ATE250047T1 - Verfahren zur herstellung von aminoepoxiden aus aminoaldehyden und einem in situ erzeugten halogenomethylorganometallischen reagenz - Google Patents

Verfahren zur herstellung von aminoepoxiden aus aminoaldehyden und einem in situ erzeugten halogenomethylorganometallischen reagenz

Info

Publication number: ATE250047T1
Authority: AT; Austria
Prior art keywords: reagent; halogenomethylorganometallic; aminoepoxides; aminoaldehydes; producing
Prior art date: 1996-12-31

Application number

AT97953210T

Other languages

English (en)

Inventor

Chin Liu

John S Ng

James R Behling

Arthur L Campbell

Original Assignee

Searle & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-31

Filing date

1997-12-19

Publication date

2003-10-15

1997-12-19 Application filed by Searle & Co filed Critical Searle & Co

2003-10-15 Application granted granted Critical

2003-10-15 Publication of ATE250047T1 publication Critical patent/ATE250047T1/de

Links

239000003153 chemical reaction reagent Substances 0.000 title abstract 6
238000011065 in-situ storage Methods 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
239000007795 chemical reaction product Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000002524 organometallic group Chemical group 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Epoxy Compounds (AREA)
Epoxy Resins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Phenolic Resins Or Amino Resins (AREA)

AT97953210T 1996-12-31 1997-12-19 Verfahren zur herstellung von aminoepoxiden aus aminoaldehyden und einem in situ erzeugten halogenomethylorganometallischen reagenz ATE250047T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US3380196P	1996-12-31	1996-12-31
PCT/US1997/022989 WO1998029401A1 (en)	1996-12-31	1997-12-19	Aminoepoxides from aminoaldehydes and in-situ formed halomethyl organometallic reagent

Publications (1)

Publication Number	Publication Date
ATE250047T1 true ATE250047T1 (de)	2003-10-15

Family

ID=21872516

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97953210T ATE250047T1 (de)	1996-12-31	1997-12-19	Verfahren zur herstellung von aminoepoxiden aus aminoaldehyden und einem in situ erzeugten halogenomethylorganometallischen reagenz

Country Status (21)

Country	Link
US (1)	US6127556A (de)
EP (1)	EP0970066B1 (de)
JP (1)	JP3710488B2 (de)
KR (1)	KR100523190B1 (de)
CN (1)	CN1247535A (de)
AT (1)	ATE250047T1 (de)
AU (1)	AU733905B2 (de)
BR (1)	BR9714129A (de)
CA (1)	CA2276488C (de)
CY (1)	CY2521B1 (de)
CZ (1)	CZ297432B6 (de)
DE (1)	DE69725014T2 (de)
ES (1)	ES2207760T3 (de)
IL (1)	IL130609A (de)
NO (1)	NO320276B1 (de)
NZ (1)	NZ336451A (de)
PL (1)	PL334387A1 (de)
PT (1)	PT970066E (de)
RO (1)	RO120135B1 (de)
RU (1)	RU2194045C2 (de)
WO (1)	WO1998029401A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6123662A (en)	1998-07-13	2000-09-26	Acorn Cardiovascular, Inc.	Cardiac disease treatment and device
US6085754A (en)	1998-07-13	2000-07-11	Acorn Cardiovascular, Inc.	Cardiac disease treatment method
US6230714B1 (en) *	1998-11-18	2001-05-15	Acorn Cardiovascular, Inc.	Cardiac constraint with prior venus occlusion methods
US6169922B1 (en)	1998-11-18	2001-01-02	Acorn Cardiovascular, Inc.	Defibrillating cardiac jacket with interwoven electrode grids
US6155972A (en)	1999-02-02	2000-12-05	Acorn Cardiovascular, Inc.	Cardiac constraint jacket construction
US6174279B1 (en)	1999-09-21	2001-01-16	Acorn Cardiovascular, Inc.	Cardiac constraint with tension indicator
US6193648B1 (en)	1999-09-21	2001-02-27	Acorn Cardiovascular, Inc.	Cardiac constraint with draw string tensioning
US6179791B1 (en)	1999-09-21	2001-01-30	Acorn Cardiovascular, Inc.	Device for heart measurement
US6293906B1 (en)	2000-01-14	2001-09-25	Acorn Cardiovascular, Inc.	Delivery of cardiac constraint jacket
AU2001252958A1 (en)	2000-03-23	2001-10-03	Elan Pharmaceuticals, Inc.	Compounds and methods to treat alzheimer's disease
PE20020276A1 (es)	2000-06-30	2002-04-06	Elan Pharm Inc	COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER
DE60116313T2 (de)	2000-06-30	2006-08-31	Elan Pharmaceuticals, Inc., San Francisco	Verbindungen zur behandlung der alzheimerischen krankheit
US6846813B2 (en)	2000-06-30	2005-01-25	Pharmacia & Upjohn Company	Compounds to treat alzheimer's disease
EP1666452A2 (de)	2000-06-30	2006-06-07	Elan Pharmaceuticals, Inc.	Verbindungen zur Behandlung der Alzheimerischen Krankheit
US6755779B2 (en)	2000-12-01	2004-06-29	Acorn Cardiovascular, Inc.	Apparatus and method for delivery of cardiac constraint jacket
US6575921B2 (en)	2001-02-09	2003-06-10	Acorn Cardiovascular, Inc.	Device for heart measurement
WO2003002122A1 (en)	2001-06-27	2003-01-09	Elan Pharmaceuticals, Inc.	Beta-hydroxyamine derivatives useful in treatment of alzheimer's disease
US6696594B2 (en)	2002-05-13	2004-02-24	Saudi Basic Industries Corporation	Process for the conversion of aldehydes to esters
PT2439205E (pt)	2006-12-29	2015-07-16	Abbvie Deutschland	Compostos de carboxamida e seus usos como inibidores de calpaína
WO2009136365A1 (en) *	2008-05-08	2009-11-12	Ranbaxy Laboratories Limited	Process for the preparation of 3,4-epoxy-2-amino-1-substituted butane derivatives and intermediate compounds thereof
CA2736600C (fr) *	2008-09-24	2017-03-21	Zach System	Procede de preparation de nebivolol

