ATE255415T1 - Verfahren und präparate für die prophylaxe und therapie von mit endotoxin verbundenen zuständen - Google Patents

Verfahren und präparate für die prophylaxe und therapie von mit endotoxin verbundenen zuständen

Info

Publication number
ATE255415T1
ATE255415T1 AT95930812T AT95930812T ATE255415T1 AT E255415 T1 ATE255415 T1 AT E255415T1 AT 95930812 T AT95930812 T AT 95930812T AT 95930812 T AT95930812 T AT 95930812T AT E255415 T1 ATE255415 T1 AT E255415T1
Authority
AT
Austria
Prior art keywords
endotoxin
prophylaxis
preparations
therapy
methods
Prior art date
Application number
AT95930812T
Other languages
English (en)
Inventor
Daniel M Levine
Thomas S Parker
Albert L Rubin
Bruce R Gordon
Stuart D Saal
Original Assignee
Sepsicure L L C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26965092&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE255415(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/288,568 external-priority patent/US5506218A/en
Application filed by Sepsicure L L C filed Critical Sepsicure L L C
Application granted granted Critical
Publication of ATE255415T1 publication Critical patent/ATE255415T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1275—Lipoproteins or protein-free species thereof, e.g. chylomicrons; Artificial high-density lipoproteins [HDL], low-density lipoproteins [LDL] or very-low-density lipoproteins [VLDL]; Precursors thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT95930812T 1994-08-10 1995-08-10 Verfahren und präparate für die prophylaxe und therapie von mit endotoxin verbundenen zuständen ATE255415T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/288,568 US5506218A (en) 1992-08-12 1994-08-10 Methods useful in endotoxin based therapy
US08/487,459 US5674855A (en) 1992-08-12 1995-06-07 Methods and compositions useful in prophylaxis and therapy of endotoxin related conditions
PCT/US1995/010189 WO1996004916A1 (en) 1994-08-10 1995-08-10 Methods and compositions useful in prophylaxis and therapy of endotoxin related conditions

Publications (1)

Publication Number Publication Date
ATE255415T1 true ATE255415T1 (de) 2003-12-15

Family

ID=26965092

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95930812T ATE255415T1 (de) 1994-08-10 1995-08-10 Verfahren und präparate für die prophylaxe und therapie von mit endotoxin verbundenen zuständen

Country Status (26)

Country Link
US (1) US5674855A (de)
EP (1) EP0767666B1 (de)
JP (1) JP3818660B2 (de)
CN (1) CN1137688C (de)
AP (1) AP782A (de)
AT (1) ATE255415T1 (de)
AU (1) AU703861C (de)
BG (1) BG61967B1 (de)
BR (1) BR9508584A (de)
CA (1) CA2196906C (de)
CY (1) CY2514B1 (de)
CZ (1) CZ287614B6 (de)
DE (1) DE69532239T2 (de)
DK (1) DK0767666T3 (de)
ES (1) ES2211915T3 (de)
FI (1) FI118035B (de)
HU (1) HUT77605A (de)
NO (1) NO313786B1 (de)
NZ (1) NZ292315A (de)
OA (2) OA11737A (de)
PL (1) PL182043B1 (de)
PT (1) PT767666E (de)
RO (1) RO115782B1 (de)
RU (1) RU2174839C2 (de)
SK (1) SK282493B6 (de)
WO (1) WO1996004916A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6004925A (en) 1997-09-29 1999-12-21 J. L. Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6046166A (en) 1997-09-29 2000-04-04 Jean-Louis Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6518412B1 (en) 1997-09-29 2003-02-11 Jean-Louis Dasseux Gene therapy approaches to supply apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6037323A (en) * 1997-09-29 2000-03-14 Jean-Louis Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
EP1158989B1 (de) * 1999-03-09 2007-06-20 Anker, Stefan Endotoxinhemmern zur behandlung von kachexie
US20030032674A1 (en) * 2001-08-13 2003-02-13 Hwang Daniel H. Use of unsaturated fatty acids to treat severe inflammatory diseases
JP2006507223A (ja) 2002-05-17 2006-03-02 エスペリオン セラピューティクス，インコーポレイテッド 脂質代謝異常疾患の治療方法
JP2006516614A (ja) * 2003-02-05 2006-07-06 エヌ．ブイ．・ヌートリシア 敗血症の予防および／または治療のための経腸組成物
US7754230B2 (en) * 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
MXPA06013437A (es) 2004-05-19 2007-03-23 Los Angeles Biomed Res Inst Uso de un detergente para la eliminacion no quirurgica de grasa.
US20060127468A1 (en) 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
UA89545C2 (uk) * 2005-08-29 2010-02-10 Сепсикюр Л.Л.К. Спосіб лікування чи попередження станів, викликаних грампозитивними бактеріями
GB0522942D0 (en) 2005-11-10 2005-12-21 Leigh Steven Dissolution composition
ES2402823T3 (es) 2006-06-01 2013-05-09 Institut De Cardiologie De Montreal Compuesto para uso en el tratamiento de estenosis valvular
KR100785656B1 (ko) * 2007-05-14 2007-12-17 재단법인서울대학교산학협력재단 소염제로 사용되는 소디움글리코콜레이트 또는 그 유도체
RU2351351C1 (ru) * 2007-08-08 2009-04-10 Тихоокеанский Институт Биоорганической Химии Дальневосточного Отделения Российской Академии Наук (Тибох Дво Ран) Средство, повышающее неспецифическую сопротивляемость организма к бактериальным эндотоксинам
JP5719783B2 (ja) 2009-02-16 2015-05-20 セレニス セラピューティクス ホールディング エスアー アポリポタンパクａ−ｉ模倣物
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
MX363465B (es) 2011-02-18 2019-03-25 Kythera Biopharmaceuticals Inc Tratamiento de la grasa submental.
US8653058B2 (en) 2011-04-05 2014-02-18 Kythera Biopharmaceuticals, Inc. Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits
US9023833B2 (en) * 2012-12-18 2015-05-05 Sepsicure, LLC Method for treating sepsis in patients with albumin, cholesterol and HDL levels above minimum thresholds

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115313A (en) * 1974-10-08 1978-09-19 Irving Lyon Bile acid emulsions
DE2556592C2 (de) * 1975-12-16 1986-10-09 A. Nattermann & Cie GmbH, 5000 Köln Arzneimittelzubereitungen auf Basis öliger Lösungen von Phospholipiden
US4314997A (en) * 1980-10-06 1982-02-09 Edward Shanbrom Purification of plasma protein products
IL63734A (en) * 1981-09-04 1985-07-31 Yeda Res & Dev Lipid fraction,its preparation and pharmaceutical compositions containing same
CA1237671A (en) * 1983-08-01 1988-06-07 Michael W. Fountain Enhancement of pharmaceutical activity
JPS6193111A (ja) * 1984-05-28 1986-05-12 Funayama Seizo 発熱性物質除去方法
US5032585A (en) * 1987-02-17 1991-07-16 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for surfactant replacement therapy
AU614465B2 (en) * 1989-04-05 1991-08-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions
DE4017979A1 (de) * 1990-06-05 1991-12-12 Meyer Lucas Gmbh & Co Lipid- bzw. phospholipid-zusammensetzungen sowie diese enthaltendes mittel zur behandlung von erkrankungen sowie auf die zellmembrane zurueckzufuehrende stoerungen
BR9201168A (pt) * 1992-04-02 1994-04-12 Zerbini E J Fundacao Microemulsoes usadas como velculo para carregar quimioterapicos as celulas neoplasicas

Also Published As

Publication number Publication date
OA11737A (en) 2005-05-12
BG61967B1 (bg) 1998-11-30
CN1137688C (zh) 2004-02-11
CA2196906A1 (en) 1996-02-22
EP0767666A4 (de) 1998-10-07
FI118035B (fi) 2007-06-15
HUT77605A (hu) 1998-06-29
WO1996004916A1 (en) 1996-02-22
RO115782B1 (ro) 2000-06-30
AP9700921A0 (en) 1997-01-31
CZ287614B6 (en) 2001-01-17
JPH10504037A (ja) 1998-04-14
FI970534L (fi) 1997-02-07
PL318593A1 (en) 1997-06-23
BG101288A (en) 1997-09-30
BR9508584A (pt) 1997-10-21
AU703861B2 (en) 1999-04-01
FI970534A0 (fi) 1997-02-07
SK17697A3 (en) 1997-09-10
ES2211915T3 (es) 2004-07-16
NO970582L (no) 1997-04-07
AP782A (en) 1999-11-15
RU2174839C2 (ru) 2001-10-20
DE69532239T2 (de) 2004-10-21
CN1158087A (zh) 1997-08-27
PT767666E (pt) 2004-04-30
EP0767666A1 (de) 1997-04-16
EP0767666B1 (de) 2003-12-03
OA10598A (en) 2002-07-15
US5674855A (en) 1997-10-07
CY2514B1 (en) 2005-12-23
NO313786B1 (no) 2002-12-02
AU703861C (en) 2001-12-20
JP3818660B2 (ja) 2006-09-06
AU3405295A (en) 1996-03-07
CA2196906C (en) 2004-03-02
DK0767666T3 (da) 2004-04-05
CZ37197A3 (en) 1997-10-15
NO970582D0 (no) 1997-02-07
NZ292315A (en) 1998-10-28
PL182043B1 (pl) 2001-10-31
SK282493B6 (sk) 2002-02-05
DE69532239D1 (de) 2004-01-15
HK1003709A1 (en) 1998-11-06

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