ATE244303T1 - IN SICH GESCHLOSSENDE ßSENS-ß UND ßANTISENSEß- OLIGONUKLEOTIDE UND DEREN VERWENDUNGEN - Google Patents

IN SICH GESCHLOSSENDE ßSENS-ß UND ßANTISENSEß- OLIGONUKLEOTIDE UND DEREN VERWENDUNGEN

Info

Publication number
ATE244303T1
ATE244303T1 AT92910423T AT92910423T ATE244303T1 AT E244303 T1 ATE244303 T1 AT E244303T1 AT 92910423 T AT92910423 T AT 92910423T AT 92910423 T AT92910423 T AT 92910423T AT E244303 T1 ATE244303 T1 AT E244303T1
Authority
AT
Austria
Prior art keywords
oligonucleotides
ßsens
ßantisensß
self
contained
Prior art date
Application number
AT92910423T
Other languages
English (en)
Inventor
Marta Blumenfeld
Pascal Brandys
Auriol Luc D
Marc Vasseur
Original Assignee
Genset Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genset Sa filed Critical Genset Sa
Application granted granted Critical
Publication of ATE244303T1 publication Critical patent/ATE244303T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/13Decoys
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/50Physical structure
    • C12N2310/53Physical structure partially self-complementary or closed

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT92910423T 1991-04-25 1992-04-24 IN SICH GESCHLOSSENDE ßSENS-ß UND ßANTISENSEß- OLIGONUKLEOTIDE UND DEREN VERWENDUNGEN ATE244303T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9105114A FR2675803B1 (fr) 1991-04-25 1991-04-25 Oligonucleotides fermes, antisens et sens et leurs applications.
PCT/FR1992/000370 WO1992019732A1 (fr) 1991-04-25 1992-04-24 Oligonucleotides fermes, antisens et sens, et leurs applications

Publications (1)

Publication Number Publication Date
ATE244303T1 true ATE244303T1 (de) 2003-07-15

Family

ID=9412249

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92910423T ATE244303T1 (de) 1991-04-25 1992-04-24 IN SICH GESCHLOSSENDE ßSENS-ß UND ßANTISENSEß- OLIGONUKLEOTIDE UND DEREN VERWENDUNGEN

Country Status (11)

Country Link
US (1) US6369038B1 (de)
EP (2) EP0581848B1 (de)
JP (1) JPH06506834A (de)
AT (1) ATE244303T1 (de)
AU (1) AU660679B2 (de)
CA (1) CA2102229A1 (de)
DE (1) DE69233117T2 (de)
DK (1) DK0581848T3 (de)
ES (1) ES2199936T3 (de)
FR (1) FR2675803B1 (de)
WO (1) WO1992019732A1 (de)

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FR2710846B1 (fr) 1993-10-04 1995-12-22 Rhone Poulenc Rorer Sa Compositions pharmaceutiques et leur utilisation, notamment dans le traitement des maladies neurogénératives.
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Also Published As

Publication number Publication date
FR2675803B1 (fr) 1996-09-06
JPH06506834A (ja) 1994-08-04
DE69233117D1 (de) 2003-08-07
EP0581848A1 (de) 1994-02-09
EP0572287A3 (de) 1994-01-12
US6369038B1 (en) 2002-04-09
DE69233117T2 (de) 2004-04-15
FR2675803A1 (fr) 1992-10-30
CA2102229A1 (fr) 1992-10-26
DK0581848T3 (da) 2003-10-27
EP0572287A2 (de) 1993-12-01
ES2199936T3 (es) 2004-03-01
AU660679B2 (en) 1995-07-06
AU1759692A (en) 1992-12-21
WO1992019732A1 (fr) 1992-11-12
EP0581848B1 (de) 2003-07-02

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