DK0894126T3 - Alkalisk phosphatase-deficient trådformet svamp - Google Patents

Alkalisk phosphatase-deficient trådformet svamp

Info

Publication number
DK0894126T3
DK0894126T3 DK97914177T DK97914177T DK0894126T3 DK 0894126 T3 DK0894126 T3 DK 0894126T3 DK 97914177 T DK97914177 T DK 97914177T DK 97914177 T DK97914177 T DK 97914177T DK 0894126 T3 DK0894126 T3 DK 0894126T3
Authority
DK
Denmark
Prior art keywords
filamentous fungus
alkaline phosphatase
fungi
production
methods
Prior art date
Application number
DK97914177T
Other languages
English (en)
Inventor
Jan Lehmbeck
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of DK0894126T3 publication Critical patent/DK0894126T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungi isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Mushroom Cultivation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Detergent Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK97914177T 1996-03-27 1997-03-26 Alkalisk phosphatase-deficient trådformet svamp DK0894126T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK35496 1996-03-27
DK55596 1996-05-09
EP97914177A EP0894126B1 (en) 1996-03-27 1997-03-26 Alkaline protease deficient filamentous fungi

Publications (1)

Publication Number Publication Date
DK0894126T3 true DK0894126T3 (da) 2006-06-12

Family

ID=26063843

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97914177T DK0894126T3 (da) 1996-03-27 1997-03-26 Alkalisk phosphatase-deficient trådformet svamp

Country Status (10)

Country Link
US (1) US6291209B1 (da)
EP (1) EP0894126B1 (da)
JP (1) JP4263241B2 (da)
CN (1) CN1120235C (da)
AT (1) ATE317005T1 (da)
AU (1) AU2152897A (da)
DE (1) DE69735199T2 (da)
DK (1) DK0894126T3 (da)
ES (1) ES2257774T3 (da)
WO (1) WO1997035956A1 (da)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE313620T1 (de) 1996-09-19 2006-01-15 Novozymes As Wirtszellen und methoden für die produktion von proteinen
WO2003066847A2 (en) 2002-02-08 2003-08-14 Novozymes A/S Phytase variants
US6806062B1 (en) 1998-10-05 2004-10-19 Novozymes A/S Fungal transcriptional activator useful in methods for producing polypeptides
DE69934596T2 (de) * 1998-10-05 2007-10-04 Novozymes A/S Transkriptionsaktivator prtt aus dem pilz aspergillus niger verwendbar in verfahren zur herstellung von polypeptiden
EP2302044A1 (en) 1998-11-27 2011-03-30 Novozymes A/S Lipolytic enzyme variants
AR029759A1 (es) 1999-07-09 2003-07-16 Novozymes As Variante de glucoamilasa original, una construccion de adn, un vector de expresion recombinante, una celula, un proceso para convertir almidon, uso de una variante de glucoamilasa para un proceso de fermentacion y metodo para mejorar la estabilidad termica.
WO2001034784A1 (en) 1999-11-10 2001-05-17 Novozymes A/S Fungamyl-like alpha-amylase variants
CN102174535B (zh) 2000-03-14 2014-04-09 诺维信公司 在制备多肽的方法中有效的真菌转录激活因子
AU2001267333A1 (en) 2000-06-26 2002-01-08 Novozymes A/S Lipolytic enzyme
EP1840211A1 (en) 2001-10-31 2007-10-03 Danisco A/S Pyranosone dehydratase from phanerochaete chrysosporium
DE60310264T2 (de) 2002-12-17 2007-07-05 Novozymes A/S Thermostabile alpha-amylase
CN101103118B (zh) 2005-01-10 2012-04-18 诺维信公司 使用两种脂解酶的混合物从甘油三酯和醇产生脂肪酸烷基酯的方法
DK2410048T3 (da) 2005-01-24 2016-11-28 Dsm Ip Assets Bv Fremgangsmåde til fremstilling af en forbindelse af interesse i en filamentøs svampecelle
EP1861421B1 (en) 2005-03-16 2011-10-19 Novozymes Adenium Biotech A/S Recombinant expression of insect defensins in Aspergillus
DK1941025T3 (da) 2005-10-17 2011-09-26 Novozymes As Brug af svampemutanter til ekspression af antistoffer
US20080280328A1 (en) 2005-11-18 2008-11-13 Novozymes A/S Glucoamylase Variants
CA2657975A1 (en) 2006-06-29 2008-01-03 Dsm Ip Assets B.V. A method for achieving improved polypeptide expression
EP2851424B1 (en) 2007-03-09 2016-09-21 Novozymes A/S Thermostable asparaginases
US8383391B2 (en) 2007-10-01 2013-02-26 Novozymes A/S Mutant cell with deleted or disrupted genes encoding protease
WO2009133464A2 (en) 2008-04-30 2009-11-05 Danisco A/S Oxidation process
JP5305353B2 (ja) * 2009-06-23 2013-10-02 ヤマサ醤油株式会社 ａｌｐＢをコードする遺伝子の機能が欠損している麹菌及びその利用
GB201011513D0 (en) 2010-07-08 2010-08-25 Danisco Method
CN103443268A (zh) 2011-01-20 2013-12-11 诺维信公司 植物过氧化物酶在丝状真菌中的表达
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
US20140212885A1 (en) * 2011-09-22 2014-07-31 Danisco Us Inc. Endogenous dnase activity to reduce dna content
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
BR112014016587A2 (pt) 2012-01-05 2020-10-27 Novartis Ag células fúngicas filamentosas deficientes de protease e métodos de uso das mesmas
DK2852610T3 (da) 2012-05-23 2018-09-03 Glykos Finland Oy Produktion af fucosylerede glycoproteiner
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
WO2015004241A2 (en) 2013-07-10 2015-01-15 Novartis Ag Multiple proteases deficient filamentous fungal cells and methods of use thereof
JP6368968B2 (ja) * 2014-01-22 2018-08-08 本田技研工業株式会社 形質転換体の製造方法、糖化酵素の生産方法、及び草木類バイオマスの糖化処理方法
AU2015293949B2 (en) 2014-07-21 2019-07-25 Teknologian Tutkimuskeskus Vtt Oy Production of glycoproteins with mammalian-like N-glycans in filamentous fungi
CN107105707B (zh) 2014-10-24 2022-07-22 杜邦营养生物科学有限公司 脯氨酸耐受性三肽基肽酶及其用途
EP3172329A1 (en) 2014-10-24 2017-05-31 Danisco US Inc. Method for producing alcohol by use of a tripeptidyl peptidase
JP6360787B2 (ja) * 2014-12-04 2018-07-18 本田技研工業株式会社 麹菌変異株及び形質転換体
PE20171138A1 (es) 2014-12-23 2017-08-09 4D Pharma Res Ltd Modulacion inmunitaria
DK3193901T3 (da) 2014-12-23 2018-05-28 4D Pharma Res Ltd Pirinpolypeptid og immunmodulation
CN106190874B (zh) * 2015-05-06 2020-06-26 中国科学院天津工业生物技术研究所 一种强化丝状真菌蛋白质生产的方法
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
LT3360559T (lt) 2015-06-15 2019-12-27 4D Pharma Research Limited Kompozicijos, apimančios bakterijų kamienus
EP3662917A1 (en) 2015-06-15 2020-06-10 4D Pharma Research Limited Compositions comprising bacterial strains
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
PE20180243A1 (es) 2015-06-15 2018-01-31 4D Pharma Res Ltd Composiciones que comprenden cepas bacterianas
EP3064589A1 (en) 2015-07-29 2016-09-07 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Enzymatic process for the preparation of testosterone and esters thereof
MA41013A (fr) 2015-11-20 2017-08-30 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
MX2018009216A (es) 2016-02-25 2018-11-09 Dupont Nutrition Biosci Aps Metodo para producir un hidrolizado de proteina empleando una tripeptidil peptidasa de aspergillus fumigatus.
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
MX373290B (es) 2016-03-04 2020-06-18 4D Pharma Plc Composiciones que comprenden cepas bacterianas.
TWI802545B (zh) 2016-07-13 2023-05-21 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
MA48940A (fr) 2017-05-22 2020-04-08 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
MA41708A (fr) 2017-05-24 2020-04-08 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
JP2020523326A (ja) 2017-06-14 2020-08-06 フォーディー ファーマ リサーチ リミテッド４Ｄ Ｐｈａｒｍａ Ｒｅｓｅａｒｃｈ Ｌｉｍｉｔｅｄ 細菌株を含む組成物
PL3638271T3 (pl) 2017-06-14 2021-03-22 4D Pharma Research Limited Kompozycje zawierające szczepy bakteryjne
TWI767013B (zh) 2017-06-14 2022-06-11 英商4D製藥研究有限公司 包含細菌品系之組成物
JP7234932B2 (ja) 2017-10-10 2023-03-08 味の素株式会社 タンパク質の製造法
US20230313121A1 (en) * 2020-05-14 2023-10-05 Dyadic International (Usa), Inc. Modified filamentous fungi for production of exogenous proteins
CN115836127B (zh) 2020-06-11 2026-03-13 味之素株式会社 蛋白的制造方法
CN112725399B (zh) * 2020-12-29 2023-04-11 海南云皓生物科技有限公司 一种香菇寡肽的制备方法及用途
CN118765328A (zh) 2022-04-29 2024-10-11 诺维信公司 脂肪酸烷基酯的产生

