ATE245025T1 - Aerosolzusammensetzungen mit prilocaine und fluorokohlenwasserstoff - Google Patents

Aerosolzusammensetzungen mit prilocaine und fluorokohlenwasserstoff

Info

Publication number: ATE245025T1
Authority: AT; Austria
Prior art keywords: prilocaine; hfc; pharmaceutical; propellants; aerosol compositions
Prior art date: 1995-03-17

Application number

AT96902844T

Other languages

English (en)

Inventor

Richard A Dr Henry

Original Assignee

Lynchris Pharm Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-17

Filing date

1996-03-04

Publication date

2003-08-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27410659&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE245025(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-03-17 Priority claimed from US08/405,930 external-priority patent/US5593661A/en

1995-03-24 Priority claimed from US08/408,877 external-priority patent/US5534242A/en

1996-03-04 Application filed by Lynchris Pharm Ltd filed Critical Lynchris Pharm Ltd

2003-08-15 Application granted granted Critical

2003-08-15 Publication of ATE245025T1 publication Critical patent/ATE245025T1/de

Links

MVFGUOIZUNYYSO-UHFFFAOYSA-N prilocaine Chemical compound CCCNC(C)C(=O)NC1=CC=CC=C1C MVFGUOIZUNYYSO-UHFFFAOYSA-N 0.000 title abstract 7
239000000203 mixture Substances 0.000 title abstract 4
239000000443 aerosol Substances 0.000 title abstract 3
229960001807 prilocaine Drugs 0.000 title abstract 3
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 title 1
NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 title 1
239000001257 hydrogen Substances 0.000 title 1
239000003380 propellant Substances 0.000 abstract 3
102000004190 Enzymes Human genes 0.000 abstract 2
108090000790 Enzymes Proteins 0.000 abstract 2
BLFLLBZGZJTVJG-UHFFFAOYSA-N benzocaine Chemical compound CCOC(=O)C1=CC=C(N)C=C1 BLFLLBZGZJTVJG-UHFFFAOYSA-N 0.000 abstract 2
ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 abstract 2
229940088598 enzyme Drugs 0.000 abstract 2
ZKMNUMMKYBVTFN-HNNXBMFYSA-N (S)-ropivacaine Chemical compound CCCN1CCCC[C@H]1C(=O)NC1=C(C)C=CC=C1C ZKMNUMMKYBVTFN-HNNXBMFYSA-N 0.000 abstract 1
YFMFNYKEUDLDTL-UHFFFAOYSA-N 1,1,1,2,3,3,3-heptafluoropropane Chemical compound FC(F)(F)C(F)C(F)(F)F YFMFNYKEUDLDTL-UHFFFAOYSA-N 0.000 abstract 1
LVGUZGTVOIAKKC-UHFFFAOYSA-N 1,1,1,2-tetrafluoroethane Chemical compound FCC(F)(F)F LVGUZGTVOIAKKC-UHFFFAOYSA-N 0.000 abstract 1
LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 abstract 1
ZGXJTSGNIOSYLO-UHFFFAOYSA-N 88755TAZ87 Chemical compound NCC(=O)CCC(O)=O ZGXJTSGNIOSYLO-UHFFFAOYSA-N 0.000 abstract 1
VTUSIVBDOCDNHS-UHFFFAOYSA-N Etidocaine Chemical compound CCCN(CC)C(CC)C(=O)NC1=C(C)C=CC=C1C VTUSIVBDOCDNHS-UHFFFAOYSA-N 0.000 abstract 1
NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
239000000556 agonist Substances 0.000 abstract 1
229960002749 aminolevulinic acid Drugs 0.000 abstract 1
230000003444 anaesthetic effect Effects 0.000 abstract 1
239000003242 anti bacterial agent Substances 0.000 abstract 1
229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
239000002260 anti-inflammatory agent Substances 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
230000002421 anti-septic effect Effects 0.000 abstract 1
229940088710 antibiotic agent Drugs 0.000 abstract 1
229940125715 antihistaminic agent Drugs 0.000 abstract 1
239000000739 antihistaminic agent Substances 0.000 abstract 1
229940064004 antiseptic throat preparations Drugs 0.000 abstract 1
-1 antiseptics Substances 0.000 abstract 1
229960005274 benzocaine Drugs 0.000 abstract 1
229940124630 bronchodilator Drugs 0.000 abstract 1
239000000168 bronchodilator agent Substances 0.000 abstract 1
229960003150 bupivacaine Drugs 0.000 abstract 1
229960002023 chloroprocaine Drugs 0.000 abstract 1
VDANGULDQQJODZ-UHFFFAOYSA-N chloroprocaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1Cl VDANGULDQQJODZ-UHFFFAOYSA-N 0.000 abstract 1
229960003920 cocaine Drugs 0.000 abstract 1
239000000470 constituent Substances 0.000 abstract 1
239000000645 desinfectant Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229960003976 etidocaine Drugs 0.000 abstract 1
229940088597 hormone Drugs 0.000 abstract 1
239000005556 hormone Substances 0.000 abstract 1
229960004194 lidocaine Drugs 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
229960002409 mepivacaine Drugs 0.000 abstract 1
INWLQCZOYSRPNW-UHFFFAOYSA-N mepivacaine Chemical compound CN1CCCCC1C(=O)NC1=C(C)C=CC=C1C INWLQCZOYSRPNW-UHFFFAOYSA-N 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
229960001802 phenylephrine Drugs 0.000 abstract 1
SONNWYBIRXJNDC-VIFPVBQESA-N phenylephrine Chemical compound CNC[C@H](O)C1=CC=CC(O)=C1 SONNWYBIRXJNDC-VIFPVBQESA-N 0.000 abstract 1
229960004919 procaine Drugs 0.000 abstract 1
MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
108091006082 receptor inhibitors Proteins 0.000 abstract 1
229960001549 ropivacaine Drugs 0.000 abstract 1
230000003381 solubilizing effect Effects 0.000 abstract 1
150000003431 steroids Chemical class 0.000 abstract 1
230000002227 vasoactive effect Effects 0.000 abstract 1
239000005526 vasoconstrictor agent Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/124—Aerosols; Foams characterised by the propellant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Otolaryngology (AREA)
Pain & Pain Management (AREA)
Emergency Medicine (AREA)
Anesthesiology (AREA)
Pulmonology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Cosmetics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT96902844T 1995-03-17 1996-03-04 Aerosolzusammensetzungen mit prilocaine und fluorokohlenwasserstoff ATE245025T1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US08/405,930 US5593661A (en)	1993-03-29	1995-03-17	Lidocaine aerosol anaesthetic
US08/408,877 US5534242A (en)	1994-05-02	1995-03-24	Lidocaine-vasoconstrictor aerosol preparation
US08/435,812 US5589156A (en)	1994-05-02	1995-05-05	Prilocaine and hydrofluourocarbon aerosol preparations
PCT/CA1996/000122 WO1996029066A1 (en)	1995-03-17	1996-03-04	Prilocaine and hydrofluorocarbon aerosol preparations

Publications (1)

Publication Number	Publication Date
ATE245025T1 true ATE245025T1 (de)	2003-08-15

Family

ID=27410659

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96902844T ATE245025T1 (de)	1995-03-17	1996-03-04	Aerosolzusammensetzungen mit prilocaine und fluorokohlenwasserstoff

Country Status (13)

Country	Link
US (1)	US5589156A (de)
EP (1)	EP0814793B1 (de)
JP (1)	JP4117707B2 (de)
CN (1)	CN1149080C (de)
AT (1)	ATE245025T1 (de)
AU (1)	AU710600B2 (de)
BR (1)	BR9607988A (de)
DE (1)	DE69629109T2 (de)
DK (1)	DK0814793T3 (de)
ES (1)	ES2203676T3 (de)
LU (1)	LU92402I2 (de)
PT (1)	PT814793E (de)
WO (1)	WO1996029066A1 (de)

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US5593661A (en) *	1993-03-29	1997-01-14	Henry; Richard A.	Lidocaine aerosol anaesthetic
EP0759744B1 (de) *	1994-05-13	2001-10-17	Aradigm Corporation	Ein narkotikum enthaltende aerosolformulierung
US6013245A (en) *	1995-01-26	2000-01-11	Glaxo Group Limited	Aerosol formulation containing beclomethasone dipropionate and 1,1,1,2,3,3,3-heptafluoro-n-propane as propellant
US5955098A (en) *	1996-04-12	1999-09-21	Flemington Pharmaceutical Corp.	Buccal non polar spray or capsule
US6200288B1 (en)	1997-08-26	2001-03-13	Queen's University At Kingston	Everting toroid device for insertion into a body cavity
US5954688A (en) *	1997-08-26	1999-09-21	Queen's University At Kingston	Everting toroid device for delivering a drug into a body cavity
GB2332372B (en) *	1997-12-08	2002-08-14	Minnesota Mining & Mfg	Pharmaceutical aerosol compositions
US6423298B2 (en)	1998-06-18	2002-07-23	Boehringer Ingelheim Pharmaceuticals, Inc.	Pharmaceutical formulations for aerosols with two or more active substances
ATE253896T1 (de) *	1998-06-18	2003-11-15	Boehringer Ingelheim Pharma	Zwei oder mehrere wirkstoffe enthaltende pharmazeutische aerosolformulierungen
DE19827178A1 (de) *	1998-06-18	2000-04-27	Boehringer Ingelheim Pharma	Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen
US6235265B1 (en)	1998-10-28	2001-05-22	Alliedsignal Inc.	Evaporative coolant for topical anesthesia comprising hydrofluorocarbons and/or hydrochlorofluorocarbons
WO2001045678A2 (de) *	1999-12-21	2001-06-28	Id Pharma Gmbh	Arzneimittel, verfahren zu dessen herstellung und dessen verwendung
GB0015361D0 (en) *	2000-06-22	2000-08-16	Pharmasol Ltd	Improvements in pharmaceutical compositions
CN100496608C (zh) *	2001-03-30	2009-06-10	洁垢技术有限公司	药用气溶胶制剂
US20040241103A1 (en) *	2002-09-10	2004-12-02	3M Innovative Properties Company	Pharmaceutical aerosol compositions
US20040076671A1 (en) *	2002-10-21	2004-04-22	Aletha Tippett	Methods and compositions for topical wound treatment
US7785584B2 (en) *	2003-08-13	2010-08-31	Healthpoint, Ltd.	Ointment wound spray
US7105006B2 (en) *	2003-08-15	2006-09-12	Stat Medical Devices, Inc.	Adjustable lancet device and method
WO2005032521A2 (en) *	2003-10-02	2005-04-14	Collegium Pharmaceutical, Inc.	Non-flammable topical anesthetic liquid aerosols
US20060188449A1 (en) *	2003-10-03	2006-08-24	Jane Hirsh	Topical aerosol foams
WO2005115336A2 (en) *	2004-05-15	2005-12-08	Collegium Pharmaceutical, Inc.	Sprayable formulations for the treatment of acute inflammatory skin conditions
US8741333B2 (en)	2004-06-07	2014-06-03	Nuvo Research Inc.	Compositions and methods for treating dermatitis or psoriasis
US20070196452A1 (en) *	2004-06-07	2007-08-23	Jie Zhang	Flux-enabling compositions and methods for dermal delivery of drugs
US20070196323A1 (en) *	2004-06-07	2007-08-23	Jie Zhang	Polyvinyl alcohol-containing compositions and methods for dermal delivery of drugs
US20070189978A1 (en) *	2004-06-07	2007-08-16	Jie Zhang	Compositions and methods for dermally treating musculoskeletal pain
US20080019927A1 (en) *	2004-06-07	2008-01-24	Jie Zhang	Compositions and methods for dermally treating neuropathy with minoxidil
US20070196457A1 (en) *	2004-06-07	2007-08-23	Jie Zhang	Two or more volatile solvent-containing compositions and methods for dermal delivery of drugs
US8741332B2 (en) *	2004-06-07	2014-06-03	Nuvo Research Inc.	Compositions and methods for dermally treating neuropathic pain
US20070196293A1 (en) *	2004-06-07	2007-08-23	Jie Zhang	Compositions and methods for treating photo damaged skin
US8907153B2 (en)	2004-06-07	2014-12-09	Nuvo Research Inc.	Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same
US20070190124A1 (en) *	2004-06-07	2007-08-16	Jie Zhang	Two or more solidifying agent-containing compositions and methods for dermal delivery of drugs
US20070189977A1 (en) *	2004-06-07	2007-08-16	Jie Zhang	Spray-on formulations and methods for dermal delivery of drugs
US20070280972A1 (en) *	2006-04-25	2007-12-06	Zars, Inc.	Adhesive solid gel-forming formulations for dermal drug delivery
US9265898B2 (en) *	2007-09-12	2016-02-23	Wolfe Tory Medical, Inc.	Applicator for oropharyngeal anesthetic
US20090093547A1 (en) *	2007-10-09	2009-04-09	Sciele Pharma, Inc.	Compositions and Methods for Treating Premature Ejaculation
FR2927256B1 (fr) *	2008-02-13	2010-05-14	Top Pharm Lab	Composition pour le traitement des affections inflammatoires des voies respiratoires a base d'une alfa-amylase et d'un anesthesique local et son procede de preparation
US8652443B2 (en) *	2008-02-14	2014-02-18	Precision Dermatology, Inc.	Foamable microemulsion compositions for topical administration
CN102065694A (zh) *	2008-04-15	2011-05-18	萨可德公司	用于局部治疗免疫相关疾病的雾化的lfa-1拮抗剂
US8555875B2 (en)	2008-12-23	2013-10-15	Map Pharmaceuticals, Inc.	Inhalation devices and related methods for administration of sedative hypnotic compounds
CN102093248B (zh) *	2010-12-22	2013-12-04	蚌埠丰原医药科技发展有限公司	一种制备盐酸丙胺卡因的方法
US20130156823A1 (en) *	2011-12-20	2013-06-20	MAP Pharmacauticals, Inc.	Excipient-free Aerosol Formulation
US10231961B1 (en)	2017-02-07	2019-03-19	Genus Lifesciences Inc.	Pharmaceutical compositions and methods of using the same
US10149843B1 (en)	2017-02-07	2018-12-11	Gneus Lifescineces Inc.	Pharmaceutical compositions and methods of using the same
US10413505B1 (en)	2017-02-07	2019-09-17	Genus Lifesciences Inc.	Pharmaceutical compositions and methods of using the same
EP3990039A1 (de) *	2019-06-25	2022-05-04	KCI Licensing, Inc.	Vorrichtung zur abgabe eines fliessfähigen gewebeverbandmaterials und verwendungsverfahren
CN112274498B (zh) *	2020-11-09	2021-09-07	北京中泰邦医药科技有限公司	一种复方利多卡因气雾剂及其制备方法

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US5380754A (en) *	1988-02-29	1995-01-10	Virotex Corporation	Topical composition enhancing healing of viral lesions
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US5118494A (en) *	1990-03-23	1992-06-02	Minnesota Mining And Manufacturing Company	Use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
US5190029A (en) *	1991-02-14	1993-03-02	Virginia Commonwealth University	Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
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US5510339A (en) *	1993-02-02	1996-04-23	Mayo Foundation For Medical Education And Research	Method for the treatment of bronchial asthma by administration of topical anesthetics
DE69420401T2 (de) *	1993-03-29	2000-05-04	Lynchris Pharmaceuticals, Ltd.	Anästhetikum in aerosolform auf der basis von lidocain
US5453445A (en) *	1994-05-02	1995-09-26	Henry; Richard A.	Lidocaine-phenylephrine aerosol preparation

1995
- 1995-05-05 US US08/435,812 patent/US5589156A/en not_active Expired - Lifetime
1996
- 1996-03-04 DK DK96902844T patent/DK0814793T3/da active
- 1996-03-04 WO PCT/CA1996/000122 patent/WO1996029066A1/en not_active Ceased
- 1996-03-04 ES ES96902844T patent/ES2203676T3/es not_active Expired - Lifetime
- 1996-03-04 AT AT96902844T patent/ATE245025T1/de active
- 1996-03-04 EP EP96902844A patent/EP0814793B1/de not_active Expired - Lifetime
- 1996-03-04 BR BR9607988-6A patent/BR9607988A/pt active IP Right Grant
- 1996-03-04 JP JP52792396A patent/JP4117707B2/ja not_active Expired - Lifetime
- 1996-03-04 PT PT96902844T patent/PT814793E/pt unknown
- 1996-03-04 AU AU47113/96A patent/AU710600B2/en not_active Expired
- 1996-03-04 CN CNB961926457A patent/CN1149080C/zh not_active Expired - Lifetime
- 1996-03-04 DE DE69629109T patent/DE69629109T2/de not_active Expired - Lifetime
2014
- 2014-03-18 LU LU92402C patent/LU92402I2/fr unknown

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Publication number	Publication date
JP4117707B2 (ja)	2008-07-16
DE69629109T2 (de)	2004-04-15
CN1149080C (zh)	2004-05-12
ES2203676T3 (es)	2004-04-16
DK0814793T3 (da)	2003-12-01
WO1996029066A1 (en)	1996-09-26
EP0814793A1 (de)	1998-01-07
EP0814793B1 (de)	2003-07-16
LU92402I2 (fr)	2014-05-19
US5589156A (en)	1996-12-31
DE69629109D1 (de)	2003-08-21
PT814793E (pt)	2003-12-31
BR9607988A (pt)	1999-11-30
AU4711396A (en)	1996-10-08
MX9707073A (es)	1998-08-30
JPH11502202A (ja)	1999-02-23
CN1179103A (zh)	1998-04-15
AU710600B2 (en)	1999-09-23

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