ATE253123T1 - Ein intaktes fpv-tk-gen enthaltender rekombinanter virus der vogelpocken - Google Patents

Ein intaktes fpv-tk-gen enthaltender rekombinanter virus der vogelpocken

Info

Publication number
ATE253123T1
ATE253123T1 AT91114300T AT91114300T ATE253123T1 AT E253123 T1 ATE253123 T1 AT E253123T1 AT 91114300 T AT91114300 T AT 91114300T AT 91114300 T AT91114300 T AT 91114300T AT E253123 T1 ATE253123 T1 AT E253123T1
Authority
AT
Austria
Prior art keywords
fpv
gene
intact
recombinant
intergenic region
Prior art date
Application number
AT91114300T
Other languages
English (en)
Inventor
Friedrich Prof Dr Dorner
Friedrich Scheiflinger
Falko Guenter Dr Falkner
Original Assignee
Baxter Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Healthcare Sa filed Critical Baxter Healthcare Sa
Application granted granted Critical
Publication of ATE253123T1 publication Critical patent/ATE253123T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT91114300T 1991-08-26 1991-08-26 Ein intaktes fpv-tk-gen enthaltender rekombinanter virus der vogelpocken ATE253123T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91114300A EP0538496B1 (de) 1991-08-26 1991-08-26 Ein intaktes FPV-tk-Gen enthaltender rekombinanter Virus der Vogelpocken

Publications (1)

Publication Number Publication Date
ATE253123T1 true ATE253123T1 (de) 2003-11-15

Family

ID=8207076

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91114300T ATE253123T1 (de) 1991-08-26 1991-08-26 Ein intaktes fpv-tk-gen enthaltender rekombinanter virus der vogelpocken

Country Status (12)

Country Link
US (1) US5670367A (de)
EP (2) EP1380651A2 (de)
JP (1) JP2703853B2 (de)
AT (1) ATE253123T1 (de)
AU (1) AU661488B2 (de)
CA (1) CA2076903A1 (de)
CZ (1) CZ264092A3 (de)
DE (1) DE69133333T2 (de)
DK (1) DK0538496T3 (de)
ES (1) ES2212795T3 (de)
HU (1) HUT62653A (de)
SK (1) SK264092A3 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955652A (en) * 1992-06-16 1999-09-21 The Trustees Of The University Of Pennsylvania Plant genes for sensitivity to ethylene and pathogens
US5925358A (en) * 1993-02-26 1999-07-20 Syntro Corporation Recombinant fowlpox viruses and uses thereof
US6136318A (en) * 1993-02-26 2000-10-24 Cochran; Mark D. Recombinant fowlpox viruses and uses thereof
EP0696204A4 (de) * 1993-02-26 1999-03-31 Syntro Corp Rekombinierter geflügelpockenvirus und seine verwendung
US5821059A (en) * 1993-08-06 1998-10-13 Iowa State University Research Foundation, Inc. Mycoplasma expression system
ES2243937T3 (es) * 1994-04-29 2005-12-01 Baxter Healthcare S.A. Poxvirus recombinados en regiones esenciales con la ayuda de polinucleotidos extraños.
EP0753581A1 (de) 1995-07-10 1997-01-15 Immuno Ag Verbesserte rekombinante eukaryotische zytoplasmatische Viren, Methode ihrer Herstellung und ihrer Verwendung als Impfstoffe
US6534631B1 (en) 1998-07-15 2003-03-18 Human Genome Sciences, Inc. Secreted protein HT5GJ57
AU6518298A (en) * 1997-03-28 1998-10-22 Nippon Zeon Co., Ltd. Novel dna vector and vaccines containing novel recombinant dna vectors as the active ingredient
US7091315B1 (en) 1998-07-15 2006-08-15 Human Genome Sciences, Inc. Protein HDPBQ71
US20070014787A1 (en) 1998-07-15 2007-01-18 Human Genome Sciences, Inc. 71 human secreted proteins
EP1097199A4 (de) * 1998-07-15 2005-02-23 Human Genome Sciences Inc 71 humane sekretierte proteine
US6872811B1 (en) * 1998-09-30 2005-03-29 Millennium Pharmaceuticals, Inc. HRPCa9 and HRPCa10 nucleic acids and polypeptides
US8623379B2 (en) 2000-03-02 2014-01-07 Emory University Compositions and methods for generating an immune response
US20020106798A1 (en) 2000-03-02 2002-08-08 Robinson Harriet L. DNA expression vectors and methods of use
ATE419338T1 (de) * 2000-03-24 2009-01-15 Cell Genesys Inc Menschliche zellspezifische urotheliale regulatorische sequenzen der transkription des uroplakins, dessen vektoren und verwendungsverfahren
GB0014288D0 (en) * 2000-06-10 2000-08-02 Smithkline Beecham Biolog Vaccine
WO2002010190A2 (en) * 2000-07-29 2002-02-07 Genaissance Pharmaceuticals, Inc. Haplotypes of the il12b gene
NZ524116A (en) * 2000-09-04 2005-08-26 House Foods Corp Isozymes of lacrimator component synthase and gene encoding the same
WO2002094867A2 (fr) * 2001-02-07 2002-11-28 Institut Pasteur Sequence du genome de photorhabdus luminescens souche tto1 et utilisations
CN100446812C (zh) * 2001-03-08 2008-12-31 美国国有健康与人类服务部 表达修饰的hiv包膜、gag和pol基因的mva
JP2005517381A (ja) * 2001-06-12 2005-06-16 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Ｗｉｔ３．０、軟組織創傷治癒を制御する新規遺伝子
UA82479C2 (uk) * 2002-05-16 2008-04-25 Бавариан Нордика А/С Міжгенні регіони як сайти вставки в геном модифікованого вірусу коров'ячої віспи ankara (mva)
US7056733B2 (en) * 2003-02-19 2006-06-06 University Of Kentucky Research Foundation Nucleic acids encoding Sarcocystis neurona antigen and uses thereof
JP5052893B2 (ja) * 2003-02-20 2012-10-17 アメリカ合衆国 ポックスベクターにおける新規の挿入部位
GB0326798D0 (en) 2003-11-17 2003-12-24 Crusade Lab Ltd Methods for generating mutant virus
JP2007511216A (ja) 2003-11-17 2007-05-10 クルセイド ラボラトリーズ リミテッド 変異ウイルス
US7897146B2 (en) 2003-11-17 2011-03-01 Crusade Laboratories Limited Treatment using herpes simplex virus
JP4271122B2 (ja) * 2004-10-15 2009-06-03 財団法人 ひろしま産業振興機構 カイコでの組換えタンパク質製造のためのポリヌクレオチド
US20060090646A1 (en) * 2004-11-04 2006-05-04 Questair Technologies Inc. Adsorbent material for selective adsorption of carbon monoxide and unsaturated hydrocarbons
US7807180B2 (en) 2007-08-21 2010-10-05 University Of Massachusetts Poxvirus methods and compositions
US8314228B2 (en) * 2009-02-13 2012-11-20 Aurora Algae, Inc. Bidirectional promoters in Nannochloropsis
EP2482825B1 (de) 2009-10-02 2016-11-23 The Trustees of Columbia University in the City of New York Diagnostische fisch-reoviren-zusammensetzungen
ES2606511T3 (es) 2011-04-06 2017-03-24 Biovaxim Limited Composiciones farmacéuticas para prevenir y/o tratar una enfermedad por VIH en seres humanos
EP2855699B1 (de) * 2012-06-01 2018-07-18 ExxonMobil Research and Engineering Company Promotoren und terminatoren zur verwendung in eukaryotischen zellen
US10612034B2 (en) 2012-06-01 2020-04-07 Exxonmobil Research And Engineering Company Promoters and terminators for use in eukaryotic cells
CA2893692C (en) * 2012-12-04 2019-06-25 Exxonmobil Research And Engineering Company Tetraselmis promoters and terminators for use in eukaryotic cells
DK3329016T3 (da) * 2015-07-31 2022-01-10 Bavarian Nordic As Promotorer til forbedring af ekspression i poxvirus
CN109071592B (zh) 2016-01-08 2022-07-19 吉奥瓦科斯公司 用于产生对肿瘤相关抗原的免疫应答的组合物和方法
US11311612B2 (en) 2017-09-19 2022-04-26 Geovax, Inc. Compositions and methods for generating an immune response to treat or prevent malaria
CA3167052A1 (en) 2020-02-14 2021-08-19 Mary Jo Hauser Vaccines and uses thereof to induce an immune response to sars-cov2

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5174993A (en) * 1981-12-24 1992-12-29 Health Research Inc. Recombinant avipox virus and immunological use thereof
US5338683A (en) * 1981-12-24 1994-08-16 Health Research Incorporated Vaccinia virus containing DNA sequences encoding herpesvirus glycoproteins
DE3576360D1 (de) * 1984-05-22 1990-04-12 Transgene Sa Expressionsvektoren fuer faktor ix und aktionsfaktor ix produzierende zellinien.
US5032520A (en) * 1985-03-29 1991-07-16 National Research Development Corporation DNA sequences encoding infectious bronchitis virus spike protein
US4713004A (en) * 1986-09-04 1987-12-15 Vent Plant Corporation Submergible screw-type dental implant and method of utilization
WO1988002022A1 (en) * 1986-09-22 1988-03-24 Commonwealth Scientific And Industrial Research Or Recombinant poxviruses
DE3853088T2 (de) * 1987-03-27 1995-10-19 Nippon Zeon Co Rekombinantes Avipoxvirus.
DE10399032I1 (de) * 1987-08-28 2004-01-29 Health Research Inc Rekombinante Viren.
CA1340203C (en) * 1987-09-16 1998-12-15 Noboru Yanagida Recombinant apivoxvirus
FR2632863B2 (fr) * 1987-10-29 1990-08-31 Transgene Sa Virus du fowlpox recombinant et vaccins derives de ces virus
DE3813093A1 (de) * 1988-04-19 1989-11-09 Immuno Ag Rekombinantes plasmid, verfahren zum herstellen eines rekombinanten avipoxvirus, rekombinantes avipoxvirus und dessen verwendung
US5310671A (en) * 1988-06-24 1994-05-10 British Technology Group Limited Fowlpox virus non-essential regions
US5093258A (en) * 1988-08-26 1992-03-03 Therion Biologics Corporation Recombinant fowlpox virus and recombination vector
CA2001001A1 (en) * 1988-10-21 1990-04-21 Matthew M. Binns Fowlpox virus promoter

Also Published As

Publication number Publication date
JPH05192165A (ja) 1993-08-03
DK0538496T3 (da) 2004-02-23
EP0538496A1 (de) 1993-04-28
ES2212795T3 (es) 2004-08-01
JP2703853B2 (ja) 1998-01-26
AU1958092A (en) 1993-03-04
EP1380651A2 (de) 2004-01-14
CZ264092A3 (en) 1993-03-17
HU9202753D0 (en) 1993-05-28
DE69133333T2 (de) 2004-07-29
SK264092A3 (en) 1995-07-11
DE69133333D1 (de) 2003-12-04
US5670367A (en) 1997-09-23
HUT62653A (en) 1993-05-28
EP0538496B1 (de) 2003-10-29
AU661488B2 (en) 1995-07-27
CA2076903A1 (en) 1993-02-27

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