ATE244279T1 - Verfahren zur synthese von phthalocyaninverbindungen - Google Patents

Verfahren zur synthese von phthalocyaninverbindungen

Info

Publication number
ATE244279T1
ATE244279T1 AT97945416T AT97945416T ATE244279T1 AT E244279 T1 ATE244279 T1 AT E244279T1 AT 97945416 T AT97945416 T AT 97945416T AT 97945416 T AT97945416 T AT 97945416T AT E244279 T1 ATE244279 T1 AT E244279T1
Authority
AT
Austria
Prior art keywords
ligand
displacing
phthalocyanine
cl3ccoo
central silicon
Prior art date
Application number
AT97945416T
Other languages
English (en)
Inventor
Ying-Syi Li
Malcolm E Kenney
Original Assignee
Univ Cleveland Hospitals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cleveland Hospitals filed Critical Univ Cleveland Hospitals
Application granted granted Critical
Publication of ATE244279T1 publication Critical patent/ATE244279T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B47/00—Porphines; Azaporphines
    • C09B47/04—Phthalocyanines abbreviation: Pc
    • C09B47/30—Metal-free phthalocyanines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B47/00—Porphines; Azaporphines
    • C09B47/04—Phthalocyanines abbreviation: Pc
    • C09B47/08—Preparation from other phthalocyanine compounds, e.g. cobaltphthalocyanineamine complex

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT97945416T 1996-10-01 1997-09-30 Verfahren zur synthese von phthalocyaninverbindungen ATE244279T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/724,347 US5763602A (en) 1996-10-01 1996-10-01 Methods of syntheses of phthalocyanine compounds
PCT/US1997/017690 WO1998014521A1 (en) 1996-10-01 1997-09-30 Novel methods of syntheses of phthalocyanine compounds

Publications (1)

Publication Number Publication Date
ATE244279T1 true ATE244279T1 (de) 2003-07-15

Family

ID=24910068

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97945416T ATE244279T1 (de) 1996-10-01 1997-09-30 Verfahren zur synthese von phthalocyaninverbindungen

Country Status (9)

