ATE251611T1 - Additionsreaktion mit asymmetrischem konjugat - Google Patents
Additionsreaktion mit asymmetrischem konjugatInfo
- Publication number
- ATE251611T1 ATE251611T1 AT97936396T AT97936396T ATE251611T1 AT E251611 T1 ATE251611 T1 AT E251611T1 AT 97936396 T AT97936396 T AT 97936396T AT 97936396 T AT97936396 T AT 97936396T AT E251611 T1 ATE251611 T1 AT E251611T1
- Authority
- AT
- Austria
- Prior art keywords
- addition reaction
- asymmetric conjugate
- asymmetric
- conjugate
- synthesis
- Prior art date
Links
- 238000007259 addition reaction Methods 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 238000003786 synthesis reaction Methods 0.000 abstract 2
- 239000002308 endothelin receptor antagonist Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C07F7/1872—Preparation; Treatments not provided for in C07F7/20
- C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2361996P | 1996-08-09 | 1996-08-09 | |
| GBGB9617949.4A GB9617949D0 (en) | 1996-08-28 | 1996-08-28 | An asymmetric conjugate addition reaction |
| US2823396P | 1996-10-10 | 1996-10-10 | |
| GBGB9624467.8A GB9624467D0 (en) | 1996-11-25 | 1996-11-25 | An asymmetric conjugate addition reaction |
| PCT/US1997/013725 WO1998006698A1 (en) | 1996-08-09 | 1997-08-05 | An asymmetric conjugate addition reaction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE251611T1 true ATE251611T1 (de) | 2003-10-15 |
Family
ID=27451512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97936396T ATE251611T1 (de) | 1996-08-09 | 1997-08-05 | Additionsreaktion mit asymmetrischem konjugat |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0923556B1 (de) |
| JP (1) | JP3262805B2 (de) |
| AT (1) | ATE251611T1 (de) |
| AU (1) | AU732213B2 (de) |
| CA (1) | CA2262837C (de) |
| DE (1) | DE69725455T2 (de) |
| ES (1) | ES2207747T3 (de) |
| WO (1) | WO1998006698A1 (de) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN167395B (de) * | 1987-07-21 | 1990-10-20 | Hoffmann La Roche | |
| FI942059L (fi) * | 1991-11-05 | 1994-07-04 | Smithkline Beecham Corp | Endoteliinireseptoreiden antagonisteja |
| US5420133A (en) | 1993-03-19 | 1995-05-30 | Merck & Co., Inc. | Quinazolinones substituted with phenoxyphenylacetic acid derivatives |
| US5374638A (en) | 1993-03-19 | 1994-12-20 | Merck & Co., Inc. | Six membered ring fused imidazoles substituted with phenoxyphenylacetic acid derivatives used to treat asthma |
| AU711936B2 (en) * | 1996-08-09 | 1999-10-28 | Banyu Pharmaceutical Co., Ltd. | Stereoselective deoxygenation reaction |
| WO1998033781A1 (en) | 1997-01-30 | 1998-08-06 | Bristol-Myers Squibb Company | Method for preventing or treating low renin hypertension by administering an endothelin antagonist |
-
1997
- 1997-08-05 AT AT97936396T patent/ATE251611T1/de not_active IP Right Cessation
- 1997-08-05 AU AU39075/97A patent/AU732213B2/en not_active Ceased
- 1997-08-05 WO PCT/US1997/013725 patent/WO1998006698A1/en not_active Ceased
- 1997-08-05 CA CA002262837A patent/CA2262837C/en not_active Expired - Fee Related
- 1997-08-05 EP EP97936396A patent/EP0923556B1/de not_active Expired - Lifetime
- 1997-08-05 DE DE69725455T patent/DE69725455T2/de not_active Expired - Fee Related
- 1997-08-05 ES ES97936396T patent/ES2207747T3/es not_active Expired - Lifetime
- 1997-08-05 JP JP50981498A patent/JP3262805B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0923556B1 (de) | 2003-10-08 |
| EP0923556A4 (de) | 1999-12-15 |
| AU3907597A (en) | 1998-03-06 |
| WO1998006698A1 (en) | 1998-02-19 |
| DE69725455D1 (de) | 2003-11-13 |
| CA2262837A1 (en) | 1998-02-19 |
| EP0923556A1 (de) | 1999-06-23 |
| JP3262805B2 (ja) | 2002-03-04 |
| CA2262837C (en) | 2003-03-11 |
| DE69725455T2 (de) | 2004-08-12 |
| AU732213B2 (en) | 2001-04-12 |
| JP2000507957A (ja) | 2000-06-27 |
| ES2207747T3 (es) | 2004-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |