ATE247491T1 - Verfahren zur photoakustische bilderzeugung - Google Patents

Verfahren zur photoakustische bilderzeugung

Info

Publication number
ATE247491T1
ATE247491T1 AT98930870T AT98930870T ATE247491T1 AT E247491 T1 ATE247491 T1 AT E247491T1 AT 98930870 T AT98930870 T AT 98930870T AT 98930870 T AT98930870 T AT 98930870T AT E247491 T1 ATE247491 T1 AT E247491T1
Authority
AT
Austria
Prior art keywords
radiation
image generation
photoacoustic image
generating
contrast agent
Prior art date
Application number
AT98930870T
Other languages
English (en)
Inventor
Paul Mark Henrichs
Morten Eriksen
Pal Rongved
Wolfgang Hans Heinrich Gunther
Robert Allen Snow
Kenneth Robert Hollister
Gregory Lynn Mcintire
Original Assignee
Amersham Health As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Health As filed Critical Amersham Health As
Application granted granted Critical
Publication of ATE247491T1 publication Critical patent/ATE247491T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0002General or multifunctional contrast agents, e.g. chelated agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032Methine dyes, e.g. cyanine dyes
    • A61K49/0034Indocyanine green, i.e. ICG, cardiogreen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0063Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0076Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion
    • A61K49/0078Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion microemulsion, nanoemulsion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0063Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0076Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion
    • A61K49/0084Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion liposome, i.e. bilayered vesicular structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0063Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0089Particulate, powder, adsorbate, bead, sphere
    • A61K49/0091Microparticle, microcapsule, microbubble, microsphere, microbead, i.e. having a size or diameter higher or equal to 1 micrometer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0404X-ray contrast preparations containing barium sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461Dispersions, colloids, emulsions or suspensions
    • A61K49/0466Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/50Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A61B6/508Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for non-human patients
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/932Specified use of nanostructure for electronic or optoelectronic application
    • Y10S977/949Radiation emitter using nanostructure

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Nanotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Semiconductor Lasers (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Holo Graphy (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
AT98930870T 1997-06-16 1998-06-16 Verfahren zur photoakustische bilderzeugung ATE247491T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9712524.9A GB9712524D0 (en) 1997-06-16 1997-06-16 Method
PCT/GB1998/001751 WO1998057667A1 (en) 1997-06-16 1998-06-16 Methods of photoacoustic imaging

Publications (1)

Publication Number Publication Date
ATE247491T1 true ATE247491T1 (de) 2003-09-15

Family

ID=10814249

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98930870T ATE247491T1 (de) 1997-06-16 1998-06-16 Verfahren zur photoakustische bilderzeugung

Country Status (9)

Country Link
US (1) US6662040B1 (de)
EP (1) EP0996469B1 (de)
JP (1) JP4436461B2 (de)
AT (1) ATE247491T1 (de)
AU (1) AU8115898A (de)
DE (1) DE69817360T2 (de)
ES (1) ES2206951T3 (de)
GB (1) GB9712524D0 (de)
WO (1) WO1998057667A1 (de)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6630570B1 (en) 1999-04-09 2003-10-07 Insitut für Diagnostikforschung GmbH Short-chain peptide-dye conjugates as contrast media for optical diagnosis
DE19917713A1 (de) * 1999-04-09 2000-10-19 Diagnostikforschung Inst Kurzkettige Peptid-Farbstoffkonjugate als Konstrastmittel für die optische Diagnostik
US7175953B2 (en) 1999-04-09 2007-02-13 Institute Fuer Diagnostik Forschung Short-warp peptide-dye conjugate as contrast agent for optical diagnostic
JP2001299676A (ja) * 2000-04-25 2001-10-30 Fuji Photo Film Co Ltd センチネルリンパ節検出方法および検出システム
IL138073A0 (en) 2000-08-24 2001-10-31 Glucon Inc Photoacoustic assay and imaging system
ES2431520T3 (es) 2003-01-25 2013-11-26 Seno Medical Instruments, Inc. Procedimiento de formación de imágenes optoacústicas de contraste elevado utilizando nanopartículas no esféricas
US7387021B2 (en) * 2005-05-24 2008-06-17 Baker Hughes Incorporated Method and apparatus for reservoir characterization using photoacoustic spectroscopy
EA015095B1 (ru) * 2005-05-24 2011-06-30 Бейкер Хьюз Инкорпорейтед Способ и устройство определения характеристик коллектора с использованием фотоакустической спектроскопии
EP1889124A4 (de) 2005-05-26 2009-06-03 Araz Yacoubian Breitband-darsteller
US20070015992A1 (en) * 2005-06-30 2007-01-18 General Electric Company System and method for optoacoustic imaging
US20090054763A1 (en) * 2006-01-19 2009-02-26 The Regents Of The University Of Michigan System and method for spectroscopic photoacoustic tomography
CA2671101C (en) * 2006-01-20 2016-06-14 Seno Medical Instruments, Inc. Quantitative optoacoustic tomography with enhanced contrast
US20080123083A1 (en) * 2006-11-29 2008-05-29 The Regents Of The University Of Michigan System and Method for Photoacoustic Guided Diffuse Optical Imaging
US20080173093A1 (en) * 2007-01-18 2008-07-24 The Regents Of The University Of Michigan System and method for photoacoustic tomography of joints
WO2008103982A2 (en) * 2007-02-23 2008-08-28 The Regents Of The University Of Michigan System and method for monitoring photodynamic therapy
US20080228073A1 (en) * 2007-03-12 2008-09-18 Silverman Ronald H System and method for optoacoustic imaging of peripheral tissues
US20080241065A1 (en) * 2007-03-27 2008-10-02 Benaron David A Systems and methods for the detection and analysis of in vivo circulating cells, entities, and nanobots
US20100196278A1 (en) * 2007-11-16 2010-08-05 Canon Kabushiki Kaisha Photoacoustic imaging agent
WO2009078970A1 (en) * 2007-12-14 2009-06-25 Biotium, Inc. Fluorescent compounds
JP5284129B2 (ja) * 2008-02-06 2013-09-11 キヤノン株式会社 イメージング装置、及び解析方法
EP2110076A1 (de) 2008-02-19 2009-10-21 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Verfahren und Vorrichtung zur Nahfeld-Doppelwellen-Modalitätsbildgebung
CA2731409C (en) 2008-07-25 2016-01-05 Daniel Razansky Quantitative multi-spectral opto-acoustic tomography (msot) of tissue biomarkers
US8426933B2 (en) * 2008-08-08 2013-04-23 Araz Yacoubian Broad spectral band sensor
JP5241465B2 (ja) * 2008-12-11 2013-07-17 キヤノン株式会社 光音響イメージング装置および光音響イメージング方法
CN102438591A (zh) * 2009-03-19 2012-05-02 马维尔生物科学公司 用于增强成像对比度的组合物和方法
JP5566456B2 (ja) 2009-06-29 2014-08-06 ヘルムホルツ・ツェントルム・ミュンヒェン・ドイチェス・フォルシュンクスツェントルム・フューア・ゲズントハイト・ウント・ウムベルト(ゲーエムベーハー) 被写体を熱音響撮像するための撮像装置及び撮像方法、コンピュータプログラム並びにコンピュータで読み取り可能な記憶媒体を備える装置
US20110016962A1 (en) * 2009-07-21 2011-01-27 Baker Hughes Incorporated Detector for Characterizing a Fluid
US10292593B2 (en) 2009-07-27 2019-05-21 Helmholtz Zentrum München Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) Imaging device and method for optoacoustic imaging of small animals
US8658434B2 (en) * 2009-10-28 2014-02-25 Biotium, Inc. Fluorescent pyrene compounds
US9427186B2 (en) * 2009-12-04 2016-08-30 Endomagnetics Ltd. Magnetic probe apparatus
US10634741B2 (en) 2009-12-04 2020-04-28 Endomagnetics Ltd. Magnetic probe apparatus
US9610367B2 (en) * 2010-08-24 2017-04-04 Canon Kabushiki Kaisha Particle and contrast agent having the particle
BR112013015814A2 (pt) * 2010-12-22 2018-05-15 Koninl Philips Electronics Nv agente de contraste de formação de imagem, segundo agente de contraste fotoacústico, método, método para formar, como uma mistura, um segundo agente de contraste fotoacústico, dispositivo configurado para localizar uma ou mais localizações de uma fonte de energia acústica, dispositivo configurado para utilizar atrasos de tempo e direções do ultrassom recebido de uma pluralidade de bolhas para localizar uma fonte de energia acústica, produto de software de computador para formação de imagem, sinal e método para gerar o sinal
WO2012136813A2 (en) * 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
EP2720615B1 (de) * 2011-06-20 2016-04-06 Koninklijke Philips N.V. Wirkstoffbildgebung
US8843190B2 (en) * 2011-07-21 2014-09-23 The Board Of Trustees Of The Leland Stanford Junior University Medical screening and diagnostics based on air-coupled photoacoustics
US9517278B2 (en) 2012-07-20 2016-12-13 Canon Kabushiki Kaisha Compound and photoacoustic imaging contrast medium containing the compound
CN104470546B (zh) 2012-07-20 2018-02-27 佳能株式会社 化合物和含有所述化合物的光声成像造影剂
EP2742854B1 (de) 2012-12-11 2021-03-10 iThera Medical GmbH Tragbare Vorrichtung und Verfahren für tomographische optoakustische Bildgebung eines Objekts
EP2754388B1 (de) 2013-01-15 2020-09-09 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH System und Verfahren zur optoakustischen Abbildung eines Objekts mit verbesserter Qualität und hoher Rate
ES2803506T3 (es) 2013-03-11 2021-01-27 Endomagnetics Ltd Soluciones hipoosmóticas para la detección de ganglios linfáticos
US9234877B2 (en) 2013-03-13 2016-01-12 Endomagnetics Ltd. Magnetic detector
US9239314B2 (en) 2013-03-13 2016-01-19 Endomagnetics Ltd. Magnetic detector
EP3003396B1 (de) * 2013-05-24 2020-04-08 University Health Network Multimodale optische ct-mittel
WO2015077088A1 (en) 2013-11-22 2015-05-28 Massachusetts Institute Of Technology System and method for non-contact ultrasound
US10398315B2 (en) 2013-12-06 2019-09-03 Agency For Science, Technology And Research Method of imaging living tissue
CA2954064C (en) * 2014-07-02 2018-10-30 The Research Foundation For The State University Of New York Surfactant-stripped micelle compositions with high cargo to surfactant ratio
US10398788B2 (en) 2014-10-24 2019-09-03 Canon Kabushiki Kaisha Polymer and contrast agent for photoacoustic imaging including the polymer
KR101638588B1 (ko) * 2015-04-23 2016-07-12 포항공과대학교 산학협력단 소화기관의 비침습적 이미징 장치
MX390935B (es) 2015-06-04 2025-03-21 Endomagnetics Ltd Materiales marcadores y formas para la localización de marcadores magnéticos (mml).
US10602931B2 (en) 2016-03-14 2020-03-31 Massachusetts Institute Of Technology System and method for non-contact ultrasound with enhanced safety
ITUA20164756A1 (it) * 2016-06-29 2017-12-29 Bio On Spa Nanoparticelle polimeriche biocompatibili contenenti nanostrutture metalliche funzionali, processo di preparazione e relativo uso in campo diagnostico e/o terapeutico.
US10780185B2 (en) 2017-01-30 2020-09-22 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Multifunctional nanoparticle bioconjugates for photoacoustic-based recording of cellular membrane potential
DE102017201543A1 (de) * 2017-01-31 2018-08-02 Siemens Healthcare Gmbh Quantifizierung von Blutverlust auf Basis einer Computertomographie mit einem direkt konvertierenden Detektor
CN106990048B (zh) * 2017-05-18 2020-04-14 厦门大学 一种基于光声成像技术的活细菌检测方法
US11082127B1 (en) * 2019-03-07 2021-08-03 Massachusetts Institute Of Technology Methods and apparatus for acoustic laser communications
CN109985252A (zh) * 2019-05-10 2019-07-09 南京鼓楼医院 一种新型双模态小分子造影剂及其制备方法与应用
EP3932295A1 (de) * 2020-06-30 2022-01-05 Universität Zürich Optoakustisches tomographieverfahren eines lebenden organismus, optoakustische 2d- oder 3d-bilder, 2d- oder 3d-blutfluss- und lichtfluenzbilder und photoabsorbierendes mittel zur verwendung in einem optoakustischen verfahren
JP7842776B2 (ja) * 2021-03-17 2026-04-08 プルーヴファーム・ライフ・ソリューションズ インドシアニングリーンの安定な処方物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4267732A (en) * 1978-11-29 1981-05-19 Stanford University Board Of Trustees Acoustic microscope and method
US4442843A (en) * 1980-11-17 1984-04-17 Schering, Ag Microbubble precursors and methods for their production and use
US4385634A (en) * 1981-04-24 1983-05-31 University Of Arizona Foundation Radiation-induced thermoacoustic imaging
SE8804074D0 (sv) * 1988-11-10 1988-11-10 Pharmacia Ab Sensorenhet och dess anvaendning i biosensorsystem
JP3260884B2 (ja) * 1993-02-05 2002-02-25 キヤノン株式会社 標識複合体、それを用いる分析法、生体関連物質の検出および定量の方法
DE4445065A1 (de) * 1994-12-07 1996-06-13 Diagnostikforschung Inst Verfahren zur In-vivo-Diagnostik mittels NIR-Strahlung
US5840023A (en) * 1996-01-31 1998-11-24 Oraevsky; Alexander A. Optoacoustic imaging for medical diagnosis
US6309352B1 (en) * 1996-01-31 2001-10-30 Board Of Regents, The University Of Texas System Real time optoacoustic monitoring of changes in tissue properties
US6022309A (en) * 1996-04-24 2000-02-08 The Regents Of The University Of California Opto-acoustic thrombolysis
US5916538A (en) * 1996-08-27 1999-06-29 Tokyo Gas Company Limited Diagnostic agent for diabetes
US6123923A (en) * 1997-12-18 2000-09-26 Imarx Pharmaceutical Corp. Optoacoustic contrast agents and methods for their use

Also Published As

Publication number Publication date
JP4436461B2 (ja) 2010-03-24
GB9712524D0 (en) 1997-08-20
EP0996469A1 (de) 2000-05-03
JP2002508760A (ja) 2002-03-19
EP0996469B1 (de) 2003-08-20
DE69817360T2 (de) 2004-06-09
ES2206951T3 (es) 2004-05-16
DE69817360D1 (de) 2003-09-25
US6662040B1 (en) 2003-12-09
WO1998057667A1 (en) 1998-12-23
AU8115898A (en) 1999-01-04

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