Country Link
US (1) US5763602A (de)
EP (1) EP1023399B1 (de)
JP (1) JP2001506584A (de)
KR (1) KR20000036186A (de)
AT (1) ATE244279T1 (de)
AU (1) AU4662697A (de)
CA (1) CA2267389A1 (de)
DE (1) DE69723322T2 (de)
WO (1) WO1998014521A1 (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6322980B1 (en) * 1999-04-30 2001-11-27 Aclara Biosciences, Inc. Single nucleotide detection using degradation of a fluorescent sequence
US20030207300A1 (en) * 2000-04-28 2003-11-06 Matray Tracy J. Multiplex analytical platform using molecular tags
US7771929B2 (en) * 2000-04-28 2010-08-10 Monogram Biosciences, Inc. Tag library compounds, compositions, kits and methods of use
US7537938B2 (en) * 2000-04-28 2009-05-26 Monogram Biosciences, Inc. Biomarker detection in circulating cells
US7160735B2 (en) * 2000-04-28 2007-01-09 Monogram Biosciences, Inc. Tagged microparticle compositions and methods
CZ20033143A3 (en) * 2001-05-21 2004-04-14 Aclara Biosciences, Inc. Methods and compositions for analyzing proteins
US7041459B2 (en) 2001-05-21 2006-05-09 Monogram Biosciences, Inc. Analyzing phosphorylated proteins
WO2002096913A1 (en) * 2001-05-25 2002-12-05 Gentian As Substituted di(hydroxy/alkoxy)silicon phthalocyanines and their uses
AU2002344221A1 (en) * 2001-05-26 2002-12-09 Aclara Biosciences, Inc. Catalytic amplification of multiplexed assay signals
US20040229380A1 (en) * 2002-05-21 2004-11-18 Po-Ying Chan-Hui ErbB heterodimers as biomarkers
ATE442589T1 (de) 2002-07-25 2009-09-15 Aclara Biosciences Inc Nachweis der rezeptoroligomerisierung
US20040091850A1 (en) * 2002-11-08 2004-05-13 Travis Boone Single cell analysis of membrane molecules
US7402398B2 (en) * 2003-07-17 2008-07-22 Monogram Biosciences, Inc. Measuring receptor homodimerization
EP1673399B1 (de) * 2003-08-11 2017-04-05 Monogram BioSciences, Inc. Nachweis und erstellung des profils eines molekularen komplexes
CA2543830A1 (en) * 2003-10-27 2005-05-19 Monogram Biosciences, Inc. Detecting human anti-therapeutic antibodies
US7939267B2 (en) * 2004-11-04 2011-05-10 Laboratory Corporation Of America Holdings Detection of activation of endothelial cells as surrogate marker for angiogenesis
WO2008098100A2 (en) * 2007-02-07 2008-08-14 Perscitus Biosciences, Llc Detection of molecule proximity
WO2009086197A1 (en) * 2007-12-20 2009-07-09 Monogram Biosciences, Inc. Her-2 diagnostic methods
EP2438442B1 (de) 2008-12-01 2017-08-09 Laboratory Corporation of America Holdings Verfahren und tests zur messung von p95 und/oder p95-komlexen in einer probe und für p95 spezifische antikörper
US20120295259A1 (en) 2011-05-19 2012-11-22 Laboratory Corporation Of America Holdings Methods for Determining the Likelihood of Survival and for Predicting Likelihood of Metastasis in Cancer Patients
BRPI1007321A2 (en) 2009-01-15 2018-07-10 Laboratory Corporation Of America Holdings methods for measuring and / or quantifying the presence and / or amount of her-3 or her-3 in a complex in a patient sample, and to determine if an individual with cancer is likely to respond to treatment with a targeted therapy. and antibody.
WO2010095033A1 (en) 2009-02-20 2010-08-26 Perkinelmer Biosignal, Inc. Multiplex assay methods and compositions
US8440641B2 (en) * 2009-03-20 2013-05-14 Case Western Reserve University Phthalocyanine salt formulations
WO2013020067A1 (en) 2011-08-03 2013-02-07 Sun Chemical Corporation Phthalocyanine synthesis
KR101471613B1 (ko) * 2013-02-07 2014-12-12 광주과학기술원 고분자 태양전지 및 이의 제조방법
CA2908515A1 (en) 2013-04-05 2014-10-09 Laboratory Corporation Of America Holdings Systems and methods for facilitating diagnosis, prognosis and treatment of cancer based on detection of her3 activation
US10451614B2 (en) 2016-03-15 2019-10-22 Laboratory Corporation Of America Holdings Methods of assessing protein interactions between cells
US20190227082A1 (en) 2016-07-06 2019-07-25 Prothena Biosciences Limited Assay for detecting total and s129 phosphorylated alpha-synuclein
CA3045944A1 (en) 2016-12-07 2018-06-14 Progenity, Inc. Gastrointestinal tract detection methods, devices and systems
WO2018112223A1 (en) 2016-12-14 2018-06-21 Progenity Inc. Treatment of a disease of the gastrointestinal tract with a tlr modulator
US11523772B2 (en) 2016-12-14 2022-12-13 Biora Therapeutics, Inc. Treatment of a disease of the gastrointestinal tract with an immunosuppressant
US20200315540A1 (en) 2016-12-14 2020-10-08 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an il-1 inhibitor
EP3554345A1 (de) 2016-12-14 2019-10-23 Progenity, Inc. Behandlung von erkrankungen des gastrointestinaltraktes mit einem smad7-inhibitor
AU2017378393B2 (en) 2016-12-14 2023-03-09 Bt Bidco, Inc. Treatment of a disease of the gastrointestinal tract with a TNF inhibitor
CA3045666A1 (en) 2016-12-14 2018-06-21 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a jak inhibitor and devices
CN116712540A (zh) 2016-12-14 2023-09-08 比奥拉治疗股份有限公司 使用整联蛋白抑制剂治疗胃肠道疾病
WO2018112232A1 (en) 2016-12-14 2018-06-21 Progenity Inc. Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor released using an ingestible device
WO2018112237A1 (en) 2016-12-14 2018-06-21 Progenity Inc. Treatment of a disease of the gastrointestinal tract with an il-6r inhibitor
CA3045310A1 (en) 2016-12-14 2018-06-21 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor
CA3054632A1 (en) 2017-03-30 2018-10-04 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
WO2018183932A1 (en) 2017-03-30 2018-10-04 Progenity Inc. Treatment of a disease of the gastrointestinal tract with a il-13 inhibitor
CA3054156A1 (en) 2017-03-30 2018-10-04 Progenity Inc. Treatment of a disease of the gastrointestinal tract with il-10 or an il-10 agonist
WO2018183941A2 (en) 2017-03-30 2018-10-04 Progenity Inc. Treatment of a disease of the gastrointestinal tract with live biotherapeutics
WO2018183934A1 (en) 2017-03-30 2018-10-04 Progenity Inc. Treatment of a disease of the gastrointestinal tract with a chst15 inhibitor
WO2019036363A1 (en) 2017-08-14 2019-02-21 Progenity Inc. TREATMENT OF GASTROINTESTINAL TRACT DISEASE WITH GLATIRAMER OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
WO2019147824A1 (en) 2018-01-26 2019-08-01 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a pde4 inhibitor
WO2019232295A1 (en) 2018-06-01 2019-12-05 Progenity, Inc. Devices and systems for gastrointestinal microbiome detection and manipulation
BR112022020521A2 (pt) 2020-04-10 2023-03-07 Rakuten Medical Inc Compostos de corante ftalocianina, conjugados e métodos de uso dos mesmos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927735A (en) * 1987-01-07 1990-05-22 Hitachi Chemical Company, Ltd. Novel naphthalocyanine dye, method for preparing the same, and optical information recording medium employing the same
ATE206395T1 (de) * 1990-05-15 2001-10-15 Hyperion Inc Fluoreszierende porphyrin- und fluoreszierende phthalocyanin-polyethylenglykol-, polyol- und saccharidderivate als fluoreszierende sonden
US5166197A (en) * 1990-07-17 1992-11-24 Kenney Malcolm E Phthalocyanine photosensitizers for photodynamic therapy
US5484778C1 (en) * 1990-07-17 2001-05-08 Univ Cleveland Hospitals Phthalocynine photosensitizers for photodynamic therapy and methods for their use
TW235298B (de) * 1992-02-27 1994-12-01 Ciba Geigy

