ATE258436T1 - Verwendung von indol-3-essigsäurederivaten in der therapie - Google Patents
Verwendung von indol-3-essigsäurederivaten in der therapieInfo
- Publication number
- ATE258436T1 ATE258436T1 AT01945476T AT01945476T ATE258436T1 AT E258436 T1 ATE258436 T1 AT E258436T1 AT 01945476 T AT01945476 T AT 01945476T AT 01945476 T AT01945476 T AT 01945476T AT E258436 T1 ATE258436 T1 AT E258436T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- groups
- therapy
- indole
- acetic acid
- Prior art date
Links
- 238000002560 therapeutic procedure Methods 0.000 title abstract 2
- SEOVTRFCIGRIMH-UHFFFAOYSA-N indole-3-acetic acid Chemical class C1=CC=C2C(CC(=O)O)=CNC2=C1 SEOVTRFCIGRIMH-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000006575 electron-withdrawing group Chemical group 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000004036 acetal group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002950 deficient Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000010914 gene-directed enzyme pro-drug therapy Methods 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6891—Pre-targeting systems involving an antibody for targeting specific cells
- A61K47/6899—Antibody-Directed Enzyme Prodrug Therapy [ADEPT]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
- C12Y111/01—Peroxidases (1.11.1)
- C12Y111/01007—Peroxidase (1.11.1.7), i.e. horseradish-peroxidase
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0016162.0A GB0016162D0 (en) | 2000-06-30 | 2000-06-30 | Indole-3-acetic acid derivatives |
| PCT/GB2001/002872 WO2002002110A1 (en) | 2000-06-30 | 2001-06-28 | Use of indole-3-acetic acid derivatives in medicine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE258436T1 true ATE258436T1 (de) | 2004-02-15 |
Family
ID=9894821
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01945476T ATE258436T1 (de) | 2000-06-30 | 2001-06-28 | Verwendung von indol-3-essigsäurederivaten in der therapie |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6890948B1 (de) |
| EP (1) | EP1296676B1 (de) |
| AT (1) | ATE258436T1 (de) |
| AU (1) | AU2001267690A1 (de) |
| DE (1) | DE60101914T2 (de) |
| ES (1) | ES2215138T3 (de) |
| GB (1) | GB0016162D0 (de) |
| WO (1) | WO2002002110A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1601348A4 (de) | 2003-02-28 | 2008-12-10 | Oxigene Inc | Zusammensetzungen und verfahren mit verbesserter therapeutischer aktivität |
| BRPI0706353B1 (pt) | 2006-01-05 | 2023-01-24 | Interdigital Patent Holdings, Inc | Método para alocar recursos de rádio em um sistema de comunicação móvel |
| KR100773475B1 (ko) * | 2006-07-07 | 2007-11-05 | 주식회사 웰스킨 | 인돌-3-아세트산을 포함하는 광감작제, 및 이를 포함하는광역학적 치료용 키트 |
| US8580192B2 (en) | 2006-10-31 | 2013-11-12 | Ethicon, Inc. | Sterilization of polymeric materials |
| KR20090001013A (ko) * | 2007-06-29 | 2009-01-08 | 주식회사 웰스킨 | 인돌-3-알킬카복실산을 함유하는 여드름 치료제 및 피지분비 억제제, 및 이를 포함하는 광역학적 치료용 키트 |
| KR101089750B1 (ko) | 2009-11-25 | 2011-12-07 | 중앙대학교 산학협력단 | 5―히드록시인돌초산을 포함하는 광감작용 조성물 및 이를 포함하는 암의 광역학 치료용 조성물 |
| US8748446B2 (en) | 2012-03-03 | 2014-06-10 | Nanoquantum Sciences, Inc. | Halogenated compounds for photodynamic therapy |
| CN105037239B (zh) * | 2015-07-21 | 2018-04-06 | 苏州卡耐博生物技术有限公司 | 一种4‑氯吲哚‑3‑乙酸的制备方法 |
| WO2019099687A1 (en) * | 2017-11-16 | 2019-05-23 | Antigenesis Llc | Systems and methods for lysosome induced immunogenic cell death |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA957281A (en) * | 1970-02-03 | 1974-11-05 | Nathan N. Share | Pharmaceutical compositions containing indole-3-acetic acid derivatives as a skeletal muscle stimulant |
| US3901914A (en) * | 1973-11-01 | 1975-08-26 | Merck & Co Inc | 1-(substituted phosphinothioyl, phosphinyl or phosphino)-substituted indole-3-acetic acids |
| GB8705477D0 (en) | 1987-03-09 | 1987-04-15 | Carlton Med Prod | Drug delivery systems |
| ZA939516B (en) * | 1992-12-22 | 1994-06-06 | Smithkline Beecham Corp | Endothelin receptor antagonists |
| IL109311A0 (en) * | 1993-04-16 | 1994-07-31 | Lilly Co Eli | 1H-indole-3-acetamide sPla2 inhibitors |
| GB9609641D0 (en) * | 1996-05-09 | 1996-07-10 | Pfizer Ltd | Compounds useful in therapy |
-
2000
- 2000-06-30 GB GBGB0016162.0A patent/GB0016162D0/en not_active Ceased
-
2001
- 2001-06-28 DE DE60101914T patent/DE60101914T2/de not_active Expired - Fee Related
- 2001-06-28 AU AU2001267690A patent/AU2001267690A1/en not_active Abandoned
- 2001-06-28 WO PCT/GB2001/002872 patent/WO2002002110A1/en not_active Ceased
- 2001-06-28 US US10/311,332 patent/US6890948B1/en not_active Expired - Fee Related
- 2001-06-28 AT AT01945476T patent/ATE258436T1/de not_active IP Right Cessation
- 2001-06-28 EP EP01945476A patent/EP1296676B1/de not_active Expired - Lifetime
- 2001-06-28 ES ES01945476T patent/ES2215138T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GB0016162D0 (en) | 2000-08-23 |
| US6890948B1 (en) | 2005-05-10 |
| EP1296676A1 (de) | 2003-04-02 |
| EP1296676B1 (de) | 2004-01-28 |
| ES2215138T3 (es) | 2004-10-01 |
| DE60101914D1 (de) | 2004-03-04 |
| AU2001267690A1 (en) | 2002-01-14 |
| WO2002002110A1 (en) | 2002-01-10 |
| DE60101914T2 (de) | 2004-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |