ATE256664T1 - Herstellung von (s)-decahydroisochinolin-3- carbonsäure-t-butylamid - Google Patents

Herstellung von (s)-decahydroisochinolin-3- carbonsäure-t-butylamid

Info

Publication number: ATE256664T1
Authority: AT; Austria
Prior art keywords: tic; butylamide; carboxylic acid; decahydroisocinoline; production
Prior art date: 1996-02-20

Application number

AT96936615T

Other languages

English (en)

Inventor

David R Allen

Scott Jenkins

Loraine Klein

Robert Erickson

Diana Froen

Original Assignee

Pcbu Services Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-02-20

Filing date

1996-10-18

Publication date

2004-01-15

1996-10-18 Application filed by Pcbu Services Inc filed Critical Pcbu Services Inc

2004-01-15 Application granted granted Critical

2004-01-15 Publication of ATE256664T1 publication Critical patent/ATE256664T1/de

Links

230000015572 biosynthetic process Effects 0.000 abstract 2
NSENYWQRQUNUGD-HACHORDNSA-N (3s)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid Chemical compound C1CCCC2CN[C@H](C(=O)O)CC21 NSENYWQRQUNUGD-HACHORDNSA-N 0.000 abstract 1
DMJXRYSGXCLCFP-LBPRGKRZSA-N (3s)-n-tert-butyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide Chemical compound C1=CC=C2CN[C@H](C(=O)NC(C)(C)C)CC2=C1 DMJXRYSGXCLCFP-LBPRGKRZSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
YBRBMKDOPFTVDT-UHFFFAOYSA-N tert-butylamine Chemical compound CC(C)(C)N YBRBMKDOPFTVDT-UHFFFAOYSA-N 0.000 abstract 1
UWYZHKAOTLEWKK-UHFFFAOYSA-N tetrahydro-isoquinoline Natural products C1=CC=C2CNCCC2=C1 UWYZHKAOTLEWKK-UHFFFAOYSA-N 0.000 abstract 1
150000003526 tetrahydroisoquinolines Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Plural Heterocyclic Compounds (AREA)

AT96936615T 1996-02-20 1996-10-18 Herstellung von (s)-decahydroisochinolin-3- carbonsäure-t-butylamid ATE256664T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/603,744 US5587481A (en)	1996-02-20	1996-02-20	Preparation of (S)-decahydroisoquinoline-3-carboxylic acid t-butylamide
PCT/US1996/016628 WO1997030976A1 (en)	1996-02-20	1996-10-18	Preparation of (s)-decahydroisoquinoline-3-carboxylic acid t-butylamide

Publications (1)

Publication Number	Publication Date
ATE256664T1 true ATE256664T1 (de)	2004-01-15

Family

ID=24416734

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96936615T ATE256664T1 (de)	1996-02-20	1996-10-18	Herstellung von (s)-decahydroisochinolin-3- carbonsäure-t-butylamid

Country Status (10)

Country	Link
US (1)	US5587481A (de)
EP (1)	EP0902781B1 (de)
JP (1)	JP2001506575A (de)
KR (1)	KR19990076981A (de)
AT (1)	ATE256664T1 (de)
AU (1)	AU713924B2 (de)
CA (1)	CA2238478A1 (de)
DE (1)	DE69631169T2 (de)
NO (1)	NO312293B1 (de)
WO (1)	WO1997030976A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2135171T5 (es) †	1995-06-30	2006-03-16	Ajinomoto Co., Inc.	Procedimiento para producir amidas opticamente activas.
IT1301825B1 (it) *	1998-06-26	2000-07-07	Archimica Spa	Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.
CZ299699B6 (cs) *	1998-12-14	2008-10-22	Sk Corporation	Zpusob výroby [3S-(3alfa, 4alfabeta, 8alfabeta)]-N-terc-butyl-dekahydro-3-izochinolinkarboxamidu s vysokým optickým výtežkem
KR100277723B1 (ko)	1998-12-14	2001-01-15	남창우	광학적으로 순수한 데카하이드로이소퀴놀린카르복사미드의 연속제조공정
IT1313682B1 (it) *	1999-11-25	2002-09-09	Archimica Spa	Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.
IT1318986B1 (it) *	2000-10-09	2003-09-19	Archimica S P A Ora Clariant L	Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.
US8627573B2 (en) *	2002-10-05	2014-01-14	Braun Gmbh	Hair-removing device
SG145574A1 (en) *	2003-05-08	2008-09-29	Pfizer	Intermediates useful in the synthesis of hiv-protease inhibitors and methods for preparing the same
CN1300115C (zh) *	2004-03-26	2007-02-14	厦门大学	一种合成1，2，3，4－四氢异喹啉衍生物的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1340588C (en) *	1988-06-13	1999-06-08	Balraj Krishan Handa	Amino acid derivatives
GB8927913D0 (en) *	1989-12-11	1990-02-14	Hoffmann La Roche	Amino acid derivatives
WO1993001174A1 (en) *	1991-07-08	1993-01-21	Glaxo Group Limited	Thiazolidine derivatives and their use as anti-viral compounds
US5256783A (en) *	1991-09-18	1993-10-26	Hoffmann-La Roche Inc.	Method for producing 2-isoquinoline compounds
US5380849A (en) *	1992-11-09	1995-01-10	Merck & Co., Inc.	Process for optically pure decahydroisoqiunolines
ES2135171T5 (es) *	1995-06-30	2006-03-16	Ajinomoto Co., Inc.	Procedimiento para producir amidas opticamente activas.

1996
- 1996-02-20 US US08/603,744 patent/US5587481A/en not_active Expired - Lifetime
- 1996-10-18 WO PCT/US1996/016628 patent/WO1997030976A1/en not_active Ceased
- 1996-10-18 JP JP53011497A patent/JP2001506575A/ja active Pending
- 1996-10-18 EP EP96936615A patent/EP0902781B1/de not_active Expired - Lifetime
- 1996-10-18 CA CA002238478A patent/CA2238478A1/en not_active Abandoned
- 1996-10-18 KR KR1019980705110A patent/KR19990076981A/ko not_active Abandoned
- 1996-10-18 AT AT96936615T patent/ATE256664T1/de not_active IP Right Cessation
- 1996-10-18 AU AU74494/96A patent/AU713924B2/en not_active Ceased
- 1996-10-18 DE DE69631169T patent/DE69631169T2/de not_active Expired - Fee Related
1998
- 1998-08-19 NO NO19983803A patent/NO312293B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE69631169T2 (de)	2004-11-11
DE69631169D1 (de)	2004-01-29
EP0902781A4 (de)	2000-07-19
JP2001506575A (ja)	2001-05-22
NO312293B1 (no)	2002-04-22
NO983803D0 (no)	1998-08-19
EP0902781B1 (de)	2003-12-17
AU713924B2 (en)	1999-12-16
CA2238478A1 (en)	1997-08-28
EP0902781A1 (de)	1999-03-24
WO1997030976A1 (en)	1997-08-28
NO983803L (no)	1998-10-19
US5587481A (en)	1996-12-24
KR19990076981A (ko)	1999-10-25
AU7449496A (en)	1997-09-10

Similar Documents

Publication	Publication Date	Title
ATA86885A (de)	1991-09-15	Verfahren zur herstellung lagerstabiler, schnellzerfallender pharmazeutischer wirkstoff-presslinge
DE3775683D1 (de)	1992-02-13	Herstellung von aromatischen carbonsaeuren.
ATE83659T1 (de)	1993-01-15	Verwendung von indolon-derivaten zur herstellung von arzneimitteln zur behandlung des parkinsonismus.
DE68928956D1 (de)	1999-04-22	Verfahren zur Herstellung von optisch aktivem 1,3-Butanediol
FI872379A7 (fi)	1987-11-30	Menetelmä farmakologisesti vaikuttavien 1,5-diaryyli-3-(w-substituoitu-alempi-alkyyli)-pyratsolien valmistamiseksi
DE69102707D1 (de)	1994-08-04	In einem DNA - Gel stabilisierte Heilwasserliposomen.
EP0680328A1 (de)	1995-11-08	Topisches ketoconazoles arzneimittel.
DE69018071D1 (de)	1995-04-27	Herstellung von peroxysäuren.
ATE107283T1 (de)	1994-07-15	Herstellung von polymorphisch reinem terfenadine.
PL330815A1 (en)	1999-06-07	Derivatives of 1,2,4-benzothiadiasine, their production and application
ATE256664T1 (de)	2004-01-15	Herstellung von (s)-decahydroisochinolin-3- carbonsäure-t-butylamid
DE60007975D1 (de)	2004-03-04	Herstellung von butandiol
DE69810934D1 (de)	2003-02-27	Ribonukleosid-derivat und verfahren zu seiner herstellung
DE3789316D1 (de)	1994-04-14	Herstellung von human-parathyroidhormon.
DE3688937D1 (de)	1993-09-30	Herstellung optisch aktiver aryloxypropanolamine und arylaethanolamine.
PL336640A1 (en)	2000-07-03	Substituted 3,3-diamino-2- propenonitriles, their production and application
DE68900485D1 (de)	1992-01-16	Derivate von phenoxyalkylcarbonsauere und verfahren zu ihrer herstellung.
ATE239736T1 (de)	2003-05-15	Herstellung von clavunalat-salzen
FR2601021B2 (fr)	1988-11-18	Fraction immunogene active a l'egard des bilharzioses, sa preparation, compositions immunisantes la contenant
BG90414A (bg)	1993-12-24	2-азабицикло (2,2,1)-хепт-5- ен-2-оцетна киселина и нейни производни, метод за получаване и приложението им
IT8820274A0 (it)	1988-04-21	Procedimento per la sintesi di esteri ed ammidi dell'acido ossalico.
IT1215409B (it)	1990-02-08	Processo per la sintesi dell'alfa-(1-metiletil)-3,4-dimetossibenzeneacetonitrile.
ES8608887A1 (es)	1986-07-16	Procedimiento para la obtencion de preparados combinados antihipertensores y antianginicos a base de dihidropiridina y bloquear beta.
DE69305250D1 (de)	1996-11-14	Herstellung von Alkandicarbonsäurederivaten
ATE207482T1 (de)	2001-11-15	Verfahren zur herstellung von n2-arylsulfonyl-l- argininamiden

Legal Events

Date	Code	Title	Description
2004-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties