ATE255909T1 - Konservierungssystem für topisch verabreichbare pharmazeutische zusammensetzungen - Google Patents

Konservierungssystem für topisch verabreichbare pharmazeutische zusammensetzungen

Info

Publication number
ATE255909T1
ATE255909T1 AT99951565T AT99951565T ATE255909T1 AT E255909 T1 ATE255909 T1 AT E255909T1 AT 99951565 T AT99951565 T AT 99951565T AT 99951565 T AT99951565 T AT 99951565T AT E255909 T1 ATE255909 T1 AT E255909T1
Authority
AT
Austria
Prior art keywords
pharmaceutical compositions
topically administered
preservation system
administered pharmaceutical
preservation
Prior art date
Application number
AT99951565T
Other languages
English (en)
Inventor
Ernesto J Castillo
Steven Howard Gerson
Wesley Wehsin Han
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Application granted granted Critical
Publication of ATE255909T1 publication Critical patent/ATE255909T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
AT99951565T 1998-10-27 1999-09-21 Konservierungssystem für topisch verabreichbare pharmazeutische zusammensetzungen ATE255909T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10582098P 1998-10-27 1998-10-27
PCT/US1999/022004 WO2000024425A1 (en) 1998-10-27 1999-09-21 Preservative system for topically administrable pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ATE255909T1 true ATE255909T1 (de) 2003-12-15

Family

ID=22307959

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99951565T ATE255909T1 (de) 1998-10-27 1999-09-21 Konservierungssystem für topisch verabreichbare pharmazeutische zusammensetzungen

Country Status (14)

Country Link
US (1) US6211238B1 (de)
EP (1) EP1124582B1 (de)
JP (1) JP2002528423A (de)
AR (1) AR020964A1 (de)
AT (1) ATE255909T1 (de)
AU (1) AU758450B2 (de)
BR (1) BR9914813A (de)
CA (1) CA2340226A1 (de)
DE (1) DE69913559T2 (de)
DK (1) DK1124582T3 (de)
ES (1) ES2209515T3 (de)
PT (1) PT1124582E (de)
TW (1) TW534816B (de)
WO (1) WO2000024425A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6146622A (en) * 1998-10-27 2000-11-14 Alcon Laboratories, Inc. Use of certain anionic amino acid based surfactants to enhance antimicrobial effectiveness of topically administrable pharmaceutical compositions
US6444710B1 (en) 1998-10-27 2002-09-03 Alcon Manufacturing, Ltd. Use of certain fatty acid/amino acid soaps to enhance antimicrobial effectiveness of topically administrable pharmaceutical compositions
ES2171147B1 (es) * 2001-02-06 2003-12-16 Esteve Labor Dr Preparacion para usos veterinarios.
JP4424643B2 (ja) * 2002-02-13 2010-03-03 株式会社バイオバンク 抗真菌剤の製造方法
JP4725699B2 (ja) * 2002-04-08 2011-07-13 ライオン株式会社 眼科用組成物及び眼科用組成物配合用防腐剤
JP2010031052A (ja) * 2002-04-08 2010-02-12 Lion Corp 眼科用組成物、及び眼科製剤用防腐組成物
WO2003086332A1 (en) * 2002-04-11 2003-10-23 Dvm Pharmaceuticals, Inc. Antimicrobial wash and carrier solutions, and uses thereof
US20040101506A1 (en) * 2002-11-25 2004-05-27 Fust Charles A. Composition for the prevention and treatment of inflammation of the ear
US20060172972A1 (en) * 2002-12-20 2006-08-03 Chakshu Research Inc Formulation and method for administration of ophthalmologically active agents
US20060177430A1 (en) * 2002-12-20 2006-08-10 Chakshu Research Inc Treatment of ocular disorders with ophthalmic formulations containing methylsulfonylmethane as a transport enhancer
CA2511217A1 (en) 2002-12-20 2004-07-15 Chakshu Research, Inc. Ophthalmic formulation for the prevention and treatment of ocular conditions
US20060166879A1 (en) * 2002-12-20 2006-07-27 Chakshu Research Inc Treatment of conditions associated with the presence of macromolecular aggregates, particularly ophthalmic disorders
US7214391B2 (en) * 2003-06-30 2007-05-08 Usana Health Sciences, Inc. Botanical extract compositions and process for preparing same
US20060019987A1 (en) * 2004-07-23 2006-01-26 Fust Charles A Methods and compositions for inhibiting, destroying, and/or inactivating viruses
US7678578B2 (en) * 2005-02-07 2010-03-16 Beckman Coulter, Inc. Cell permeabilization and stabilization reagent and method of use
EP1907006A2 (de) * 2005-07-15 2008-04-09 Chakshu Research, Inc. Prävention und behandlung von ophthalmischen komplikationen von diabetes
WO2008024846A2 (en) * 2006-08-25 2008-02-28 Allergan, Inc. Brimonidine and timolol compositions
US9161923B2 (en) * 2010-07-02 2015-10-20 Brien Holden Vision Institute Composition for prevention and treatment of contact lens papillary conjunctivitis and allergic eye disease
EP2609933A4 (de) * 2010-08-27 2014-04-09 Wakamoto Pharma Co Ltd Wässrige zusammensetzung zur verabreichung in die augen
WO2013166459A1 (en) 2012-05-03 2013-11-07 Rajiv Bhushan Treating inflammatory conditions and improving oral hygiene using metal modulators with methylsulfonylmethane as transport enhancer
WO2016205574A1 (en) * 2015-06-18 2016-12-22 Common Pharma, Inc Antimicrobial formulations
EP3554233B1 (de) * 2016-12-16 2025-07-23 Aurorium Holdings LLC Quaternäre aminformulierungen und verwendungen davon
US11241443B2 (en) 2017-04-07 2022-02-08 Sun Pharma Advanced Research Company Ltd. Ophthalmic solution of bimatoprost
CN108066283B (zh) * 2017-12-28 2020-03-24 兆科（广州）眼科药物有限公司 一种盐酸左倍他洛尔滴眼液的制备方法
JP6621955B2 (ja) * 2018-03-30 2019-12-18 千寿製薬株式会社 水性液剤
JP6653037B2 (ja) * 2018-03-30 2020-02-26 千寿製薬株式会社 水性液剤

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3275503A (en) 1964-08-26 1966-09-27 Patterson Co C Method for the protection of loci susceptible to the growth of undesired microorganisms
US4380637A (en) 1978-11-30 1983-04-19 Johnson & Johnson/Mona Industries, Inc. Imidazoline phosphobetaines
US4485029A (en) 1984-03-19 1984-11-27 Minnesota Mining And Manufacturing Company Disinfecting method and compositions
US5554367A (en) * 1984-10-31 1996-09-10 Alcon Laboratories, Inc. Compositions for treatment of glaucoma
US4911920A (en) 1986-07-30 1990-03-27 Alcon Laboratories, Inc. Sustained release, comfort formulation for glaucoma therapy
EP0194097B1 (de) 1985-03-01 1990-04-25 The Procter & Gamble Company Milder Reinigungsschaum
CA1302280C (en) * 1986-04-21 1992-06-02 Jon Joseph Kabara Topical antimicrobial pharmaceutical compositions and methods
US5000868A (en) 1987-04-03 1991-03-19 Wittpenn Jr John R Surfactant compositions
US5093126A (en) 1987-09-26 1992-03-03 Alcon Laboratories, Inc. Glaucoma formulations comprising an anionic, polysulfonic acid polymer having mucomimetic properties and a polystyrene sulfonic polymer
US5520920A (en) 1992-08-28 1996-05-28 Alcon Laboratories, Inc. Use of certain anionic surfactants to enhance antimicrobial effectiveness of ophthalmic compositions
AU666957B2 (en) * 1992-08-28 1996-02-29 Alcon Laboratories, Inc. Use of certain anionic surfactants to enhance antimicrobial effectiveness of ophthalmic compositions
US5504113A (en) 1994-03-02 1996-04-02 Allergan, Inc. Enhancement of benzalkonium chloride preservative activity in formulations containing an incompatible drug
US5536305A (en) 1994-06-08 1996-07-16 Yu; Bing Low leaching compositions for wood
CA2189018C (en) 1994-06-20 2001-01-02 Alexander Allan Improvements relating to antimicrobial cleaning compositions
US5494937A (en) 1994-07-22 1996-02-27 Alcon Laboratories, Inc. Saline solution for treating contact lenses
AU3070395A (en) 1994-07-22 1996-02-22 Alcon Laboratories, Inc. Use of low molecular weight amino acids in ophthalmic compositions
US5641480A (en) 1994-12-08 1997-06-24 Lever Brothers Company, Division Of Conopco, Inc. Hair care compositions comprising heteroatom containing alkyl aldonamide compounds
EP0877600B1 (de) * 1996-08-09 2003-10-22 Alcon Manufacturing Ltd. Konservierungssysteme fur cyclodextrine enthaltende arzneimittel
GB9717952D0 (en) 1997-08-22 1997-10-29 Procter & Gamble Cleansing compositions

Also Published As

Publication number Publication date
DK1124582T3 (da) 2004-03-22
TW534816B (en) 2003-06-01
CA2340226A1 (en) 2000-05-04
AU6398299A (en) 2000-05-15
EP1124582B1 (de) 2003-12-10
DE69913559T2 (de) 2004-11-11
PT1124582E (pt) 2004-03-31
DE69913559D1 (de) 2004-01-22
WO2000024425A1 (en) 2000-05-04
ES2209515T3 (es) 2004-06-16
BR9914813A (pt) 2001-07-03
JP2002528423A (ja) 2002-09-03
EP1124582A1 (de) 2001-08-22
AR020964A1 (es) 2002-06-05
AU758450B2 (en) 2003-03-20
US6211238B1 (en) 2001-04-03

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