ATE249237T1 - Quantifizierung einer individuellen proteinkinaseaktivität - Google Patents

Quantifizierung einer individuellen proteinkinaseaktivität

Info

Publication number
ATE249237T1
ATE249237T1 AT95913593T AT95913593T ATE249237T1 AT E249237 T1 ATE249237 T1 AT E249237T1 AT 95913593 T AT95913593 T AT 95913593T AT 95913593 T AT95913593 T AT 95913593T AT E249237 T1 ATE249237 T1 AT E249237T1
Authority
AT
Austria
Prior art keywords
protein kinase
peptide
quantification
kinase activity
binding compound
Prior art date
Application number
AT95913593T
Other languages
English (en)
Inventor
Said A Goueli
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Promega Corp filed Critical Promega Corp
Application granted granted Critical
Publication of ATE249237T1 publication Critical patent/ATE249237T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT95913593T 1994-03-04 1995-03-06 Quantifizierung einer individuellen proteinkinaseaktivität ATE249237T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/208,573 US6348310B1 (en) 1994-03-04 1994-03-04 Quantitation of individual protein kinase activity
PCT/US1995/002856 WO1995023612A1 (en) 1994-03-04 1995-03-06 Quantitation of individual protein kinase activity

Publications (1)

Publication Number Publication Date
ATE249237T1 true ATE249237T1 (de) 2003-09-15

Family

ID=22775101

Family Applications (2)

Application Number Title Priority Date Filing Date
AT95913593T ATE249237T1 (de) 1994-03-04 1995-03-06 Quantifizierung einer individuellen proteinkinaseaktivität
AT03003524T ATE333514T1 (de) 1994-03-04 1995-03-06 Quantifizierung einer individuellen proteinkinaseaktivität

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT03003524T ATE333514T1 (de) 1994-03-04 1995-03-06 Quantifizierung einer individuellen proteinkinaseaktivität

Country Status (8)

Country Link
US (3) US6348310B1 (de)
EP (2) EP1340816B1 (de)
JP (1) JPH10511260A (de)
AT (2) ATE249237T1 (de)
AU (1) AU2097595A (de)
DE (2) DE69531734T2 (de)
ES (2) ES2268178T3 (de)
WO (1) WO1995023612A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6348310B1 (en) * 1994-03-04 2002-02-19 Promega Corporation Quantitation of individual protein kinase activity
WO1997039143A2 (en) * 1996-04-17 1997-10-23 Abbott Laboratories Methods for the identification of novel antifungal agents
US6335176B1 (en) * 1998-10-16 2002-01-01 Pharmacopeia, Inc. Incorporation of phosphorylation sites
US6406869B1 (en) * 1999-10-22 2002-06-18 Pharmacopeia, Inc. Fluorescent capture assay for kinase activity employing anti-phosphotyrosine antibodies as capture and detection agents
EP1290213A2 (de) * 2000-05-31 2003-03-12 Promega Corporation Phosphatase und kinase assays
US20030162230A1 (en) 2000-09-27 2003-08-28 Reagan Kevin J. Method for quantifying phosphokinase activity on proteins
US7067269B2 (en) * 2001-11-26 2006-06-27 Echelon Biosciences, Inc. Assaying apparatus, kit, and method for lipids and associated enzymes
US7037670B2 (en) * 2002-04-19 2006-05-02 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Peptide substrates for assay of extracellular signal-regulated protein kinase 1 and 2 activity
US7195884B2 (en) * 2002-07-19 2007-03-27 Promega Corp. Methods and kits for transferases
FR2846657B1 (fr) * 2002-11-05 2004-12-24 Servier Lab Nouveaux composes pyridopyrimidinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US20060211063A1 (en) * 2003-03-12 2006-09-21 Assay Designs Inc. Phosphokinase assay
US7619059B2 (en) * 2003-07-29 2009-11-17 Life Technologies Corporation Bimolecular optical probes
US7727752B2 (en) * 2003-07-29 2010-06-01 Life Technologies Corporation Kinase and phosphatase assays
CA2445420A1 (en) * 2003-07-29 2005-01-29 Invitrogen Corporation Kinase and phosphatase assays
US20050272100A1 (en) * 2004-06-02 2005-12-08 Arthur Karlin Separation and quantification of biotinylated macromolecules
JP2007097448A (ja) * 2005-09-30 2007-04-19 Sysmex Corp 組織の性質判定用試薬キット
EP1946106A4 (de) * 2005-10-13 2009-04-08 Activesite Pharmaceuticals Verfahren zur identifizierung von inhibitoren von enzymaktivität
KR101018003B1 (ko) * 2008-06-24 2011-03-02 한국원자력연구원 인산화 반응 측정용 바이오칩 및 이를 이용한 인산화 반응측정 방법
WO2010144150A2 (en) 2009-06-12 2010-12-16 Pacific Biosciences Of California, Inc. Real-time analytical methods and systems
US9075055B2 (en) 2013-03-15 2015-07-07 Hycor Biomedical, Inc. Device and associated methods for performing luminescence and fluorescence measurements of a sample
CN103472052B (zh) * 2013-07-02 2015-08-26 南昌大学 一种多功能纳米探针GOx/Au NPs/DNA的制备方法及其激酶检测应用
JP6584322B2 (ja) * 2013-12-27 2019-10-02 国立大学法人 東京医科歯科大学 アルツハイマー病及び前頭側頭葉変性症の診断方法、診断薬、治療薬、及びこれら薬剤のスクリーニング方法
KR101430209B1 (ko) * 2014-03-06 2014-08-14 강원대학교산학협력단 단백질 키나아제 활성 측정 방법 및 이를 위한 키트
KR101683544B1 (ko) * 2014-12-19 2016-12-08 한양대학교 산학협력단 탈인산화 또는 인산화 효소 활성 검출용 조성물 및 검출 방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4594319A (en) 1984-03-19 1986-06-10 The University Of Tennessee Research Corp. Protein kinase enzyme AUT-PK 500 and a radioimmunoassay for detection of neoplasia
US4923802A (en) 1985-06-13 1990-05-08 Immunex Corporation Peptide substrates for the detection, characterization and purification of protein kinase C
ATE79635T1 (de) 1986-04-01 1992-09-15 Wako Pure Chem Ind Ltd Peptid-derivate und methode zur messung der wirksamkeit von physiologisch aktiven verbindungen, die dieselben als substraten benuetzen.
US4937232A (en) 1986-09-15 1990-06-26 Duke University Inhibition of protein kinase C by long-chain bases
US4816450A (en) 1986-09-15 1989-03-28 Duke University Inhibition of protein kinase C by long-chain bases
US5141852A (en) 1988-12-12 1992-08-25 The United States Of America As Represented By The Department Of Health And Human Services Assay of protein kinases with peptide substrates
US5235039A (en) * 1991-06-10 1993-08-10 Eli Lilly And Company Substrates for hiv protease
US5514778A (en) * 1993-07-01 1996-05-07 Eli Lilly And Company Anti-picornaviral agents
US6348310B1 (en) * 1994-03-04 2002-02-19 Promega Corporation Quantitation of individual protein kinase activity

Also Published As

Publication number Publication date
US20020106701A1 (en) 2002-08-08
EP0760678A4 (de) 1999-02-24
ATE333514T1 (de) 2006-08-15
US6753157B2 (en) 2004-06-22
DE69531734T2 (de) 2004-10-14
DE69535119T2 (de) 2007-02-08
EP1340816A2 (de) 2003-09-03
ES2268178T3 (es) 2007-03-16
EP0760678B9 (de) 2004-05-19
EP0760678A1 (de) 1997-03-12
US6066462A (en) 2000-05-23
DE69531734D1 (de) 2003-10-16
JPH10511260A (ja) 1998-11-04
EP1340816B1 (de) 2006-07-19
EP0760678B1 (de) 2003-09-10
AU2097595A (en) 1995-09-18
WO1995023612A1 (en) 1995-09-08
EP1340816A3 (de) 2003-10-15
ES2204946T3 (es) 2004-05-01
DE69535119D1 (de) 2006-08-31
US6348310B1 (en) 2002-02-19

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