ATE24997T1 - Hyperueretische mittel. - Google Patents
Hyperueretische mittel.Info
- Publication number
- ATE24997T1 ATE24997T1 AT82111893T AT82111893T ATE24997T1 AT E24997 T1 ATE24997 T1 AT E24997T1 AT 82111893 T AT82111893 T AT 82111893T AT 82111893 T AT82111893 T AT 82111893T AT E24997 T1 ATE24997 T1 AT E24997T1
- Authority
- AT
- Austria
- Prior art keywords
- agents
- amino
- hyperuetic
- treating hypertension
- urea
- Prior art date
Links
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 4
- 206010020772 Hypertension Diseases 0.000 abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 2
- 239000004202 carbamide Substances 0.000 abstract 2
- 208000037157 Azotemia Diseases 0.000 abstract 1
- JZUFKLXOESDKRF-UHFFFAOYSA-N Chlorothiazide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC2=C1NCNS2(=O)=O JZUFKLXOESDKRF-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 208000002296 eclampsia Diseases 0.000 abstract 1
- 230000029142 excretion Effects 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 229960002003 hydrochlorothiazide Drugs 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 208000009852 uremia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33673682A | 1982-01-04 | 1982-01-04 | |
| US06/336,735 US4594349A (en) | 1982-01-04 | 1982-01-04 | Hyperuretic agents |
| EP82111893A EP0083779B1 (de) | 1982-01-04 | 1982-12-22 | Hyperüretische Mittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE24997T1 true ATE24997T1 (de) | 1987-02-15 |
Family
ID=26990347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT82111893T ATE24997T1 (de) | 1982-01-04 | 1982-12-22 | Hyperueretische mittel. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0083779B1 (de) |
| JP (1) | JPS58150510A (de) |
| AT (1) | ATE24997T1 (de) |
| AU (1) | AU564588B2 (de) |
| CA (1) | CA1183456A (de) |
| DE (1) | DE3275160D1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL109570A0 (en) * | 1993-05-17 | 1994-08-26 | Fujisawa Pharmaceutical Co | Guanidine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof |
| DE19600721A1 (de) * | 1996-01-12 | 1997-07-17 | Hoechst Ag | Verwendung von Inhibitoren des Carboanhydratase (CAH) zum Herstellen eines Medikaments zur Behandlung von Krebs |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3268406A (en) * | 1961-10-12 | 1966-08-23 | Merck & Co Inc | Compositions and method of using (3-amino-pyrazinoyl) guanidines |
| US3240780A (en) * | 1963-12-23 | 1966-03-15 | Merck & Co Inc | Amino-pyrazinoyl guanidines |
| US3575975A (en) * | 1968-07-25 | 1971-04-20 | Merck & Co Inc | Process for the preparation of 3-aminopyrazinoylureas |
| NL7600500A (nl) * | 1975-02-03 | 1976-08-05 | Merck & Co Inc | Werkwijze voor het bereiden van farmaceutische preparaten. |
| AU522049B2 (en) * | 1978-01-13 | 1982-05-13 | Van Scott, Eugene Joseph | Treatment of psoriasis |
-
1982
- 1982-12-22 AT AT82111893T patent/ATE24997T1/de not_active IP Right Cessation
- 1982-12-22 EP EP82111893A patent/EP0083779B1/de not_active Expired
- 1982-12-22 DE DE8282111893T patent/DE3275160D1/de not_active Expired
- 1982-12-23 CA CA000418427A patent/CA1183456A/en not_active Expired
- 1982-12-24 AU AU91906/82A patent/AU564588B2/en not_active Ceased
- 1982-12-29 JP JP57234891A patent/JPS58150510A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS58150510A (ja) | 1983-09-07 |
| DE3275160D1 (en) | 1987-02-26 |
| EP0083779B1 (de) | 1987-01-21 |
| AU9190682A (en) | 1983-07-14 |
| EP0083779A1 (de) | 1983-07-20 |
| AU564588B2 (en) | 1987-08-20 |
| JPH0557242B2 (de) | 1993-08-23 |
| CA1183456A (en) | 1985-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |