ATE247169T1 - Bacteriophagen-lysine und deren anwendungen zum vernichten von und testen auf bakterien - Google Patents

Bacteriophagen-lysine und deren anwendungen zum vernichten von und testen auf bakterien

Info

Publication number
ATE247169T1
ATE247169T1 AT92303533T AT92303533T ATE247169T1 AT E247169 T1 ATE247169 T1 AT E247169T1 AT 92303533 T AT92303533 T AT 92303533T AT 92303533 T AT92303533 T AT 92303533T AT E247169 T1 ATE247169 T1 AT E247169T1
Authority
AT
Austria
Prior art keywords
bacteria
bacteriophagen
lysines
destroying
testing
Prior art date
Application number
AT92303533T
Other languages
English (en)
Inventor
Michael John Gasson
Original Assignee
Inst Of Food Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Of Food Res filed Critical Inst Of Food Res
Application granted granted Critical
Publication of ATE247169T1 publication Critical patent/ATE247169T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729—Organic compounds; Microorganisms; Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729—Organic compounds; Microorganisms; Enzymes
    • A23B2/783—Microorganisms; Enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/33—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Clostridium (G)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT92303533T 1991-04-20 1992-04-21 Bacteriophagen-lysine und deren anwendungen zum vernichten von und testen auf bakterien ATE247169T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9108498A GB2255561B (en) 1991-04-20 1991-04-20 Lysins from bacteriophages

Publications (1)

Publication Number Publication Date
ATE247169T1 true ATE247169T1 (de) 2003-08-15

Family

ID=10693655

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92303533T ATE247169T1 (de) 1991-04-20 1992-04-21 Bacteriophagen-lysine und deren anwendungen zum vernichten von und testen auf bakterien

Country Status (7)

Country Link
US (2) US5763251A (de)
EP (2) EP1300082A3 (de)
AT (1) ATE247169T1 (de)
AU (1) AU650737B2 (de)
CA (1) CA2066387C (de)
DE (1) DE69233152T2 (de)
GB (1) GB2255561B (de)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955258A (en) * 1994-05-12 1999-09-21 Quest International B.V. Process for the lysis of a culture of lactic acid bacteria by means of a lysin, and uses of the resulting lysed culture
EP0759999A1 (de) * 1994-05-12 1997-03-05 Quest International B.V. Verfahren zur hemmung von milchsäurebakterienwachstum, und lyse von bakterienzellen und anwendung dieser lysierten kultur
EP0781349B1 (de) * 1994-09-09 2003-01-15 Biotec Laboratories Limited Aufschluss von bakterienzellen durch phagenlysine
US6423299B1 (en) 1997-10-31 2002-07-23 Vincent Fischetti Composition for treatment of a bacterial infection of an upper respiratory tract
US6406692B1 (en) 1997-10-31 2002-06-18 New Horizons Diagnostics Corp Composition for treatment of an ocular bacterial infection
US7232576B2 (en) 1997-10-31 2007-06-19 New Horizons Diagnostics Corp Throat lozenge for the treatment of Streptococcus Group A
US6752988B1 (en) 2000-04-28 2004-06-22 New Horizons Diagnostic Corp Method of treating upper resiratory illnesses
US6277399B1 (en) 1997-10-31 2001-08-21 New Horizon Diagnostics Corporation Composition incorporating bacterial phage associated lysing enzymes for treating dermatological infections
US6399097B1 (en) 1997-10-31 2002-06-04 New Horizons Diagnostics Corporation Composition for treatment of a bacterial infection of the digestive tract
US20030129147A1 (en) * 1997-10-31 2003-07-10 Vincent Fischetti Use of bacterial phage associated lysing proteins for treating bacterial dental caries
US20020136712A1 (en) * 1997-10-31 2002-09-26 Fischetti Vincent Bacterial phage associated lysing enzymes for the prophylactic and therapeutic treatment of colonization and infections caused by streptococcus pneumoniae
US20030129146A1 (en) * 1997-10-31 2003-07-10 Vincent Fischetti The use of bacterial phage associated lysing proteins for treating bacterial dental caries
US6399098B1 (en) 1997-10-31 2002-06-04 New Horizons Diagnostics Corp Composition for treating dental caries caused by streptococcus mutans
US6432444B1 (en) 1997-10-31 2002-08-13 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymes for treating dermatological infections
US6056954A (en) 1997-10-31 2000-05-02 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses
US6428784B1 (en) * 1997-10-31 2002-08-06 New Horizons Diagnostics Corp Vaginal suppository for treating group B Streptococcus infection
US20030082110A1 (en) * 1997-10-31 2003-05-01 Vincent Fischetti Use of bacterial phage associated lysing proteins for treating bacterial dental caries
US6143551A (en) * 1997-12-29 2000-11-07 Schering Aktiengesellschaft Delivery of polypeptide-encoding plasmid DNA into the cytosol of macrophages by attenuated listeria suicide bacteria
US6391626B1 (en) 1999-08-23 2002-05-21 3M Innovative Properties Company Culture medium and device using ballasted pH indicators for detection and enumeration of microorganisms
US20020127215A1 (en) * 1999-09-14 2002-09-12 Lawrence Loomis Parenteral use of bacterial phage associated lysing enzymes for the therapeutic treatment of bacterial infections
US7063837B2 (en) * 1999-09-14 2006-06-20 New Horizons Diagnostics Corp Syrup composition containing phage associated lytic enzymes
CN1230206C (zh) * 2000-01-11 2005-12-07 内立蒂克斯股份有限公司 作为生产生物复合材料的生物可降解基质的聚合物混合物
US6436661B1 (en) * 2000-04-13 2002-08-20 3M Innovative Properties Company Bacteria and bacteriophage detection using immobilized enzyme substrates
AU2001259205A1 (en) * 2000-04-28 2001-11-12 New Horizons Diagnostic Corporation The use of bacterial phage associated lysing enzymes for treating various illnesses
US6395504B1 (en) 2000-09-01 2002-05-28 New Horizons Diagnostics Corp. Use of phage associated lytic enzymes for the rapid detection of bacterial contaminants
CA2427928A1 (en) * 2000-11-02 2002-12-27 New Horizons Diagnostics Corporation The use of bacterial phage associated lytic enzymes to prevent food poisoning
AU2002322275A1 (en) * 2001-06-20 2003-01-08 Mayo Foundation For Medical Education And Research Adenosyl-cobalamin fortified compositions
US20040213765A1 (en) * 2001-07-13 2004-10-28 Vincent Fischetti Use of bacterial phage associated lytic enzymes to prevent food poisoning
WO2003008564A2 (en) 2001-07-18 2003-01-30 Instytut Immunologii I Terapii Doswiadczalnej Pan Methods of polyvalent bacteriophage preparation for the treatment of bacterial infections
ES2559668T3 (es) * 2001-09-27 2016-02-15 Gangagen, Inc. Bacteriófagos deficientes en lisina, que tienen inmunogenicidad reducida
US20030148268A1 (en) * 2001-12-06 2003-08-07 The Rockefeller University Novel method to identify targets for antibiotic development
GB0202556D0 (en) * 2002-02-04 2002-03-20 Danisco Novel Protein
ATE469240T1 (de) 2002-04-12 2010-06-15 Colorado School Of Mines Verfahren zum nachweis geringer konzentrationen eines zielbakteriums unter verwendung von phagen zur infizierung von zielbakterienzellen
US8216780B2 (en) 2002-04-12 2012-07-10 Microphage (Tm) Incorporated Method for enhanced sensitivity in bacteriophage-based diagnostic assays
WO2003103578A2 (en) * 2002-06-05 2003-12-18 Iowa State University Research Foundation, Inc. Bacteriophage and enzymes lytic to salmonellae
US20040081646A1 (en) * 2002-08-29 2004-04-29 Engler Jeffrey A. Group B Streptococcal phage lysin
US20050129711A1 (en) * 2002-11-14 2005-06-16 Janakiraman Ramachandran Incapacitated whole-cell immunogenic bacterial compositions produced by recombinant expression
WO2008157384A2 (en) 2007-06-15 2008-12-24 Microphage Incorporated Method of detection of microorganisms with enhanced bacteriophage amplification
WO2006105504A1 (en) 2005-03-31 2006-10-05 Microphage Incorporated Apparatus and method for detecting microorganisms using flagged bacteriophage
EP2102346A2 (de) * 2007-01-09 2009-09-23 Guild Associates, Inc. Hefe-biokatalysatoren zum abbau von mitteln zur biologischen kriegsführung
CN101952424A (zh) 2007-08-22 2011-01-19 海格罗斯投资有限责任公司 用于人类和动物葡萄球菌感染的新蛋白
KR100974185B1 (ko) * 2007-08-27 2010-08-05 주식회사 인트론바이오테크놀로지 박테리오파지 유래 용균단백질 작용에 의해 제조된세균파쇄물 및 이를 포함하는 동물질병 예방용 백신 조성물
EP2195427A2 (de) 2007-10-01 2010-06-16 Guild Associates, Inc. Differentiell fluoreszierende hefebiosensoren zur erkennung und zum biologischen abbau chemischer mittel
US20090104157A1 (en) * 2007-10-05 2009-04-23 E. I. Du Pont De Nemours And Company Utilization of bacteriophage to control bacterial contamination in fermentation processes
CN101220350B (zh) * 2007-11-16 2010-05-19 珠海市晋平科技有限公司 一种分离的李斯特单核增生菌噬菌体及其应用
EP2225263A1 (de) * 2007-11-26 2010-09-08 Plant Bioscience Limited Neue polypeptide mit endolysinaktivität und anwendungen davon
US8697434B2 (en) 2008-01-11 2014-04-15 Colorado School Of Mines Detection of phage amplification by SERS nanoparticles
US9441204B2 (en) 2008-04-03 2016-09-13 Colorado School Of Mines Compositions and methods for detecting Yersinia pestis bacteria
EP2143729A1 (de) * 2008-07-07 2010-01-13 Hyglos Invest GmbH Neues enzymatisches Aktivenzym gegen Clostridium
GB0815484D0 (en) * 2008-08-26 2008-10-01 Univ Leuven Kath Antibacterial agents
PL215522B1 (pl) 2008-09-29 2013-12-31 Inst Immunologii I Terapii Doswiadczalnej Pan Nowe szczepy bakteriofagów do leczenia zakazen bakteryjnych, zwlaszcza szczepami bakterii lekoopornych rodzaju Enterococcus
GB0908949D0 (en) 2009-05-26 2009-07-01 Plant Bioscience Ltd Novel polypeptides having endolysin activity and uses thereof
US20120195872A1 (en) 2009-06-26 2012-08-02 Lysando Ag Antimicrobial agents
PL2445515T3 (pl) 2009-06-26 2016-10-31 Środki przeciwdrobnoustrojowe
US8778669B2 (en) 2009-07-22 2014-07-15 Corning Incorporated Multilayer tissue culture vessel
JP5847081B2 (ja) 2009-08-24 2016-01-20 カトリック ユニバーシテイト ルーベン ケイ．ユー． ルーベン アール アンド ディー エンドリシンＯＢＰｇｐＬＹＳ
EP2338916A1 (de) 2009-12-23 2011-06-29 Hyglos Invest GmbH Chimäre Polypeptide und ihre Verwendung zur bakteriellen Dekolonisation
EP2397548A1 (de) 2010-06-18 2011-12-21 Hyglos Invest GmbH Verfahren zur Herstellung und zum Screening von lytischen chimärischen Polypeptiden
PL212258B1 (pl) 2010-06-20 2012-09-28 Inst Immunologii I Terapii Doswiadczalnej Pan Nowe szczepy bakteriofagów do leczenia zakazen bakteryjnych, zwlaszcza szczepami bakterii lekoopornych rodzaju Stenotrophomonas
US8962297B2 (en) * 2010-09-01 2015-02-24 The United States Of America, As Represented By The Secretary Of Agriculture Bacteriophage lytic enzymes as alternative antimicrobials
AU2014302735B2 (en) 2013-06-27 2016-12-15 Starbucks Corporation D/B/A Starbucks Coffee Company Biopreservation methods for beverages and other foods
EP3372091A1 (de) * 2017-03-07 2018-09-12 Nomad Bioscience GmbH Verfahren zur verringerung der verschmutzung eines objekts mit clostridium
CA3143745A1 (en) * 2019-07-18 2021-01-21 Kilian VOGELE Host-independent expression of bacteriophages
EP4721573A1 (de) 2024-10-03 2026-04-08 Consejo Superior De Investigaciones Científicas - CSIC Kombination aus bakteriophagen-abgeleiteten endolysinen und glucoseoxidase und verwendungen davon

