ATE251447T1 - Pharmazeutische zubereitungen zur inhalation eines opioids - Google Patents

Pharmazeutische zubereitungen zur inhalation eines opioids

Info

Publication number: ATE251447T1
Authority: AT; Austria
Prior art keywords: opioids; dry powder; inhalation; administered; opioid
Prior art date: 1998-12-11

Application number

AT98962686T

Other languages

English (en)

Inventor

Volcmar Verkerk

Marianne Elisabeth Blom-Ross

Dort Karin Van

Vos Dick De

Original Assignee

Pharmachemie Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-11

Filing date

1998-12-11

Publication date

2003-10-15

1998-12-11 Application filed by Pharmachemie Bv filed Critical Pharmachemie Bv

2003-10-15 Application granted granted Critical

2003-10-15 Publication of ATE251447T1 publication Critical patent/ATE251447T1/de

Links

239000000825 pharmaceutical preparation Substances 0.000 title 1
229940005483 opioid analgesics Drugs 0.000 abstract 4
239000000843 powder Substances 0.000 abstract 4
BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 abstract 2
206010013975 Dyspnoeas Diseases 0.000 abstract 1
238000010521 absorption reaction Methods 0.000 abstract 1
210000004072 lung Anatomy 0.000 abstract 1
229960005181 morphine Drugs 0.000 abstract 1
210000002345 respiratory system Anatomy 0.000 abstract 1
230000009885 systemic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/12—Mucolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pulmonology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Otolaryngology (AREA)
Pain & Pain Management (AREA)
Emergency Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT98962686T 1998-12-11 1998-12-11 Pharmazeutische zubereitungen zur inhalation eines opioids ATE251447T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/NL1998/000713 WO2000035417A1 (en)	1998-12-11	1998-12-11	Pharmaceutical preparation for inhalation of an opioid

Publications (1)

Publication Number	Publication Date
ATE251447T1 true ATE251447T1 (de)	2003-10-15

Family

ID=19866466

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98962686T ATE251447T1 (de)	1998-12-11	1998-12-11	Pharmazeutische zubereitungen zur inhalation eines opioids

Country Status (11)

Country	Link
US (1)	US20010041164A1 (de)
EP (1)	EP1137398B1 (de)
JP (1)	JP2002532405A (de)
AT (1)	ATE251447T1 (de)
AU (1)	AU1786199A (de)
CA (1)	CA2354576C (de)
DE (1)	DE69818872T2 (de)
DK (1)	DK1137398T3 (de)
ES (1)	ES2207867T3 (de)
IL (2)	IL143576A0 (de)
WO (1)	WO2000035417A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE60231611D1 (de) *	2001-05-24	2009-04-30	Alexza Pharmaceuticals Inc	Verabreichung von opioiden durch inhalation
US7766013B2 (en)	2001-06-05	2010-08-03	Alexza Pharmaceuticals, Inc.	Aerosol generating method and device
US7585493B2 (en)	2001-05-24	2009-09-08	Alexza Pharmaceuticals, Inc.	Thin-film drug delivery article and method of use
US7458374B2 (en)	2002-05-13	2008-12-02	Alexza Pharmaceuticals, Inc.	Method and apparatus for vaporizing a compound
JP2005503425A (ja)	2001-05-24	2005-02-03	アレックザモレキュラーデリヴァリーコーポレイション	所定の吸入ルートによる薬剤エステルの送出
US7090830B2 (en)	2001-05-24	2006-08-15	Alexza Pharmaceuticals, Inc.	Drug condensation aerosols and kits
US20070122353A1 (en)	2001-05-24	2007-05-31	Hale Ron L	Drug condensation aerosols and kits
GB0219513D0 (en) *	2002-08-21	2002-10-02	Norton Healthcare Ltd	Inhalation compositions including coarse carrier
ATE520405T1 (de) *	2002-08-21	2011-09-15	Norton Healthcare Ltd	Inhalationszusammensetzung
WO2004075879A1 (en) *	2003-02-28	2004-09-10	Delex Therapeutics Inc.	Opioid delivery system
US20040234699A1 (en)	2003-05-21	2004-11-25	Alexza Molecular Delivery Corporation	Methods of controlling uniformity of substrate temperature and self-contained heating unit and drug-supply unit employing same
US7540286B2 (en)	2004-06-03	2009-06-02	Alexza Pharmaceuticals, Inc.	Multiple dose condensation aerosol devices and methods of forming condensation aerosols
EP2246086A3 (de)	2004-08-12	2012-11-21	Alexza Pharmaceuticals, Inc.	Aerosolverabreichungsvorrichtung mit Schlag gezündete Heizeinheit
WO2006124556A2 (en) *	2005-05-13	2006-11-23	Glaxo Group Limited	Inhalable pharmaceutical formulations employing lactose anhydrate and methods of administering the same
EP2121088B1 (de)	2007-03-09	2016-07-13	Alexza Pharmaceuticals, Inc.	Erhitzungseinheit zur verwendung in einer arzneimittelabgabevorrichtung
EP2389159A1 (de) *	2009-01-22	2011-11-30	Noramco, Inc.	Verfahren zur herstellung von opioid-partikeln und so hergestellte zusammensetzungen
US12214118B2 (en)	2018-02-02	2025-02-04	Alexza Pharmaceuticals, Inc.	Electrical condensation aerosol device

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9001635D0 (en) *	1990-01-24	1990-03-21	Ganderton David	Aerosol carriers
GB9103302D0 (en) *	1991-02-16	1991-04-03	Smithkline Beecham Plc	Pharmaceutical formulations
US6017963A (en) *	1995-11-14	2000-01-25	Euro-Celtique, S.A.	Formulation for intranasal administration
GB9606188D0 (en) *	1996-03-23	1996-05-29	Danbiosyst Uk	Pollysaccharide microspheres for the pulmonary delivery of drugs
SE9700135D0 (sv) *	1997-01-20	1997-01-20	Astra Ab	New formulation

1998
- 1998-12-11 DE DE69818872T patent/DE69818872T2/de not_active Expired - Fee Related
- 1998-12-11 DK DK98962686T patent/DK1137398T3/da active
- 1998-12-11 EP EP98962686A patent/EP1137398B1/de not_active Expired - Lifetime
- 1998-12-11 WO PCT/NL1998/000713 patent/WO2000035417A1/en not_active Ceased
- 1998-12-11 IL IL14357698A patent/IL143576A0/xx not_active IP Right Cessation
- 1998-12-11 CA CA002354576A patent/CA2354576C/en not_active Expired - Fee Related
- 1998-12-11 AT AT98962686T patent/ATE251447T1/de not_active IP Right Cessation
- 1998-12-11 AU AU17861/99A patent/AU1786199A/en not_active Withdrawn
- 1998-12-11 JP JP2000587738A patent/JP2002532405A/ja active Pending
- 1998-12-11 ES ES98962686T patent/ES2207867T3/es not_active Expired - Lifetime
2001
- 2001-06-05 IL IL143576A patent/IL143576A/en unknown
- 2001-06-11 US US09/877,078 patent/US20010041164A1/en not_active Abandoned

Also Published As

Publication number	Publication date
WO2000035417A1 (en)	2000-06-22
IL143576A0 (en)	2002-04-21
IL143576A (en)	2006-10-31
CA2354576A1 (en)	2000-06-22
US20010041164A1 (en)	2001-11-15
JP2002532405A (ja)	2002-10-02
CA2354576C (en)	2008-10-14
EP1137398B1 (de)	2003-10-08
ES2207867T3 (es)	2004-06-01
DE69818872T2 (de)	2004-05-19
EP1137398A1 (de)	2001-10-04
DK1137398T3 (da)	2004-02-02
AU1786199A (en)	2000-07-03
DE69818872D1 (de)	2003-11-13

Legal Events

Date

Code

Title

Description

2004-04-15

UEP

Publication of translation of european patent specification

Ref document number: 1137398

Country of ref document: EP

2009-09-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69818872D1 (de)	2003-11-13	Pharmazeutische zubereitungen zur inhalation eines opioids
CA2146954A1 (en)	1996-10-13	Breath activated nicotine inhalers
Anderson	2005	History of aerosol therapy: liquid nebulization to MDIs to DPIs
EE03221B1 (et)	1999-10-15	Inhaleeritavad ravimpreparaadid, nende valmistamise protsess ja inhalaator nende kasutamiseks
US20190046436A1 (en)	2019-02-14	Nicotine formulation and aerosols
DK1019021T3 (da)	2003-11-10	Stabiliserede præparater til anvendelse i inhalatorer med afmålt dosis
EA200100338A1 (ru)	2001-10-22	Способ и устройство для введения действующего вещества в виде аэрозоли в легкие пациента
DE69921785D1 (de)	2004-12-16	Nikotininhalator
TR200002692T2 (tr)	2001-02-21	Aerosol haline getirilen aktif maddenin verilmesi.
TNSN04149A1 (en)	2007-03-12	Pressurised metered dose inhalers containing solutions of beta-2 agonists
SE9700423D0 (sv)	1997-02-07	Disposable inhaler
Newman et al.	1987	The nasal distribution of metered does inhalers
JP2001527442A (ja)	2001-12-25	ハロセラピーの投与方法
BR0011343A (pt)	2002-03-12	Dispositivo de distribuição de medicamento,e,métodos de administrar um medicamento por inalação,e de,tratamento de um paciente com distúrbio respiratório
TW200607538A (en)	2006-03-01	Medicament inhaler device
US11006661B2 (en)	2021-05-18	Cigarette-like device for administration of substances
FI962665A0 (fi)	1996-06-27	Menetelmä ja sovitelma intuboidun potilaan hengityMenetelmä ja sovitelma intuboidun potilaan hengityskaasun käsittelemiseksi skaasun käsittelemiseksi
WO2004082633A3 (en)	2005-03-17	A method of treating a systemic disease
NO20021681L (no)	2002-06-03	Anordning for avlevering av medikament, med fuktighetsbestandig belegg
Hofmann et al.	1997	Aerosolized amiloride: dose effect on nasal bioelectric properties, pharmacokinetics, and effect on sputum expectoration in patients with cystic fibrosis
ATE271852T1 (de)	2004-08-15	Verbesserte inhalationspräparate
RU2012363C1 (ru)	1994-05-15	Устройство в.а.старцева для насыщения воздуха лекарственными веществами
KIM et al.	2000	The effect of patient education on correct use of metered dose inhalers in patients with asthma
EP1110547A3 (de)	2001-10-04	Helium und Neon als Hilfsstoffe zur Wirkstoffverabreichung mittels Inhalator
CN101146563B (zh)	2011-01-05	气雾剂形式的药品的给药设备