ATE258677T1 - Verfahren zur schnellen und gleichzeitigen analyse nukleierter roter blutzellen - Google Patents
Verfahren zur schnellen und gleichzeitigen analyse nukleierter roter blutzellenInfo
- Publication number
- ATE258677T1 ATE258677T1 AT95940838T AT95940838T ATE258677T1 AT E258677 T1 ATE258677 T1 AT E258677T1 AT 95940838 T AT95940838 T AT 95940838T AT 95940838 T AT95940838 T AT 95940838T AT E258677 T1 ATE258677 T1 AT E258677T1
- Authority
- AT
- Austria
- Prior art keywords
- scatter
- nrbc
- signal
- blood cells
- red blood
- Prior art date
Links
- 210000003743 erythrocyte Anatomy 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 210000000265 leukocyte Anatomy 0.000 abstract 4
- 210000004369 blood Anatomy 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000009089 cytolysis Effects 0.000 abstract 1
- 210000000805 cytoplasm Anatomy 0.000 abstract 1
- 238000000684 flow cytometry Methods 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/356,932 US5559037A (en) | 1994-12-15 | 1994-12-15 | Method for rapid and simultaneous analysis of nucleated red blood cells |
| PCT/US1995/015371 WO1996018878A1 (en) | 1994-12-15 | 1995-11-28 | Method for rapid and simultaneous analysis of nucleated red blood cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE258677T1 true ATE258677T1 (de) | 2004-02-15 |
Family
ID=23403561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95940838T ATE258677T1 (de) | 1994-12-15 | 1995-11-28 | Verfahren zur schnellen und gleichzeitigen analyse nukleierter roter blutzellen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5559037A (de) |
| EP (1) | EP0797762B1 (de) |
| JP (1) | JP2938976B2 (de) |
| AT (1) | ATE258677T1 (de) |
| CA (1) | CA2207396C (de) |
| DE (1) | DE69532511T2 (de) |
| ES (1) | ES2215181T3 (de) |
| WO (1) | WO1996018878A1 (de) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6509192B1 (en) * | 1992-02-24 | 2003-01-21 | Coulter International Corp. | Quality control method |
| US5879900A (en) * | 1994-12-15 | 1999-03-09 | Abbott Laboratories | Method for simultaneous analysis of cell viability, nucleated red blood cells and white blood cell differentials |
| DE69638209D1 (de) * | 1995-12-15 | 2010-08-12 | Abbott Lab | Verfahren für gleichzeitige analyse von zelllebensfähigkeit, nukleierten roten blutkörperchen und leukozytendifferential |
| US5817519A (en) * | 1995-12-28 | 1998-10-06 | Bayer Corporation | Automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples |
| US6025201A (en) * | 1995-12-28 | 2000-02-15 | Bayer Corporation | Highly sensitive, accurate, and precise automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples |
| US5858790A (en) * | 1996-06-26 | 1999-01-12 | Abbott Laboratories | Hematology reference control and method of preparation |
| JP2001506005A (ja) * | 1996-12-11 | 2001-05-08 | ナイコメッド・アマーシャム・ピーエルシー | 細胞の選択的溶解 |
| US5874311A (en) * | 1997-11-21 | 1999-02-23 | Coulter International Corp. | Method for differentiation of reticulocytes in blood |
| US5874310A (en) * | 1997-11-21 | 1999-02-23 | Coulter International Corp. | Method for differentiation of nucleated red blood cells |
| US5917584A (en) * | 1997-11-21 | 1999-06-29 | Coulter International Corp. | Method for differentiation of nucleated red blood cells |
| US6911313B2 (en) | 1998-02-06 | 2005-06-28 | Sysmex Corporation | Process for discriminating and counting erythroblasts |
| FR2813891B1 (fr) * | 2000-09-14 | 2005-01-14 | Immunotech Sa | Reactif multifonctionnel pour erythrocytes mettant en jeu des carbamates et applications |
| US7049093B2 (en) * | 2000-11-08 | 2006-05-23 | Sysmex Corporation | Method of classifying and counting nucleated bone marrow cells |
| US6448085B1 (en) * | 2001-04-13 | 2002-09-10 | Sysmex Corporation | Quality control material and calibrator for nucleated red blood cell tested on hematology analyzer |
| US6630990B2 (en) * | 2001-06-05 | 2003-10-07 | Abbott Laboratories | Optical method and apparatus for red blood cell differentiation on a cell-by-cell basis, and simultaneous analysis of white blood cell differentiation |
| US6916658B2 (en) * | 2001-07-27 | 2005-07-12 | Beckman Coulter, Inc. | Method for measurement of immature granulocytes |
| US6472215B1 (en) | 2001-07-27 | 2002-10-29 | Coulter International Corp. | Method of analyzing nucleated red blood cells in a blood sample |
| US6573102B2 (en) | 2001-07-27 | 2003-06-03 | Coulter International Corp. | Lytic reagent composition for determination of nucleated blood cells |
| CN1276252C (zh) | 2001-07-27 | 2006-09-20 | 贝克曼库尔特有限公司 | 有核红细胞的测量方法 |
| US6410330B1 (en) | 2001-07-27 | 2002-06-25 | Coulter International Corp. | Method for measurement of nucleated red blood cells |
| JP4850711B2 (ja) * | 2003-10-02 | 2012-01-11 | ベックマン コールター, インコーポレイテッド | 血液サンプルの有核赤血球の光学測定のリファレンスコントロール |
| US7198953B2 (en) * | 2003-10-12 | 2007-04-03 | Beckman Coulter, Inc. | Method of using a reference control composition for measurement of nucleated red blood cells |
| US7195919B2 (en) * | 2003-12-19 | 2007-03-27 | Beckman Coulter, Inc. | Hematology controls for reticulocytes and nucleated red blood cells |
| US7008792B2 (en) * | 2004-02-10 | 2006-03-07 | Beckman Coulter, Inc. | Method of measurement of nucleated red blood cells |
| US7208319B2 (en) * | 2004-02-10 | 2007-04-24 | Beckman Coulter, Inc. | Method of measurement of nucleated red blood cells |
| US7135341B2 (en) * | 2004-04-07 | 2006-11-14 | Beckman Coulter, Inc. | Reference control containing a nucleated red blood cell component |
| US7625712B2 (en) * | 2004-05-21 | 2009-12-01 | Beckman Coulter, Inc. | Method for a fully automated monoclonal antibody-based extended differential |
| US7390662B2 (en) * | 2005-11-09 | 2008-06-24 | Beckman Coulter, Inc. | Method and apparatus for performing platelet measurement |
| US7354767B2 (en) * | 2006-03-16 | 2008-04-08 | Beckman Coulter, Inc. | Reference control composition containing a nucleated red blood cell component made of non-nucleated blood cells |
| CN1945326A (zh) * | 2006-10-13 | 2007-04-11 | 江西特康科技有限公司 | 基于视觉形态的五分类全血细胞分析方法 |
| US7674622B2 (en) * | 2006-12-22 | 2010-03-09 | Abbott Laboratories, Inc. | Method for determination of nucleated red blood cells and leukocytes in a whole blood sample in an automated hematology analyzer |
| CN101349644B (zh) * | 2007-07-20 | 2012-06-27 | 深圳迈瑞生物医疗电子股份有限公司 | 一种白细胞分类试剂和其使用方法 |
| US8102161B2 (en) * | 2007-09-25 | 2012-01-24 | Tdk Corporation | Stable output in a switching power supply by smoothing the output of the secondary coil |
| CN101475754A (zh) * | 2008-01-04 | 2009-07-08 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类荧光染料,组合物及在生物样品染色中的用途 |
| CN101602762B (zh) * | 2008-06-10 | 2013-10-16 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类化合物、其制备方法及应用 |
| US8148101B2 (en) * | 2008-07-22 | 2012-04-03 | Abbott Laboratories | Method for classifying and counting bacteria in body fluids |
| CN101726579B (zh) * | 2008-10-17 | 2014-06-18 | 深圳迈瑞生物医疗电子股份有限公司 | 血液检测试剂和方法 |
| CN101723874B (zh) * | 2008-10-31 | 2013-09-11 | 深圳迈瑞生物医疗电子股份有限公司 | 花菁类化合物及其在生物样品染色中的用途 |
| CN101750476B (zh) * | 2008-12-08 | 2015-06-03 | 深圳迈瑞生物医疗电子股份有限公司 | 血液分析试剂及其使用方法 |
| CN101750274B (zh) * | 2008-12-17 | 2014-06-25 | 深圳迈瑞生物医疗电子股份有限公司 | 白细胞分类计数试剂、试剂盒以及白细胞分类计数的方法 |
| JP5871792B2 (ja) | 2009-04-27 | 2016-03-01 | アボット・ラボラトリーズAbbott Laboratories | 自動血液分析器において、レーザーからの前方散乱を用いることによる、赤血球細胞を白血球細胞から判別する方法 |
| CN101988082B (zh) * | 2009-07-31 | 2015-04-08 | 深圳迈瑞生物医疗电子股份有限公司 | 白细胞分类计数试剂、试剂盒及其制备方法和白细胞分类计数的方法 |
| CN102115456B (zh) * | 2009-12-30 | 2014-08-20 | 深圳迈瑞生物医疗电子股份有限公司 | 花菁类化合物,包含所述化合物的组合物及其在细胞检测中的用途 |
| US9097704B2 (en) | 2010-05-05 | 2015-08-04 | Abbott Laboratories | Method for hematology analysis |
| US20120274925A1 (en) * | 2011-04-26 | 2012-11-01 | Yong Chen | Axial light loss sensor system for flow cytometery |
| CN103917868B (zh) | 2011-05-04 | 2016-08-24 | 雅培制药有限公司 | 嗜碱性粒细胞分析系统和方法 |
| ES2927316T3 (es) | 2011-05-04 | 2022-11-04 | Abbott Lab | Sistema y método de análisis de glóbulos blancos |
| ES2902648T3 (es) * | 2011-05-04 | 2022-03-29 | Abbott Lab | Método de análisis de glóbulos rojos nucleados y analizador hematológico automatizado |
| DE102014107837B4 (de) * | 2014-06-04 | 2021-09-02 | Presens Precision Sensing Gmbh | Optischer Sensor zum quantitativen Nachweis eines Analyten in einer Probe und Verfahren zur Herstellung des Sensors |
| JP6318026B2 (ja) * | 2014-06-26 | 2018-04-25 | アズビル株式会社 | 粒子検出装置及び粒子の検出方法 |
| JP6228085B2 (ja) | 2014-08-27 | 2017-11-08 | シスメックス株式会社 | 検体分析装置及び検体分析方法 |
| CN106687810B (zh) * | 2014-12-31 | 2019-10-22 | 深圳迈瑞生物医疗电子股份有限公司 | 一种非诊断目的的有核红细胞报警方法、装置及流式细胞分析仪 |
| EP3943912B1 (de) * | 2015-02-12 | 2025-08-20 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Zellanalysator und teilchensortierungsverfahren und -vorrichtung |
| LT3150988T (lt) * | 2015-10-01 | 2021-06-25 | Nanotemper Technologies Gmbh | Dalelių stabilumo ir agregacijos optinio matavimo sistema bei būdas |
| WO2018081880A1 (en) * | 2016-11-07 | 2018-05-11 | Kertesz Geza | Equipment for carrying out hemograms |
| EP4462126A4 (de) * | 2021-12-31 | 2025-07-23 | Shenzhen Mindray Biomedical Electronics Co Ltd | Blutzellenanalysegerät, verfahren und verwendung von infektionsmarkerparametern |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4284412A (en) * | 1979-07-13 | 1981-08-18 | Ortho Diagnostics, Inc. | Method and apparatus for automated identification and enumeration of specified blood cell subclasses |
| US4544546A (en) * | 1980-04-21 | 1985-10-01 | Abbott Laboratories | Fluorescent nucleic acid stains |
| US4492752A (en) * | 1982-09-03 | 1985-01-08 | Ortho Diagnostics Systems Inc. | Method for discriminating between unstained and absorbing dye stained cells |
| JPS59184841A (ja) * | 1983-04-05 | 1984-10-20 | ベクトン・デイツキンソン・アンド・カンパニ− | サンプル中の白血球のサブクラスを識別する方法および装置 |
| US5188935A (en) * | 1984-05-31 | 1993-02-23 | Coulter Electronics, Inc. | Reagent system and method for identification, enumeration and examination of classes and subclasses of blood leukocytes |
| US4751179A (en) * | 1984-05-31 | 1988-06-14 | Coulter Electronics, Inc. | Method and reagents for differential determination of four populations of leukocytes in blood |
| US4727020A (en) * | 1985-02-25 | 1988-02-23 | Becton, Dickinson And Company | Method for analysis of subpopulations of blood cells |
| US4978624A (en) * | 1985-09-06 | 1990-12-18 | Technicon Instruments Corporation | Reagent for the determination of a differential white blood cell count |
| KR970007077B1 (ko) * | 1987-03-13 | 1997-05-02 | 코울터 일렉트로닉스 인커퍼레이티드 | 광산란 기술을 이용한 다중-부분식별 분석 방법 |
| US4882284A (en) * | 1987-04-13 | 1989-11-21 | Ortho Pharmaceutical Corporation | Method for quantitating and differentiating white blood cells |
| JPS6435345A (en) * | 1987-07-31 | 1989-02-06 | Canon Kk | Particle analyzing device |
| US4987086A (en) * | 1987-11-30 | 1991-01-22 | Becton, Dickinson And Company | Method for analysis of subpopulations of cells |
| US5047321A (en) * | 1988-06-15 | 1991-09-10 | Becton Dickinson & Co. | Method for analysis of cellular components of a fluid |
| JP2927979B2 (ja) * | 1991-02-22 | 1999-07-28 | シスメックス株式会社 | フローサイトメトリーによる赤芽球の分類方法 |
| EP0685994B1 (de) * | 1993-02-25 | 2007-03-21 | Abbott Laboratories | Mehrzweckreagenzsystem zur schnellen lysierung von vollblutproben |
-
1994
- 1994-12-15 US US08/356,932 patent/US5559037A/en not_active Expired - Lifetime
-
1995
- 1995-11-28 WO PCT/US1995/015371 patent/WO1996018878A1/en not_active Ceased
- 1995-11-28 EP EP95940838A patent/EP0797762B1/de not_active Expired - Lifetime
- 1995-11-28 AT AT95940838T patent/ATE258677T1/de not_active IP Right Cessation
- 1995-11-28 CA CA002207396A patent/CA2207396C/en not_active Expired - Fee Related
- 1995-11-28 DE DE69532511T patent/DE69532511T2/de not_active Expired - Lifetime
- 1995-11-28 ES ES95940838T patent/ES2215181T3/es not_active Expired - Lifetime
- 1995-11-28 JP JP8518976A patent/JP2938976B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH10504398A (ja) | 1998-04-28 |
| EP0797762B1 (de) | 2004-01-28 |
| CA2207396A1 (en) | 1996-06-20 |
| ES2215181T3 (es) | 2004-10-01 |
| CA2207396C (en) | 2007-08-07 |
| DE69532511D1 (de) | 2004-03-04 |
| EP0797762A1 (de) | 1997-10-01 |
| WO1996018878A1 (en) | 1996-06-20 |
| US5559037A (en) | 1996-09-24 |
| JP2938976B2 (ja) | 1999-08-25 |
| DE69532511T2 (de) | 2004-11-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0797762 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |