ATE250922T1 - Verfahren und vorrichtung zur inhalation teilchenförmiger medikamente - Google Patents

Verfahren und vorrichtung zur inhalation teilchenförmiger medikamente

Info

Publication number
ATE250922T1
ATE250922T1 AT97915445T AT97915445T ATE250922T1 AT E250922 T1 ATE250922 T1 AT E250922T1 AT 97915445 T AT97915445 T AT 97915445T AT 97915445 T AT97915445 T AT 97915445T AT E250922 T1 ATE250922 T1 AT E250922T1
Authority
AT
Austria
Prior art keywords
medications
inhalator
inhaling
particle
medicament
Prior art date
Application number
AT97915445T
Other languages
English (en)
Inventor
Oort Michiel Van
Mark J Sacchetti
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10791297&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE250922(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE250922T1 publication Critical patent/ATE250922T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Otolaryngology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT97915445T 1996-03-29 1997-03-25 Verfahren und vorrichtung zur inhalation teilchenförmiger medikamente ATE250922T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9606677.4A GB9606677D0 (en) 1996-03-29 1996-03-29 Process and device
PCT/EP1997/001560 WO1997036574A1 (en) 1996-03-29 1997-03-25 Process and device for inhalation of particulate medicaments

Publications (1)

Publication Number Publication Date
ATE250922T1 true ATE250922T1 (de) 2003-10-15

Family

ID=10791297

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97915445T ATE250922T1 (de) 1996-03-29 1997-03-25 Verfahren und vorrichtung zur inhalation teilchenförmiger medikamente

Country Status (12)

Country Link
US (2) US20010018916A1 (de)
EP (1) EP0904056B1 (de)
JP (1) JP2000507862A (de)
AT (1) ATE250922T1 (de)
AU (1) AU724500B2 (de)
CA (1) CA2250217A1 (de)
DE (1) DE69725308T2 (de)
DK (1) DK0904056T3 (de)
ES (1) ES2208889T3 (de)
GB (1) GB9606677D0 (de)
PT (1) PT904056E (de)
WO (1) WO1997036574A1 (de)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020052310A1 (en) 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
US6254854B1 (en) 1996-05-24 2001-07-03 The Penn Research Foundation Porous particles for deep lung delivery
USRE37053E1 (en) 1996-05-24 2001-02-13 Massachusetts Institute Of Technology Particles incorporating surfactants for pulmonary drug delivery
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US5855913A (en) * 1997-01-16 1999-01-05 Massachusetts Instite Of Technology Particles incorporating surfactants for pulmonary drug delivery
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US6503480B1 (en) 1997-05-23 2003-01-07 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
AU5719798A (en) 1996-12-31 1998-07-31 Inhale Therapeutic Systems, Inc. Processes for spray drying aqueous suspensions of hydrophobic drugs with hydrophilic excipients and compositions prepared by such processes
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
US6946117B1 (en) 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
AU756693B2 (en) * 1997-09-29 2003-01-23 Novartis Ag Stabilized bioactive preparations and methods of use
CA2231968A1 (en) * 1998-03-11 1999-09-11 Smoke-Stop, A Partnership Consisting Of Art Slutsky Method of producing a nicotine medicament
ATE228823T1 (de) 1998-04-18 2002-12-15 Glaxo Group Ltd Pharmazeutische aerosolformulierung
GB9808802D0 (en) * 1998-04-24 1998-06-24 Glaxo Group Ltd Pharmaceutical formulations
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
US6660715B2 (en) 1998-11-19 2003-12-09 Massachusetts Institute Of Technology Nonaqueous solutions and suspensions of macromolecules for pulmonary delivery
PT1280520E (pt) 2000-05-10 2014-12-16 Novartis Ag Pós à base de fosfolípidos para administração de fármacos
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
FI20002215A0 (fi) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit
FI20002216A0 (fi) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit astman hoitoon
US6595210B2 (en) 2000-11-27 2003-07-22 Unisia Jecs Corporation Inhalator for administering powder composition
JP2005504715A (ja) 2000-12-29 2005-02-17 アドバンスト インハレーション リサーチ,インコーポレイテッド 持続放出特性を有する吸入用粒子
JP2005503425A (ja) 2001-05-24 2005-02-03 アレックザ モレキュラー デリヴァリー コーポレイション 所定の吸入ルートによる薬剤エステルの送出
US7090830B2 (en) 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
WO2002094238A1 (en) * 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of anti-migraine compounds through an inhalation route
WO2002094241A1 (en) * 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of compounds for the treatment of migraine through an inhalation route
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
ATE415155T1 (de) 2001-05-24 2008-12-15 Alexza Pharmaceuticals Inc Verabreichung von alprazolam, estazolam, midazolam oder triazolam durch inhalation
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US20030051728A1 (en) 2001-06-05 2003-03-20 Lloyd Peter M. Method and device for delivering a physiologically active compound
WO2002094242A1 (en) 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of rizatriptan or zolmitriptan through an inhalation route
US7498019B2 (en) 2001-05-24 2009-03-03 Alexza Pharmaceuticals, Inc. Delivery of compounds for the treatment of headache through an inhalation route
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
WO2003015747A1 (en) 2001-08-13 2003-02-27 Genomed, Llc Method to treat pulmonary hypoplasia in the newborn
KR100951750B1 (ko) 2001-11-01 2010-04-09 노바르티스 아게 분무 건조 방법 및 그 조성물
WO2003041693A1 (en) 2001-11-09 2003-05-22 Alexza Molecular Delivery Corporation Delivery of diazepam through an inhalation route
AU2002352836B2 (en) 2001-11-20 2005-09-29 Alkermes, Inc. Improved particulate compositions for pulmonary delivery
JP2005511629A (ja) * 2001-11-20 2005-04-28 アドバンスト インハレーション リサーチ,インコーポレイテッド 持続作用生成物送達用組成物
PT1458360E (pt) 2001-12-19 2011-07-13 Novartis Ag Derivados de indole como agonistas do recetor s1p1
AU2003218307B8 (en) * 2002-03-20 2006-08-31 Alkermes, Inc. Pulmonary delivery for levodopa
US7582284B2 (en) 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
WO2003092654A1 (en) 2002-05-02 2003-11-13 President And Fellows Of Harvard College Formulations limiting spread of pulmonary infections
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
US7185647B2 (en) * 2002-08-16 2007-03-06 Schering Corporation Determination of smoothness of canisters containing inhalable medicaments
US7550133B2 (en) 2002-11-26 2009-06-23 Alexza Pharmaceuticals, Inc. Respiratory drug condensation aerosols and methods of making and using them
US20050044164A1 (en) * 2002-12-23 2005-02-24 O'farrell Robert Mobile data and software update system and method
WO2004092982A2 (en) * 2003-04-07 2004-10-28 Dexterra, Inc. System and method for context sensitive mobile data and software update
CA2522231A1 (en) * 2003-04-14 2004-10-21 Vectura Ltd Pharmaceutical compositions comprising apomorphine for pulmonary inhalation
US20050207983A1 (en) 2004-03-05 2005-09-22 Pulmatrix, Inc. Formulations decreasing particle exhalation
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
EP1781360A1 (de) 2004-08-12 2007-05-09 Alexza Pharmaceuticals, Inc. Aerosol-arzneiabgabevorrichtung mit perkussiv aktivierten wärmepackungen
US8627821B2 (en) 2005-01-10 2014-01-14 Pulmatrix, Inc. Method and device for decreasing contamination
WO2008097664A1 (en) 2007-02-11 2008-08-14 Map Pharmaceuticals, Inc. Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile
US20080202627A1 (en) * 2007-02-23 2008-08-28 Mas Gregory V Dosing System and Method
WO2008112661A2 (en) 2007-03-09 2008-09-18 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
CA2729644C (en) * 2008-07-18 2018-05-29 Prosonix Limited Process for improving crystallinity
WO2010063286A2 (en) 2008-12-04 2010-06-10 Nordicaryan Aps A hand-held inhaler
ES2625260T5 (es) 2009-03-26 2020-07-29 Pulmatrix Operating Co Inc Formulaciones de polvo seco y métodos para el tratamiento de enfermedades pulmonares
WO2011057235A2 (en) * 2009-11-09 2011-05-12 Virginia Commonwealth University Improved delivery of submicrometer and nonometer aerosols to the lungs using hygroscopic excipients or dual stream nasal delivery
WO2012030645A1 (en) 2010-08-30 2012-03-08 Pulmatrix, Inc. Respirably dry powder comprising calcium lactate, sodium chloride and leucine
CN103200938B (zh) 2010-08-30 2018-07-31 普马特里克斯营业公司 干燥粉末配方及用于治疗肺部疾病的方法
EP2613829B1 (de) * 2010-09-06 2022-06-29 Chiesi Farmaceutici S.p.A. Inhaliergerät mit abgemessener dosis
BR112013007304B1 (pt) 2010-09-29 2021-12-14 Pulmatrix, Inc. Pós secos de cátion de metal monovalente para inalação
PT3470057T (pt) 2010-09-29 2021-12-03 Pulmatrix Operating Co Inc Pós secos catiónicos compreendendo sais de magnésio
US9119773B2 (en) 2011-06-27 2015-09-01 Board Of Regents, The University Of Texas System Toroidal pharmaceutical formulations
CN107596518B (zh) 2012-02-29 2021-04-23 普马特里克斯营业公司 可吸入干粉剂
AU2014248455B2 (en) 2013-04-01 2018-12-06 Pulmatrix Operating Company, Inc. Tiotropium dry powders
MX392636B (es) 2014-10-31 2025-03-24 Glaxosmithkline Ip Dev Ltd Formulacion en polvo.
US12214118B2 (en) 2018-02-02 2025-02-04 Alexza Pharmaceuticals, Inc. Electrical condensation aerosol device
GB2573297A (en) * 2018-04-30 2019-11-06 Mexichem Fluor Sa De Cv Pharmaceutical composition
EP3563894B1 (de) 2018-05-04 2021-12-22 Boehringer Ingelheim International GmbH Zerstäuber und behälter
WO2019236649A1 (en) * 2018-06-07 2019-12-12 3M Innovative Properties Company Fluticasone and vilanterol formulation and inhaler

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4161516A (en) * 1975-07-25 1979-07-17 Fisons Limited Composition for treating airway disease
US4147766A (en) * 1976-06-09 1979-04-03 Armour Pharmaceutical Company Macrospherical particles of anti-perspirants
EP0072046B1 (de) * 1981-07-24 1986-01-15 FISONS plc Inhalierbare Arzneimittel, Verfahren zu deren Herstellung und pharmazeutische Formulierungen diese enthaltend
GB2146531B (en) * 1983-09-15 1987-04-29 Stc Plc Controlled release system
US4818542A (en) * 1983-11-14 1989-04-04 The University Of Kentucky Research Foundation Porous microspheres for drug delivery and methods for making same
US4865789A (en) * 1983-11-14 1989-09-12 Akzo Nv Method for making porous structures
US4690825A (en) * 1985-10-04 1987-09-01 Advanced Polymer Systems, Inc. Method for delivering an active ingredient by controlled time release utilizing a novel delivery vehicle which can be prepared by a process utilizing the active ingredient as a porogen
GB8601100D0 (en) * 1986-01-17 1986-02-19 Cosmas Damian Ltd Drug delivery system
US4741872A (en) * 1986-05-16 1988-05-03 The University Of Kentucky Research Foundation Preparation of biodegradable microspheres useful as carriers for macromolecules
GB8713263D0 (en) * 1987-06-05 1987-07-08 Unilever Plc Spheroidal silica
JPH0762054B2 (ja) * 1987-10-13 1995-07-05 倉敷紡績株式会社 架橋重合体粒子
US4855144A (en) * 1987-10-23 1989-08-08 Advanced Polymer Systems Synthetic melanin aggregates
US4937081A (en) * 1988-01-14 1990-06-26 Daicel Chemical Industries Ltd. Process for producing porous, spherical particles
US5023080A (en) * 1988-06-17 1991-06-11 Basic Bio Systems, Inc. Time release protein
NZ292980A (en) * 1994-09-29 1999-02-25 Andaris Ltd Smooth, spherical water-soluble microparticles as therapeutic or diagnostic vehicles

Also Published As

Publication number Publication date
US20030005927A1 (en) 2003-01-09
EP0904056B1 (de) 2003-10-01
PT904056E (pt) 2004-02-27
DE69725308T2 (de) 2004-08-05
DE69725308D1 (de) 2003-11-06
CA2250217A1 (en) 1997-10-09
AU2292197A (en) 1997-10-22
ES2208889T3 (es) 2004-06-16
AU724500B2 (en) 2000-09-21
GB9606677D0 (en) 1996-06-05
EP0904056A1 (de) 1999-03-31
JP2000507862A (ja) 2000-06-27
DK0904056T3 (da) 2004-01-19
WO1997036574A1 (en) 1997-10-09
US20010018916A1 (en) 2001-09-06

Similar Documents

Publication Publication Date Title
ATE250922T1 (de) Verfahren und vorrichtung zur inhalation teilchenförmiger medikamente
PT1019022E (pt) Microparticulas perfuradas e metodos de utilizacao
GEP20043258B (en) Systems and Methods for Aerosolizing Pharmaceutical Formulations
DE69927139D1 (de) Lungendosiersystem
ATE545442T1 (de) Medizinische vorrichtung zur inhalation von aerosolisiertem arzneimittel mit heliox
AT384552B (de) Inhalationsgeraet zur dosierung und verteilung von festkoerpern in die atemluft
Scheuch et al. An approach to deposition and clearance measurements in human airways
ATE251447T1 (de) Pharmazeutische zubereitungen zur inhalation eines opioids
EP1224003B8 (de) Mundstück für eine Inhalationstherapievorrichtung zum Gebrauch durch von Sauerstoff abhängige Patienten
GB9806462D0 (en) Improved compositions for inhalation
ATE276722T1 (de) Vorrichtung zur organisation des kombinierten gebrauchs von lokalen aerosolen und oralen medikamenten
RU2012363C1 (ru) Устройство в.а.старцева для насыщения воздуха лекарственными веществами
SE9402383L (sv) Förfarande och anordning för att införa en aktiv substans till en persons andningssystem

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0904056

Country of ref document: EP

RZN Patent revoked