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1333777C (en) * 1988-07-01 1995-01-03 Randy M. Berka Aspartic proteinase deficient filamentous fungi
DK0414297T3 (da) * 1989-08-11 1997-07-07 Genencor Int Effektiv fremstilling af mutantproteaser
AU661844B2 (en) * 1991-04-01 1995-08-10 Merck Sharp & Dohme Corp. Genes which influence (pichia) proteolytic activity, and uses therefor
DK0574347T3 (da) * 1992-04-15 2004-01-26 Novartis Ag Hidtil ukendt svampeprotease

Also Published As

Publication number Publication date
EP0894126B1 (en) 2006-02-01
DE69735199T2 (de) 2006-09-21
CN1120235C (zh) 2003-09-03
ES2257774T3 (es) 2006-08-01
CN1214731A (zh) 1999-04-21
ATE317005T1 (de) 2006-02-15
DE69735199D1 (de) 2006-04-13
US6291209B1 (en) 2001-09-18
WO1997035956A1 (en) 1997-10-02
JP4263241B2 (ja) 2009-05-13
AU2152897A (en) 1997-10-17
EP0894126A1 (en) 1999-02-03
JP2000507106A (ja) 2000-06-13

Similar Documents

Publication Publication Date Title
ATE317005T1 (de) Alkaline-phosphatase-defiziente, filamentöse pilze
EA200100419A1 (ru) Трансформационная система в области грибов гифомицетов-хозяев
DE69739996D1 (de) Methoden und Zusammensetzungen zur Herstellung von Polypeptiden
ATE317441T1 (de) Cathepsin-02-protease
LV10309A (lv) Panemiens rekombinanto olbaltumvielu fermentativai skelsanai ar IgA proteazem savienota olbaltumviela rekombinanta DNS suna
ATE454393T1 (de) Egvii-endoglucanase und dafür codierende nukleinsäuren
FI953705A0 (fi) Parannettu proteiinien laskostamismenetelmä
DE69826465D1 (de) Verfahren zur in vitro evolution von proteinfunktionen
HUP0301659A2 (hu) Kukorica cellulóz-szintetázok és alkalmazásuk
ATE342359T1 (de) Design von beta-faltblatt-proteinen mit spezifischen bindungseigenschaften
ATE367439T1 (de) Expressionsklonierung in filamentösen pilzen
ATE313620T1 (de) Wirtszellen und methoden für die produktion von proteinen
DK1204738T3 (da) Fremgangsmåde til nedsættelse af skumdannelsen under dyrkning af en mikroorganisme
DK1117798T3 (da) Fungal transskriptionel aktivator egnet ved fremgangsmåder til produktion af polypeptider
ATE457352T1 (de) Subtilisin-carlsberg-proteine mit verminderter immunogenität
ATE360695T1 (de) Cortistatin: neuropeptide, zusammensetzungen und methoden
DE60122562D1 (de) Nukleinsäuren, die für stichodactylidae chromoproteine kodieren
ATE315638T1 (de) Oxalacetat-hydrolase defiziente fungale wirtszellen
NO931368L (no) Sopp-protease
HK1044956A1 (zh) 重組細胞聚變份子
ATE374825T1 (de) Verwendung von caspasen zur herstellung von reifen rekombinanten fusionsproteinen
DE69634757D1 (de) Vektor zur expression von n-terminal verlängerten proteinen in hefezellen
PT1379639E (pt) A glucuranilo epimerase c5 o dna que a codifica e as suas utilizacoes
IL104003A0 (en) Recombinant vaccines and method of producing same
DE69202858D1 (de) Herstellungsverfahren für chymosin.