ATE254623T1 - Vitamin-d-vorlaüferverbindungen, verfahren und intermediären zu deren herstellung - Google Patents

Vitamin-d-vorlaüferverbindungen, verfahren und intermediären zu deren herstellung

Info

Publication number
ATE254623T1
ATE254623T1 AT00983224T AT00983224T ATE254623T1 AT E254623 T1 ATE254623 T1 AT E254623T1 AT 00983224 T AT00983224 T AT 00983224T AT 00983224 T AT00983224 T AT 00983224T AT E254623 T1 ATE254623 T1 AT E254623T1
Authority
AT
Austria
Prior art keywords
vitamin
intermediaries
production
methods
precursor compounds
Prior art date
Application number
AT00983224T
Other languages
English (en)
Inventor
Jean-Claude Pascal
Maurits Vandewalle
Philippe Maillos
Clercq Pierre De
Original Assignee
Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theramex filed Critical Theramex
Application granted granted Critical
Publication of ATE254623T1 publication Critical patent/ATE254623T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/78—Benzoic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/40—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing six carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cephalosporin Compounds (AREA)
AT00983224T 1999-12-08 2000-12-04 Vitamin-d-vorlaüferverbindungen, verfahren und intermediären zu deren herstellung ATE254623T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99403065A EP1106618A1 (de) 1999-12-08 1999-12-08 Vorläuferverbindungen für den A-Ring von Vitamin-D, Verfahren zur Herstellung und Zwischenprodukte dazu
US09/456,509 US6191292B1 (en) 1999-12-08 1999-12-08 Precursors of the A-ring of vitamin D and method and intermediates for the preparation thereof
PCT/EP2000/012225 WO2001042251A1 (en) 1999-12-08 2000-12-04 Vitamin d precursors, method and intermediates

Publications (1)

Publication Number Publication Date
ATE254623T1 true ATE254623T1 (de) 2003-12-15

Family

ID=26153704

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00983224T ATE254623T1 (de) 1999-12-08 2000-12-04 Vitamin-d-vorlaüferverbindungen, verfahren und intermediären zu deren herstellung

Country Status (23)

Country Link
US (1) US6191292B1 (de)
EP (2) EP1106618A1 (de)
CN (1) CN1210282C (de)
AT (1) ATE254623T1 (de)
AU (1) AU782089B2 (de)
BR (1) BRPI0016184B8 (de)
CA (1) CA2393617C (de)
CZ (1) CZ303421B6 (de)
DE (1) DE60006714T2 (de)
DK (1) DK1235832T3 (de)
EE (1) EE05326B1 (de)
ES (1) ES2210022T3 (de)
HU (1) HU229508B1 (de)
IL (1) IL150089A0 (de)
MX (1) MXPA01012904A (de)
NO (1) NO327848B1 (de)
NZ (1) NZ519391A (de)
PL (1) PL201691B1 (de)
PT (1) PT1235832E (de)
RU (1) RU2247710C2 (de)
TW (1) TWI290928B (de)
WO (1) WO2001042251A1 (de)
ZA (1) ZA200204594B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2360145T3 (da) 2010-01-26 2012-07-09 Hybrigenics Sa Hidtil ukendt fremgangsmåde til isomerisering af kondenserede bicykliske strukturer og fremstilling af D-vitaminanaloger, der omfatter disse
CN104010525B (zh) * 2011-12-21 2017-08-25 默克专利股份有限公司 环己醇衍生物作为抗菌抗微生物活性物质的用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU699200B2 (en) * 1993-07-09 1998-11-26 Roger Bouillon Novel structural analogues of vitamin D

Also Published As

Publication number Publication date
CN1210282C (zh) 2005-07-13
CN1425019A (zh) 2003-06-18
EP1106618A1 (de) 2001-06-13
TWI290928B (en) 2007-12-11
WO2001042251A1 (en) 2001-06-14
CA2393617C (en) 2010-03-23
NO20022690D0 (no) 2002-06-06
DE60006714T2 (de) 2004-12-02
HUP0204521A2 (en) 2003-05-28
PL201691B1 (pl) 2009-04-30
BR0016184A (pt) 2002-08-20
DE60006714D1 (de) 2003-12-24
CZ303421B6 (cs) 2012-09-05
NZ519391A (en) 2003-08-29
HU229508B1 (en) 2014-01-28
EP1235832A1 (de) 2002-09-04
BRPI0016184B8 (pt) 2021-05-25
ZA200204594B (en) 2003-10-29
RU2247710C2 (ru) 2005-03-10
US6191292B1 (en) 2001-02-20
CA2393617A1 (en) 2001-06-14
EP1235832B1 (de) 2003-11-19
AU782089B2 (en) 2005-06-30
HUP0204521A3 (en) 2005-03-29
EE05326B1 (et) 2010-08-16
ES2210022T3 (es) 2004-07-01
CZ20021977A3 (cs) 2002-10-16
PT1235832E (pt) 2004-04-30
BRPI0016184B1 (pt) 2015-07-14
PL356389A1 (en) 2004-06-28
EE200200294A (et) 2003-08-15
NO327848B1 (no) 2009-10-05
AU2005101A (en) 2001-06-18
NO20022690L (no) 2002-06-06
MXPA01012904A (es) 2002-11-07
DK1235832T3 (da) 2004-03-22
IL150089A0 (en) 2002-12-01

Similar Documents

Publication Publication Date Title
ATE242241T1 (de) Imidazopyridinderivate und verfahren zu ihrer herstellung
ATE246180T1 (de) Benzofuranon-derivate und verfahren zu ihrer herstellung
PT1246812E (pt) Metodo para a preparacao de citalopram
ATE457972T1 (de) Verfahren zur herstellung von 7-amino-syn-3,5- dihydroxyheptansäurederivaten und zwischenverbindungen diesesverfahrens und deren herestellung
ATE337304T1 (de) Neues verfahren zur herstellung einer chinolon- carbonsäure
DE60006714D1 (de) Vitamin-d-vorlaüferverbindungen, verfahren und intermediären zu deren herstellung
PT1317455E (pt) Processo para a preparacao de um composto de imidazopiridina substituido
ATE267832T1 (de) Substanz gm-95, verfahren zu ihrer herstellung und ihre verwendung
DE69810273D1 (de) Vitamin d 3? derivate und verfahren zur herstellung derselben
MXPA04003086A (es) Proceso para sintesis estereoselectiva de 2-hidroximetil-cromanos.
PT1165543E (pt) Processo para a preparacao de acido ¬s-(r*,s*)|-beta-¬¬¬1-¬1-oxo-3-(4-piperidinil)propil|-3-piperidinil|-carbonil|amino|-3-piridinopropanoico e derivados
GB0417063D0 (en) Process for the preparation of optically-active compounds
DE60233307D1 (de) Verfahren zur herstellung optisch aktiver propoxyanilinderivate
EP1258478A4 (de) Verfahren zur herstellung von chinoloncarbonsäuren und ihre zwischenprodukte
DE69511449D1 (de) Octahydro-2-Naphthalincarbonsäure-Derivate, ihre Herstellung und Verwendung
BR9910603A (pt) Método aprimorado paraa preparar derivados de norbenzomorfano valiosos farmaceuticamente
DE69815906D1 (de) Verfahren zur Herstellung von Chloroacetylaminothiazoleaceticsäure Derivate
ATE297478T1 (de) Verfahren zur herstellung von orthocarbonsäuretrialkylestern
ATE286539T1 (de) Verfahren zur herstellung von optisch aktiven 3,3,3- trifluormethyl- 2- alkylpropionsäurederivaten
IT1317886B1 (it) Procedimento per la preparazione di 9,10-diidro-pirrolo (2,1-b)(1,3)benzotiazepine 9-ammino sostituite.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1235832

Country of ref document: EP