ATE255111T1 - Abeo-ergolinderivate als 5ht1a liganden - Google Patents

Abeo-ergolinderivate als 5ht1a liganden

Info

Publication number
ATE255111T1
ATE255111T1 AT95916653T AT95916653T ATE255111T1 AT E255111 T1 ATE255111 T1 AT E255111T1 AT 95916653 T AT95916653 T AT 95916653T AT 95916653 T AT95916653 T AT 95916653T AT E255111 T1 ATE255111 T1 AT E255111T1
Authority
AT
Austria
Prior art keywords
group
alkyl
hydrogen
phenyl
abeo
Prior art date
Application number
AT95916653T
Other languages
English (en)
Inventor
Sergio Mantegani
Tiziano Bandiera
Enzo Brambilla
Carla Caccia
Nicola Carfagna
Original Assignee
Pharmacia Italia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Italia Spa filed Critical Pharmacia Italia Spa
Application granted granted Critical
Publication of ATE255111T1 publication Critical patent/ATE255111T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT95916653T 1994-04-18 1995-04-13 Abeo-ergolinderivate als 5ht1a liganden ATE255111T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9407637A GB9407637D0 (en) 1994-04-18 1994-04-18 Serotoninergic abeo-ergoline derivatives
PCT/EP1995/001398 WO1995028403A1 (en) 1994-04-18 1995-04-13 Abeo-ergoline derivatives as 5ht1a ligands

Publications (1)

Publication Number Publication Date
ATE255111T1 true ATE255111T1 (de) 2003-12-15

Family

ID=10753700

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95916653T ATE255111T1 (de) 1994-04-18 1995-04-13 Abeo-ergolinderivate als 5ht1a liganden

Country Status (16)

Country Link
US (1) US6284896B1 (de)
EP (1) EP0708777B1 (de)
JP (1) JPH08512059A (de)
KR (1) KR960703126A (de)
CN (1) CN1126996A (de)
AT (1) ATE255111T1 (de)
CA (1) CA2163773A1 (de)
DE (1) DE69532187T2 (de)
ES (1) ES2211903T3 (de)
FI (1) FI955933A0 (de)
GB (1) GB9407637D0 (de)
HU (1) HUT73430A (de)
NO (1) NO955071L (de)
NZ (1) NZ284472A (de)
PL (1) PL312229A1 (de)
WO (1) WO1995028403A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2825100A (en) * 1999-03-30 2000-10-23 Shionogi & Co., Ltd. Heterocyclic compounds having affinities for serotonin receptors
MXPA03001472A (es) * 2000-08-16 2003-06-06 Upjohn Co Compuestos para el tratamiento de trastornos adictivos.
US6858640B2 (en) 2000-09-22 2005-02-22 Shionogi & Co., Ltd. Tricyclic indole compounds having affinity for serotonin receptor
AU2024292749A1 (en) * 2023-07-14 2026-03-05 2A Biosciences, Inc. Substituted ergolines

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1482871A (en) * 1975-03-18 1977-08-17 Farmaceutici Italia Tetracyclic indole derivatives
IL59507A (en) 1979-03-16 1984-01-31 Erba Farmitalia 5-(10-9)abeo-6-methylergoline derivatives,their preparation and pharmaceutical compositions containing them
GB8714767D0 (en) 1987-06-24 1987-07-29 Erba Farmitalia Egoline derivatives
GB8612366D0 (en) 1986-05-21 1986-06-25 Erba Farmitalia Ergoline esters
GB8702364D0 (en) 1987-02-03 1987-03-11 Erba Farmitalia Ergolinyl heterocycles
DE3868866D1 (de) 1987-11-20 1992-04-09 Erba Carlo Spa Ergolinderivate mit antiparkinsonwirkung.
RU2074857C1 (ru) 1990-01-25 1997-03-10 Фармиталиа Карло Эрба С.Р.Л. Способ получения производных эрголина
US5244911A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz(cd)indoles and pharmaceutical use thereof
DK0628042T3 (da) 1992-12-24 2001-11-12 Pharmacia & Upjohn Spa Serotoninerge ergolinderivater

Also Published As

Publication number Publication date
CN1126996A (zh) 1996-07-17
ES2211903T3 (es) 2004-07-16
DE69532187D1 (de) 2004-01-08
AU2307395A (en) 1995-11-10
US6284896B1 (en) 2001-09-04
AU685268B2 (en) 1998-01-15
EP0708777A1 (de) 1996-05-01
JPH08512059A (ja) 1996-12-17
FI955933A7 (fi) 1995-12-11
HUT73430A (en) 1996-07-29
CA2163773A1 (en) 1995-10-26
FI955933L (fi) 1995-12-11
FI955933A0 (fi) 1995-12-11
PL312229A1 (en) 1996-04-01
KR960703126A (ko) 1996-06-19
WO1995028403A1 (en) 1995-10-26
DE69532187T2 (de) 2004-09-02
NO955071D0 (no) 1995-12-14
NO955071L (no) 1995-12-14
EP0708777B1 (de) 2003-11-26
NZ284472A (en) 1998-01-26
GB9407637D0 (en) 1994-06-08
HU9503718D0 (en) 1996-03-28

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties