ATE252158T1 - Nicht-nukleotid verknüpfende reagentien - Google Patents

Nicht-nukleotid verknüpfende reagentien

Info

Publication number
ATE252158T1
ATE252158T1 AT97926780T AT97926780T ATE252158T1 AT E252158 T1 ATE252158 T1 AT E252158T1 AT 97926780 T AT97926780 T AT 97926780T AT 97926780 T AT97926780 T AT 97926780T AT E252158 T1 ATE252158 T1 AT E252158T1
Authority
AT
Austria
Prior art keywords
pct
reagents
nucleotide
linking reagents
nucleotide linking
Prior art date
Application number
AT97926780T
Other languages
English (en)
Inventor
Su George Sheng-Hui
Rajkumar Siva Iyer
Sunil K Aggarwal
Krishan L Kalra
Original Assignee
Biogenex Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogenex Lab filed Critical Biogenex Lab
Application granted granted Critical
Publication of ATE252158T1 publication Critical patent/ATE252158T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2416—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of cycloaliphatic alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT97926780T 1996-05-15 1997-05-15 Nicht-nukleotid verknüpfende reagentien ATE252158T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64782096A 1996-05-15 1996-05-15
PCT/US1997/009094 WO1997043451A1 (en) 1996-05-15 1997-05-15 Non-nucleotide linking reagents

Publications (1)

Publication Number Publication Date
ATE252158T1 true ATE252158T1 (de) 2003-11-15

Family

ID=24598396

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97926780T ATE252158T1 (de) 1996-05-15 1997-05-15 Nicht-nukleotid verknüpfende reagentien

Country Status (8)

Country Link
US (1) US6130323A (de)
EP (1) EP0954606B1 (de)
JP (1) JP2001509784A (de)
AT (1) ATE252158T1 (de)
AU (1) AU733647B2 (de)
CA (1) CA2253969A1 (de)
DE (1) DE69725611T2 (de)
WO (1) WO1997043451A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4004230B2 (ja) * 1998-11-06 2007-11-07 株式会社三菱化学ヤトロン 架橋アビジン含有新規複合体、架橋アビジンを用いる分析方法、並びに分析用試薬及びキット
EP1307592B1 (de) 2000-08-11 2006-07-05 University of Utah Research Foundation Einfach markierte oligonukleotidsonden
US7560231B2 (en) 2002-12-20 2009-07-14 Roche Molecular Systems, Inc. Mannitol and glucitol derivatives
WO2004089295A2 (en) * 2003-04-01 2004-10-21 Chromagen, Inc. Homogeneous and heterogeneous assay methods using nucleation centers and novel covalent chemistries for the rapid measurement of phosphorylation and de-phosphorylation
CA2463719A1 (en) 2003-04-05 2004-10-05 F. Hoffmann-La Roche Ag Nucleotide analogs with six membered rings
EP1502958A1 (de) * 2003-08-01 2005-02-02 Roche Diagnostics GmbH Neues Format zur Detektion von Heissstart- und Echtzeit-Polymerasekettenreaktion
EP1700922B1 (de) 2005-03-10 2016-08-24 Roche Diagnostics GmbH 3-Substituierte 5-Nitroindolderivate und diese enthaltende markierte Oligonukleotidsonden
DE502005008153D1 (de) 2005-11-23 2009-10-29 Roche Diagnostics Gmbh Polynukleotid mit Phosphatmimetikum
JP4713514B2 (ja) * 2006-02-20 2011-06-29 エフ．ホフマン−ラ ロシュ アーゲー 改善された標識試薬
ES2374686T3 (es) 2007-05-14 2012-02-21 Historx, Inc. Separación en compartimentos por caracterización de píxel usando agrupamiento de datos de imágenes.
EP2162728B1 (de) 2007-06-15 2016-07-27 Novartis AG Mikroskopisches system und verfahren zur erfassung von standardisierten daten
CA2604317C (en) 2007-08-06 2017-02-28 Historx, Inc. Methods and system for validating sample images for quantitative immunoassays
CA2596204C (en) 2007-08-07 2019-02-26 Historx, Inc. Method and system for determining an optimal dilution of a reagent
WO2009029810A1 (en) 2007-08-31 2009-03-05 Historx, Inc. Automatic exposure time selection for imaging tissue
AU2009293380B2 (en) 2008-09-16 2016-05-19 Novartis Ag Reproducible quantification of biomarker expression
WO2011034605A2 (en) 2009-09-16 2011-03-24 Genentech, Inc. Coiled coil and/or tether containing protein complexes and uses thereof
AR080793A1 (es) 2010-03-26 2012-05-09 Roche Glycart Ag Anticuerpos biespecificos
JP5766296B2 (ja) 2010-12-23 2015-08-19 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ポリペプチド−ポリヌクレオチド複合体、およびエフェクター成分の標的化された送達におけるその使用
CN103384825B (zh) 2010-12-23 2017-05-24 霍夫曼-拉罗奇有限公司 通过二价结合剂检测经翻译后修饰的多肽
MX2014009565A (es) 2012-02-10 2014-11-10 Genentech Inc Anticuerpos monocatenarios y otros heteromultimeros.
RU2015100656A (ru) 2012-06-27 2016-08-20 Ф. Хоффманн-Ля Рош Аг Способ получения конъюгатов fc-фрагмента антитела, включающих по меньшей мере одну связывающую группировку, которая специфически связывается с мишенью, и их применения
JP6203838B2 (ja) 2012-06-27 2017-09-27 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 少なくとも２つの異なる結合実体を含む、テーラーメイドの高度に選択的かつ多重特異的なターゲティング実体を選択および作製するための方法、ならびにその使用
WO2016087416A1 (en) 2014-12-03 2016-06-09 F. Hoffmann-La Roche Ag Multispecific antibodies
WO2018013999A1 (en) 2016-07-15 2018-01-18 Am Chemicals Llc Non-nucleosidic solid supports and phosphoramidite building blocks for oligonucleotide synthesis
CN108219513B (zh) * 2018-03-14 2019-11-08 青岛科技大学 一种羧基荧光素的制备方法

Also Published As

Publication number Publication date
EP0954606A1 (de) 1999-11-10
EP0954606B1 (de) 2003-10-15
DE69725611T2 (de) 2004-07-29
JP2001509784A (ja) 2001-07-24
US6130323A (en) 2000-10-10
DE69725611D1 (de) 2003-11-20
AU733647B2 (en) 2001-05-17
AU3146597A (en) 1997-12-05
CA2253969A1 (en) 1997-11-20
WO1997043451A1 (en) 1997-11-20
EP0954606A4 (de) 1999-12-22

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