ATE251616T1 - Verfahren zur herstellung von 5- hydroxymethylthiazole - Google Patents
Verfahren zur herstellung von 5- hydroxymethylthiazoleInfo
- Publication number
- ATE251616T1 ATE251616T1 AT98942099T AT98942099T ATE251616T1 AT E251616 T1 ATE251616 T1 AT E251616T1 AT 98942099 T AT98942099 T AT 98942099T AT 98942099 T AT98942099 T AT 98942099T AT E251616 T1 ATE251616 T1 AT E251616T1
- Authority
- AT
- Austria
- Prior art keywords
- hydroxymethylthiazole
- compound
- formula
- preparation
- producing
- Prior art date
Links
- WKBQQWDVVHGWDB-UHFFFAOYSA-N 1,3-thiazol-5-ylmethanol Chemical compound OCC1=CN=CS1 WKBQQWDVVHGWDB-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- -1 hydroxymethylthiazole compound Chemical class 0.000 abstract 2
- JNHDLNXNYPLBMJ-UHFFFAOYSA-N 1,3-thiazol-2-ylmethanol Chemical compound OCC1=NC=CS1 JNHDLNXNYPLBMJ-UHFFFAOYSA-N 0.000 abstract 1
- 229940126214 compound 3 Drugs 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910000029 sodium carbonate Inorganic materials 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/921,399 US5959118A (en) | 1997-08-29 | 1997-08-29 | Process for the preparation of 5-hydroxymethylthiazoles |
| PCT/US1998/017100 WO1999011636A1 (en) | 1997-08-29 | 1998-08-18 | Process for the preparation of 5-hydroxymethylthiazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE251616T1 true ATE251616T1 (de) | 2003-10-15 |
Family
ID=25445373
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98942099T ATE251616T1 (de) | 1997-08-29 | 1998-08-18 | Verfahren zur herstellung von 5- hydroxymethylthiazole |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5959118A (de) |
| EP (1) | EP1007517B1 (de) |
| JP (1) | JP2002510331A (de) |
| AT (1) | ATE251616T1 (de) |
| CA (1) | CA2294089A1 (de) |
| DE (1) | DE69818837T2 (de) |
| DK (1) | DK1007517T3 (de) |
| ES (1) | ES2209198T3 (de) |
| PT (1) | PT1007517E (de) |
| WO (1) | WO1999011636A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1313624B1 (it) | 1999-09-21 | 2002-09-09 | Archimica Spa Ora Clariant Lif | Procedimento per la sintesi del ritonavir |
| CN101863853B (zh) * | 2009-12-28 | 2012-12-19 | 安徽贝克联合制药有限公司 | 一锅煮法制备5-羟甲基噻唑工艺 |
| BR112020008124A2 (pt) | 2017-10-27 | 2020-10-06 | Syngenta Participations Ag | composições de controle de vetores, métodos e produtos utilizando as mesmas |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3299083A (en) * | 1967-01-17 | Processes for preparing hydroxy- methylthiazole | ||
| US2332906A (en) * | 1939-10-03 | 1943-10-26 | Foldi Zolten | Process for preparation of sulphonamide derivatives |
| DE3631538A1 (de) * | 1986-09-17 | 1988-03-24 | Bayer Ag | Verfahren zur herstellung von 2-chlor-5-chlormethylthiazol |
| US5539122A (en) * | 1989-05-23 | 1996-07-23 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| US5354866A (en) * | 1989-05-23 | 1994-10-11 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| JPH10509177A (ja) * | 1994-11-22 | 1998-09-08 | アボツト・ラボラトリーズ | ５−ヒドロキシメチルチアゾールの製造方法 |
| DE19520612A1 (de) * | 1995-06-06 | 1996-12-12 | Bayer Ag | Verfahren zur Herstellung von Benzylalkohol |
| WO1997010226A1 (en) * | 1995-09-11 | 1997-03-20 | Novartis Ag | Process for preparing a 2-chloro-5-chloromethyl-thiazole compound |
| GB9518824D0 (en) * | 1995-09-14 | 1995-11-15 | Fine Organics Ltd | Preparation of substituted thiazoles |
| DE19547076A1 (de) * | 1995-12-18 | 1997-06-19 | Bayer Ag | Verbessertes Verfahren zur Herstellung von 5-Hydroxymethylthiazol |
| ES2224187T3 (es) * | 1995-12-21 | 2005-03-01 | Syngenta Participations Ag | Procedimiento para la preparacion de 2-cloro-5-clorometiltiazol. |
| KR100520249B1 (ko) * | 1997-01-22 | 2005-10-12 | 신젠타 파티서페이션즈 아게 | 티아졸 유도체의 제조 방법 |
| US5773625A (en) * | 1997-10-02 | 1998-06-30 | Abbott Laboratories | Process for the preparation of disubstituted carbonates |
-
1997
- 1997-08-29 US US08/921,399 patent/US5959118A/en not_active Expired - Lifetime
-
1998
- 1998-08-18 WO PCT/US1998/017100 patent/WO1999011636A1/en not_active Ceased
- 1998-08-18 AT AT98942099T patent/ATE251616T1/de not_active IP Right Cessation
- 1998-08-18 ES ES98942099T patent/ES2209198T3/es not_active Expired - Lifetime
- 1998-08-18 DK DK98942099T patent/DK1007517T3/da active
- 1998-08-18 DE DE69818837T patent/DE69818837T2/de not_active Expired - Fee Related
- 1998-08-18 JP JP51684099A patent/JP2002510331A/ja not_active Ceased
- 1998-08-18 CA CA002294089A patent/CA2294089A1/en not_active Abandoned
- 1998-08-18 EP EP98942099A patent/EP1007517B1/de not_active Expired - Lifetime
- 1998-08-18 PT PT98942099T patent/PT1007517E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2209198T3 (es) | 2004-06-16 |
| DE69818837T2 (de) | 2004-07-22 |
| CA2294089A1 (en) | 1999-03-11 |
| DK1007517T3 (da) | 2004-02-09 |
| EP1007517B1 (de) | 2003-10-08 |
| DE69818837D1 (de) | 2003-11-13 |
| WO1999011636A1 (en) | 1999-03-11 |
| PT1007517E (pt) | 2004-03-31 |
| EP1007517A1 (de) | 2000-06-14 |
| US5959118A (en) | 1999-09-28 |
| JP2002510331A (ja) | 2002-04-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1007517 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |