ATE247108T1 - Antifungale tetrahydrofurane - Google Patents
Antifungale tetrahydrofuraneInfo
- Publication number
- ATE247108T1 ATE247108T1 AT96921326T AT96921326T ATE247108T1 AT E247108 T1 ATE247108 T1 AT E247108T1 AT 96921326 T AT96921326 T AT 96921326T AT 96921326 T AT96921326 T AT 96921326T AT E247108 T1 ATE247108 T1 AT E247108T1
- Authority
- AT
- Austria
- Prior art keywords
- ester
- group
- tetrahydrofuranes
- antifungal
- ether
- Prior art date
Links
- -1 heterocyclic ester Chemical class 0.000 abstract 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 206010017533 Fungal infection Diseases 0.000 abstract 1
- 208000031888 Mycoses Diseases 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 239000004721 Polyphenylene oxide Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 229920000570 polyether Polymers 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30595P | 1995-06-19 | 1995-06-19 | |
| US59685296A | 1996-02-05 | 1996-02-05 | |
| PCT/US1996/009242 WO1997000255A1 (en) | 1995-06-19 | 1996-06-17 | Tetrahydrofuran antifungals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE247108T1 true ATE247108T1 (de) | 2003-08-15 |
Family
ID=26667465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96921326T ATE247108T1 (de) | 1995-06-19 | 1996-06-17 | Antifungale tetrahydrofurane |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0837859B1 (de) |
| JP (1) | JPH11507668A (de) |
| AT (1) | ATE247108T1 (de) |
| AU (1) | AU6257396A (de) |
| CA (1) | CA2224707A1 (de) |
| DE (1) | DE69629474T2 (de) |
| ES (1) | ES2203707T3 (de) |
| IL (1) | IL118668A0 (de) |
| MX (1) | MX9710270A (de) |
| WO (1) | WO1997000255A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU725302C (en) | 1997-02-11 | 2001-08-23 | Janssen Pharmaceutica N.V. | Amino acid ester containing azole antifungals |
| EP0957101A1 (de) * | 1998-05-14 | 1999-11-17 | Janssen Pharmaceutica N.V. | Wasserlösliche Azole als Breitspektrum-antifungus |
| ES2194723T3 (es) | 1999-05-04 | 2003-12-01 | Janssen Pharmaceutica Nv | Eteres antifungicos. |
| MX2011002519A (es) * | 2008-09-08 | 2011-04-21 | Wu Nian | Triazoles con caracteristicas antifúngicas. |
| US9206146B2 (en) | 2010-05-19 | 2015-12-08 | Sandoz Ag | Purification of posaconazole and of posaconazole intermediates |
| RU2580318C2 (ru) * | 2010-05-19 | 2016-04-10 | Сандоз Аг | Получение промежуточных продуктов для синтеза позаконазола |
| EP2571871B1 (de) * | 2010-05-19 | 2017-06-21 | Sandoz AG | Verfahren zur Herstellung von chiralen Triazolonen |
| US9199919B2 (en) | 2010-05-19 | 2015-12-01 | Sandoz Ag | Process for the preparation of chiral hydrazides |
| CN108329303A (zh) | 2011-06-16 | 2018-07-27 | 桑多斯股份公司 | 制备手性化合物的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL103558A0 (en) * | 1991-10-30 | 1993-03-15 | Schering Corp | Tri-substituted tetrahydrofuran antifungals |
| PL181193B1 (pl) * | 1993-12-21 | 2001-06-29 | Schering Corp | Nowe pochodne tetrahydrofuranowe o działaniu przeciwgrzybicznym, kompozycja farmaceutyczna do leczenia infekcji grzybiczych oraz sposób wytwarzania tych związków |
| NZ278882A (en) * | 1994-01-24 | 1997-06-24 | Janssen Pharmaceutica Nv | Piperazine-containing azole antifungal compounds |
-
1996
- 1996-06-17 CA CA002224707A patent/CA2224707A1/en not_active Abandoned
- 1996-06-17 ES ES96921326T patent/ES2203707T3/es not_active Expired - Lifetime
- 1996-06-17 AU AU62573/96A patent/AU6257396A/en not_active Abandoned
- 1996-06-17 WO PCT/US1996/009242 patent/WO1997000255A1/en not_active Ceased
- 1996-06-17 JP JP9503170A patent/JPH11507668A/ja active Pending
- 1996-06-17 DE DE69629474T patent/DE69629474T2/de not_active Expired - Fee Related
- 1996-06-17 EP EP96921326A patent/EP0837859B1/de not_active Expired - Lifetime
- 1996-06-17 IL IL11866896A patent/IL118668A0/xx unknown
- 1996-06-17 MX MX9710270A patent/MX9710270A/es not_active IP Right Cessation
- 1996-06-17 AT AT96921326T patent/ATE247108T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2224707A1 (en) | 1997-01-03 |
| WO1997000255A1 (en) | 1997-01-03 |
| MX9710270A (es) | 1998-08-30 |
| EP0837859A1 (de) | 1998-04-29 |
| JPH11507668A (ja) | 1999-07-06 |
| IL118668A0 (en) | 1996-10-16 |
| ES2203707T3 (es) | 2004-04-16 |
| DE69629474D1 (de) | 2003-09-18 |
| EP0837859B1 (de) | 2003-08-13 |
| DE69629474T2 (de) | 2004-06-24 |
| AU6257396A (en) | 1997-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |