ATE244218T1 - Verfahren zur herstellung von beta- lactamderivaten - Google Patents
Verfahren zur herstellung von beta- lactamderivatenInfo
- Publication number
- ATE244218T1 ATE244218T1 AT96904294T AT96904294T ATE244218T1 AT E244218 T1 ATE244218 T1 AT E244218T1 AT 96904294 T AT96904294 T AT 96904294T AT 96904294 T AT96904294 T AT 96904294T AT E244218 T1 ATE244218 T1 AT E244218T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- beta
- lactam
- substituent
- hydrogen atom
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 150000003952 β-lactams Chemical class 0.000 title 1
- -1 beta -lactam halide compound Chemical class 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000001424 substituent group Chemical group 0.000 abstract 3
- 125000005282 allenyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000006244 carboxylic acid protecting group Chemical group 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 229910001507 metal halide Inorganic materials 0.000 abstract 1
- 150000005309 metal halides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP07948995A JP3775820B2 (ja) | 1995-03-10 | 1995-03-10 | ハロゲン化β−ラクタム化合物の製造法 |
| PCT/JP1996/000489 WO1996028421A1 (en) | 1995-03-10 | 1996-03-01 | PROCESS FOR PRODUCING HALOGENATED β-LACTAM COMPOUNDS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE244218T1 true ATE244218T1 (de) | 2003-07-15 |
Family
ID=13691324
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96904294T ATE244218T1 (de) | 1995-03-10 | 1996-03-01 | Verfahren zur herstellung von beta- lactamderivaten |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6011151A (de) |
| EP (1) | EP0759427B1 (de) |
| JP (1) | JP3775820B2 (de) |
| AT (1) | ATE244218T1 (de) |
| DE (1) | DE69628887T2 (de) |
| WO (1) | WO1996028421A1 (de) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4918832A (de) * | 1972-06-19 | 1974-02-19 | ||
| US4011216A (en) * | 1975-04-11 | 1977-03-08 | Bristol-Myers Company | Δ2,3-0-2-Isocephem-4-carboxylic acid and derivatives thereof as antibacterial agents |
| US4013648A (en) * | 1975-07-23 | 1977-03-22 | Bristol-Myers Company | Δ2,3 -0-2-Isocephem-4-carboxylic acid and derivatives as antibacterial agents |
| DE3687870T2 (de) * | 1985-09-09 | 1993-08-19 | Otsuka Pharma Co Ltd | 2-oxa-isocephemverbindungen, sie enthaltende zusammensetzungen und verfahren zu deren herstellung. |
| JP3195371B2 (ja) * | 1991-03-11 | 2001-08-06 | 大塚化学株式会社 | セフエム誘導体の製造法 |
| US5196530A (en) * | 1991-03-11 | 1993-03-23 | Otsuka Kagaku Kabushiki Kaisha | Process for preparing 2-exo-methylenepenam derivatives |
| JP3224279B2 (ja) * | 1992-07-27 | 2001-10-29 | 大塚化学株式会社 | セフエム化合物の製造法 |
| JPH08245635A (ja) * | 1995-03-10 | 1996-09-24 | Otsuka Chem Co Ltd | ２−イソセフェム誘導体の製造法 |
-
1995
- 1995-03-10 JP JP07948995A patent/JP3775820B2/ja not_active Expired - Fee Related
-
1996
- 1996-03-01 DE DE69628887T patent/DE69628887T2/de not_active Expired - Fee Related
- 1996-03-01 AT AT96904294T patent/ATE244218T1/de not_active IP Right Cessation
- 1996-03-01 WO PCT/JP1996/000489 patent/WO1996028421A1/ja not_active Ceased
- 1996-03-01 EP EP96904294A patent/EP0759427B1/de not_active Expired - Lifetime
- 1996-03-01 US US08/732,444 patent/US6011151A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996028421A1 (en) | 1996-09-19 |
| US6011151A (en) | 2000-01-04 |
| JP3775820B2 (ja) | 2006-05-17 |
| DE69628887T2 (de) | 2004-04-15 |
| JPH08245574A (ja) | 1996-09-24 |
| EP0759427A1 (de) | 1997-02-26 |
| EP0759427B1 (de) | 2003-07-02 |
| EP0759427A4 (de) | 1998-07-08 |
| DE69628887D1 (de) | 2003-08-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0759427 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |