ATE253589T1 - Bmp-5-derivate - Google Patents

Bmp-5-derivate

Info

Publication number: ATE253589T1
Authority: AT; Austria
Prior art keywords: bmp; derivatives; protein; bone; proteins
Prior art date: 1990-09-26

Application number

AT91917761T

Other languages

English (en)

Inventor

John M Wozney

Vicki A Rosen

Elizabeth A Wang

Anthony J Celeste

Original Assignee

Inst Genetics Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-09-26

Filing date

1991-09-26

Publication date

2003-11-15

1991-09-26 Application filed by Inst Genetics Llc filed Critical Inst Genetics Llc

2003-11-15 Application granted granted Critical

2003-11-15 Publication of ATE253589T1 publication Critical patent/ATE253589T1/de

Links

108010049976 Bone Morphogenetic Protein 5 Proteins 0.000 title abstract 2
102000008152 Bone Morphogenetic Protein 5 Human genes 0.000 title abstract 2
101000899388 Homo sapiens Bone morphogenetic protein 5 Proteins 0.000 abstract 1
210000000988 bone and bone Anatomy 0.000 abstract 1
210000000845 cartilage Anatomy 0.000 abstract 1
230000007547 defect Effects 0.000 abstract 1
102000046096 human BMP5 Human genes 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
230000017423 tissue regeneration Effects 0.000 abstract 1
230000029663 wound healing Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/108—Plasmid DNA episomal vectors
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Biochemistry (AREA)
Wood Science & Technology (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physics & Mathematics (AREA)
Toxicology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Plant Pathology (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Gastroenterology & Hepatology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT91917761T 1990-09-26 1991-09-26 Bmp-5-derivate ATE253589T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US58822790A	1990-09-26	1990-09-26
PCT/US1991/007069 WO1992005199A1 (en)	1990-09-26	1991-09-26	Bmp-5 derivatives

Publications (1)

Publication Number	Publication Date
ATE253589T1 true ATE253589T1 (de)	2003-11-15

Family

ID=24353000

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91917761T ATE253589T1 (de)	1990-09-26	1991-09-26	Bmp-5-derivate

Country Status (4)

Country	Link
EP (1)	EP0550625B1 (de)
AT (1)	ATE253589T1 (de)
DE (1)	DE69133338T2 (de)
WO (1)	WO1992005199A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6150328A (en)	1986-07-01	2000-11-21	Genetics Institute, Inc.	BMP products
US6919308B2 (en)	1988-04-08	2005-07-19	Stryker Corporation	Osteogenic devices
US6586388B2 (en)	1988-04-08	2003-07-01	Stryker Corporation	Method of using recombinant osteogenic protein to repair bone or cartilage defects
US5266683A (en) *	1988-04-08	1993-11-30	Stryker Corporation	Osteogenic proteins
US5284756A (en) *	1988-10-11	1994-02-08	Lynn Grinna	Heterodimeric osteogenic factor
US5674844A (en) *	1991-03-11	1997-10-07	Creative Biomolecules, Inc.	Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
US5229495A (en) *	1991-06-18	1993-07-20	Ludwig Institute For Cancer Research	Substantially pure receptor like TGF-β 1 binding molecules and uses thereof
DK0698094T3 (da) *	1993-05-12	2004-05-03	Inst Genetics Llc	BMP-11-sammensætninger
US6291206B1 (en)	1993-09-17	2001-09-18	Genetics Institute, Inc.	BMP receptor proteins
DE69434651T2 (de)	1993-12-07	2007-03-08	Genetics Institute, Inc., Cambridge	Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen
US5962427A (en) *	1994-02-18	1999-10-05	The Regent Of The University Of Michigan	In vivo gene transfer methods for wound healing
US5942496A (en) *	1994-02-18	1999-08-24	The Regent Of The University Of Michigan	Methods and compositions for multiple gene transfer into bone cells
DE69723429T3 (de)	1996-03-22	2007-09-20	Curis, Inc., Cambridge	Verfahren zur verbesserten funktionellen Erholung der motorischen Koordination, der Sprache oder Sinneswahrnehmung nach Trauma oder Ischämie des ZNS
US6492508B1 (en)	1996-06-03	2002-12-10	United States Surgical Corp. A Division Of Tyco Healthcare Group	Nucleic acids encoding extracellular matrix proteins
US6727224B1 (en)	1999-02-01	2004-04-27	Genetics Institute, Llc.	Methods and compositions for healing and repair of articular cartilage
ATE271886T1 (de)	1999-10-15	2004-08-15	Inst Genetics Llc	Hyaluronsäure enthaltende zusammensetzungen zur abgabe osteogener proteine
TWI329129B (en)	2001-02-08	2010-08-21	Wyeth Corp	Modified and stabilized gdf propeptides and uses thereof
WO2002099037A2 (en)	2001-06-01	2002-12-12	Wyeth	Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
TWI267378B (en) *	2001-06-08	2006-12-01	Wyeth Corp	Calcium phosphate delivery vehicles for osteoinductive proteins
EP1885751B1 (de)	2005-05-27	2011-11-16	BBS - Bioactive Bone Substitutes Oy	Heparin-Bindungsstelle enthaltendes Knochenmorphogenetisches Protein 6 und osteogene Vorrichtungen und pharmazeutische Produkte, die diese enthalten

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4789732A (en) *	1980-08-04	1988-12-06	Regents Of The University Of California	Bone morphogenetic protein composition
US4795804A (en) *	1983-08-16	1989-01-03	The Regents Of The University Of California	Bone morphogenetic agents
IL83003A (en) *	1986-07-01	1995-07-31	Genetics Inst	Osteoinductive factors
KR900700617A (ko) *	1988-04-08	1990-08-16	브루스 엠. 에이센	뼈 및 연골 유도 조성물
ES2113857T3 (es) *	1989-03-28	1998-05-16	Genetics Inst	Composiciones osteoinductoras.

1991
- 1991-09-26 DE DE69133338T patent/DE69133338T2/de not_active Expired - Lifetime
- 1991-09-26 AT AT91917761T patent/ATE253589T1/de not_active IP Right Cessation
- 1991-09-26 EP EP91917761A patent/EP0550625B1/de not_active Expired - Lifetime
- 1991-09-26 WO PCT/US1991/007069 patent/WO1992005199A1/en not_active Ceased

Also Published As

Publication number	Publication date
EP0550625B1 (de)	2003-11-05
DE69133338T2 (de)	2004-04-15
EP0550625A1 (de)	1993-07-14
DE69133338D1 (de)	2003-12-11
WO1992005199A1 (en)	1992-04-02

Legal Events

Date

Code

Title

Description

2004-06-15

UEP

Publication of translation of european patent specification

Ref document number: 0550625

Country of ref document: EP

2011-06-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DK0536186T3 (da)	2002-05-21	Knogle- og brusk-dannelsesfremkaldende proteiner
DK0429570T3 (da)	1998-04-27	Osteoinducerende præparater
DE69133338D1 (de)	2003-12-11	Bmp-5-derivate
DE69528058D1 (de)	2002-10-10	Bmp-9 zusammensetzungen
CA2108770A1 (en)	1992-12-26	Bmp-9 compositions
ATE265529T1 (de)	2004-05-15	Bmp-10 zusammensetzungen
DE69028535D1 (de)	1996-10-17	Herstellung des vaskulären endothelialen zellwachstumsfaktors
EP0693928A4 (de)	1998-06-03	Aminozucker- und glykosaminoglykanzusammensetzung zur behandlung und reparatus von bindegewebe
ATE177954T1 (de)	1999-04-15	Verfahren zur behandlung von knochengeweben und implantierbare biomaterialien dafür
FI963696L (fi)	1996-11-07	Geeli ihosairauksien hoitoon ja ihon desinfiointiin
ATE298800T1 (de)	2005-07-15	Verfahren und desoxyribonukleinsäure zur herstellung von gewebefaktor-protein
ATE349428T1 (de)	2007-01-15	Prostaglandinagoniste und deren verwendung zur behandlung von knochenerkrankungen
ES2088006T3 (es)	1996-08-01	Composiciones farmaceuticas osteoinductivas.
DE69233022D1 (de)	2003-05-28	Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
DE69432832D1 (de)	2003-07-24	Vorrichtung und verfahren zur photoaktivierung
DK53497A (da)	1997-05-09	Osteoinduktive præparater
DE3788231D1 (de)	1993-12-23	Kosmetisches mittel und zusammensetzung zur behandlung der haut.
DE69114653D1 (de)	1995-12-21	Sterilisierendes Gemisch und Verfahren zur Sterilisation.
NO931413L (no)	1993-04-16	Fremgangsmaater og preparater for behandling av celleproliferasjonssykdommer
ES2044170T3 (es)	1994-01-01	Sal de estroncio, su procedimiento de preparacion y las composiciones farmaceuticas que la contienen.
DE59410340D1 (de)	2004-01-15	Verwendung von Bradykinin-Antagonisten zur Behandlung von Viruserkrankungen
DE69431103D1 (de)	2002-09-05	Injizierbares implantat zur behandlungen von falten und hautdepressionen
DE69433055D1 (de)	2003-09-25	Zusammensetzung zum heilen von verletztem gewebe, verfahren für ihre herstellung und ihre verwendung