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3094466A (en) * 1959-07-15 1963-06-18 Warner Lambert Pharmaceutical Preparation for typing of staphylococci and process therefor
US3002892A (en) * 1960-01-20 1961-10-03 Elmo S Dooley Process for preparing bacteriophage-impregnated paper discs for rapid identificationof bacterial strains
US3793151A (en) * 1972-07-10 1974-02-19 J Denney Method of screening for anticapsular substances
US4618576A (en) * 1984-02-27 1986-10-21 Becton Dickinson And Company Diagnostic test for Streptococcus A
IT1197924B (it) * 1986-10-28 1988-12-21 Prodotti Antibiotici Spa Procedimento per la preparazione di alimenti di origine animale
GB8710795D0 (en) * 1987-05-07 1987-06-10 Microbial Dev Ltd Antimicrobial preparations
US4859597A (en) * 1987-07-27 1989-08-22 Igene Biotechnology, Inc. Production of phage and phage-associated lysin
GB8816693D0 (en) * 1988-07-13 1988-08-17 Agricultural & Food Res Viral enzyme & gene

Also Published As

Publication number Publication date
CA2066387A1 (en) 1992-10-21
AU1502392A (en) 1992-10-22
GB2255561A (en) 1992-11-11
GB9108498D0 (en) 1991-06-05
EP0510907A2 (de) 1992-10-28
EP1300082A2 (de) 2003-04-09
AU650737B2 (en) 1994-06-30
US5763251A (en) 1998-06-09
US6083684A (en) 2000-07-04
CA2066387C (en) 2003-07-01
DE69233152D1 (de) 2003-09-18
EP0510907A3 (en) 1993-03-03
EP0510907B1 (de) 2003-08-13
DE69233152T2 (de) 2004-05-27
GB2255561B (en) 1995-06-21
EP1300082A3 (de) 2003-11-19

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