DK0767666T3 - Fremgangsmåder og præparater, der er anvendelige ved profylakse og behandling af endotoksin-relaterede tilstande - Google Patents

Fremgangsmåder og præparater, der er anvendelige ved profylakse og behandling af endotoksin-relaterede tilstande

Info

Publication number
DK0767666T3
DK0767666T3 DK95930812T DK95930812T DK0767666T3 DK 0767666 T3 DK0767666 T3 DK 0767666T3 DK 95930812 T DK95930812 T DK 95930812T DK 95930812 T DK95930812 T DK 95930812T DK 0767666 T3 DK0767666 T3 DK 0767666T3
Authority
DK
Denmark
Prior art keywords
endotoxin
prophylaxis
treatment
methods
related conditions
Prior art date
Application number
DK95930812T
Other languages
English (en)
Inventor
Daniel M Levine
Thomas S Parker
Albert L Rubin
Bruce R Gordon
Stuart D Saal
Original Assignee
Sepsicure L L C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26965092&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0767666(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/288,568 external-priority patent/US5506218A/en
Application filed by Sepsicure L L C filed Critical Sepsicure L L C
Application granted granted Critical
Publication of DK0767666T3 publication Critical patent/DK0767666T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1275—Lipoproteins or protein-free species thereof, e.g. chylomicrons; Artificial high-density lipoproteins [HDL], low-density lipoproteins [LDL] or very-low-density lipoproteins [VLDL]; Precursors thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK95930812T 1994-08-10 1995-08-10 Fremgangsmåder og præparater, der er anvendelige ved profylakse og behandling af endotoksin-relaterede tilstande DK0767666T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/288,568 US5506218A (en) 1992-08-12 1994-08-10 Methods useful in endotoxin based therapy
US08/487,459 US5674855A (en) 1992-08-12 1995-06-07 Methods and compositions useful in prophylaxis and therapy of endotoxin related conditions
PCT/US1995/010189 WO1996004916A1 (en) 1994-08-10 1995-08-10 Methods and compositions useful in prophylaxis and therapy of endotoxin related conditions

Publications (1)

Publication Number Publication Date
DK0767666T3 true DK0767666T3 (da) 2004-04-05

Family

ID=26965092

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95930812T DK0767666T3 (da) 1994-08-10 1995-08-10 Fremgangsmåder og præparater, der er anvendelige ved profylakse og behandling af endotoksin-relaterede tilstande

Country Status (26)

Country Link
US (1) US5674855A (da)
EP (1) EP0767666B1 (da)
JP (1) JP3818660B2 (da)
CN (1) CN1137688C (da)
AP (1) AP782A (da)
AT (1) ATE255415T1 (da)
AU (1) AU703861C (da)
BG (1) BG61967B1 (da)
BR (1) BR9508584A (da)
CA (1) CA2196906C (da)
CY (1) CY2514B1 (da)
CZ (1) CZ287614B6 (da)
DE (1) DE69532239T2 (da)
DK (1) DK0767666T3 (da)
ES (1) ES2211915T3 (da)
FI (1) FI118035B (da)
HU (1) HUT77605A (da)
NO (1) NO313786B1 (da)
NZ (1) NZ292315A (da)
OA (2) OA11737A (da)
PL (1) PL182043B1 (da)
PT (1) PT767666E (da)
RO (1) RO115782B1 (da)
RU (1) RU2174839C2 (da)
SK (1) SK282493B6 (da)
WO (1) WO1996004916A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046166A (en) 1997-09-29 2000-04-04 Jean-Louis Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6004925A (en) 1997-09-29 1999-12-21 J. L. Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6518412B1 (en) 1997-09-29 2003-02-11 Jean-Louis Dasseux Gene therapy approaches to supply apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6037323A (en) 1997-09-29 2000-03-14 Jean-Louis Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
ATE365043T1 (de) * 1999-03-09 2007-07-15 Anker Stefan Endotoxinhemmern zur behandlung von kachexie
US20030032674A1 (en) * 2001-08-13 2003-02-13 Hwang Daniel H. Use of unsaturated fatty acids to treat severe inflammatory diseases
AU2003239489A1 (en) 2002-05-17 2003-12-02 Esperion Therapeutics, Inc. Method of treating dyslipidemic disorders
JP2006516614A (ja) * 2003-02-05 2006-07-06 エヌ．ブイ．・ヌートリシア 敗血症の予防および／または治療のための経腸組成物
US20060127468A1 (en) 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
US7754230B2 (en) * 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
ES2660172T3 (es) * 2004-05-19 2018-03-21 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Composición inyectable que comprende desoxicolato de sodio
EP1933856A4 (en) * 2005-08-29 2008-11-19 Sepsicure L L C METHOD OF TREATING OR PREVENTING CONDITIONS INDUCED BY GRAM POSITIVE BACTERIA
GB0522942D0 (en) 2005-11-10 2005-12-21 Leigh Steven Dissolution composition
CA2653840A1 (en) 2006-06-01 2007-12-06 Institut De Cardiologie De Montreal Use of a peptide/phospholipid complex acting as a reverse lipid transport agonist for treatment of valvular stenosis
KR100785656B1 (ko) * 2007-05-14 2007-12-17 재단법인서울대학교산학협력재단 소염제로 사용되는 소디움글리코콜레이트 또는 그 유도체
RU2351351C1 (ru) * 2007-08-08 2009-04-10 Тихоокеанский Институт Биоорганической Химии Дальневосточного Отделения Российской Академии Наук (Тибох Дво Ран) Средство, повышающее неспецифическую сопротивляемость организма к бактериальным эндотоксинам
LT2939683T (lt) 2009-02-16 2017-03-27 Cerenis Therapeutics Holding Sa Apolipoproteino a-i mimetikai
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
US20120237492A1 (en) 2011-02-18 2012-09-20 Kythera Biopharmaceuticals, Inc. Treatment of submental fat
US8653058B2 (en) 2011-04-05 2014-02-18 Kythera Biopharmaceuticals, Inc. Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits
US9023833B2 (en) * 2012-12-18 2015-05-05 Sepsicure, LLC Method for treating sepsis in patients with albumin, cholesterol and HDL levels above minimum thresholds

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115313A (en) * 1974-10-08 1978-09-19 Irving Lyon Bile acid emulsions
DE2556592C2 (de) * 1975-12-16 1986-10-09 A. Nattermann & Cie GmbH, 5000 Köln Arzneimittelzubereitungen auf Basis öliger Lösungen von Phospholipiden
US4314997A (en) * 1980-10-06 1982-02-09 Edward Shanbrom Purification of plasma protein products
IL63734A (en) * 1981-09-04 1985-07-31 Yeda Res & Dev Lipid fraction,its preparation and pharmaceutical compositions containing same
CA1237671A (en) * 1983-08-01 1988-06-07 Michael W. Fountain Enhancement of pharmaceutical activity
JPS6193111A (ja) * 1984-05-28 1986-05-12 Funayama Seizo 発熱性物質除去方法
US5032585A (en) * 1987-02-17 1991-07-16 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for surfactant replacement therapy
AU614465B2 (en) * 1989-04-05 1991-08-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions
DE4017979A1 (de) * 1990-06-05 1991-12-12 Meyer Lucas Gmbh & Co Lipid- bzw. phospholipid-zusammensetzungen sowie diese enthaltendes mittel zur behandlung von erkrankungen sowie auf die zellmembrane zurueckzufuehrende stoerungen
BR9201168A (pt) * 1992-04-02 1994-04-12 Zerbini E J Fundacao Microemulsoes usadas como velculo para carregar quimioterapicos as celulas neoplasicas

Also Published As

Publication number Publication date
NZ292315A (en) 1998-10-28
JP3818660B2 (ja) 2006-09-06
CY2514B1 (en) 2005-12-23
OA10598A (en) 2002-07-15
HK1003709A1 (en) 1998-11-06
AU703861C (en) 2001-12-20
FI970534L (fi) 1997-02-07
EP0767666B1 (en) 2003-12-03
WO1996004916A1 (en) 1996-02-22
CZ287614B6 (en) 2001-01-17
OA11737A (en) 2005-05-12
NO313786B1 (no) 2002-12-02
HUT77605A (hu) 1998-06-29
AP9700921A0 (en) 1997-01-31
SK282493B6 (sk) 2002-02-05
NO970582D0 (no) 1997-02-07
AP782A (en) 1999-11-15
US5674855A (en) 1997-10-07
DE69532239T2 (de) 2004-10-21
DE69532239D1 (de) 2004-01-15
ATE255415T1 (de) 2003-12-15
PT767666E (pt) 2004-04-30
AU3405295A (en) 1996-03-07
CA2196906C (en) 2004-03-02
RU2174839C2 (ru) 2001-10-20
SK17697A3 (en) 1997-09-10
EP0767666A4 (en) 1998-10-07
CZ37197A3 (en) 1997-10-15
NO970582L (no) 1997-04-07
CN1137688C (zh) 2004-02-11
JPH10504037A (ja) 1998-04-14
BR9508584A (pt) 1997-10-21
EP0767666A1 (en) 1997-04-16
CN1158087A (zh) 1997-08-27
BG101288A (en) 1997-09-30
BG61967B1 (bg) 1998-11-30
PL318593A1 (en) 1997-06-23
PL182043B1 (pl) 2001-10-31
ES2211915T3 (es) 2004-07-16
RO115782B1 (ro) 2000-06-30
CA2196906A1 (en) 1996-02-22
AU703861B2 (en) 1999-04-01
FI118035B (fi) 2007-06-15
FI970534A0 (fi) 1997-02-07

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