ATE260898T1 - Substituierte vinylpyridinderivate und arzneimittel, die diese enthalten - Google Patents
Substituierte vinylpyridinderivate und arzneimittel, die diese enthaltenInfo
- Publication number
- ATE260898T1 ATE260898T1 AT97940447T AT97940447T ATE260898T1 AT E260898 T1 ATE260898 T1 AT E260898T1 AT 97940447 T AT97940447 T AT 97940447T AT 97940447 T AT97940447 T AT 97940447T AT E260898 T1 ATE260898 T1 AT E260898T1
- Authority
- AT
- Austria
- Prior art keywords
- derivative
- salt
- products containing
- containing same
- medicinal products
- Prior art date
Links
- KGIGUEBEKRSTEW-UHFFFAOYSA-N 2-vinylpyridine Chemical class C=CC1=CC=CC=N1 KGIGUEBEKRSTEW-UHFFFAOYSA-N 0.000 title abstract 2
- 229940126601 medicinal product Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 125000002560 nitrile group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000006433 tumor necrosis factor production Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25294496 | 1996-09-25 | ||
| PCT/JP1997/003354 WO1998013348A1 (en) | 1996-09-25 | 1997-09-22 | Substituted vinylpyridine derivatives and drugs containing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE260898T1 true ATE260898T1 (de) | 2004-03-15 |
Family
ID=17244339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97940447T ATE260898T1 (de) | 1996-09-25 | 1997-09-22 | Substituierte vinylpyridinderivate und arzneimittel, die diese enthalten |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5935977A (de) |
| EP (1) | EP0882714B1 (de) |
| KR (1) | KR100517452B1 (de) |
| CN (1) | CN1169792C (de) |
| AT (1) | ATE260898T1 (de) |
| DE (1) | DE69727915T2 (de) |
| ES (1) | ES2217428T3 (de) |
| TW (1) | TW517056B (de) |
| WO (1) | WO1998013348A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3775685B2 (ja) * | 1993-07-28 | 2006-05-17 | ローン−プーラン・ロレ・リミテツド | Ｐｄｅ▲ｉｖ▼およびｔｎｆ抑制剤としての化合物 |
| US6368815B1 (en) | 1999-03-29 | 2002-04-09 | Warner-Lambert Company | Screening of molecules that inhibit human phosphodiesterase 4A produced by non-recombinant cell lines |
| WO2001030757A1 (en) * | 1999-10-28 | 2001-05-03 | Microcide Pharmaceuticals, Inc. | Drug discharge pump inhibitors |
| US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
| GB0020498D0 (en) | 2000-08-18 | 2000-10-11 | Sterix Ltd | Compound |
| US7056917B2 (en) * | 2001-04-26 | 2006-06-06 | Daiichi Pharmaceutical Co., Ltd. | Drug efflux pump inhibitor |
| US20050009843A1 (en) * | 2001-04-26 | 2005-01-13 | Kiyoshi Nakayama | Medicine for inhibiting drug elimination pump |
| EP2295081B1 (de) | 2001-06-26 | 2018-10-31 | Amgen Inc. | Antikörper gegen OPGL |
| US20030187026A1 (en) | 2001-12-13 | 2003-10-02 | Qun Li | Kinase inhibitors |
| US6797825B2 (en) | 2001-12-13 | 2004-09-28 | Abbott Laboratories | Protein kinase inhibitors |
| CA2481178A1 (en) * | 2002-04-02 | 2003-10-23 | Tatsuhiro Obata | Phosphodiesterase iv inhibitor containing pyridylacrylamide derivative |
| WO2004060911A2 (en) | 2002-12-30 | 2004-07-22 | Amgen Inc. | Combination therapy with co-stimulatory factors |
| US7262196B2 (en) * | 2003-02-11 | 2007-08-28 | Prosidion Limited | Tri(cyclo) substituted amide glucokinase activator compounds |
| GB0411562D0 (en) | 2004-05-24 | 2004-06-23 | Sterix Ltd | Compound |
| GB0412492D0 (en) | 2004-06-04 | 2004-07-07 | Sterix Ltd | Compound |
| GB0513702D0 (en) | 2005-07-04 | 2005-08-10 | Sterix Ltd | Compound |
| GB0702446D0 (en) | 2007-02-08 | 2007-03-21 | Sterix Ltd | Composition |
| GB0706072D0 (en) | 2007-03-28 | 2007-05-09 | Sterix Ltd | Compound |
| GB0722779D0 (en) | 2007-11-20 | 2008-01-02 | Sterix Ltd | Compound |
| GB0914767D0 (en) | 2009-08-24 | 2009-09-30 | Sterix Ltd | Compound |
| KR101599804B1 (ko) * | 2012-08-28 | 2016-03-04 | (주)로커스 | 관 삽입 확인장치 및 관을 대상물에 연결시키는 방법 |
| CN104955820A (zh) * | 2012-11-28 | 2015-09-30 | 赛诺菲 | 4-(环丙基甲氧基)-n-(3,5-二氯-1-氧化-吡啶-4-基)-5-甲氧基吡啶-2-甲酰胺的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4673684A (en) * | 1984-04-04 | 1987-06-16 | Terumo Corporation | Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient |
| GB9304919D0 (en) * | 1993-03-10 | 1993-04-28 | Celltech Ltd | Chemical compounds |
| GB9401460D0 (en) * | 1994-01-26 | 1994-03-23 | Rhone Poulenc Rorer Ltd | Compositions of matter |
| CN1182419A (zh) * | 1996-03-15 | 1998-05-20 | 爱斯制药株式会社 | 新型的吡啶衍生物和含有它作为有效成分的药物 |
-
1997
- 1997-09-22 ES ES97940447T patent/ES2217428T3/es not_active Expired - Lifetime
- 1997-09-22 AT AT97940447T patent/ATE260898T1/de not_active IP Right Cessation
- 1997-09-22 US US09/068,986 patent/US5935977A/en not_active Expired - Lifetime
- 1997-09-22 DE DE69727915T patent/DE69727915T2/de not_active Expired - Fee Related
- 1997-09-22 EP EP97940447A patent/EP0882714B1/de not_active Expired - Lifetime
- 1997-09-22 WO PCT/JP1997/003354 patent/WO1998013348A1/ja not_active Ceased
- 1997-09-22 CN CNB971914923A patent/CN1169792C/zh not_active Expired - Fee Related
- 1997-09-22 KR KR1019980703387A patent/KR100517452B1/ko not_active Expired - Fee Related
- 1997-09-24 TW TW086113884A patent/TW517056B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1206407A (zh) | 1999-01-27 |
| ES2217428T3 (es) | 2004-11-01 |
| WO1998013348A1 (en) | 1998-04-02 |
| KR100517452B1 (ko) | 2007-03-15 |
| KR19990067377A (ko) | 1999-08-16 |
| EP0882714B1 (de) | 2004-03-03 |
| EP0882714A1 (de) | 1998-12-09 |
| EP0882714A4 (de) | 2000-02-09 |
| TW517056B (en) | 2003-01-11 |
| DE69727915T2 (de) | 2004-08-19 |
| DE69727915D1 (de) | 2004-04-08 |
| US5935977A (en) | 1999-08-10 |
| CN1169792C (zh) | 2004-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |