ATE253079T1 - Methoden zur aufreinigung von authentischem igf aus hefewirtszellen - Google Patents

Methoden zur aufreinigung von authentischem igf aus hefewirtszellen

Info

Publication number
ATE253079T1
ATE253079T1 AT96919305T AT96919305T ATE253079T1 AT E253079 T1 ATE253079 T1 AT E253079T1 AT 96919305 T AT96919305 T AT 96919305T AT 96919305 T AT96919305 T AT 96919305T AT E253079 T1 ATE253079 T1 AT E253079T1
Authority
AT
Austria
Prior art keywords
methods
host cells
yeast host
purifying
authentic igf
Prior art date
Application number
AT96919305T
Other languages
English (en)
Inventor
Cynthia Cowgill
Luis Juarbe
Patricio Riquelme
Glenn Dorin
Christopher M Bussineau
Robert D Kudrna
Asuman G Otzurk
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/477,984 external-priority patent/US7193042B1/en
Application filed by Chiron Corp filed Critical Chiron Corp
Application granted granted Critical
Publication of ATE253079T1 publication Critical patent/ATE253079T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
AT96919305T 1995-06-07 1996-06-07 Methoden zur aufreinigung von authentischem igf aus hefewirtszellen ATE253079T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/477,984 US7193042B1 (en) 1995-06-07 1995-06-07 Methods for purifying authentic IGF from yeast hosts
US66348196A 1996-06-06 1996-06-06
PCT/US1996/009828 WO1996040776A1 (en) 1995-06-07 1996-06-07 Methods for purifying authentic igf from yeast hosts

Publications (1)

Publication Number Publication Date
ATE253079T1 true ATE253079T1 (de) 2003-11-15

Family

ID=27045743

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96919305T ATE253079T1 (de) 1995-06-07 1996-06-07 Methoden zur aufreinigung von authentischem igf aus hefewirtszellen

Country Status (7)

Country Link
US (1) US6117983A (de)
EP (1) EP0832121B1 (de)
JP (3) JP2002514890A (de)
AT (1) ATE253079T1 (de)
AU (1) AU6167596A (de)
DE (1) DE69630524T2 (de)
WO (1) WO1996040776A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7071313B1 (en) * 1995-06-07 2006-07-04 Cephalon, Inc. Methods of purifying authentic IGF from yeast hosts
US7193042B1 (en) * 1995-06-07 2007-03-20 Chiron Corporation Methods for purifying authentic IGF from yeast hosts
JP2001512684A (ja) 1997-08-05 2001-08-28 カイロン コーポレイション 新規のｐｉｃｈｉａｐａｓｔｏｒｉｓ遺伝子配列およびそれらの使用方法
US7067485B2 (en) 1997-11-07 2006-06-27 Chiron Corporation IGF-I composition and its use
DK1084136T3 (da) 1998-06-01 2005-01-03 Genentech Inc Adskillelse af monomere af et antistof fra dets multimere ved anvendelse af ionbytterchromatografi
US6605450B1 (en) 2000-05-25 2003-08-12 Chiron Corporation Iron regulation of the PpSEC10 transcriptional regulatory region of Pichia pastoris and methods of use
AU2001280436A1 (en) * 2000-07-12 2002-01-21 Eli Lilly And Company Process to increase protein stability
AU2003901507A0 (en) * 2003-03-28 2003-04-17 Norika Holdings Process for isolating a pharmaceutical product
EP1988154B1 (de) * 2007-04-30 2013-08-21 Ajinomoto Co., Inc. Verfahren zur Herstellung des humanen insulinähnlichen Wachstumsfaktors I
US9447163B2 (en) 2011-02-01 2016-09-20 Novo Nordisk A/S Purification of insulin
CN113556943A (zh) 2018-12-31 2021-10-26 奥姆尼根研究有限责任公司 饲料补充剂
CA3186604A1 (en) 2020-06-12 2021-12-16 Phibro Animal Health Corporation Composition or combination comprising anionic dietary supplement and 25-hydroxy vitamin d
WO2023192262A1 (en) 2022-04-01 2023-10-05 Phibro Animal Health Corporation A combination comprising bacillus and an essential oil and methods for making and using

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992004363A1 (en) * 1990-09-04 1992-03-19 The Salk Institute Biotechnology/Industrial Associates, Inc. Production of insulin-like growth factor-1 in methylotrophic yeast cells
US5231178A (en) * 1991-01-16 1993-07-27 The Salk Institute Biotechnology/Industrial Associates, Inc. Method for the purification of intact, correctly-folded insulin-like growth factor-1
US5288931A (en) * 1991-12-06 1994-02-22 Genentech, Inc. Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
AU3812993A (en) * 1992-03-24 1993-10-21 Synergen, Inc. Refolding and purification of insulin-like growth factor I
US5407810A (en) * 1993-08-20 1995-04-18 Genentech, Inc. Aqueous multiple-phase isolation of polypeptide
US5663304A (en) * 1993-08-20 1997-09-02 Genentech, Inc. Refolding of misfolded insulin-like growth factor-I
US5451660A (en) * 1993-12-13 1995-09-19 Genentech, Inc. Method for purifying polypeptides
US5446024A (en) * 1993-12-17 1995-08-29 Genentech, Inc. Purification of insulin-like growth factor
EP0779927A1 (de) * 1994-09-08 1997-06-25 Chiron Corporation Methode zur gesteigerten herstellung von insulin-ähnlichem wachstumsfaktor
US5650496A (en) * 1995-04-14 1997-07-22 Cephalon, Inc. IGF-I purification process

Also Published As

Publication number Publication date
JP2005253475A (ja) 2005-09-22
DE69630524D1 (de) 2003-12-11
US6117983A (en) 2000-09-12
JP2002514890A (ja) 2002-05-21
AU6167596A (en) 1996-12-30
WO1996040776A1 (en) 1996-12-19
DE69630524T2 (de) 2004-08-05
EP0832121B1 (de) 2003-10-29
JP2008054693A (ja) 2008-03-13
EP0832121A1 (de) 1998-04-01

Similar Documents

Publication Publication Date Title
ATE253079T1 (de) Methoden zur aufreinigung von authentischem igf aus hefewirtszellen
AU2002360331A1 (en) Egviii endoglucanase and nucleic acids encoding the same
NZ521396A (en) Fusion proteins comprising two or more Neisseria polypeptides
KR970707599A (ko) 유기 연료 셀, 및 그 작동방법과 그를 위한 전극 제조방법(Organic fuel cell, and methods of operation theeof and manufacture of electrode therefor)
WO2003052057A3 (en) Egvi endoglucanase and nucleic acids encoding the same
WO1996022308A3 (en) Appetite suppression factor and related methods
WO2004034493A3 (en) Fuel cell assembly and method of making the same
WO2003052118A3 (en) Bgl4 beta-glucosidase and nucleic acids encoding the same
ATE412002T1 (de) Gruppen zum einfangen von nukleinsäuren
AU1172099A (en) Biometric system and techniques suitable therefor
WO2003052054A3 (en) Bgl5 beta-glucosidase and nucleic acids encoding the same
AU2433901A (en) Chimeric natriuretic peptides
DK0894126T3 (da) Alkalisk phosphatase-deficient trådformet svamp
DE69711632D1 (de) Methode zur dissoziation von biotin komplexen
EP0783527A4 (de) Cathepsin-02-protease
DK0770139T3 (da) En svamp, hvor areA-genet er blevet modificeret, samt et areA-gen fra aspergillus oryzae
WO1999008695A8 (en) FLUORESCENT AMYLOID Aβ PEPTIDES AND USES THEREOF
NO910982D0 (no) Uratoksydase-aktivt protein, rekombinant gen som koder for det, ekspresjonsvektor, mikroorganismer og transformerteceller.
WO1999025843A3 (en) Human checkpoint kinase, hcds1, compositions and methods
WO1996027665A3 (en) Neuron-restrictive silencer factor proteins
ATE254176T1 (de) Erhöhte produktion von beta-galaktosidase in aspergillus oryzae
EP0751222A3 (de) Für Endoglycoceramidase kodierendes Gen
IT1284637B1 (it) Cella elettrolitica impiegante un elettrodo a diffusione di gas.
AU2002246091A1 (en) Electrolyte membrane, membrane electrode units comprising the same, method for the production thereof and specific uses therefor
WO2004024904A3 (en) Infectious hepacivirus pseudo-particles containing functional e1, e2 envelope proteins

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties