030180284A1 (en) * 1998-11-05 2003-09-25 Board Of Trustees Of Leland Stanford Junior University Prevention and treatment of HCV infection employing antibodies directed against conformational and linear epitopes
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US6946546B2 (en) 2000-03-06 2005-09-20 Cambridge Antibody Technology Limited Human antibodies against eotaxin
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US20160279239A1 (en) 2011-05-02 2016-09-29 Immunomedics, Inc. Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease
USRE47770E1 (en) 2002-07-18 2019-12-17 Merus N.V. Recombinant production of mixtures of antibodies
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JP5143551B2 (ja) * 2004-07-06 2013-02-13 バイオレン，インク． ユニバーサル抗体のライブラリー
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US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
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US10585098B2 (en) 2009-11-23 2020-03-10 The Johns Hopkins University Optimizing diagnostics for galactofuranose containing antigens
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US9505833B2 (en) 2012-04-20 2016-11-29 Abbvie Inc. Human antibodies that bind human TNF-alpha and methods of preparing the same
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US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
HK1211981A1 (en) 2012-09-02 2016-06-03 Abbvie Inc. Methods to control protein heterogeneity
HRP20181717T1 (hr) 2012-09-27 2018-12-28 Merus N.V. Bispecifična igg protutijela kao aktivatori t stanice
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
WO2014159579A1 (en) 2013-03-14 2014-10-02 Abbvie Inc. MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
JP6205175B2 (ja) * 2013-05-16 2017-10-04 株式会社Ｒｅｓｖｏ 精神・神経疾患バイオマーカー
WO2015051293A2 (en) 2013-10-04 2015-04-09 Abbvie, Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
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WO2015095195A1 (en) 2013-12-16 2015-06-25 The Johns Hopkins University Interferon-gamma release assays for diagnosis of invasive fungal infections
ES2816624T3 (es) 2014-02-28 2021-04-05 Merus Nv Anticuerpos que se unen a EGFR y ERBB3
HRP20250041T1 (hr) 2014-02-28 2025-03-14 Merus N.V. Antitijelo koje veže erbb-2 i erbb-3
ES2693596T3 (es) 2015-07-10 2018-12-12 Merus N.V. Anticuerpo que se une a CD3 humano
KR20250157457A (ko) 2015-10-23 2025-11-04 메뤼스 엔.페. 암 성장을 억제하는 결합 분자
WO2018182422A1 (en) 2017-03-31 2018-10-04 Merus N.V. Erbb-2 and erbb3 binding bispecific antibodies for use in the treatment f cells that have an nrg1 fusion gene
US10799597B2 (en) 2017-04-03 2020-10-13 Immunomedics, Inc. Subcutaneous administration of antibody-drug conjugates for cancer therapy
CN111148764B (zh) 2017-05-17 2025-08-12 美勒斯公司 用于乳腺癌的ErbB-2/ErbB-3双特异性抗体与内分泌治疗的组合
PL3665198T3 (pl) 2017-08-09 2025-06-09 Merus N.V. Przeciwciała wiążące egfr i cmet
TW201930351A (zh) 2017-10-06 2019-08-01 日商小野藥品工業股份有限公司 雙特異性抗體
TWI849895B (zh) 2018-02-09 2024-07-21 日商小野藥品工業股份有限公司 雙特異性抗體
TWI862565B (zh) 2019-04-04 2024-11-21 日商小野藥品工業股份有限公司 雙特異性抗體
EP3998081A4 (de) 2019-07-05 2023-07-12 Ono Pharmaceutical Co., Ltd. Behandlung von hämatologischem krebs mit pd-1/cd3-protein mit doppelter spezifität
EP4008348A4 (de) 2019-07-30 2023-11-15 ONO Pharmaceutical Co., Ltd. Bispezifische antikörper
JP7771749B2 (ja) 2019-08-08 2025-11-18 小野薬品工業株式会社 二重特異性タンパク質
WO2024043227A1 (ja) 2022-08-23 2024-02-29 小野薬品工業株式会社 二重特異性抗体

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Also Published As

Publication number Publication date
FI940144A7 (fi) 1994-01-12
IE922287A1 (en) 1993-01-27
AU662752B2 (en) 1995-09-14
NZ243558A (en) 1994-06-27
CA2111858A1 (en) 1993-02-04
TW373023B (en) 1999-11-01
JP3502093B2 (ja) 2004-03-02
HU220355B (hu) 2001-12-28
JPH07502882A (ja) 1995-03-30
AU2279892A (en) 1993-02-23
FI940144L (fi) 1994-01-12
DE69233104T2 (de) 2004-05-13
FI940144A0 (fi) 1994-01-12
KR100255717B1 (ko) 2000-05-01
HU9400110D0 (en) 1994-05-30
IL102490A0 (en) 1993-01-14
ES2199216T3 (es) 2004-02-16
DE69233104D1 (de) 2003-07-31
WO1993002190A1 (en) 1993-02-04
EP0523949A1 (de) 1993-01-20
EP0523949B1 (de) 2003-06-25
US5876961A (en) 1999-03-02
HUT69798A (en) 1995-09-28

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Legal Events

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