|
DE20004692U1
(de)
|
2000-03-14 |
2001-07-26 |
Sofamor Danek GmbH, 94469 Deggendorf |
Wirbelimplantat zum Einschrauben in einen Wirbelzwischenraum
|
|
US6150328A
(en)
|
1986-07-01 |
2000-11-21 |
Genetics Institute, Inc. |
BMP products
|
|
DK0698094T3
(da)
*
|
1993-05-12 |
2004-05-03 |
Inst Genetics Llc |
BMP-11-sammensætninger
|
|
US6291206B1
(en)
|
1993-09-17 |
2001-09-18 |
Genetics Institute, Inc. |
BMP receptor proteins
|
|
DE69434651T2
(de)
|
1993-12-07 |
2007-03-08 |
Genetics Institute, Inc., Cambridge |
Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen
|
|
US5906827A
(en)
*
|
1994-06-03 |
1999-05-25 |
Creative Biomolecules, Inc. |
Matrix for the manufacture of autogenous replacement body parts
|
|
US5846770A
(en)
*
|
1994-11-22 |
1998-12-08 |
Genetics Institute, Inc. |
DNA molecules encoding human chordin
|
|
US5782919A
(en)
|
1995-03-27 |
1998-07-21 |
Sdgi Holdings, Inc. |
Interbody fusion device and method for restoration of normal spinal anatomy
|
|
US5645084A
(en)
*
|
1995-06-07 |
1997-07-08 |
Danek Medical, Inc. |
Method for spinal fusion without decortication
|
|
US6206922B1
(en)
|
1995-03-27 |
2001-03-27 |
Sdgi Holdings, Inc. |
Methods and instruments for interbody fusion
|
|
US5635372A
(en)
*
|
1995-05-18 |
1997-06-03 |
Genetics Institute, Inc. |
BMP-15 compositions
|
|
DE69629294T2
(de)
|
1995-06-05 |
2004-04-29 |
Genetics Institute, LLC, Cambridge |
Verwendung von knochenmorphogeneseproteinen zur heilung und reparatur von bindegewebebefestigung
|
|
US5902785A
(en)
*
|
1995-06-06 |
1999-05-11 |
Genetics Institute, Inc. |
Cartilage induction by bone morphogenetic proteins
|
|
US6423095B1
(en)
|
1995-10-16 |
2002-07-23 |
Sdgi Holdings, Inc. |
Intervertebral spacers
|
|
US5989289A
(en)
|
1995-10-16 |
1999-11-23 |
Sdgi Holdings, Inc. |
Bone grafts
|
|
US5700774A
(en)
*
|
1996-03-26 |
1997-12-23 |
Genetics Institute, Inc. |
Compositions comprising bone morphogenic proteins and truncated parathyroid hormone related peptide, and methods of inducing cartilage by administration of same
|
|
US5965403A
(en)
*
|
1996-09-18 |
1999-10-12 |
Genetics Institute, Inc. |
Nucleic acids encoding bone morphogenic protein-16 (BMP-16)
|
|
AU732421B2
(en)
|
1996-10-23 |
2001-04-26 |
Warsaw Orthopedic, Inc. |
Spinal spacer
|
|
US6037519A
(en)
*
|
1997-10-20 |
2000-03-14 |
Sdgi Holdings, Inc. |
Ceramic fusion implants and compositions
|
|
EP1350525A3
(de)
|
1997-02-07 |
2003-12-10 |
Stryker Corporation |
Matrixlose osteogene Vorrichtungen und Implantate und Verfahren zu deren Verwendung
|
|
US20010016646A1
(en)
|
1998-03-20 |
2001-08-23 |
David C. Rueger |
Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects
|
|
US7041641B2
(en)
|
1997-03-20 |
2006-05-09 |
Stryker Corporation |
Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
|
|
TW562807B
(en)
*
|
1997-04-01 |
2003-11-21 |
Chugai Pharmaceutical Co Ltd |
Novel secretory membrane protein
|
|
CA2291514C
(en)
|
1997-05-30 |
2011-07-12 |
Mariel Therapeutics, Inc. |
Methods for evaluating tissue morphogenesis and activity
|
|
US5972368A
(en)
|
1997-06-11 |
1999-10-26 |
Sdgi Holdings, Inc. |
Bone graft composites and spacers
|
|
US20020052026A1
(en)
|
1997-10-08 |
2002-05-02 |
Steven M. Vicik |
Methods of refolding proteins
|
|
US6511509B1
(en)
|
1997-10-20 |
2003-01-28 |
Lifenet |
Textured bone allograft, method of making and using same
|
|
AU1906599A
(en)
*
|
1997-12-09 |
1999-06-28 |
Ontogeny, Inc. |
Pancreatic-derived factors, and uses related thereto
|
|
US6027917A
(en)
|
1997-12-10 |
2000-02-22 |
Genetics Institute, Inc. |
Bone morphogenetic protein (BMP)-17 and BMP-18 compositions
|
|
US7147839B2
(en)
|
1998-05-29 |
2006-12-12 |
Curis, Inc. |
Methods for evaluating tissue morphogenesis and activity
|
|
JP4156197B2
(ja)
|
1998-08-06 |
2008-09-24 |
ウォーソー・オーソペディック・インコーポレーテッド |
複合型椎骨間スペーサ
|
|
US6727224B1
(en)
|
1999-02-01 |
2004-04-27 |
Genetics Institute, Llc. |
Methods and compositions for healing and repair of articular cartilage
|
|
ATE271886T1
(de)
|
1999-10-15 |
2004-08-15 |
Inst Genetics Llc |
Hyaluronsäure enthaltende zusammensetzungen zur abgabe osteogener proteine
|
|
US6752831B2
(en)
|
2000-12-08 |
2004-06-22 |
Osteotech, Inc. |
Biocompatible osteogenic band for repair of spinal disorders
|
|
US8758438B2
(en)
|
2000-12-08 |
2014-06-24 |
Warsaw Orthopedic, Inc. |
Implant for orthopedic applications
|
|
WO2002099037A2
(en)
|
2001-06-01 |
2002-12-12 |
Wyeth |
Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
|
|
TWI267378B
(en)
|
2001-06-08 |
2006-12-01 |
Wyeth Corp |
Calcium phosphate delivery vehicles for osteoinductive proteins
|
|
WO2003046188A1
(en)
*
|
2001-11-27 |
2003-06-05 |
Nexyte Ab |
Production of eukaryotic proteins and nucleic acid molecules in c. elegans
|
|
CH695985A5
(de)
*
|
2002-01-21 |
2006-11-15 |
Straumann Holding Ag |
Oberflächenmodifizierte Implantate.
|
|
AU2003221582A1
(en)
|
2002-05-03 |
2003-11-17 |
Millenium Biologix Inc. |
Connective tissue stimulating peptides
|
|
DE602004005477T2
(de)
|
2003-09-12 |
2007-12-13 |
Wyeth |
Injizierbare feste Calciumphosphat-Stäbe zur Abgabe von osteogenen Proteinen
|
|
PL1737734T3
(pl)
|
2004-03-10 |
2011-02-28 |
Scil Tech Gmbh |
Powlekane implanty, ich wytwarzanie i zastosowanie
|
|
JP2007530055A
(ja)
|
2004-03-26 |
2007-11-01 |
アクセルロン ファーマ インコーポレーテッド |
Bmp−3プロペプチドおよび関連する方法
|
|
WO2005116052A2
(en)
|
2004-04-27 |
2005-12-08 |
Research Development Foundation |
ANTAGONISM OF TGF-β SUPERFAMILY RECEPTOR SIGNALING
|
|
WO2005113590A2
(en)
|
2004-05-12 |
2005-12-01 |
Acceleron Pharma Inc. |
Bmp10 propeptides and related methods
|
|
ES2369629T3
(es)
|
2004-05-25 |
2011-12-02 |
Stryker Corporation |
Uso de op-1 para tratar defectos del cartílago.
|
|
US7749268B2
(en)
|
2004-05-26 |
2010-07-06 |
Warsaw Orthopedic, Inc. |
Methods for treating the spine
|
|
EP1771557B1
(de)
|
2004-06-24 |
2014-12-31 |
Acceleron Pharma Inc. |
GDF3-Propeptide und damit zusammenhängende Verfahren
|
|
EP3489257A1
(de)
|
2004-07-23 |
2019-05-29 |
Acceleron Pharma Inc. |
Actrii-rezeptor-polypeptide, verfahren und zusammensetzungen
|
|
US7473678B2
(en)
|
2004-10-14 |
2009-01-06 |
Biomimetic Therapeutics, Inc. |
Platelet-derived growth factor compositions and methods of use thereof
|
|
US8128933B2
(en)
|
2005-11-23 |
2012-03-06 |
Acceleron Pharma, Inc. |
Method of promoting bone growth by an anti-activin B antibody
|
|
EP2781222B1
(de)
|
2005-11-23 |
2017-08-02 |
Acceleron Pharma, Inc. |
Activin-actriia antagonisten zur verwendung in der förderung von knochenwachstum
|
|
US8147860B2
(en)
|
2005-12-06 |
2012-04-03 |
Etex Corporation |
Porous calcium phosphate bone material
|
|
EP1991282B1
(de)
|
2006-02-09 |
2013-06-19 |
BioMimetic Therapeutics, LLC |
Zusammensetzungen und verfahren zur behandlung von knochen
|
|
AU2007257208B2
(en)
|
2006-05-17 |
2013-05-02 |
Stryker Corporation |
Use of a soluble morphogenic protein complex for treating cartilage defects
|
|
CA2656278C
(en)
|
2006-06-30 |
2016-02-09 |
Biomimetic Therapeutics, Inc. |
Compositions and methods for treating rotator cuff injuries
|
|
US9161967B2
(en)
|
2006-06-30 |
2015-10-20 |
Biomimetic Therapeutics, Llc |
Compositions and methods for treating the vertebral column
|
|
AU2007234612B2
(en)
|
2006-12-14 |
2013-06-27 |
Johnson & Johnson Regenerative Therapeutics, Llc |
Protein stabilization formulations
|
|
US8895016B2
(en)
|
2006-12-18 |
2014-11-25 |
Acceleron Pharma, Inc. |
Antagonists of activin-actriia and uses for increasing red blood cell levels
|
|
US20100184659A1
(en)
|
2006-12-21 |
2010-07-22 |
Warren Jaworowicz |
Sustained-Release Formulations Comprising Crystals, Macromolecular Gels, and Particulate Suspensions of Biologic Agents
|
|
CA2677007A1
(en)
|
2007-02-01 |
2008-08-07 |
Acceleron Pharma Inc. |
Activin-actriia antagonists and uses for treating or preventing breast cancer
|
|
TW201803890A
(zh)
|
2007-02-02 |
2018-02-01 |
艾瑟勒朗法瑪公司 |
衍生自ActRIIB的變體與其用途
|
|
EP2481415B1
(de)
|
2007-02-09 |
2019-09-11 |
Acceleron Pharma Inc. |
Zusammensetzungen enhaltend Activin-ActRIIA-Antagonisten
|
|
US7678764B2
(en)
|
2007-06-29 |
2010-03-16 |
Johnson & Johnson Regenerative Therapeutics, Llc |
Protein formulations for use at elevated temperatures
|
|
WO2009020744A1
(en)
|
2007-08-07 |
2009-02-12 |
Johnson & Johnson Regenerative Therapeutics, Llc |
Protein formulations comprising gdf-5 in aqueous acidic solution
|
|
JP2010539236A
(ja)
|
2007-09-18 |
2010-12-16 |
アクセルロン ファーマ, インコーポレイテッド |
アクチビン−ActRIIa拮抗薬およびFSH分泌を低減または阻害するための使用
|
|
AU2009214629A1
(en)
|
2008-02-13 |
2009-08-20 |
Eric T. Choi |
BMP-7 for use in treating vascular sclerosis
|
|
BRPI0911048A2
(pt)
|
2008-04-14 |
2015-12-29 |
Atrm Llc |
formulações líquidas tamponadas de gdf-5
|
|
TWI626945B
(zh)
|
2008-08-14 |
2018-06-21 |
艾瑟勒朗法瑪公司 |
使用gdf阱以增加紅血球水平
|
|
US8216997B2
(en)
|
2008-08-14 |
2012-07-10 |
Acceleron Pharma, Inc. |
Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
|
|
KR20110067035A
(ko)
|
2008-09-09 |
2011-06-20 |
바이오미메틱 세라퓨틱스, 인크. |
건 및 인대 손상의 치료를 위한 혈소판-유래 성장 인자 조성물 및 방법
|
|
AU2010204985A1
(en)
|
2009-01-13 |
2011-08-04 |
Acceleron Pharma Inc. |
Methods for increasing adiponectin
|
|
WO2010093925A2
(en)
|
2009-02-12 |
2010-08-19 |
Stryker Corporation |
PERIPHERAL ADMINISTRATION OF PROTEINS INCLUDING TGF-β SUPERFAMILY MEMBERS FOR TREATMENT OF SYSTEMIC DISORDERS AND DISEASE
|
|
US20100204124A1
(en)
|
2009-02-12 |
2010-08-12 |
Mary Elizabeth Pecquet Goad |
Compositions and Methods for Minimally-Invasive Systemic Delivery of Proteins Including TGF-Beta Superfamily Members
|
|
WO2010110974A1
(en)
|
2009-03-24 |
2010-09-30 |
Stryker Corporation |
Methods and compositions for tissue engineering
|
|
JP5912078B2
(ja)
|
2009-06-08 |
2016-04-27 |
アクセルロン ファーマ, インコーポレイテッド |
熱発生性脂肪細胞を増加させるための方法
|
|
WO2010144696A1
(en)
|
2009-06-11 |
2010-12-16 |
Burnham Institute For Medical Research |
Directed differentiation of stem cells
|
|
EP3290439B1
(de)
|
2009-06-12 |
2020-09-02 |
Acceleron Pharma Inc. |
Verkürzte actriib-fc-fusionsproteine
|
|
US9399086B2
(en)
|
2009-07-24 |
2016-07-26 |
Warsaw Orthopedic, Inc |
Implantable medical devices
|
|
WO2011031856A1
(en)
|
2009-09-09 |
2011-03-17 |
Stryker Corporation |
Bmp -7 for use in treating pain induced by injuries and diseases of an articular joint
|
|
US20110224410A1
(en)
|
2009-09-17 |
2011-09-15 |
Hile David |
Buffers for Controlling the pH of Bone Morphogenetic Proteins
|
|
EP3332796A1
(de)
|
2009-11-17 |
2018-06-13 |
Acceleron Pharma Inc. |
Actriib-proteine und varianten davon sowie verwendungen davon zur utrophin-induktion für therapien gegen muskuläre dystrophie
|
|
CA2785038A1
(en)
|
2009-12-22 |
2011-07-21 |
Stryker Corporation |
Bmp-7 variants with reduced immunogenicity
|
|
CN107080834A
(zh)
|
2010-02-22 |
2017-08-22 |
生物模拟治疗有限责任公司 |
用于治疗腱病的血小板衍生生长因子组合物和方法
|
|
WO2011139594A2
(en)
|
2010-04-27 |
2011-11-10 |
Medtronic, Inc. |
Artificial bursa for intra-articular drug delivery
|
|
KR20130132824A
(ko)
|
2010-11-08 |
2013-12-05 |
악셀레론 파마 인코포레이티드 |
Actriia 결합제 및 이의 용도
|
|
US9809636B2
(en)
|
2012-04-06 |
2017-11-07 |
Acceleron Pharma Inc. |
Methods for increasing red blood cell levels comprising administering BMP9
|
|
WO2014012101A1
(en)
|
2012-07-13 |
2014-01-16 |
Trustees Of Tufts College |
Silk powder compaction for production of constructs with high mechanical strength and stiffness
|
|
US10195249B2
(en)
|
2012-11-02 |
2019-02-05 |
Celgene Corporation |
Activin-ActRII antagonists and uses for treating bone and other disorders
|
|
AU2014253753B2
(en)
|
2013-04-19 |
2017-03-30 |
Arteriocyte Medical Systems, Inc. |
Demineralized bone fibers having controlled geometry and shapes and methods thereof
|
|
MA40008A
(fr)
|
2014-06-13 |
2021-05-05 |
Acceleron Pharma Inc |
Antagoniste actrii pour le traitement et la prevention d'un ulcere cutane chez un sujet ayant l'anemie
|
|
GB201412290D0
(en)
|
2014-07-10 |
2014-08-27 |
Cambridge Entpr Ltd |
Novel use
|
|
MA41052A
(fr)
|
2014-10-09 |
2017-08-15 |
Celgene Corp |
Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii
|
|
TWI730949B
(zh)
|
2014-12-03 |
2021-06-21 |
美商西建公司 |
活化素-actrii拮抗劑及治療貧血之用途
|
|
WO2016123583A1
(en)
|
2015-01-29 |
2016-08-04 |
Theracell, Inc. |
Demineralized bone fiber composition for use in minimally invasive surgery
|
|
CN107683130B
(zh)
|
2015-06-17 |
2022-03-04 |
华沙整形外科股份有限公司 |
包括氧固醇的植入物和使用方法
|
|
CN108430458B
(zh)
|
2015-10-26 |
2022-05-10 |
哈佛学院院长等 |
还原和氧化的多糖及其使用方法
|
|
US10688222B2
(en)
|
2016-11-21 |
2020-06-23 |
Warsaw Orthopedic, Inc. |
Lyophilized moldable implants containing an oxysterol
|
|
US10639157B2
(en)
|
2017-03-14 |
2020-05-05 |
Theracell, Inc. |
Demineralized bone fiber composition for use in minimally invasive surgery
|
|
US11464888B2
(en)
|
2017-06-12 |
2022-10-11 |
Warsaw Orthopedic, Inc. |
Moldable formulations containing an oxysterol in an acellular tissue matrix
|
|
WO2019033082A1
(en)
|
2017-08-11 |
2019-02-14 |
Theracell, Inc. |
DEMINERALIZED BONE FIBER COMPOSITION FOR INCREASED FASTENING
|
|
US11103618B2
(en)
|
2018-02-22 |
2021-08-31 |
Warsaw Orthopedic, Inc. |
Demineralized bone matrix having improved handling characteristics
|
|
JP7531772B2
(ja)
|
2019-02-09 |
2024-08-13 |
セラセル,エルエルシー |
骨修復における固定を増強するための脱灰骨線維インプラント構成物及び方法
|
|
US11498880B2
(en)
|
2019-07-26 |
2022-11-15 |
Warsaw Orthopedic, Inc. |
Calcium phosphate granules and methods of making them
|
|
CN113603792B
(zh)
*
|
2021-08-26 |
2023-06-30 |
深圳市人民医院 |
一种重组骨形态发生蛋白-2及其制备方法和应用
|