ATE260288T1 - (1s, cis)-4-(2-amino-9h-purin-9-yl)-2-cyclopenten-1- ethanol analogue als antiviral - Google Patents

(1s, cis)-4-(2-amino-9h-purin-9-yl)-2-cyclopenten-1- ethanol analogue als antiviral

Info

Publication number
ATE260288T1
ATE260288T1 AT00984009T AT00984009T ATE260288T1 AT E260288 T1 ATE260288 T1 AT E260288T1 AT 00984009 T AT00984009 T AT 00984009T AT 00984009 T AT00984009 T AT 00984009T AT E260288 T1 ATE260288 T1 AT E260288T1
Authority
AT
Austria
Prior art keywords
cyclopent
purine
antiviral
analogue
cis
Prior art date
Application number
AT00984009T
Other languages
English (en)
Inventor
Susan Mary Daluge
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE260288T1 publication Critical patent/ATE260288T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT00984009T 1999-12-10 2000-12-07 (1s, cis)-4-(2-amino-9h-purin-9-yl)-2-cyclopenten-1- ethanol analogue als antiviral ATE260288T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17022599P 1999-12-10 1999-12-10
PCT/US2000/033204 WO2001042256A1 (en) 1999-12-10 2000-12-07 ANALOGS OF (1S, cis)-4-(2-AMINO-9H-PURIN-9-YL)-2-CYCLOPENTENE-1-METHANOL AS ANTIVIRAL

Publications (1)

Publication Number Publication Date
ATE260288T1 true ATE260288T1 (de) 2004-03-15

Family

ID=22619059

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00984009T ATE260288T1 (de) 1999-12-10 2000-12-07 (1s, cis)-4-(2-amino-9h-purin-9-yl)-2-cyclopenten-1- ethanol analogue als antiviral

Country Status (9)

Country Link
EP (1) EP1235833B1 (de)
JP (1) JP2003516409A (de)
AR (1) AR026913A1 (de)
AT (1) ATE260288T1 (de)
AU (1) AU2068901A (de)
DE (1) DE60008580T2 (de)
ES (1) ES2213061T3 (de)
PE (1) PE20010915A1 (de)
WO (1) WO2001042256A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201513601D0 (en) * 2015-07-31 2015-09-16 Univ Liverpool Antiviral compounds
TW202019942A (zh) * 2018-07-27 2020-06-01 日商富士軟片股份有限公司 環戊烯嘌呤衍生物或其鹽
EP3831836B1 (de) 2018-07-27 2023-09-06 FUJIFILM Corporation Cyclobutylpurinderivat oder salz davon
WO2024107859A1 (en) * 2022-11-15 2024-05-23 Rome Therapeutics, Inc. Cyclopentene-oxymethylene phosphonamidates and related compounds and their use in treating medical conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
GB9505025D0 (en) * 1995-03-13 1995-05-03 Medical Res Council Chemical compounds
GB9821058D0 (en) * 1998-09-28 1998-11-18 Univ Cardiff Chemical compound
CZ20012908A3 (cs) * 1999-02-12 2002-10-16 Glaxo Group Limited Analogy (1R, cis)-4-(6-amino-9H-purin-9-yl)-2-cyklopenten-1-methanolu

Also Published As

Publication number Publication date
DE60008580T2 (de) 2004-08-05
AR026913A1 (es) 2003-03-05
AU2068901A (en) 2001-06-18
WO2001042256A1 (en) 2001-06-14
PE20010915A1 (es) 2001-09-29
ES2213061T3 (es) 2004-08-16
EP1235833A1 (de) 2002-09-04
DE60008580D1 (en) 2004-04-01
EP1235833B1 (de) 2004-02-25
JP2003516409A (ja) 2003-05-13

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties