ATE257704T1 - Pharmazeutische zusammensetzungen enthaltend norastemizol. - Google Patents

Pharmazeutische zusammensetzungen enthaltend norastemizol.

Info

Publication number: ATE257704T1
Authority: AT; Austria
Prior art keywords: pharmaceutical compositions; compositions containing; compound; formula; treatment
Prior art date: 1992-09-03

Application number

AT99200247T

Other languages

English (en)

Inventor

Raymond L Woosley

A K Gunnar Aberg

Original Assignee

Sepracor Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-09-03

Filing date

1993-09-03

Publication date

2004-01-15

1993-09-03 Application filed by Sepracor Inc filed Critical Sepracor Inc

2004-01-15 Application granted granted Critical

2004-01-15 Publication of ATE257704T1 publication Critical patent/ATE257704T1/de

Links

SFOVDSLXFUGAIV-UHFFFAOYSA-N 1-[(4-fluorophenyl)methyl]-n-piperidin-4-ylbenzimidazol-2-amine Chemical compound C1=CC(F)=CC=C1CN1C2=CC=CC=C2N=C1NC1CCNCC1 SFOVDSLXFUGAIV-UHFFFAOYSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
206010039085 Rhinitis allergic Diseases 0.000 abstract 1
201000010105 allergic rhinitis Diseases 0.000 abstract 1
206010003119 arrhythmia Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Hematology (AREA)
Endocrinology (AREA)
Otolaryngology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Virology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Steroid Compounds (AREA)

AT99200247T 1992-09-03 1993-09-03 Pharmazeutische zusammensetzungen enthaltend norastemizol. ATE257704T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US94005492A	1992-09-03	1992-09-03

Publications (1)

Publication Number	Publication Date
ATE257704T1 true ATE257704T1 (de)	2004-01-15

Family

ID=25474141

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT93921359T ATE187642T1 (de)	1992-09-03	1993-09-03	Verwendund von norastemizol zur behandlung der allergischen rhinitis
AT99200247T ATE257704T1 (de)	1992-09-03	1993-09-03	Pharmazeutische zusammensetzungen enthaltend norastemizol.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT93921359T ATE187642T1 (de)	1992-09-03	1993-09-03	Verwendund von norastemizol zur behandlung der allergischen rhinitis

Country Status (13)

Country	Link
US (5)	US6130233A (de)
EP (3)	EP0920865B1 (de)
JP (3)	JPH08501083A (de)
AT (2)	ATE187642T1 (de)
AU (1)	AU687746B2 (de)
CA (1)	CA2143610C (de)
DE (3)	DE69327328T2 (de)
DK (2)	DK0920865T3 (de)
ES (2)	ES2210957T3 (de)
GB (1)	GB2285219B (de)
GR (1)	GR3032541T3 (de)
PT (2)	PT920865E (de)
WO (1)	WO1994007495A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6211199B1 (en)	1995-11-17	2001-04-03	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
US6423704B2 (en)	1995-12-20	2002-07-23	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US6194406B1 (en)	1995-12-20	2001-02-27	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US5932571A (en) *	1996-02-21	1999-08-03	Hoechst Marion Roussel, Inc.	Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en)	1996-02-21	1999-12-07	Hoescht Marion Roussel, Inc.	Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5922737A (en) *	1996-02-21	1999-07-13	Hoechst Marion Roussel, Inc.	Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
RU2214245C2 (ru) *	1997-03-26	2003-10-20	Сепракор Инк.	Химически- и термостабильные готовые формы норастемизола
US6248308B1 (en) *	1998-04-14	2001-06-19	Sepracor Inc.	Methods of using norastemizole in combination with leukotriene inhibitors to treat or prevent asthma
CN1518448A (zh) *	2001-06-20	2004-08-04	��鹫˾	用于治疗鼻充血和鼻塞的抗组胺剂
US6627646B2 (en)	2001-07-17	2003-09-30	Sepracor Inc.	Norastemizole polymorphs
US6863901B2 (en)	2001-11-30	2005-03-08	Collegium Pharmaceutical, Inc.	Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration
US6827946B2 (en)	2001-12-05	2004-12-07	Collegium Pharmaceutical, Inc.	Compositions containing both sedative and non-sedative antihistamines
EP2316468A1 (de)	2002-02-22	2011-05-04	Shire LLC	Abgabesystem und Verfahren zum Schutz und zur Verabreichung von Dextroamphetamin
EP2120945A1 (de) *	2007-02-28	2009-11-25	Collegium Pharmaceutical, Inc.	Antihistamin-kombination
US20080306116A1 (en) *	2007-06-08	2008-12-11	Christ Andreas D	Aryloxazole, aryloxadiazole and benzimidazole derivatives
ES2590604T3 (es) *	2008-01-04	2016-11-22	Schabar Research Associates Llc	Composición que comprende un analgésico y un antihistamínico
US8241616B2 (en) *	2008-04-03	2012-08-14	Rohm And Haas Company	Hair styling composition
US11324727B2 (en)	2020-07-15	2022-05-10	Schabar Research Associates, Llc	Unit oral dose compositions composed of naproxen sodium and famotidine for the treatment of acute pain and the reduction of the severity of heartburn and/or the risk of heartburn
KR20230051164A (ko)	2020-07-15	2023-04-17	샤바르 리서치 어소시에이츠 엘엘씨	급성 통증의 치료 및 속쓰림의 중증도 및/또는 위험의 감소를 위한 이부프로펜 및 파모티딘으로 구성된 단위 경구 투여 조성물
US12514846B2 (en)	2020-07-15	2026-01-06	Schabar Research Associates Llc	Unit oral dose compositions composed of ibuprofen or a pharmaceutically acceptable salt thereof and famotidine or a pharmaceutically acceptable salt thereof for the treatment of acute pain and the reduction of the severity and/or risk of heartburn and/or upset stomach

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4219559A (en) *	1979-01-10	1980-08-26	Janssen Pharmaceutica N.V.	N-Heterocyclyl-4-piperidinamines
DE3484096D1 (de) *	1983-11-30	1991-03-14	Janssen Pharmaceutica Nv	Bizyklisches heterozyklyl aufveisende n-(bizyklisches heterozyklyl-4-piperidinamine.
US4835161A (en) *	1986-02-03	1989-05-30	Janssen Pharmaceutica N.V.	Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines
CA1327579C (en) *	1986-02-03	1994-03-08	Frans Eduard Janssens	Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines
US5019591A (en) *	1989-02-17	1991-05-28	Pennsylvania Research Corporation	Method for treating retinopathy and other small vessel disorders associated with diabetes
DK1041990T3 (da)	1997-12-23	2006-10-02	Schering Corp	Præparat til behandling af respiratoriske sygdomme og hudsygdomme med mindst en leukotrien-antagonist og mindst et antihistamin

1993
- 1993-09-03 EP EP99200247A patent/EP0920865B1/de not_active Expired - Lifetime
- 1993-09-03 DE DE69327328T patent/DE69327328T2/de not_active Expired - Fee Related
- 1993-09-03 ES ES99200247T patent/ES2210957T3/es not_active Expired - Lifetime
- 1993-09-03 CA CA002143610A patent/CA2143610C/en not_active Expired - Fee Related
- 1993-09-03 EP EP93921359A patent/EP0658110B1/de not_active Expired - Lifetime
- 1993-09-03 AT AT93921359T patent/ATE187642T1/de not_active IP Right Cessation
- 1993-09-03 DE DE69333387T patent/DE69333387T2/de not_active Expired - Fee Related
- 1993-09-03 GB GB9504329A patent/GB2285219B/en not_active Expired - Fee Related
- 1993-09-03 PT PT99200247T patent/PT920865E/pt unknown
- 1993-09-03 DE DE4394931T patent/DE4394931T1/de not_active Ceased
- 1993-09-03 ES ES93921359T patent/ES2139673T3/es not_active Expired - Lifetime
- 1993-09-03 EP EP02013842A patent/EP1262183A1/de not_active Withdrawn
- 1993-09-03 DK DK99200247T patent/DK0920865T3/da active
- 1993-09-03 JP JP6505651A patent/JPH08501083A/ja active Pending
- 1993-09-03 DK DK93921359T patent/DK0658110T3/da active
- 1993-09-03 AT AT99200247T patent/ATE257704T1/de not_active IP Right Cessation
- 1993-09-03 AU AU48480/93A patent/AU687746B2/en not_active Ceased
- 1993-09-03 WO PCT/US1993/008349 patent/WO1994007495A1/en not_active Ceased
- 1993-09-03 PT PT93921359T patent/PT658110E/pt unknown
1994
- 1994-01-18 US US08/182,685 patent/US6130233A/en not_active Expired - Fee Related
1996
- 1996-12-16 US US08/766,094 patent/US6124320A/en not_active Expired - Fee Related
2000
- 2000-01-12 US US09/481,439 patent/US6187794B1/en not_active Expired - Fee Related
- 2000-02-02 GR GR20000400237T patent/GR3032541T3/el not_active IP Right Cessation
- 2000-04-17 US US09/551,613 patent/US6187795B1/en not_active Expired - Fee Related
- 2000-08-30 US US09/650,645 patent/US6268382B1/en not_active Expired - Fee Related
2002
- 2002-02-28 JP JP2002054842A patent/JP2002255817A/ja active Pending
- 2002-02-28 JP JP2002054838A patent/JP2002308772A/ja active Pending

Also Published As

Publication number	Publication date
EP0658110A1 (de)	1995-06-21
US6187794B1 (en)	2001-02-13
US6187795B1 (en)	2001-02-13
GR3032541T3 (en)	2000-05-31
PT658110E (pt)	2000-06-30
GB9504329D0 (en)	1995-04-26
EP0920865A1 (de)	1999-06-09
GB2285219B (en)	1996-09-11
US6124320A (en)	2000-09-26
GB2285219A (en)	1995-07-05
DE69327328T2 (de)	2000-06-21
ES2210957T3 (es)	2004-07-01
PT920865E (pt)	2004-06-30
DK0658110T3 (da)	2000-04-17
DE69327328D1 (de)	2000-01-20
CA2143610A1 (en)	1994-04-14
DE69333387D1 (de)	2004-02-19
WO1994007495A1 (en)	1994-04-14
DE4394931T1 (de)	1995-07-20
JP2002308772A (ja)	2002-10-23
CA2143610C (en)	2004-08-24
EP1262183A1 (de)	2002-12-04
JP2002255817A (ja)	2002-09-11
AU687746B2 (en)	1998-03-05
JPH08501083A (ja)	1996-02-06
AU4848093A (en)	1994-04-26
DK0920865T3 (da)	2004-04-19
ES2139673T3 (es)	2000-02-16
US6130233A (en)	2000-10-10
ATE187642T1 (de)	2000-01-15
EP0920865B1 (de)	2004-01-14
DE69333387T2 (de)	2004-12-09
EP0658110B1 (de)	1999-12-15
US6268382B1 (en)	2001-07-31

Legal Events

Date

Code

Title

Description

2004-09-15

UEP

Publication of translation of european patent specification

Ref document number: 0920865

Country of ref document: EP

2005-12-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE257704T1 (de)	2004-01-15	Pharmazeutische zusammensetzungen enthaltend norastemizol.
BR9306841A (pt)	1998-12-08	Composição farmacêutica processo para proporcionar um tratamento anti-histamínico o qual não induz qualquer arritmia cardíaca significativa em um paciente ser humano e uso de uma composição para a mnaufactura de um medicamento para uso em um tratamento anti-histamínico
MX9203543A (es)	1992-07-01	Medicamento.
SE9901573D0 (sv)	1999-05-03	New compounds
TR200101633T2 (tr)	2002-06-21	Farmasötik bileşim
ES2136167T3 (es)	1999-11-16	Composiciones de idebenona para tratar la enfermedad de alzheimer.
GB9023701D0 (en)	1990-12-12	Medical treatment
SE9901572D0 (sv)	1999-05-03	New compounds
DK347289D0 (da)	1989-07-13	Terapeutiske forbindelser
DE3688787D1 (de)	1993-09-02	Herstellung eines arzneimittels gegen arthritis und rheumatismus.
BR0014680A (pt)	2002-06-11	Pirróis substituìdos como agentes antiproliferativos para o tratamento de câncer
DE60233578D1 (de)	2009-10-15	Phosphorenthaltende Verbindugnen mit antithrombitische Wirkung