ATE254665T1 - Elektrochemolumineszenz-test - Google Patents
Elektrochemolumineszenz-testInfo
- Publication number
- ATE254665T1 ATE254665T1 AT96903355T AT96903355T ATE254665T1 AT E254665 T1 ATE254665 T1 AT E254665T1 AT 96903355 T AT96903355 T AT 96903355T AT 96903355 T AT96903355 T AT 96903355T AT E254665 T1 ATE254665 T1 AT E254665T1
- Authority
- AT
- Austria
- Prior art keywords
- assay
- beta
- useful
- determining
- bacterial infection
- Prior art date
Links
- 238000003556 assay Methods 0.000 abstract 4
- 208000035143 Bacterial infection Diseases 0.000 abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 2
- 108020004256 Beta-lactamase Proteins 0.000 abstract 1
- 206010034133 Pathogen resistance Diseases 0.000 abstract 1
- 239000003782 beta lactam antibiotic agent Substances 0.000 abstract 1
- 102000006635 beta-lactamase Human genes 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 235000013372 meat Nutrition 0.000 abstract 1
- 239000008267 milk Substances 0.000 abstract 1
- 210000004080 milk Anatomy 0.000 abstract 1
- 235000013336 milk Nutrition 0.000 abstract 1
- 238000011002 quantification Methods 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 239000002132 β-lactam antibiotic Substances 0.000 abstract 1
- 229940124586 β-lactam antibiotics Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- G01N2333/986—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides (3.5.2), e.g. beta-lactamase (penicillinase, 3.5.2.6), creatinine amidohydrolase (creatininase, EC 3.5.2.10), N-methylhydantoinase (3.5.2.6)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2415/00—Assays, e.g. immunoassays or enzyme assays, involving penicillins or cephalosporins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Electroluminescent Light Sources (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/368,429 US5641623A (en) | 1995-01-04 | 1995-01-04 | Electrochemiluminescence assay |
| PCT/US1996/000120 WO1996021039A1 (en) | 1995-01-04 | 1996-01-04 | Electrochemiluminescence assay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE254665T1 true ATE254665T1 (de) | 2003-12-15 |
Family
ID=23451169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96903355T ATE254665T1 (de) | 1995-01-04 | 1996-01-04 | Elektrochemolumineszenz-test |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5641623A (de) |
| EP (1) | EP0801687B1 (de) |
| JP (1) | JP3122468B2 (de) |
| KR (1) | KR100444250B1 (de) |
| AT (1) | ATE254665T1 (de) |
| AU (1) | AU711795B2 (de) |
| CA (1) | CA2209546A1 (de) |
| DE (1) | DE69630775T2 (de) |
| WO (1) | WO1996021039A1 (de) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6316180B1 (en) * | 1995-01-04 | 2001-11-13 | Igen International, Inc. | Electrochemiluminescent monitoring of compounds/electrochemiluminescence assays |
| WO1996033411A1 (en) * | 1995-04-18 | 1996-10-24 | Igen, Inc. | Electrochemiluminescence of rare earth metal chelates |
| CA2223027A1 (en) * | 1995-06-07 | 1996-12-19 | Igen, Inc. | Electrochemiluminescent enzyme immunoassay |
| US6613583B1 (en) | 1997-06-27 | 2003-09-02 | Igen International, Inc. | Electrochemiluminescent label based on multimetallic assemblies |
| US6312896B1 (en) * | 1998-09-17 | 2001-11-06 | Igen Inaternational, Inc. | Assays for measuring nucleic acid binding proteins and enzyme activities |
| US7141436B2 (en) * | 1999-11-03 | 2006-11-28 | Science And Technology Corp. | Immunoassay and reagents and kits for performing the same |
| DK1412725T3 (en) | 2001-06-29 | 2019-03-25 | Meso Scale Technologies Llc | Multi-well plates for LUMINESCENSE TEST MEASUREMENTS |
| EP1412487B1 (de) | 2001-07-30 | 2010-06-16 | Meso Scale Technologies LLC | Assay-elektroden mit schichten aus immobilisiertem lipid/protein sowie verfahren zu deren herstellung und verwendung |
| AU2002341621A1 (en) | 2001-09-10 | 2003-03-24 | Meso Scale Technologies, Llc | Methods, reagents, kits and apparatus for protein function analysis |
| ES2324031T3 (es) * | 2002-10-29 | 2009-07-29 | Showa Yakuhin Kako Co., Ltd | Composicion de reactivos para discriminar beta-lactamasas, kit y metodo asociados. |
| EP1560930A4 (de) * | 2002-11-15 | 2007-05-16 | Applera Corp | NUKLEINSûURESEQUENZNACHWEIS |
| JP2008521007A (ja) * | 2004-11-17 | 2008-06-19 | バイオヴェリス コーポレイション | 電気化学発光測定法 |
| US20060275841A1 (en) * | 2004-12-20 | 2006-12-07 | Martin Blankfard | Assay method and apparatus with reduced sample matrix effects |
| WO2007002580A2 (en) * | 2005-06-23 | 2007-01-04 | Bioveris Corporation | Diagnostic as say system with multi -well reagent container |
| US20090317335A1 (en) * | 2006-04-20 | 2009-12-24 | Wenbin Lin | Hybrid Nanomaterials as Multimodal Imaging Contrast Agents |
| WO2009139939A2 (en) * | 2008-02-22 | 2009-11-19 | The University Of North Carolina At Chapel Hill | Hybrid nanoparticles as anti-cancer therapeutic agents and dual therapeutic/imaging contrast agents |
| PT2271938E (pt) | 2008-04-11 | 2014-05-09 | Univ Texas | Método e aparelho de amplificação de quimiluminescênci electrogerada por nanopartículas |
| US8802387B2 (en) * | 2008-04-30 | 2014-08-12 | Nanyang Technological University | Methods and compounds for detecting beta-lactamase activity |
| AU2009244904B2 (en) | 2008-05-08 | 2014-04-17 | Board Of Regents Of The University Of Texas System | Luminescent nanostructured materials for use in electrogenerated chemiluminescence |
| EP2370812A2 (de) * | 2008-12-08 | 2011-10-05 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Verfahren und kits zum direkten nachweis und zur erstellung eines suszeptibilitätsprofils beta-lactam-resistenter bakterien |
| US20100261292A1 (en) * | 2009-04-10 | 2010-10-14 | Meso Scale Technologies, Llc | Methods for Conducting Assays |
| EP2470914B1 (de) | 2009-07-27 | 2020-05-13 | Meso Scale Technologies, LLC | Assay-vorrichtungen und -verfahren |
| DE102010023452B4 (de) * | 2010-06-11 | 2012-11-08 | Bruker Daltonik Gmbh | Massenspektrometrische Messung von β-Lactamase-Resistenzen |
| CA2808485C (en) | 2010-08-19 | 2019-02-26 | Erasmus University Medical Center Rotterdam | Methods and means for characterizing antibiotic resistance in microorganisms |
| JP5943927B2 (ja) | 2010-10-14 | 2016-07-05 | メソ スケール テクノロジーズ エルエルシー | アッセイデバイスにおける試薬貯蔵 |
| BR112013007614B1 (pt) | 2010-10-25 | 2020-12-29 | F. Hoffmann-La Roche Ag | método para medir um analito, composição reagente, mistura reagente, uso de uma composição reagente, uso de uma amida de ácido carbônico e kit |
| WO2013009701A2 (en) | 2011-07-08 | 2013-01-17 | The University Of North Carolina At Chapel Hill | Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders |
| WO2013053953A1 (en) * | 2011-10-14 | 2013-04-18 | Université de Liège | Method for measuring beta-lactam antibiotics |
| EP2776833B1 (de) | 2011-11-11 | 2018-09-05 | Eli N. Glezer | Cobinder-unterstützte testverfahren |
| US9625465B2 (en) | 2012-05-15 | 2017-04-18 | Defined Diagnostics, Llc | Clinical diagnostic systems |
| US9075042B2 (en) | 2012-05-15 | 2015-07-07 | Wellstat Diagnostics, Llc | Diagnostic systems and cartridges |
| US9213043B2 (en) | 2012-05-15 | 2015-12-15 | Wellstat Diagnostics, Llc | Clinical diagnostic system including instrument and cartridge |
| CA3235305A1 (en) | 2013-01-04 | 2014-07-10 | Meso Scale Technologies, Llc. | Assay apparatuses, methods and reagents |
| DK2972353T3 (da) | 2013-03-11 | 2023-03-27 | Meso Scale Technologies Llc | Forbedrede fremgangsmåder til udførelse af multipleksanalyser |
| US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
| CA2904181A1 (en) | 2013-03-13 | 2014-10-09 | Anahit Aghvanyan | Sandwich immunoassay comprising anchoring reagent |
| US10202500B2 (en) | 2013-03-15 | 2019-02-12 | Lubrizol Advanced Materials, Inc. | Heavy metal free CPVC compounds |
| US10041953B2 (en) | 2013-04-04 | 2018-08-07 | Erasmus University Medical Center Rotterdam | Mass spectrometric determination of drug resistance |
| US10517822B2 (en) | 2013-11-06 | 2019-12-31 | The University Of Chicago | Nanoscale carriers for the delivery or co-delivery of chemotherapeutics, nucleic acids and photosensitizers |
| CA3229509A1 (en) | 2014-05-09 | 2015-11-12 | Meso Scale Technologies, Llc. | Graphene-modified electrodes |
| EP3143401A4 (de) | 2014-05-15 | 2017-10-11 | Meso Scale Technologies, LLC | Verbesserte testverfahren |
| CN110731961A (zh) | 2014-10-14 | 2020-01-31 | 芝加哥大学 | 金属有机框架、药物制剂及其在制备药物中的用途 |
| US10806694B2 (en) | 2014-10-14 | 2020-10-20 | The University Of Chicago | Nanoparticles for photodynamic therapy, X-ray induced photodynamic therapy, radiotherapy, radiodynamic therapy, chemotherapy, immunotherapy, and any combination thereof |
| KR102425339B1 (ko) | 2014-12-08 | 2022-07-25 | 에프. 호프만-라 로슈 아게 | 비타민 d 의 측정을 위한 방법 |
| FR3034523B1 (fr) * | 2015-04-03 | 2020-01-17 | Universite De Bourgogne | Nouvelle methode pour detecter la presence de bacteries productrices de beta-lactamases. |
| WO2017153574A1 (en) | 2016-03-11 | 2017-09-14 | Roche Diagnostics Gmbh | Branched-chain amines in electrochemiluminescence detection |
| EP3439666A4 (de) | 2016-05-20 | 2019-12-11 | The University of Chicago | Nanopartikel zur chemotherapie, gezielte therapie, photodynamische therapie, immuntherapie und alle kombinationen davon |
| EP3638367A4 (de) | 2017-08-02 | 2021-07-21 | The University of Chicago | Nanoskalige metallorganische schichten und metallorganische nanoplatten für die röntgenstrahlinduzierte photodynamische therapie, strahlentherapie, dynamische strahlentherapie, chemotherapie, immuntherapie und eine beliebige kombination davon |
| EP4310184A3 (de) | 2018-02-23 | 2024-05-01 | Meso Scale Technologies, LLC. | Verfahren zum screenen von antigen-bindenden molekülen durch normalisierung auf die konzentration eines antigen-bindenden moleküls |
| US12480940B2 (en) | 2018-05-17 | 2025-11-25 | Meso Scale Technologies, Llc. | Methods for isolating surface marker displaying agents |
| WO2020086751A1 (en) | 2018-10-23 | 2020-04-30 | Meso Scale Technologies, Llc. | Methods for isolating surface marker displaying agents |
| AU2019418498A1 (en) | 2019-01-03 | 2021-07-15 | Meso Scale Technologies, Llc | Compositions and methods for carrying out assay measurements |
| CN120098057A (zh) | 2019-03-01 | 2025-06-06 | 中尺度技术有限责任公司 | 用于免疫方法的被电化学发光标记的探针、使用这类探针的方法和包含这类探针的试剂盒 |
| CN120665985A (zh) | 2019-06-07 | 2025-09-19 | 豪夫迈·罗氏有限公司 | 杂交全lna寡核苷酸 |
| IL325928A (en) | 2019-07-16 | 2026-03-01 | Meso Scale Technologies Llc | Testing instruments, methods and reagents |
| US20240018571A1 (en) | 2020-05-19 | 2024-01-18 | Meso Scale Technologies, Llc. | Methods, compositions, and kits for nucleic acid detection |
| EP4176263A1 (de) | 2020-07-01 | 2023-05-10 | Meso Scale Technologies, LLC | Zusammensetzungen und verfahren für assay-messungen |
| AU2021327754A1 (en) | 2020-08-21 | 2023-03-30 | Meso Scale Technologies, Llc. | Electrochemical cells with auxiliary electrodes having a defined interface potential and methods of using them |
| EP4208720A2 (de) | 2020-09-04 | 2023-07-12 | Meso Scale Technologies, LLC | Verfahren zur isolierung von markern für die oberfläche des zentralen nervensystems |
| JP2023554517A (ja) | 2020-12-22 | 2023-12-27 | エフ． ホフマン－ラ ロシュ アーゲー | 試料中の目的の分析物を検出するための方法 |
| WO2022231900A1 (en) | 2021-04-26 | 2022-11-03 | Meso Scale Technologies, Llc. | Methods for isolating and analyzing a target analyte encapsulated by a surface marker displaying agent |
| CA3228270A1 (en) | 2021-08-13 | 2023-02-16 | Meso Scale Technologies, Llc. | Electrochemical cell devices and methods of manufacturing |
| CN118922555A (zh) | 2021-12-30 | 2024-11-08 | 中尺度技术有限责任公司 | 用于电化学发光检测的方法 |
| JP2025501000A (ja) | 2022-01-04 | 2025-01-15 | メソ スケール テクノロジーズ エルエルシー | 電気化学セルデバイスおよびその製造方法 |
| JP2025506652A (ja) | 2022-02-18 | 2025-03-13 | エフ． ホフマン－ラ ロシュ アーゲー | 試料中の目的の分析物を検出するための方法 |
| WO2023212315A2 (en) | 2022-04-29 | 2023-11-02 | Meso Scale Technologies, Llc. | Methods for detecting and isolating extracellular vesicles |
| KR20250164185A (ko) | 2023-02-15 | 2025-11-24 | 메소 스케일 테크놀러지즈, 엘엘시 | 전기화학 전지 장치 및 제조 방법 |
| WO2024242845A1 (en) | 2023-05-24 | 2024-11-28 | Meso Scale Technologies, Llc. | Methods for assessing colorectal cancer using extracellular vesicles |
| WO2026039455A1 (en) | 2024-08-13 | 2026-02-19 | Meso Scale Technologies, Llc. | Detection of nucleic acids |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3905871A (en) * | 1971-05-14 | 1975-09-16 | Syva Co | Lactam conjugates to enzymes |
| EP0050965A1 (de) * | 1980-10-23 | 1982-05-05 | Takeda Chemical Industries, Ltd. | Beta-Lactamase inhibierende Zusammensetzung |
| GB8305324D0 (en) * | 1983-02-25 | 1983-03-30 | Unilever Plc | Microbiological test processes |
| US4470459A (en) * | 1983-05-09 | 1984-09-11 | Halliburton Company | Apparatus and method for controlled temperature heating of volumes of hydrocarbonaceous materials in earth formations |
| US5310687A (en) * | 1984-10-31 | 1994-05-10 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US4764462A (en) * | 1985-08-23 | 1988-08-16 | Georgetown University | Detectably labeled cephalosporin assay for beta-lactamase |
| US5147806A (en) * | 1988-04-29 | 1992-09-15 | Igen, Inc. | Method and apparatus for conducting electrochemiluminescence measurements |
| US5057302A (en) * | 1987-02-13 | 1991-10-15 | Abbott Laboratories | Bifunctional chelating agents |
| US5321143A (en) * | 1988-05-26 | 1994-06-14 | Massachusetts Institute Of Technology | Ruthenium-catalyzed production of cyclic sulfates |
| US5235808A (en) * | 1990-02-12 | 1993-08-17 | General Electric Company | Exhaust nozzle including idle thrust spoiling |
| US5264346A (en) * | 1991-06-03 | 1993-11-23 | Chen Kirk C S | Colorimetric method for beta-lactamase assay and its applications |
| US5643713A (en) * | 1995-06-07 | 1997-07-01 | Liang; Pam | Electrochemiluminescent monitoring of compounds |
| CA2223027A1 (en) * | 1995-06-07 | 1996-12-19 | Igen, Inc. | Electrochemiluminescent enzyme immunoassay |
-
1995
- 1995-01-04 US US08/368,429 patent/US5641623A/en not_active Expired - Fee Related
-
1996
- 1996-01-04 WO PCT/US1996/000120 patent/WO1996021039A1/en not_active Ceased
- 1996-01-04 JP JP08521217A patent/JP3122468B2/ja not_active Expired - Fee Related
- 1996-01-04 EP EP96903355A patent/EP0801687B1/de not_active Expired - Lifetime
- 1996-01-04 KR KR1019970704591A patent/KR100444250B1/ko not_active Expired - Fee Related
- 1996-01-04 AU AU47466/96A patent/AU711795B2/en not_active Ceased
- 1996-01-04 DE DE69630775T patent/DE69630775T2/de not_active Expired - Fee Related
- 1996-01-04 AT AT96903355T patent/ATE254665T1/de not_active IP Right Cessation
- 1996-01-04 CA CA002209546A patent/CA2209546A1/en not_active Abandoned
-
1997
- 1997-06-23 US US08/880,210 patent/US6120986A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0801687A4 (de) | 1999-11-17 |
| JPH11502101A (ja) | 1999-02-23 |
| WO1996021039A1 (en) | 1996-07-11 |
| AU4746696A (en) | 1996-07-24 |
| US5641623A (en) | 1997-06-24 |
| EP0801687B1 (de) | 2003-11-19 |
| CA2209546A1 (en) | 1996-07-11 |
| JP3122468B2 (ja) | 2001-01-09 |
| DE69630775T2 (de) | 2004-09-30 |
| AU711795B2 (en) | 1999-10-21 |
| US6120986A (en) | 2000-09-19 |
| DE69630775D1 (de) | 2003-12-24 |
| KR100444250B1 (ko) | 2004-12-13 |
| EP0801687A1 (de) | 1997-10-22 |
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