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4268688A (en) *	1973-02-16	1981-05-19	Monsanto Company	Asymmetric hydroformylation process
DE3711911A1 (de) *	1987-04-08	1988-10-20	Bayer Ag	Optisch aktive (alpha)-aminoaldehyde, verfahren zu ihrer herstellung und ihre verwendung zur stereoselektiven herstellung optisch aktiver ss-aminoalkohole
AU4253193A (en) *	1992-05-20	1993-12-13	G.D. Searle & Co.	Urea-containing hydroxyethylamine compounds as retroviral protease inhibitors
PT855388E (pt) *	1993-11-23	2002-07-31	Searle & Co	Metodo para fazer intermediarios uteis na sintese de inibidores de protease retroviral
CA2137406C (en) *	1994-12-06	2005-09-13	Pierre Louis Beaulieu	Process for key intermediates for hiv protease inhibitors

1997
- 1997-12-16 US US08/991,598 patent/US6127556A/en not_active Expired - Fee Related
- 1997-12-19 CN CN97181934A patent/CN1247535A/zh active Pending
- 1997-12-19 CA CA002276488A patent/CA2276488C/en not_active Expired - Fee Related
- 1997-12-19 PT PT97953210T patent/PT970066E/pt unknown
- 1997-12-19 AU AU57008/98A patent/AU733905B2/en not_active Ceased
- 1997-12-19 KR KR10-1999-7005958A patent/KR100523190B1/ko not_active Expired - Fee Related
- 1997-12-19 WO PCT/US1997/022989 patent/WO1998029401A1/en not_active Ceased
- 1997-12-19 EP EP97953210A patent/EP0970066B1/de not_active Expired - Lifetime
- 1997-12-19 CZ CZ0230599A patent/CZ297432B6/cs not_active IP Right Cessation
- 1997-12-19 JP JP53006298A patent/JP3710488B2/ja not_active Expired - Fee Related
- 1997-12-19 NZ NZ336451A patent/NZ336451A/xx unknown
- 1997-12-19 PL PL97334387A patent/PL334387A1/xx not_active Application Discontinuation
- 1997-12-19 ES ES97953210T patent/ES2207760T3/es not_active Expired - Lifetime
- 1997-12-19 RO RO99-00756A patent/RO120135B1/ro unknown
- 1997-12-19 IL IL13060997A patent/IL130609A/xx not_active IP Right Cessation
- 1997-12-19 AT AT97953210T patent/ATE250047T1/de not_active IP Right Cessation
- 1997-12-19 RU RU99116620/04A patent/RU2194045C2/ru not_active IP Right Cessation
- 1997-12-19 BR BR9714129-1A patent/BR9714129A/pt not_active Application Discontinuation
- 1997-12-19 DE DE69725014T patent/DE69725014T2/de not_active Expired - Fee Related
1999
- 1999-06-29 NO NO19993223A patent/NO320276B1/no unknown
2005
- 2005-03-16 CY CY0500018A patent/CY2521B1/xx unknown

Also Published As

Publication number	Publication date
IL130609A0 (en)	2000-06-01
CZ230599A3 (cs)	1999-11-17
EP0970066B1 (de)	2003-09-17
DE69725014D1 (de)	2003-10-23
IL130609A (en)	2003-04-10
PT970066E (pt)	2004-02-27
KR100523190B1 (ko)	2005-10-21
KR20000069808A (ko)	2000-11-25
CN1247535A (zh)	2000-03-15
DE69725014T2 (de)	2004-06-09
CZ297432B6 (cs)	2006-12-13
CA2276488C (en)	2006-07-18
US6127556A (en)	2000-10-03
BR9714129A (pt)	2000-02-29
JP3710488B2 (ja)	2005-10-26
AU733905B2 (en)	2001-05-31
CA2276488A1 (en)	1998-07-09
NO993223L (no)	1999-08-24
NO993223D0 (no)	1999-06-29
NO320276B1 (no)	2005-11-21
RO120135B1 (ro)	2005-09-30
EP0970066A1 (de)	2000-01-12
WO1998029401A1 (en)	1998-07-09
ES2207760T3 (es)	2004-06-01
CY2521B1 (en)	2006-02-08
NZ336451A (en)	2000-09-29
AU5700898A (en)	1998-07-31
PL334387A1 (en)	2000-02-28
JP2001507693A (ja)	2001-06-12
RU2194045C2 (ru)	2002-12-10

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2004-06-15

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2009-09-15

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