ATE260676T1 - Verfahren zur herstellung einer körnigen porösen trockenen gelzusammensetzung von sucralfate - Google Patents

Verfahren zur herstellung einer körnigen porösen trockenen gelzusammensetzung von sucralfate

Info

Publication number
ATE260676T1
ATE260676T1 AT99927877T AT99927877T ATE260676T1 AT E260676 T1 ATE260676 T1 AT E260676T1 AT 99927877 T AT99927877 T AT 99927877T AT 99927877 T AT99927877 T AT 99927877T AT E260676 T1 ATE260676 T1 AT E260676T1
Authority
AT
Austria
Prior art keywords
sucralfate
preparing
gel composition
dry gel
contain
Prior art date
Application number
AT99927877T
Other languages
English (en)
Inventor
Giorgio Zagnoli
Paolo Colombo
Loretta Maggi
Fabrizio Cudazzo
Original Assignee
Lisapharma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lisapharma Spa filed Critical Lisapharma Spa
Application granted granted Critical
Publication of ATE260676T1 publication Critical patent/ATE260676T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
AT99927877T 1998-07-30 1999-06-04 Verfahren zur herstellung einer körnigen porösen trockenen gelzusammensetzung von sucralfate ATE260676T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI001785A IT1301969B1 (it) 1998-07-30 1998-07-30 Sucralfato gel secco granulare e poroso procedimento per la suapreparazione, e composizioni farmaceutiche solide che lo contengono
PCT/EP1999/003879 WO2000006201A1 (en) 1998-07-30 1999-06-04 Process for the preparation of granular and porous sucralfate dry gel

Publications (1)

Publication Number Publication Date
ATE260676T1 true ATE260676T1 (de) 2004-03-15

Family

ID=11380570

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99927877T ATE260676T1 (de) 1998-07-30 1999-06-04 Verfahren zur herstellung einer körnigen porösen trockenen gelzusammensetzung von sucralfate

Country Status (9)

Country Link
US (2) US6706286B1 (de)
EP (1) EP1100540B1 (de)
AT (1) ATE260676T1 (de)
AU (1) AU4506999A (de)
DE (1) DE69915301T2 (de)
ES (1) ES2217766T3 (de)
IT (1) IT1301969B1 (de)
PT (1) PT1100540E (de)
WO (1) WO2000006201A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL204106B1 (pl) * 2000-02-28 2009-12-31 Pharmakodex Ltd Zestaw do dostarczania środka terapeutycznego
WO2014151565A1 (en) 2013-03-15 2014-09-25 The Brigham And Women's Hospital, Inc. Compounds to modulate intestinal absorption of nutrients
US10973846B2 (en) 2015-09-24 2021-04-13 The Brigham And Women's Hospital, Inc. Water-activated mucoadhesive compositions to reduce intestinal absorption of nutrients
KR101749425B1 (ko) * 2015-11-17 2017-06-22 연세대학교 산학협력단 난용성 약물의 서방형 제제
JP6855732B2 (ja) * 2016-09-29 2021-04-07 ライオン株式会社 粉体組成物及びその製造方法
CN109431972B (zh) * 2018-11-20 2022-02-22 昆明积大制药股份有限公司 一种粒径为100nm—500nm的硫糖铝凝胶的成胶方法
CN114269386A (zh) 2019-06-10 2022-04-01 布里格姆及妇女医院股份有限公司 水活化的粘膜粘附性组合物和递送生物活性物质的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196190B (it) * 1984-07-12 1988-11-10 Lisapharma Spa Forma farmaceutica solida orale ad azione sequenziale per la somministrazione di farmaci ad effetto collaterale ulcerogeno
IT1203901B (it) * 1987-04-15 1989-02-23 Lisapharma Spa Composizioni farmaceutiche sotto forma di sospensioni stabili di sucralfato esenti da agenti sospendenti
IT1274735B (it) 1994-08-25 1997-07-24 Enosys S P A Farmaco e vettore per le patologie infiammatorie ed erosive del tratto gastrointestinale a base di sucralfato allo stato di gel secco
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability

Also Published As

Publication number Publication date
PT1100540E (pt) 2004-07-30
IT1301969B1 (it) 2000-07-20
WO2000006201A1 (en) 2000-02-10
US20030206950A1 (en) 2003-11-06
DE69915301T2 (de) 2005-03-10
ES2217766T3 (es) 2004-11-01
EP1100540A1 (de) 2001-05-23
AU4506999A (en) 2000-02-21
DE69915301D1 (de) 2004-04-08
EP1100540B1 (de) 2004-03-03
US6773722B2 (en) 2004-08-10
ITMI981785A1 (it) 2000-01-30
ITMI981785A0 (it) 1998-07-30
US6706286B1 (en) 2004-03-16

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