ATE260340T1 - Molekulare klonierung und charakterisierung von molekülen, welche verwandt sind mit relaxin und liganden der insulinfamilie - Google Patents

Molekulare klonierung und charakterisierung von molekülen, welche verwandt sind mit relaxin und liganden der insulinfamilie

Info

Publication number
ATE260340T1
ATE260340T1 AT96937801T AT96937801T ATE260340T1 AT E260340 T1 ATE260340 T1 AT E260340T1 AT 96937801 T AT96937801 T AT 96937801T AT 96937801 T AT96937801 T AT 96937801T AT E260340 T1 ATE260340 T1 AT E260340T1
Authority
AT
Austria
Prior art keywords
relaxin
related factor
provides
factor
well
Prior art date
Application number
AT96937801T
Other languages
English (en)
Inventor
Samuel Davis
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Application granted granted Critical
Publication of ATE260340T1 publication Critical patent/ATE260340T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/64—Relaxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT96937801T 1995-11-03 1996-11-01 Molekulare klonierung und charakterisierung von molekülen, welche verwandt sind mit relaxin und liganden der insulinfamilie ATE260340T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US622195P 1995-11-03 1995-11-03
US1201696P 1996-02-21 1996-02-21
PCT/US1996/017342 WO1997016549A2 (en) 1995-11-03 1996-11-01 Molecular cloning and characterization of molecules related to relaxin and the insulin family of ligands

Publications (1)

Publication Number Publication Date
ATE260340T1 true ATE260340T1 (de) 2004-03-15

Family

ID=26675338

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96937801T ATE260340T1 (de) 1995-11-03 1996-11-01 Molekulare klonierung und charakterisierung von molekülen, welche verwandt sind mit relaxin und liganden der insulinfamilie

Country Status (10)

Country Link
EP (1) EP0866861B1 (de)
JP (1) JPH11514524A (de)
AT (1) ATE260340T1 (de)
AU (1) AU713773B2 (de)
CA (1) CA2236297A1 (de)
DE (1) DE69631678T2 (de)
DK (1) DK0866861T3 (de)
ES (1) ES2216070T3 (de)
PT (1) PT866861E (de)
WO (1) WO1997016549A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998005782A1 (en) * 1996-08-02 1998-02-12 Zymogenetics, Inc. Testis-specific insulin homolog polypeptides
US6709659B1 (en) 1996-08-02 2004-03-23 Zymogenetics, Inc. Antibodies that bind testis-specific insulin homolog polypeptides
AU729821B2 (en) * 1996-10-15 2001-02-08 Zymogenetics Inc. Insulin homologs
US6114307A (en) * 1996-12-16 2000-09-05 Zymogenetics, Inc. Methods for stimulating pancreatic islet cell regeneration
US20050032683A1 (en) 2000-10-04 2005-02-10 Amento Edward P. Methods of modulating apoptosis by administration of relaxin agonists or antagonists
RU2014103288A (ru) * 2011-07-01 2015-08-10 Байер Интеллектчуал Проперти Гмбх Слитые полипептиды релаксина и их применение
US20140335108A1 (en) * 2011-12-12 2014-11-13 Trustees Of Boston University Utility of insulin-like 6 (insl6) for the treatment of autoimmune diseases
IL263079B2 (en) 2016-05-18 2024-05-01 Modernatx Inc Polynucleotides encoding relaxin

Also Published As

Publication number Publication date
EP0866861B1 (de) 2004-02-25
DK0866861T3 (da) 2004-06-21
ES2216070T3 (es) 2004-10-16
CA2236297A1 (en) 1997-05-09
WO1997016549A3 (en) 1997-06-19
EP0866861A2 (de) 1998-09-30
DE69631678D1 (de) 2004-04-01
AU713773B2 (en) 1999-12-09
DE69631678T2 (de) 2005-01-13
AU7526196A (en) 1997-05-22
PT866861E (pt) 2004-05-31
WO1997016549A2 (en) 1997-05-09
JPH11514524A (ja) 1999-12-14

Similar Documents

Publication Publication Date Title
Shimonaka et al. Follistatin binds to both activin and inhibin through the common beta-subunit
CA2064689C (en) Stabilized protein or peptide conjugates
ATE425181T1 (de) Therapeutische zusammensetzungen aus antikorper und antisens nukleinsäuren gegen serrate
ATE444361T1 (de) Il-17 und il-17r homologe polypeptide und deren therapeutische verwendungen
EA200901129A1 (ru) Нуклеиновые кислоты и полипептиды нового рецептора
Lappi et al. Biological and chemical characterization of basic FGF-saporin mitotoxin
AR062867A2 (es) Proteinas de enlace a interleuquina -18, (il- 18bp), secuencias de adn que codifican para la il -18 bp, secuencias de adnc, un vehiculo de expresion replicable, celula huesped, un proceso para su produccion y aislacion, anticuerpos, composiciones farmaceuticas, el uso de dichas composiciones para la
JP6949832B2 (ja) タンパク質コンジュゲート
EA200000331A1 (ru) Фармацевтические композиции, содержащие белок плазмы
UA48105C2 (uk) ФРАГМЕНТ ДНК, ЯКИЙ КОДУЄ БІЛОК РОДИНИ TGF-<font face="Symbol">b</font> (ВАРІАНТИ), РЕКОМБІНАНТНА МОЛЕКУЛА ДНК (ВАРІАНТИ), КЛІТИНА-ХАЗЯЇН (ВАРІАНТИ), СПОСІБ ОДЕРЖАННЯ БІЛКУ РОДИНИ TGF-<font face="Symbol">b</font> (ВАРІАНТИ), БІЛОК РОДИНИ TGF-<font face="Symbol">b</font> (ВАРІАНТИ), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ (ВАРІАНТИ), АНТИТІЛО АБО ФРАГМЕНТ АНТИТІЛА (ВАРІАНТИ), МОЛЕКУЛА КДНК (ВАРІАНТИ)
BRPI0411112A (pt) proteìna de fusão heteróloga, polinucleotìdeo, vetor, célula hospedeira, processo para produzir uma proteìna de fusão heteróloga, método para tratar um paciente, e, uso de proteìna de fusão heteróloga
PT73161A (fr) Procede pour la preparation de derives de n-(vynblastinoyl-23) aux amino-acids et peptides et son application terapeutique
CN101663317A (zh) 胰高血糖素样蛋白-1受体glp-1r激动剂化合物
ATE365744T1 (de) Nukleinsäuremoleküle, proteine und peptide, die im zusammenhang stehen mit dickdarmzellen und dickdarm-krebszellen
Murar et al. Chemical synthesis of interleukin‐2 and disulfide stabilizing analogues
RU93045577A (ru) Слитные полипептиды
CN114206908A (zh) 具有改善的稳定性的经设计的锚蛋白重复结构域
ATE260340T1 (de) Molekulare klonierung und charakterisierung von molekülen, welche verwandt sind mit relaxin und liganden der insulinfamilie
KR980002066A (ko) 변이형 인간 성장호르몬 및 그의 용도
Rasche et al. PROLink Single Step Circularization and Purification Procedure for the Generation of an Improved Variant of Human Growth Hormone
MX9203175A (es) Composicion de implante que contiene un peptido, polipeptido o proteina biologicamente activa y procedimiento para su preparacion.
JP4761963B2 (ja) 癌療法で用いる修飾されたサイトカイン
Spiegelberg et al. Human myeloma IgA half-molecules.
DE69328060D1 (de) Angiotensin-II Typ-1 Rezeptor und dessen Herstellung
JP7766608B2 (ja) プロテアーゼプロセシングした分子

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0866861

Country of ref document: EP

REN Ceased due to non-payment of the annual fee