ATE245190T1 - Robo: eine familie polypeptiden und nukleinesäuren wirksam in nervenzellleitung - Google Patents

Robo: eine familie polypeptiden und nukleinesäuren wirksam in nervenzellleitung

Info

Publication number
ATE245190T1
ATE245190T1 AT98953776T AT98953776T ATE245190T1 AT E245190 T1 ATE245190 T1 AT E245190T1 AT 98953776 T AT98953776 T AT 98953776T AT 98953776 T AT98953776 T AT 98953776T AT E245190 T1 ATE245190 T1 AT E245190T1
Authority
AT
Austria
Prior art keywords
robo
polypeptides
nucleic acids
family
nerve cell
Prior art date
Application number
AT98953776T
Other languages
English (en)
Inventor
Corey S Goodman
Thomas Kidd
Kevin J Mitchell
Guy Tear
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of ATE245190T1 publication Critical patent/ATE245190T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT98953776T 1997-10-20 1998-10-20 Robo: eine familie polypeptiden und nukleinesäuren wirksam in nervenzellleitung ATE245190T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6292197P 1997-10-20 1997-10-20
US97117297A 1997-11-14 1997-11-14
PCT/US1998/022164 WO1999020764A1 (en) 1997-10-20 1998-10-20 Robo: a family of polypeptides and nucleic acids involved in nerve guidance

Publications (1)

Publication Number Publication Date
ATE245190T1 true ATE245190T1 (de) 2003-08-15

Family

ID=26742861

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98953776T ATE245190T1 (de) 1997-10-20 1998-10-20 Robo: eine familie polypeptiden und nukleinesäuren wirksam in nervenzellleitung

Country Status (8)

Country Link
US (2) US20050059040A1 (de)
EP (1) EP1025231B1 (de)
JP (2) JP2003517262A (de)
AT (1) ATE245190T1 (de)
AU (1) AU729496B2 (de)
CA (1) CA2304926C (de)
DE (1) DE69816467T2 (de)
WO (1) WO1999020764A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1586660A1 (de) * 1997-04-18 2005-10-19 Millennium Pharmaceuticals, Inc. Neue Moleküle der T85-verwandten Proteinfamilie und ihre Verwendung
US7034132B2 (en) 2001-06-04 2006-04-25 Anderson David W Therapeutic polypeptides, nucleic acids encoding same, and methods of use
WO2003029818A2 (en) * 2001-10-02 2003-04-10 Medical Research Council Methods and animal models for tumor formation involving dutti
WO2003029488A2 (en) * 2001-10-02 2003-04-10 Medical Research Council A method for the early detection of cancer
ES2431040T3 (es) * 2002-03-08 2013-11-22 Shanghai Institutes For Biological Sciences, Cas Detección y modulación de la angiogénesis mediada por Slit y Roundabout (Robo), y sus usos
EP2311468B1 (de) 2003-08-08 2014-01-15 Perseus Proteomics Inc. In Krebs überexprimiertes Gen
KR101300544B1 (ko) 2004-03-31 2013-09-02 히로유키 아브라타니 항ｒｏｂｏ1항체를 이용하는 암의 진단 및 치료
JP5117765B2 (ja) 2007-05-28 2013-01-16 国立大学法人 東京大学 抗ｒｏｂｏ１抗体を含むｐｅｔ用腫瘍診断剤
FR2958936A1 (fr) * 2010-04-14 2011-10-21 Sanofi Aventis Proteine de fusion robo1-fc et son utilisation dans le traitement des tumeurs
FR2969617A1 (fr) * 2010-12-23 2012-06-29 Sanofi Aventis Proteine de fusion robo1-fc et son utilisation dans le traitement des tumeurs.
JP2014507395A (ja) * 2010-12-23 2014-03-27 サノフイ 肝癌の治療における使用のためのＲｏｂｏ１−Ｆｃ融合タンパク質
SG11201403746SA (en) * 2012-01-05 2014-07-30 Boston Medical Ct Corp Slit-robo signaling for diagnosis and treatment of kidney disease
KR20200016292A (ko) 2017-06-02 2020-02-14 화이자 인코포레이티드 재조합 robo2 단백질, 조성물, 방법 및 그의 용도
US11406682B2 (en) 2017-08-24 2022-08-09 Bar-Ilan University Roundabout (Robo) receptor inhibitors and uses thereof
US20220348628A1 (en) * 2019-09-24 2022-11-03 The Regents Of The University Of California Novel receptors having a fibronectin repeat for ligand-dependent transcriptional regulation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565331A (en) * 1993-11-12 1996-10-15 The Regents Of The University Of California Nucleic acids encoding neural axon outgrowth modulators
JP2002514078A (ja) * 1997-04-18 2002-05-14 ミレニアム ファーマシューティカルズ インク． Ｆｔｈｍａ−０７０関連蛋白質ファミリーおよびｔ８５関連蛋白質ファミリーの新規分子ならびにそれらの使用

Also Published As

Publication number Publication date
JP2006174839A (ja) 2006-07-06
US20050059040A1 (en) 2005-03-17
AU1105799A (en) 1999-05-10
AU729496B2 (en) 2001-02-01
JP4636413B2 (ja) 2011-02-23
CA2304926C (en) 2005-06-21
DE69816467T2 (de) 2004-04-15
EP1025231B1 (de) 2003-07-16
WO1999020764A1 (en) 1999-04-29
EP1025231A1 (de) 2000-08-09
JP2003517262A (ja) 2003-05-27
US20100233819A1 (en) 2010-09-16
CA2304926A1 (en) 1999-04-29
DE69816467D1 (de) 2003-08-21

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