Also Published As

Publication number Publication date
AU4662697A (en) 1998-04-24
US5763602A (en) 1998-06-09
DE69723322T2 (de) 2004-05-27
EP1023399A4 (de) 2002-02-27
EP1023399A1 (de) 2000-08-02
EP1023399B1 (de) 2003-07-02
JP2001506584A (ja) 2001-05-22
WO1998014521A1 (en) 1998-04-09
CA2267389A1 (en) 1998-04-09
KR20000036186A (ko) 2000-06-26
DE69723322D1 (de) 2003-08-07

Similar Documents

Publication Publication Date Title
DE69723322D1 (de) Verfahren zur synthese von phthalocyaninverbindungen
Brookhart et al. Enantioselective cyclopropane synthesis using the chiral carbene complexes (SFeSC)-and (RFeSC)-(C5H5)(CO)(Ph2R* P) Fe: CHCH3+ (R*=(S)-2-methylbutyl). Role of metal vs. ligand chirality in the optical induction
DE59108707D1 (de) Verfahren zur Herstellung von Oxetanonen
DE60005143D1 (de) Herstellung von iodixanol
DE69801764D1 (de) Verfahren zur herstellung von citalopram
DE69103265D1 (de) Verfahren zur stereoselektiven herstellung von phenylisoserinderivaten.
Moody et al. Stereospecific synthesis of 4-alkylglutamates and 4-alkylprolines
DE60009910D1 (de) Verfahren zur herstellung von zsm-5 und zsm-11
DE69207429D1 (de) Verfahren zur herstellung von substituierten piperidinen
ATE174601T1 (de) Verfahren zur herstellung von bisnoraldehyden aus bisnoralkohol
ATE160351T1 (de) Verfahren zur herstellung von 7-trialkylsilyl baccatin iii
ATE359272T1 (de) Verfahren zur herstellung von 3-hydroxy-n-1,6-
ATE270301T1 (de) Verfahren zur herstellung von modifizierten p- chiralen nucleotid-analoga
Jackson et al. An antibody-catalyzed cis-trans isomerization reaction
DE69820481D1 (de) Verfahren zur herstellung von cholecalciferol-derivaten und zwischenverbindungen
DE60015563D1 (de) Verfahren zur herstellung von benzoperhydroisoindolen
RU2219161C2 (ru) Способ синтеза таксанов
RU94046247A (ru) Способ получения практически беспыльного гранулята из тетрагидро-3,5-диметил-1,3,5-тиадиазин-2-тиона
KR840006656A (ko) 1,3,4,6,7,11b-헥사하이드로-7-아릴-2H-피라지노[2,1-α]이소퀴놀린의 제조방법
ATE299851T1 (de) Verfahren zur herstellung von zwischenprodukten
DE69513408D1 (de) Ein verbessertes verfahren für die herstellung von seitenketten-derivaten von cyclohexapeptidyl-lipopeptiden
ATE236875T1 (de) Verfahren zur herstellung von cyclischen lactamen
ATE188694T1 (de) Verfahren zur herstellung von benzopyranderivaten
ATE384730T1 (de) Verfahren zur herstellung von palladium(0)- haltigen verbindungen
ATE167469T1 (de) Verfahren zur herstellung von selegilin

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties